Result of FASTA (ccds) for
pFN21AB6488
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6488, 357 aa
1>>>pF1KB6488 357 - 357 aa - 357 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4502+/-0.000831; mu= 18.7104+/- 0.051
mean_var=136.4848+/-24.943, 0's: 0 Z-trim(113.3): 64 B-trim: 46 in 1/51
Lambda= 0.109782
statistics sampled from 13894 (13960) to 13894 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.429), width: 16
Scan time: 2.380
The best scores are: opt bits E(32554)
CCDS6328.1 NOV gene_id:4856|Hs108|chr8 ( 357) 2606 423.7 1.2e-118
CCDS5151.1 CTGF gene_id:1490|Hs108|chr6 ( 349) 1357 225.9 4.1e-59
CCDS6371.1 WISP1 gene_id:8840|Hs108|chr8 ( 367) 1021 172.7 4.4e-43
CCDS5098.1 WISP3 gene_id:8838|Hs108|chr6 ( 354) 820 140.8 1.6e-33
CCDS5097.1 WISP3 gene_id:8838|Hs108|chr6 ( 372) 820 140.9 1.7e-33
CCDS13336.1 WISP2 gene_id:8839|Hs108|chr20 ( 250) 795 136.7 2.1e-32
CCDS706.1 CYR61 gene_id:3491|Hs108|chr1 ( 381) 578 102.6 5.9e-22
>>CCDS6328.1 NOV gene_id:4856|Hs108|chr8 (357 aa)
initn: 2606 init1: 2606 opt: 2606 Z-score: 2243.8 bits: 423.7 E(32554): 1.2e-118
Smith-Waterman score: 2606; 99.7% identity (100.0% similar) in 357 aa overlap (1-357:1-357)
10 20 30 40 50 60
pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGQCPATPPTCAPGVRAVLDG
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
CCDS63 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGRCPATPPTCAPGVRAVLDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 CSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTAVEGDNCVFDGVIYRSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 CSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTAVEGDNCVFDGVIYRSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 EKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEEDS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 LGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 TRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 TRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGRC
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 CTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELELKTTRGKM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 CTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELELKTTRGKM
310 320 330 340 350
>>CCDS5151.1 CTGF gene_id:1490|Hs108|chr6 (349 aa)
initn: 1352 init1: 910 opt: 1357 Z-score: 1174.8 bits: 225.9 E(32554): 4.1e-59
Smith-Waterman score: 1357; 51.5% identity (74.6% similar) in 338 aa overlap (21-357:15-348)
10 20 30 40 50
pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGQCPATP-PTCAPGVRAVLD
.:: : .. :. : : : .:: : : : :: :::
CCDS51 MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPC--RCPDEPAPRCPAGVSLVLD
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 GCSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTAVEGDNCVFDGVIYRS
::.:: :::.: :: :.. .::: .::.: .. . . :.::: .: :.: :..:::
CCDS51 GCGCCRVCAKQLGELCTERDPCDPHKGLFCHFGSPANRKIGVCTAKDGAPCIFGGTVYRS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 GEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEED
::.:: :::.:::: :: .::.: :..:: :: :.:: ::.:..::.:::.:.: ...
CCDS51 GESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 SLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLK
.. : .::::: : :.: . . .::. :::::.::::.::::.:::::: : .:.. :
CCDS51 TVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 QTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGR
:.::::::::: . :. ::::::.:: : : :......:::..::. .:::::.:::
CCDS51 QSRLCMVRPCEADLEENI-KKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGR
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 CCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELELKTTRGKM
::::: : :. .::.: :...:: .: : ::.:: ::: .:. : . : . : :
CCDS51 CCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIF-ESLYYRKMYGDMA
300 310 320 330 340
>>CCDS6371.1 WISP1 gene_id:8840|Hs108|chr8 (367 aa)
initn: 688 init1: 293 opt: 1021 Z-score: 887.0 bits: 172.7 E(32554): 4.4e-43
Smith-Waterman score: 1021; 43.1% identity (65.8% similar) in 313 aa overlap (37-344:46-353)
10 20 30 40 50 60
pF1KB6 TSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQ-C--PGQCPATPPTCAPGVRAVLDGCSC
:: : : .:: .:: : :: . ::: :
CCDS63 AASTVLATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPPRCPLGVSLITDGCEC
20 30 40 50 60 70
70 80 90 100 110 120
pF1KB6 CLVCARQRGESCSDLEPCDESSGLYCDRSAD-PSNQTGICTAVEGDNCVFDGVIYRSGEK
: .::.: :..:.. :: ::::: :.: : :.:. : : .::.::: : .:..
CCDS63 CKMCAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVCAQVVGVGCVLDGVRYNNGQS
80 90 100 110 120 130
130 140 150 160 170 180
pF1KB6 FQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEEDSLG
:::.::..::: :: .::.: : : : :. :: ::.: .::.:::.:.: :.:.
CCDS63 FQPNCKYNCTCIDGAVGCTPLC-LRVRPPRLWCPHPRRVSIPGHCCEQWVC---EDDAKR
140 150 160 170 180 190
190 200 210 220 230 240
pF1KB6 GLTLAAYRPEATLGV-EVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQT
: : .: :: ::: :. :. :: :::.: :::..: : :: ...
CCDS63 PRKTAPRDTGAFDAVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQES
200 210 220 230 240 250
250 260 270 280 290 300
pF1KB6 RLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGRCC
::: .:::. . . : ::::: . . .... . .: : ..:.:..:::: :.:::
CCDS63 RLCNLRPCDVDI-HTLIKAGKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCC
260 270 280 290 300 310
310 320 330 340 350
pF1KB6 TPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELELKTTRGKM
:...:::.. ::: : .. :. :..: :. .: . :. :
CCDS63 IPYKSKTIDVSFQCPDGLGFSRQVLWINACFCNLSCRNPNDIFADLESYPDFSEIAN
320 330 340 350 360
>>CCDS5098.1 WISP3 gene_id:8838|Hs108|chr6 (354 aa)
initn: 870 init1: 254 opt: 820 Z-score: 715.1 bits: 140.8 E(32554): 1.6e-33
Smith-Waterman score: 821; 37.2% identity (62.8% similar) in 336 aa overlap (27-350:36-353)
10 20 30 40 50
pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVA-ATQR---CPPQCPGQCPATPPTCAP
:.:. : :: : : .:: : : :
CCDS50 FSTLLLAGLAQFCCRVQGTGPLDTTPEGRPGEVSDAPQRKQFCHWPC--KCPQQKPRCPP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 GVRAVLDGCSCCLVCARQRGESCSDLEPCDESSGLYCDRSAD-PSNQTGICTAVEGDNCV
:: : :::.:: .::.: :: :.. . :: .::::: :.: : .::.:. . . .:
CCDS50 GVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRPRYETGVCAYLVAVGCE
70 80 90 100 110 120
120 130 140 150 160
pF1KB6 FDGVIYRSGEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPE---PNCPAPRKVEVPGECC
:. : :..:. :::. :.: : .: :::.: ...:. .: . . :.
CCDS50 FNQVHYHNGQVFQPNPLFSCLCVSGAIGCTP-----LFIPKLAGSHCSGAKG----GKKS
130 140 150 160 170
170 180 190 200 210 220
pF1KB6 EKWICGPD---EEDSLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFS
.. :. . .. : . :. ::: . . .:. :.:.:: ::..::::.:
CCDS50 DQSNCSLEPLLQQLSTSYKTMPAYRNLPLIWKK------KCLVQATKWTPCSRTCGMGIS
180 190 200 210 220
230 240 250 260 270 280
pF1KB6 TRVTNRNRQCEMLKQTRLCMVRPCEQEPEQPTD-KKGKKCLRTKKSLKAIHLQFKNCTSL
.::::.: .::: :. :::...::... . ::: : : . :: .. :..:.:
CCDS50 NRVTNENSNCEMRKEKRLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSST
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB6 HTYKPRFCGVCSDGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAF
..::: :::.: : ::: :...: : .:.: : .. : .:.:. :: . .. :
CCDS50 QSYKPTFCGICLDKRCCIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNCREPGDIF
290 300 310 320 330 340
350
pF1KB6 LQELELKTTRGKM
.::..
CCDS50 -SELKIL
350
>>CCDS5097.1 WISP3 gene_id:8838|Hs108|chr6 (372 aa)
initn: 870 init1: 254 opt: 820 Z-score: 714.9 bits: 140.9 E(32554): 1.7e-33
Smith-Waterman score: 821; 37.2% identity (62.8% similar) in 336 aa overlap (27-350:54-371)
10 20 30 40 50
pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVA-ATQR---CPPQCPGQCPATPPTCAP
:.:. : :: : : .:: : : :
CCDS50 FSTLLLAGLAQFCCRVQGTGPLDTTPEGRPGEVSDAPQRKQFCHWPC--KCPQQKPRCPP
30 40 50 60 70 80
60 70 80 90 100 110
pF1KB6 GVRAVLDGCSCCLVCARQRGESCSDLEPCDESSGLYCDRSAD-PSNQTGICTAVEGDNCV
:: : :::.:: .::.: :: :.. . :: .::::: :.: : .::.:. . . .:
CCDS50 GVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRPRYETGVCAYLVAVGCE
90 100 110 120 130 140
120 130 140 150 160
pF1KB6 FDGVIYRSGEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPE---PNCPAPRKVEVPGECC
:. : :..:. :::. :.: : .: :::.: ...:. .: . . :.
CCDS50 FNQVHYHNGQVFQPNPLFSCLCVSGAIGCTP-----LFIPKLAGSHCSGAKG----GKKS
150 160 170 180 190
170 180 190 200 210 220
pF1KB6 EKWICGPD---EEDSLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFS
.. :. . .. : . :. ::: . . .:. :.:.:: ::..::::.:
CCDS50 DQSNCSLEPLLQQLSTSYKTMPAYRNLPLIWKK------KCLVQATKWTPCSRTCGMGIS
200 210 220 230 240
230 240 250 260 270 280
pF1KB6 TRVTNRNRQCEMLKQTRLCMVRPCEQEPEQPTD-KKGKKCLRTKKSLKAIHLQFKNCTSL
.::::.: .::: :. :::...::... . ::: : : . :: .. :..:.:
CCDS50 NRVTNENSNCEMRKEKRLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSST
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB6 HTYKPRFCGVCSDGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAF
..::: :::.: : ::: :...: : .:.: : .. : .:.:. :: . .. :
CCDS50 QSYKPTFCGICLDKRCCIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNCREPGDIF
310 320 330 340 350 360
350
pF1KB6 LQELELKTTRGKM
.::..
CCDS50 -SELKIL
370
>>CCDS13336.1 WISP2 gene_id:8839|Hs108|chr20 (250 aa)
initn: 549 init1: 309 opt: 795 Z-score: 695.3 bits: 136.7 E(32554): 2.1e-32
Smith-Waterman score: 795; 47.2% identity (67.0% similar) in 233 aa overlap (18-249:10-237)
10 20 30 40 50 60
pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGQCPATPPTCAPGVRAVLDG
:.: :: ::..: :: :: : :: :: : :: ::::
CCDS13 MRGTPKTHLLAFSLLCLLSKVR-TQLCPTPCT--CPWPPPRCPLGVPLVLDG
10 20 30 40
70 80 90 100 110
pF1KB6 CSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTAVEGDN-CVFDGVIYRS
:.:: ::::. :: :..:. :: :.:: :. .: :... ..: .: :. : .: .::
CCDS13 CGCCRVCARRLGEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYRE
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 GEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEED
:: ::: :...: :.:: . ::: :. :: :: .:: ::.::: :.:: .:.:: .
CCDS13 GETFQPHCSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCG--QGG
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 SLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLK
.:: : : :. . : .: : : .: : :: .::.:..:::.:.:: :..
CCDS13 GLGTQPLPAQGPQFSGLVSSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLET
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 QTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGR
: :::. :::
CCDS13 QRRLCLSRPCPPSRGRSPQNSAF
230 240 250
>>CCDS706.1 CYR61 gene_id:3491|Hs108|chr1 (381 aa)
initn: 1155 init1: 345 opt: 578 Z-score: 507.6 bits: 102.6 E(32554): 5.9e-22
Smith-Waterman score: 1113; 44.2% identity (65.5% similar) in 362 aa overlap (16-343:9-365)
10 20 30 40 50 60
pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGQCPATPPTCAPGVRAVLDG
: :. :::: . .: :: : .:: : ::::: : ::
CCDS70 MSSRIARALALVVTLLHLTRLALST--CPAAC--HCPLEAPKCAPGVGLVRDG
10 20 30 40
70 80 90 100 110
pF1KB6 CSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTA-VEGDNCVFDGVIYRS
:.:: :::.: .:.:: .:::...:: :. .:. . ::: : :: : ... ::..
CCDS70 CGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQN
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 GEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPD---
::.:::.:: :::: :: .::.: : .. ::. .:: :: :.: :.:::.:.: :
CCDS70 GESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIK
110 120 130 140 150 160
180 190 200
pF1KB6 ----EEDSLGG--LTLAAYRPEATLGVEV----SDSSVN--------------------C
..:.: : : . : . : : . :. . ::.. :
CCDS70 DPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKC
170 180 190 200 210 220
210 220 230 240 250 260
pF1KB6 IEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQTRLCMVRPCEQEPEQPTDKKGKKCLR
: ::: :. :::.:: :.:::::: : .:...:.::.: :::: : : . :::::: .
CCDS70 IVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQ-PVYSSLKKGKKCSK
230 240 250 260 270 280
270 280 290 300 310 320
pF1KB6 TKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGRCCTPHNTKTIQAEFQCSPGQIVKKPVM
:::: . ... . .: :.. :.:..:: : :::::::. :.:.. .:.: :. .: ::
CCDS70 TKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVM
290 300 310 320 330 340
330 340 350
pF1KB6 VIGTCTCHTNCPKNNEAFLQELELKTTRGKM
.: .: :. :::. :::
CCDS70 MIQSCKCNYNCPHANEAAFPFYRLFNDIHKFRD
350 360 370 380
357 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 23:08:33 2016 done: Fri Nov 4 23:08:33 2016
Total Scan time: 2.380 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]