Result of FASTA (omim) for
pFN21AE0473
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0473, 197 aa
1>>>pF1KE0473 197 - 197 aa - 197 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.6519+/-0.000368; mu= 0.7779+/- 0.023
mean_var=235.5337+/-47.335, 0's: 0 Z-trim(121.8): 55 B-trim: 0 in 0/60
Lambda= 0.083569
statistics sampled from 38888 (38943) to 38888 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.768), E-opt: 0.2 (0.457), width: 16
Scan time: 6.040
The best scores are: opt bits E(85289)
XP_005257448 (OMIM: 160770) PREDICTED: myosin ligh ( 197) 1315 170.1 2e-42
NP_002467 (OMIM: 160770) myosin light chain 4 [Hom ( 197) 1315 170.1 2e-42
NP_001002841 (OMIM: 160770) myosin light chain 4 [ ( 197) 1315 170.1 2e-42
NP_000249 (OMIM: 160790,608751) myosin light chain ( 195) 1056 138.9 5e-33
XP_016880173 (OMIM: 160770) PREDICTED: myosin ligh ( 228) 938 124.8 1.1e-28
XP_016880172 (OMIM: 160770) PREDICTED: myosin ligh ( 228) 938 124.8 1.1e-28
XP_011523141 (OMIM: 160770) PREDICTED: myosin ligh ( 228) 938 124.8 1.1e-28
NP_524144 (OMIM: 160780) myosin light chain 1/3, s ( 194) 905 120.7 1.5e-27
NP_002466 (OMIM: 609930) myosin light chain 6B [Ho ( 208) 834 112.2 6e-25
NP_001186558 (OMIM: 609930) myosin light chain 6B ( 208) 834 112.2 6e-25
NP_066299 (OMIM: 609931) myosin light polypeptide ( 151) 790 106.7 1.9e-23
NP_524147 (OMIM: 609931) myosin light polypeptide ( 151) 761 103.2 2.1e-22
NP_524146 (OMIM: 160780) myosin light chain 1/3, s ( 150) 740 100.7 1.2e-21
NP_005176 (OMIM: 114184) calmodulin-like protein 3 ( 149) 364 55.4 5.3e-08
NP_001292553 (OMIM: 114182,616249) calmodulin isof ( 197) 366 55.7 5.5e-08
NP_008819 (OMIM: 114180,614916,616247) calmodulin ( 149) 360 54.9 7.5e-08
NP_001316851 (OMIM: 114183) calmodulin isoform 1 [ ( 149) 360 54.9 7.5e-08
NP_001734 (OMIM: 114182,616249) calmodulin isoform ( 149) 360 54.9 7.5e-08
NP_005175 (OMIM: 114183) calmodulin isoform 1 [Hom ( 149) 360 54.9 7.5e-08
XP_006720321 (OMIM: 114180,614916,616247) PREDICTE ( 150) 360 54.9 7.5e-08
NP_001316852 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 265 43.3 0.00017
NP_001316850 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 265 43.3 0.00017
NP_001292554 (OMIM: 114182,616249) calmodulin isof ( 113) 265 43.3 0.00017
NP_001316853 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 265 43.3 0.00017
NP_001316855 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 265 43.3 0.00017
NP_001316854 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 265 43.3 0.00017
NP_001292555 (OMIM: 114182,616249) calmodulin isof ( 113) 265 43.3 0.00017
NP_003270 (OMIM: 191039) troponin C, skeletal musc ( 160) 263 43.2 0.00026
XP_011527333 (OMIM: 191039) PREDICTED: troponin C, ( 145) 259 42.7 0.00034
NP_619650 (OMIM: 610171) calmodulin-like protein 6 ( 181) 243 40.9 0.0015
NP_001317242 (OMIM: 610171) calmodulin-like protei ( 164) 242 40.7 0.0015
XP_005244786 (OMIM: 610171) PREDICTED: calmodulin- ( 203) 243 40.9 0.0016
NP_003271 (OMIM: 191040,611879,613243) troponin C, ( 161) 239 40.3 0.0019
NP_004057 (OMIM: 603187) centrin-1 [Homo sapiens] ( 172) 224 38.6 0.0072
>>XP_005257448 (OMIM: 160770) PREDICTED: myosin light ch (197 aa)
initn: 1315 init1: 1315 opt: 1315 Z-score: 882.7 bits: 170.1 E(85289): 2e-42
Smith-Waterman score: 1315; 100.0% identity (100.0% similar) in 197 aa overlap (1-197:1-197)
10 20 30 40 50 60
pF1KE0 MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIEEFKEAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIEEFKEAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMNVKMLDFETFLPIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMNVKMLDFETFLPIL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 QHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAGQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAGQED
130 140 150 160 170 180
190
pF1KE0 ANGCINYEAFVKHIMSG
:::::::::::::::::
XP_005 ANGCINYEAFVKHIMSG
190
>>NP_002467 (OMIM: 160770) myosin light chain 4 [Homo sa (197 aa)
initn: 1315 init1: 1315 opt: 1315 Z-score: 882.7 bits: 170.1 E(85289): 2e-42
Smith-Waterman score: 1315; 100.0% identity (100.0% similar) in 197 aa overlap (1-197:1-197)
10 20 30 40 50 60
pF1KE0 MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIEEFKEAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIEEFKEAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMNVKMLDFETFLPIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMNVKMLDFETFLPIL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 QHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAGQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAGQED
130 140 150 160 170 180
190
pF1KE0 ANGCINYEAFVKHIMSG
:::::::::::::::::
NP_002 ANGCINYEAFVKHIMSG
190
>>NP_001002841 (OMIM: 160770) myosin light chain 4 [Homo (197 aa)
initn: 1315 init1: 1315 opt: 1315 Z-score: 882.7 bits: 170.1 E(85289): 2e-42
Smith-Waterman score: 1315; 100.0% identity (100.0% similar) in 197 aa overlap (1-197:1-197)
10 20 30 40 50 60
pF1KE0 MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIEEFKEAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIEEFKEAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMNVKMLDFETFLPIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMNVKMLDFETFLPIL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 QHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAGQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAGQED
130 140 150 160 170 180
190
pF1KE0 ANGCINYEAFVKHIMSG
:::::::::::::::::
NP_001 ANGCINYEAFVKHIMSG
190
>>NP_000249 (OMIM: 160790,608751) myosin light chain 3 [ (195 aa)
initn: 987 init1: 987 opt: 1056 Z-score: 714.0 bits: 138.9 E(85289): 5e-33
Smith-Waterman score: 1056; 80.6% identity (90.8% similar) in 196 aa overlap (1-196:1-194)
10 20 30 40 50 60
pF1KE0 MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIEEFKEAF
::::::::::. :: :: :::::: : : :: ::: :: ...::.:: .:::::::::
NP_000 MAPKKPEPKKDDAKAAPKAAPAPAP-P-PEPERPKEVEFDASKIKIEFTPEQIEEFKEAF
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 SLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMNVKMLDFETFLPIL
:::::: :::::::::::::::::::::.::::::::::. ::.:.::.:::::::.:
NP_000 MLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPML
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 QHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAGQED
::::.::. ::::::::::::::::.::::::::::::::::::..:: :::.:.:::::
NP_000 QHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQED
120 130 140 150 160 170
190
pF1KE0 ANGCINYEAFVKHIMSG
.:::::::::::::::
NP_000 SNGCINYEAFVKHIMSS
180 190
>>XP_016880173 (OMIM: 160770) PREDICTED: myosin light ch (228 aa)
initn: 1301 init1: 938 opt: 938 Z-score: 636.2 bits: 124.8 E(85289): 1.1e-28
Smith-Waterman score: 1243; 86.4% identity (86.4% similar) in 228 aa overlap (1-197:1-228)
10 20 30 40 50
pF1KE0 MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIE------
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIEGEYGQP
10 20 30 40 50 60
60 70 80
pF1KE0 -------------------------EFKEAFSLFDRTPTGEMKITYGQCGDVLRALGQNP
:::::::::::::::::::::::::::::::::::
XP_016 HLSVSIALSWRRRRRRKKRRSSCPHEFKEAFSLFDRTPTGEMKITYGQCGDVLRALGQNP
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE0 TNAEVLRVLGKPKPEEMNVKMLDFETFLPILQHISRNKEQGTYEDFVEGLRVFDKESNGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNAEVLRVLGKPKPEEMNVKMLDFETFLPILQHISRNKEQGTYEDFVEGLRVFDKESNGT
130 140 150 160 170 180
150 160 170 180 190
pF1KE0 VMGAELRHVLATLGEKMTEAEVEQLLAGQEDANGCINYEAFVKHIMSG
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMGAELRHVLATLGEKMTEAEVEQLLAGQEDANGCINYEAFVKHIMSG
190 200 210 220
>>XP_016880172 (OMIM: 160770) PREDICTED: myosin light ch (228 aa)
initn: 1301 init1: 938 opt: 938 Z-score: 636.2 bits: 124.8 E(85289): 1.1e-28
Smith-Waterman score: 1243; 86.4% identity (86.4% similar) in 228 aa overlap (1-197:1-228)
10 20 30 40 50
pF1KE0 MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIE------
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIEGEYGQP
10 20 30 40 50 60
60 70 80
pF1KE0 -------------------------EFKEAFSLFDRTPTGEMKITYGQCGDVLRALGQNP
:::::::::::::::::::::::::::::::::::
XP_016 HLSVSIALSWRRRRRRKKRRSSCPHEFKEAFSLFDRTPTGEMKITYGQCGDVLRALGQNP
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE0 TNAEVLRVLGKPKPEEMNVKMLDFETFLPILQHISRNKEQGTYEDFVEGLRVFDKESNGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNAEVLRVLGKPKPEEMNVKMLDFETFLPILQHISRNKEQGTYEDFVEGLRVFDKESNGT
130 140 150 160 170 180
150 160 170 180 190
pF1KE0 VMGAELRHVLATLGEKMTEAEVEQLLAGQEDANGCINYEAFVKHIMSG
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMGAELRHVLATLGEKMTEAEVEQLLAGQEDANGCINYEAFVKHIMSG
190 200 210 220
>>XP_011523141 (OMIM: 160770) PREDICTED: myosin light ch (228 aa)
initn: 1301 init1: 938 opt: 938 Z-score: 636.2 bits: 124.8 E(85289): 1.1e-28
Smith-Waterman score: 1243; 86.4% identity (86.4% similar) in 228 aa overlap (1-197:1-228)
10 20 30 40 50
pF1KE0 MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIE------
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIEGEYGQP
10 20 30 40 50 60
60 70 80
pF1KE0 -------------------------EFKEAFSLFDRTPTGEMKITYGQCGDVLRALGQNP
:::::::::::::::::::::::::::::::::::
XP_011 HLSVSIALSWRRRRRRKKRRSSCPHEFKEAFSLFDRTPTGEMKITYGQCGDVLRALGQNP
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE0 TNAEVLRVLGKPKPEEMNVKMLDFETFLPILQHISRNKEQGTYEDFVEGLRVFDKESNGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNAEVLRVLGKPKPEEMNVKMLDFETFLPILQHISRNKEQGTYEDFVEGLRVFDKESNGT
130 140 150 160 170 180
150 160 170 180 190
pF1KE0 VMGAELRHVLATLGEKMTEAEVEQLLAGQEDANGCINYEAFVKHIMSG
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMGAELRHVLATLGEKMTEAEVEQLLAGQEDANGCINYEAFVKHIMSG
190 200 210 220
>>NP_524144 (OMIM: 160780) myosin light chain 1/3, skele (194 aa)
initn: 721 init1: 721 opt: 905 Z-score: 615.6 bits: 120.7 E(85289): 1.5e-27
Smith-Waterman score: 905; 71.9% identity (85.2% similar) in 196 aa overlap (1-196:1-193)
10 20 30 40 50 60
pF1KE0 MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIEEFKEAF
::::: . :: .: : :::::::::::::: ::: .: ...::.:. .: .::::::
NP_524 MAPKK-DVKKPVAAAAAAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAF
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 SLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMNVKMLDFETFLPIL
:::: ::. ::: .: :::::::: ::::::: .:::.:. ::.:.: ..:: :::..
NP_524 LLFDR--TGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 QHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAGQED
: :: ::.:.:::::::::::::::.:::::::::::::::::::: : ::: :.:::::
NP_524 QAISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQED
120 130 140 150 160 170
190
pF1KE0 ANGCINYEAFVKHIMSG
.:::::::::::::::
NP_524 SNGCINYEAFVKHIMSI
180 190
>>NP_002466 (OMIM: 609930) myosin light chain 6B [Homo s (208 aa)
initn: 982 init1: 649 opt: 834 Z-score: 568.9 bits: 112.2 E(85289): 6e-25
Smith-Waterman score: 834; 65.8% identity (83.4% similar) in 199 aa overlap (3-196:12-207)
10 20 30 40
pF1KE0 MAPKKPEPKKEAAKPAPAPAPAPAPAPA-PA-PEAPK---EPAFDPKSVKI
: : .: ::::: : :: :: . : :: :.::. :: : ..: :
NP_002 MPPKKDVPVKKPAGPSISKPAAKPAAAGAP-PAKTKAEPAVPQAPQKTQEPPVDLSKVVI
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 DFTADQIEEFKEAFSLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEM
.:. ::.::::::: ::::. :. :: :.:::::.:::::::::::::.:::.:: .:.
NP_002 EFNKDQLEEFKEAFELFDRV--GDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEL
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE0 NVKMLDFETFLPILQHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKM
. . .:::::::.:: ...:. ::::::..::.::::::.:: ::::::::::.::::::
NP_002 KSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKM
120 130 140 150 160 170
170 180 190
pF1KE0 TEAEVEQLLAGQEDANGCINYEAFVKHIMSG
:: ::: .:::.::.:::::::::.:::.:
NP_002 TEEEVETVLAGHEDSNGCINYEAFLKHILSV
180 190 200
>>NP_001186558 (OMIM: 609930) myosin light chain 6B [Hom (208 aa)
initn: 982 init1: 649 opt: 834 Z-score: 568.9 bits: 112.2 E(85289): 6e-25
Smith-Waterman score: 834; 65.8% identity (83.4% similar) in 199 aa overlap (3-196:12-207)
10 20 30 40
pF1KE0 MAPKKPEPKKEAAKPAPAPAPAPAPAPA-PA-PEAPK---EPAFDPKSVKI
: : .: ::::: : :: :: . : :: :.::. :: : ..: :
NP_001 MPPKKDVPVKKPAGPSISKPAAKPAAAGAP-PAKTKAEPAVPQAPQKTQEPPVDLSKVVI
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 DFTADQIEEFKEAFSLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEM
.:. ::.::::::: ::::. :. :: :.:::::.:::::::::::::.:::.:: .:.
NP_001 EFNKDQLEEFKEAFELFDRV--GDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEL
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE0 NVKMLDFETFLPILQHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKM
. . .:::::::.:: ...:. ::::::..::.::::::.:: ::::::::::.::::::
NP_001 KSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKM
120 130 140 150 160 170
170 180 190
pF1KE0 TEAEVEQLLAGQEDANGCINYEAFVKHIMSG
:: ::: .:::.::.:::::::::.:::.:
NP_001 TEEEVETVLAGHEDSNGCINYEAFLKHILSV
180 190 200
197 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 06:01:43 2016 done: Thu Nov 3 06:01:44 2016
Total Scan time: 6.040 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]