Result of FASTA (omim) for
pFN21AB6309
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6309, 258 aa
1>>>pF1KB6309 258 - 258 aa - 258 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5777+/-0.000271; mu= 14.0753+/- 0.017
mean_var=77.8823+/-15.685, 0's: 0 Z-trim(120.7): 13 B-trim: 3 in 1/55
Lambda= 0.145330
statistics sampled from 36250 (36263) to 36250 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.773), E-opt: 0.2 (0.425), width: 16
Scan time: 8.000
The best scores are: opt bits E(85289)
NP_036220 (OMIM: 604951) 6-phosphogluconolactonase ( 258) 1700 365.1 7.2e-101
XP_011526199 (OMIM: 604951) PREDICTED: 6-phosphogl ( 170) 1072 233.3 2.2e-61
XP_016858355 (OMIM: 138090,604931) PREDICTED: GDH/ ( 435) 354 83.0 9.8e-16
XP_016858354 (OMIM: 138090,604931) PREDICTED: GDH/ ( 791) 354 83.2 1.6e-15
XP_006711115 (OMIM: 138090,604931) PREDICTED: GDH/ ( 791) 354 83.2 1.6e-15
NP_004276 (OMIM: 138090,604931) GDH/6PGL endoplasm ( 791) 354 83.2 1.6e-15
XP_005263597 (OMIM: 138090,604931) PREDICTED: GDH/ ( 800) 354 83.2 1.6e-15
NP_001269516 (OMIM: 138090,604931) GDH/6PGL endopl ( 802) 354 83.2 1.6e-15
>>NP_036220 (OMIM: 604951) 6-phosphogluconolactonase [Ho (258 aa)
initn: 1700 init1: 1700 opt: 1700 Z-score: 1931.9 bits: 365.1 E(85289): 7.2e-101
Smith-Waterman score: 1700; 100.0% identity (100.0% similar) in 258 aa overlap (1-258:1-258)
10 20 30 40 50 60
pF1KB6 MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGARARFALGLSGGSLVSMLARELPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGARARFALGLSGGSLVSMLARELPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AVAPAGPASLARWTLGFCDERLVPFDHAESTYGLYRTHLLSRLPIPESQVITINPELPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AVAPAGPASLARWTLGFCDERLVPFDHAESTYGLYRTHLLSRLPIPESQVITINPELPVE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EAAEDYAKKLRQAFQGDSIPVFDLLILGVGPDGHTCSLFPDHPLLQEREKIVAPISDSPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EAAEDYAKKLRQAFQGDSIPVFDLLILGVGPDGHTCSLFPDHPLLQEREKIVAPISDSPK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 PPPQRVTLTLPVLNAARTVIFVATGEGKAAVLKRILEDQEENPLPAALVQPHTGKLCWFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PPPQRVTLTLPVLNAARTVIFVATGEGKAAVLKRILEDQEENPLPAALVQPHTGKLCWFL
190 200 210 220 230 240
250
pF1KB6 DEAAARLLTVPFEKHSTL
::::::::::::::::::
NP_036 DEAAARLLTVPFEKHSTL
250
>>XP_011526199 (OMIM: 604951) PREDICTED: 6-phosphoglucon (170 aa)
initn: 1072 init1: 1072 opt: 1072 Z-score: 1223.0 bits: 233.3 E(85289): 2.2e-61
Smith-Waterman score: 1072; 100.0% identity (100.0% similar) in 162 aa overlap (97-258:9-170)
70 80 90 100 110 120
pF1KB6 PASLARWTLGFCDERLVPFDHAESTYGLYRTHLLSRLPIPESQVITINPELPVEEAAEDY
::::::::::::::::::::::::::::::
XP_011 MEKLRPEETHLLSRLPIPESQVITINPELPVEEAAEDY
10 20 30
130 140 150 160 170 180
pF1KB6 AKKLRQAFQGDSIPVFDLLILGVGPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKKLRQAFQGDSIPVFDLLILGVGPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRV
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB6 TLTLPVLNAARTVIFVATGEGKAAVLKRILEDQEENPLPAALVQPHTGKLCWFLDEAAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLTLPVLNAARTVIFVATGEGKAAVLKRILEDQEENPLPAALVQPHTGKLCWFLDEAAAR
100 110 120 130 140 150
250
pF1KB6 LLTVPFEKHSTL
::::::::::::
XP_011 LLTVPFEKHSTL
160 170
>>XP_016858355 (OMIM: 138090,604931) PREDICTED: GDH/6PGL (435 aa)
initn: 291 init1: 174 opt: 354 Z-score: 403.5 bits: 83.0 E(85289): 9.8e-16
Smith-Waterman score: 354; 33.7% identity (62.6% similar) in 246 aa overlap (8-244:199-432)
10 20 30
pF1KB6 MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGA
:.:.. :.:: . ::. . .:. :
XP_016 QQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAW--SEELISKLANDI--EATAVRAVR
170 180 190 200 210 220
40 50 60 70 80 90
pF1KB6 R-ARFALGLSGGSLVSMLARELPAAVAPAG-PASLARWTLGFCDERLVPFDHAESTYGLY
: ..: :.::::: : ..: :.: : : :. : . ::: ::.. ::..
XP_016 RFGQFHLALSGGSSPVALFQQL--ATAHYGFP--WAHTHLWLVDERCVPLSDPESNFQGL
230 240 250 260 270 280
100 110 120 130 140
pF1KB6 RTHLLSRLPIPESQV----ITINPELPVEE--AAEDYAKKLRQAFQGDSIPVFDLLILGV
..:::... :: .. . .. .: .:: .:. ::... ..: :::..::.
XP_016 QAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALVANSS---FDLVLLGM
290 300 310 320 330
150 160 170 180 190 200
pF1KB6 GPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRVTLTLPVLNAARTVIFVATGEGKA
: :::: ::::. : . :..:. .. ::. : .:..:.::..: :. : .. :. :
XP_016 GADGHTASLFPQSPTGLDGEQLVV-LTTSPSQPHRRMSLSLPLINRAKKVAVLVMGRMKR
340 350 360 370 380 390
210 220 230 240 250
pF1KB6 AVLKRILE-DQEENPLPAALVQPHTGKLCWFLDEAAARLLTVPFEKHSTL
. . . .: . : . : ::.:.: :..: :
XP_016 EITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDAFLG
400 410 420 430
>>XP_016858354 (OMIM: 138090,604931) PREDICTED: GDH/6PGL (791 aa)
initn: 291 init1: 174 opt: 354 Z-score: 399.7 bits: 83.2 E(85289): 1.6e-15
Smith-Waterman score: 354; 33.7% identity (62.6% similar) in 246 aa overlap (8-244:555-788)
10 20 30
pF1KB6 MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGA
:.:.. :.:: . ::. . .:. :
XP_016 QQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAW--SEELISKLANDI--EATAVRAVR
530 540 550 560 570 580
40 50 60 70 80 90
pF1KB6 R-ARFALGLSGGSLVSMLARELPAAVAPAG-PASLARWTLGFCDERLVPFDHAESTYGLY
: ..: :.::::: : ..: :.: : : :. : . ::: ::.. ::..
XP_016 RFGQFHLALSGGSSPVALFQQL--ATAHYGFP--WAHTHLWLVDERCVPLSDPESNFQGL
590 600 610 620 630
100 110 120 130 140
pF1KB6 RTHLLSRLPIPESQV----ITINPELPVEE--AAEDYAKKLRQAFQGDSIPVFDLLILGV
..:::... :: .. . .. .: .:: .:. ::... ..: :::..::.
XP_016 QAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALVANSS---FDLVLLGM
640 650 660 670 680 690
150 160 170 180 190 200
pF1KB6 GPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRVTLTLPVLNAARTVIFVATGEGKA
: :::: ::::. : . :..:. .. ::. : .:..:.::..: :. : .. :. :
XP_016 GADGHTASLFPQSPTGLDGEQLVV-LTTSPSQPHRRMSLSLPLINRAKKVAVLVMGRMKR
700 710 720 730 740 750
210 220 230 240 250
pF1KB6 AVLKRILE-DQEENPLPAALVQPHTGKLCWFLDEAAARLLTVPFEKHSTL
. . . .: . : . : ::.:.: :..: :
XP_016 EITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDAFLG
760 770 780 790
>>XP_006711115 (OMIM: 138090,604931) PREDICTED: GDH/6PGL (791 aa)
initn: 291 init1: 174 opt: 354 Z-score: 399.7 bits: 83.2 E(85289): 1.6e-15
Smith-Waterman score: 354; 33.7% identity (62.6% similar) in 246 aa overlap (8-244:555-788)
10 20 30
pF1KB6 MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGA
:.:.. :.:: . ::. . .:. :
XP_006 QQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAW--SEELISKLANDI--EATAVRAVR
530 540 550 560 570 580
40 50 60 70 80 90
pF1KB6 R-ARFALGLSGGSLVSMLARELPAAVAPAG-PASLARWTLGFCDERLVPFDHAESTYGLY
: ..: :.::::: : ..: :.: : : :. : . ::: ::.. ::..
XP_006 RFGQFHLALSGGSSPVALFQQL--ATAHYGFP--WAHTHLWLVDERCVPLSDPESNFQGL
590 600 610 620 630
100 110 120 130 140
pF1KB6 RTHLLSRLPIPESQV----ITINPELPVEE--AAEDYAKKLRQAFQGDSIPVFDLLILGV
..:::... :: .. . .. .: .:: .:. ::... ..: :::..::.
XP_006 QAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALVANSS---FDLVLLGM
640 650 660 670 680 690
150 160 170 180 190 200
pF1KB6 GPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRVTLTLPVLNAARTVIFVATGEGKA
: :::: ::::. : . :..:. .. ::. : .:..:.::..: :. : .. :. :
XP_006 GADGHTASLFPQSPTGLDGEQLVV-LTTSPSQPHRRMSLSLPLINRAKKVAVLVMGRMKR
700 710 720 730 740 750
210 220 230 240 250
pF1KB6 AVLKRILE-DQEENPLPAALVQPHTGKLCWFLDEAAARLLTVPFEKHSTL
. . . .: . : . : ::.:.: :..: :
XP_006 EITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDAFLG
760 770 780 790
>>NP_004276 (OMIM: 138090,604931) GDH/6PGL endoplasmic b (791 aa)
initn: 291 init1: 174 opt: 354 Z-score: 399.7 bits: 83.2 E(85289): 1.6e-15
Smith-Waterman score: 354; 33.7% identity (62.6% similar) in 246 aa overlap (8-244:555-788)
10 20 30
pF1KB6 MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGA
:.:.. :.:: . ::. . .:. :
NP_004 QQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAW--SEELISKLANDI--EATAVRAVR
530 540 550 560 570 580
40 50 60 70 80 90
pF1KB6 R-ARFALGLSGGSLVSMLARELPAAVAPAG-PASLARWTLGFCDERLVPFDHAESTYGLY
: ..: :.::::: : ..: :.: : : :. : . ::: ::.. ::..
NP_004 RFGQFHLALSGGSSPVALFQQL--ATAHYGFP--WAHTHLWLVDERCVPLSDPESNFQGL
590 600 610 620 630
100 110 120 130 140
pF1KB6 RTHLLSRLPIPESQV----ITINPELPVEE--AAEDYAKKLRQAFQGDSIPVFDLLILGV
..:::... :: .. . .. .: .:: .:. ::... ..: :::..::.
NP_004 QAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALVANSS---FDLVLLGM
640 650 660 670 680 690
150 160 170 180 190 200
pF1KB6 GPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRVTLTLPVLNAARTVIFVATGEGKA
: :::: ::::. : . :..:. .. ::. : .:..:.::..: :. : .. :. :
NP_004 GADGHTASLFPQSPTGLDGEQLVV-LTTSPSQPHRRMSLSLPLINRAKKVAVLVMGRMKR
700 710 720 730 740 750
210 220 230 240 250
pF1KB6 AVLKRILE-DQEENPLPAALVQPHTGKLCWFLDEAAARLLTVPFEKHSTL
. . . .: . : . : ::.:.: :..: :
NP_004 EITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDAFLG
760 770 780 790
>>XP_005263597 (OMIM: 138090,604931) PREDICTED: GDH/6PGL (800 aa)
initn: 291 init1: 174 opt: 354 Z-score: 399.6 bits: 83.2 E(85289): 1.6e-15
Smith-Waterman score: 354; 33.7% identity (62.6% similar) in 246 aa overlap (8-244:564-797)
10 20 30
pF1KB6 MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGA
:.:.. :.:: . ::. . .:. :
XP_005 QQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAW--SEELISKLANDI--EATAVRAVR
540 550 560 570 580
40 50 60 70 80 90
pF1KB6 R-ARFALGLSGGSLVSMLARELPAAVAPAG-PASLARWTLGFCDERLVPFDHAESTYGLY
: ..: :.::::: : ..: :.: : : :. : . ::: ::.. ::..
XP_005 RFGQFHLALSGGSSPVALFQQL--ATAHYGFP--WAHTHLWLVDERCVPLSDPESNFQGL
590 600 610 620 630 640
100 110 120 130 140
pF1KB6 RTHLLSRLPIPESQV----ITINPELPVEE--AAEDYAKKLRQAFQGDSIPVFDLLILGV
..:::... :: .. . .. .: .:: .:. ::... ..: :::..::.
XP_005 QAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALVANSS---FDLVLLGM
650 660 670 680 690 700
150 160 170 180 190 200
pF1KB6 GPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRVTLTLPVLNAARTVIFVATGEGKA
: :::: ::::. : . :..:. .. ::. : .:..:.::..: :. : .. :. :
XP_005 GADGHTASLFPQSPTGLDGEQLVV-LTTSPSQPHRRMSLSLPLINRAKKVAVLVMGRMKR
710 720 730 740 750 760
210 220 230 240 250
pF1KB6 AVLKRILE-DQEENPLPAALVQPHTGKLCWFLDEAAARLLTVPFEKHSTL
. . . .: . : . : ::.:.: :..: :
XP_005 EITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDAFLG
770 780 790 800
>>NP_001269516 (OMIM: 138090,604931) GDH/6PGL endoplasmi (802 aa)
initn: 291 init1: 174 opt: 354 Z-score: 399.6 bits: 83.2 E(85289): 1.6e-15
Smith-Waterman score: 354; 33.7% identity (62.6% similar) in 246 aa overlap (8-244:566-799)
10 20 30
pF1KB6 MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGA
:.:.. :.:: . ::. . .:. :
NP_001 QQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAW--SEELISKLANDI--EATAVRAVR
540 550 560 570 580 590
40 50 60 70 80 90
pF1KB6 R-ARFALGLSGGSLVSMLARELPAAVAPAG-PASLARWTLGFCDERLVPFDHAESTYGLY
: ..: :.::::: : ..: :.: : : :. : . ::: ::.. ::..
NP_001 RFGQFHLALSGGSSPVALFQQL--ATAHYGFP--WAHTHLWLVDERCVPLSDPESNFQGL
600 610 620 630 640
100 110 120 130 140
pF1KB6 RTHLLSRLPIPESQV----ITINPELPVEE--AAEDYAKKLRQAFQGDSIPVFDLLILGV
..:::... :: .. . .. .: .:: .:. ::... ..: :::..::.
NP_001 QAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALVANSS---FDLVLLGM
650 660 670 680 690 700
150 160 170 180 190 200
pF1KB6 GPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRVTLTLPVLNAARTVIFVATGEGKA
: :::: ::::. : . :..:. .. ::. : .:..:.::..: :. : .. :. :
NP_001 GADGHTASLFPQSPTGLDGEQLVV-LTTSPSQPHRRMSLSLPLINRAKKVAVLVMGRMKR
710 720 730 740 750 760
210 220 230 240 250
pF1KB6 AVLKRILE-DQEENPLPAALVQPHTGKLCWFLDEAAARLLTVPFEKHSTL
. . . .: . : . : ::.:.: :..: :
NP_001 EITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDAFLG
770 780 790 800
258 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 9 12:17:34 2016 done: Wed Nov 9 12:17:35 2016
Total Scan time: 8.000 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]