Result of FASTA (omim) for
pFN21AB7665
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7665, 337 aa
1>>>pF1KB7665 337 - 337 aa - 337 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.3783+/-0.000384; mu= 2.3411+/- 0.024
mean_var=180.9146+/-37.397, 0's: 0 Z-trim(119.0): 60 B-trim: 294 in 1/56
Lambda= 0.095354
statistics sampled from 32485 (32559) to 32485 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.733), E-opt: 0.2 (0.382), width: 16
Scan time: 9.220
The best scores are: opt bits E(85289)
NP_036391 (OMIM: 604674) hairy/enhancer-of-split r ( 337) 2193 313.7 3.7e-85
XP_016866118 (OMIM: 604674) PREDICTED: hairy/enhan ( 291) 1903 273.7 3.3e-73
XP_016866117 (OMIM: 604674) PREDICTED: hairy/enhan ( 291) 1903 273.7 3.3e-73
XP_016866116 (OMIM: 604674) PREDICTED: hairy/enhan ( 291) 1903 273.7 3.3e-73
NP_036390 (OMIM: 602953) hairy/enhancer-of-split r ( 304) 858 130.0 6.5e-30
NP_001035798 (OMIM: 602953) hairy/enhancer-of-spli ( 308) 840 127.5 3.6e-29
NP_055386 (OMIM: 609034) hairy/enhancer-of-split r ( 328) 752 115.4 1.7e-25
XP_005270802 (OMIM: 609034) PREDICTED: hairy/enhan ( 300) 683 105.9 1.1e-22
NP_001269780 (OMIM: 602953) hairy/enhancer-of-spli ( 214) 400 66.9 4.5e-11
NP_005515 (OMIM: 139605) transcription factor HES- ( 280) 335 58.0 2.8e-08
NP_066993 (OMIM: 608060) transcription factor HES- ( 221) 290 51.8 1.7e-06
NP_001135939 (OMIM: 608060) transcription factor H ( 247) 282 50.7 3.9e-06
NP_061115 (OMIM: 610331) transcription cofactor HE ( 224) 210 40.8 0.0035
NP_001136325 (OMIM: 610331) transcription cofactor ( 222) 205 40.1 0.0055
NP_115969 (OMIM: 608059,613686) transcription fact ( 225) 201 39.5 0.0082
NP_061962 (OMIM: 609970) transcription factor HES- ( 173) 197 38.9 0.0097
>>NP_036391 (OMIM: 604674) hairy/enhancer-of-split relat (337 aa)
initn: 2193 init1: 2193 opt: 2193 Z-score: 1649.9 bits: 313.7 E(85289): 3.7e-85
Smith-Waterman score: 2193; 100.0% identity (100.0% similar) in 337 aa overlap (1-337:1-337)
10 20 30 40 50 60
pF1KB7 MKRPCEETTSESDMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MKRPCEETTSESDMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 RDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 FMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 HPHHWAAAFHHLPAALLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 HPHHWAAAFHHLPAALLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 PSTGSVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PSTGSVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAA
250 260 270 280 290 300
310 320 330
pF1KB7 TAISPPLSVSATSSPQQTSSGTNNKPYRPWGTEVGAF
:::::::::::::::::::::::::::::::::::::
NP_036 TAISPPLSVSATSSPQQTSSGTNNKPYRPWGTEVGAF
310 320 330
>>XP_016866118 (OMIM: 604674) PREDICTED: hairy/enhancer- (291 aa)
initn: 1903 init1: 1903 opt: 1903 Z-score: 1435.3 bits: 273.7 E(85289): 3.3e-73
Smith-Waterman score: 1903; 100.0% identity (100.0% similar) in 291 aa overlap (47-337:1-291)
20 30 40 50 60 70
pF1KB7 TIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKRRRDRINNSLSELRRLVP
::::::::::::::::::::::::::::::
XP_016 MARKKRRGIIEKRRRDRINNSLSELRRLVP
10 20 30
80 90 100 110 120 130
pF1KB7 TAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARY
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB7 LSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPLHPHHWAAAFHHLPAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPLHPHHWAAAFHHLPAAL
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB7 LQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRMPSTGSVAPCVPPLSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRMPSTGSVAPCVPPLSTS
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB7 LLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAATAISPPLSVSATSSPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAATAISPPLSVSATSSPQ
220 230 240 250 260 270
320 330
pF1KB7 QTSSGTNNKPYRPWGTEVGAF
:::::::::::::::::::::
XP_016 QTSSGTNNKPYRPWGTEVGAF
280 290
>>XP_016866117 (OMIM: 604674) PREDICTED: hairy/enhancer- (291 aa)
initn: 1903 init1: 1903 opt: 1903 Z-score: 1435.3 bits: 273.7 E(85289): 3.3e-73
Smith-Waterman score: 1903; 100.0% identity (100.0% similar) in 291 aa overlap (47-337:1-291)
20 30 40 50 60 70
pF1KB7 TIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKRRRDRINNSLSELRRLVP
::::::::::::::::::::::::::::::
XP_016 MARKKRRGIIEKRRRDRINNSLSELRRLVP
10 20 30
80 90 100 110 120 130
pF1KB7 TAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARY
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB7 LSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPLHPHHWAAAFHHLPAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPLHPHHWAAAFHHLPAAL
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB7 LQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRMPSTGSVAPCVPPLSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRMPSTGSVAPCVPPLSTS
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB7 LLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAATAISPPLSVSATSSPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAATAISPPLSVSATSSPQ
220 230 240 250 260 270
320 330
pF1KB7 QTSSGTNNKPYRPWGTEVGAF
:::::::::::::::::::::
XP_016 QTSSGTNNKPYRPWGTEVGAF
280 290
>>XP_016866116 (OMIM: 604674) PREDICTED: hairy/enhancer- (291 aa)
initn: 1903 init1: 1903 opt: 1903 Z-score: 1435.3 bits: 273.7 E(85289): 3.3e-73
Smith-Waterman score: 1903; 100.0% identity (100.0% similar) in 291 aa overlap (47-337:1-291)
20 30 40 50 60 70
pF1KB7 TIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKRRRDRINNSLSELRRLVP
::::::::::::::::::::::::::::::
XP_016 MARKKRRGIIEKRRRDRINNSLSELRRLVP
10 20 30
80 90 100 110 120 130
pF1KB7 TAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARY
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB7 LSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPLHPHHWAAAFHHLPAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHPLHPHHWAAAFHHLPAAL
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB7 LQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRMPSTGSVAPCVPPLSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRMPSTGSVAPCVPPLSTS
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB7 LLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAATAISPPLSVSATSSPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAAAVAAATAISPPLSVSATSSPQ
220 230 240 250 260 270
320 330
pF1KB7 QTSSGTNNKPYRPWGTEVGAF
:::::::::::::::::::::
XP_016 QTSSGTNNKPYRPWGTEVGAF
280 290
>>NP_036390 (OMIM: 602953) hairy/enhancer-of-split relat (304 aa)
initn: 899 init1: 798 opt: 858 Z-score: 658.1 bits: 130.0 E(85289): 6.5e-30
Smith-Waterman score: 999; 54.7% identity (72.8% similar) in 342 aa overlap (1-337:1-304)
10 20 30 40 50
pF1KB7 MKRPCEE-TTSESDMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKR
::: : ..:.:..::::.: .:. . . ::.. ::::.:::.:::.::::::::
NP_036 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 RRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAM
:::::::::::::::::.::::::::::::::::::::::::::...:::::::::::::
NP_036 RRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 DFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHHHHP
:. :.::::::.::::::: .::::.::::::::::::.. :.::::: : ::
NP_036 DYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAA----SGAHAGLG
130 140 150 160 170
180 190 200 210 220 230
pF1KB7 LHPHHWAAAFHHLPAA---LLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADS
: :...: : : :: :.. :.. .: :.: . : : . : .: : ..
NP_036 HIP--WGTVFGHHPHIAHPLLLPQNGHGNAGT-----TASPTEPHHQGRLGSA---HPEA
180 190 200 210 220
240 250 260 270 280 290
pF1KB7 -ALRMPSTGSVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPNAAA
::: : .::..: : :. :: .:: . ...:. .: ::.:: :.: .: :::
NP_036 PALRAPPSGSLGP-VLPVVTSASKLSPPLLSSVASLSA----FPFSF-GSFHLLSPNA--
230 240 250 260 270
300 310 320 330
pF1KB7 AVAAATAISPPLSVSATSSPQQTSSGTNNKPYRPWGTEVGAF
.:: :.: :... .:::::::::.:::
NP_036 -------LSP-------SAPTQAANL--GKPYRPWGTEIGAF
280 290 300
>>NP_001035798 (OMIM: 602953) hairy/enhancer-of-split re (308 aa)
initn: 589 init1: 488 opt: 840 Z-score: 644.6 bits: 127.5 E(85289): 3.6e-29
Smith-Waterman score: 981; 54.0% identity (72.0% similar) in 346 aa overlap (1-337:1-308)
10 20 30 40 50
pF1KB7 MKRPCEE-TTSESDMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKR
::: : ..:.:..::::.: .:. . . ::.. ::::.:::.:::.::::::::
NP_001 MKRAHPEYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 RRDRINNSLSELRRLVPTAFEKQ----GSAKLEKAEILQMTVDHLKMLQATGGKGYFDAH
:::::::::::::::::.::::: :::::::::::::::::::::...:::::::::
NP_001 RRDRINNSLSELRRLVPSAFEKQVMEQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAH
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 ALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAH
:::::. :.::::::.::::::: .::::.::::::::::::.. :.::::: : ::
NP_001 ALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAA----SGAH
130 140 150 160 170
180 190 200 210 220 230
pF1KB7 HHHPLHPHHWAAAFHHLPAA---LLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFA
: :...: : : :: :.. :.. .: :.: . : : . : .:
NP_001 AGLGHIP--WGTVFGHHPHIAHPLLLPQNGHGNAGT-----TASPTEPHHQGRLGSA---
180 190 200 210 220
240 250 260 270 280 290
pF1KB7 HADS-ALRMPSTGSVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPP
: .. ::: : .::..: : :. :: .:: . ...:. .: ::.:: :.: .: :
NP_001 HPEAPALRAPPSGSLGP-VLPVVTSASKLSPPLLSSVASLSA----FPFSF-GSFHLLSP
230 240 250 260 270 280
300 310 320 330
pF1KB7 NAAAAVAAATAISPPLSVSATSSPQQTSSGTNNKPYRPWGTEVGAF
:: .:: :.: :... .:::::::::.:::
NP_001 NA---------LSP-------SAPTQAANL--GKPYRPWGTEIGAF
290 300
>>NP_055386 (OMIM: 609034) hairy/enhancer-of-split relat (328 aa)
initn: 725 init1: 552 opt: 752 Z-score: 578.8 bits: 115.4 E(85289): 1.7e-25
Smith-Waterman score: 752; 46.1% identity (65.1% similar) in 347 aa overlap (1-337:1-328)
10 20 30 40 50 60
pF1KB7 MKRPCEETTSESDMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKRR
:::: : . :... : ::::.: :: .. . :..:.. ::..:::::::::::::
NP_055 MKRPKEPSGSDGESDGPIDVGQE----GQLSQMARPLSTPSS-SQMQARKKRRGIIEKRR
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 RDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMD
:::::.::::::::::::::::::.::::::.:::::::::::.:::: :.:::.:::.:
NP_055 RDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAVD
60 70 80 90 100 110
130 140 150 160 170
pF1KB7 FMSIGFRECLTEVARYLSSVEGLDS-SDPLRVRLVSHLSTCATQREAAAM-TSSMAHHHH
: ::::::::::: :::. .:: .: .::.:.::.:::.. :.. : . :. .:
NP_055 FRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAF---
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 PLHPHHWAAAFHHLPAALLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSAL
: : :. :: :. : : .: . : :: :: . .: ...
NP_055 PAWP--WSF-FHSCPGLPALSNQLAILGRVPSPVLPGVSSPAYPIPALRTAPLRRA-TGI
180 190 200 210 220
240 250 260 270 280 290
pF1KB7 RMPSTGSVAPCVPPLSTSL---LSLSATVHAAAAAATAA--AHSFPLSFAGAFPMLPPNA
.:. .: : :: : :: .: .. :: .: :: . .. : ::.
NP_055 ILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPL-LQSSSPT-PPGP
230 240 250 260 270 280
300 310 320 330
pF1KB7 AAAVAAATAISPPLSVSATSSPQQTSSGTNNKPYRPWG---TEVGAF
... :: .:. : : ::: .. .. :. : ::.:::
NP_055 TGS-AAYVAVPTPNS----SSPGPAGRPAGAMLYHSWVSEITEIGAF
290 300 310 320
>>XP_005270802 (OMIM: 609034) PREDICTED: hairy/enhancer- (300 aa)
initn: 653 init1: 545 opt: 683 Z-score: 528.0 bits: 105.9 E(85289): 1.1e-22
Smith-Waterman score: 683; 46.6% identity (65.6% similar) in 311 aa overlap (37-337:5-300)
10 20 30 40 50 60
pF1KB7 ETTSESDMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKRRRDRINN
:..:.. ::..::::.:::::::::::::.
XP_005 MARPLSTPSS-SQMQARKKHRGIIEKRRRDRINS
10 20 30
70 80 90 100 110 120
pF1KB7 SLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALAMDFMSIGF
::::::::::::::::::.::::::.:::::::::::.:::: :.:::.:::.:: ::::
XP_005 SLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAVDFRSIGF
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 RECLTEVARYLSSVEGLDS-SDPLRVRLVSHLSTCATQREAAAM-TSSMAHHHHPLHPHH
::::::: :::. .:: .: .::.:.::.:::.. :.. : . :. .: : :
XP_005 RECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAF---PAWP--
100 110 120 130 140
190 200 210 220 230 240
pF1KB7 WAAAFHHLPAALLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRMPSTG
:. :: :. : : .: . : :: :: . .: ... .:.
XP_005 WSF-FHSCPGLPALSNQLAILGRVPSPVLPGVSSPAYPIPALRTAPLRRA-TGIILPARR
150 160 170 180 190 200
250 260 270 280 290
pF1KB7 SVAPCVPPLSTSL---LSLSATVHAAAAAATAA--AHSFPLSFAGAFPMLPPNAAAAVAA
.: : :: : :: .: .. :: .: :: . .. : ::. ... ::
XP_005 NVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPL-LQSSSPT-PPGPTGS-AA
210 220 230 240 250 260
300 310 320 330
pF1KB7 ATAISPPLSVSATSSPQQTSSGTNNKPYRPWG---TEVGAF
.:. : : ::: .. .. :. : ::.:::
XP_005 YVAVPTPNS----SSPGPAGRPAGAMLYHSWVSEITEIGAF
270 280 290 300
>>NP_001269780 (OMIM: 602953) hairy/enhancer-of-split re (214 aa)
initn: 445 init1: 344 opt: 400 Z-score: 319.7 bits: 66.9 E(85289): 4.5e-11
Smith-Waterman score: 541; 44.7% identity (64.7% similar) in 255 aa overlap (87-337:3-214)
60 70 80 90 100 110
pF1KB7 EKRRRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHA
::. ... .. .: :: .:::::::
NP_001 MPLEERNVFWLSKGNL-----TGDQGYFDAHA
10 20
120 130 140 150 160 170
pF1KB7 LAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMAHH
::::. :.::::::.::::::: .::::.::::::::::::.. :.::::: : ::
NP_001 LAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAA----SGAHA
30 40 50 60 70 80
180 190 200 210 220 230
pF1KB7 HHPLHPHHWAAAFHHLPAA---LLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAH
: :...: : : :: :.. :.. .: :.: . : : . : .: :
NP_001 GLGHIP--WGTVFGHHPHIAHPLLLPQNGHGNAGT-----TASPTEPHHQGRLGSA---H
90 100 110 120 130
240 250 260 270 280 290
pF1KB7 ADS-ALRMPSTGSVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPN
.. ::: : .::..: : :. :: .:: . ...:. .: ::.:: :.: .: ::
NP_001 PEAPALRAPPSGSLGP-VLPVVTSASKLSPPLLSSVASLSA----FPFSF-GSFHLLSPN
140 150 160 170 180
300 310 320 330
pF1KB7 AAAAVAAATAISPPLSVSATSSPQQTSSGTNNKPYRPWGTEVGAF
: .:: :.: :... .:::::::::.:::
NP_001 A---------LSP-------SAPTQAAN--LGKPYRPWGTEIGAF
190 200 210
>>NP_005515 (OMIM: 139605) transcription factor HES-1 [H (280 aa)
initn: 322 init1: 157 opt: 335 Z-score: 269.7 bits: 58.0 E(85289): 2.8e-08
Smith-Waterman score: 354; 32.3% identity (56.0% similar) in 316 aa overlap (23-330:7-278)
10 20 30 40 50
pF1KB7 MKRPCEETTSESDMDETIDVGSENNYSGQSTSSVIRLNS----PTTTSQIMARKKRRGII
:.: :. ... .:. : :.:. ::. . :.
NP_005 MPADIMEKNSSSPVAATPASVNTTPDKPKTASE--HRKSSKPIM
10 20 30 40
60 70 80 90 100 110
pF1KB7 EKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQATGGKGYFDA
::::: :::.:::.:. :. :..:..: .:::::.::.::: ::. :: . . ...
NP_005 EKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALST
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 HALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMA
.. . :: ::..::.:.::. ::... .:.::..::..: :: :::
NP_005 DPSVLGKYRAGFSECMNEVTRFLSTCEGVNT--EVRTRLLGHLANCMTQ--INAMT----
110 120 130 140 150
180 190 200 210 220 230
pF1KB7 HHHHPLHPHHWAAAFHHLPAALLQPNG-LHASESTPCRLSTTSEVPPAHGSALLTATFAH
.: .:: :.. : :.: :: . : : :: :.:
NP_005 ---YPGQPH---PALQAPPPPPPGPGGPQHAPFAPPPPL-----VPIPGGAA--------
160 170 180 190
240 250 260 270 280 290
pF1KB7 ADSALRMPSTGSVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFA-GAFPMLPPN
: :. ::: :. : . .: : .. .. : .: . . ::: :
NP_005 -------PPPGG-APC--KLG-SQAGEAAKVFGGFQVVPAPDGQFAFLIPNGAFAHSGPV
200 210 220 230 240
300 310 320 330
pF1KB7 AAAAVAAATAISPPLSVSATSSPQQTSSGTNNKPYRPWGTEVGAF
. .. . . : .:: .:.: : : .. .:::
NP_005 IPVYTSNSGTSVGPNAVSPSSGP----SLTADSMWRPWRN
250 260 270 280
337 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 21:29:36 2016 done: Fri Nov 4 21:29:38 2016
Total Scan time: 9.220 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]