Result of FASTA (omim) for
pFN21AE5102
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5102, 147 aa
1>>>pF1KE5102 147 - 147 aa - 147 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1905+/-0.000316; mu= 11.3935+/- 0.020
mean_var=55.9611+/-10.926, 0's: 0 Z-trim(115.7): 17 B-trim: 0 in 0/53
Lambda= 0.171447
statistics sampled from 26267 (26284) to 26267 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.308), width: 16
Scan time: 4.780
The best scores are: opt bits E(85289)
NP_000509 (OMIM: 140700,141749,141900,603902,60390 ( 147) 991 252.8 1.4e-67
NP_000510 (OMIM: 142000) hemoglobin subunit delta ( 147) 929 237.5 5.9e-63
NP_005321 (OMIM: 142100) hemoglobin subunit epsilo ( 147) 774 199.2 2.1e-51
NP_000175 (OMIM: 141749,142250,613977) hemoglobin ( 147) 756 194.7 4.5e-50
NP_000550 (OMIM: 141749,142200) hemoglobin subunit ( 147) 745 192.0 3e-49
NP_000549 (OMIM: 140700,141800,604131,613978) hemo ( 142) 381 101.9 3.7e-22
NP_000508 (OMIM: 140700,141850,604131,613978) hemo ( 142) 381 101.9 3.7e-22
XP_005255345 (OMIM: 142310) PREDICTED: hemoglobin ( 142) 321 87.1 1.1e-17
NP_005323 (OMIM: 142310) hemoglobin subunit zeta [ ( 142) 321 87.1 1.1e-17
XP_005255344 (OMIM: 142310) PREDICTED: hemoglobin ( 154) 321 87.1 1.2e-17
NP_005322 (OMIM: 142240) hemoglobin subunit theta- ( 142) 316 85.9 2.5e-17
NP_001003938 (OMIM: 609639) hemoglobin subunit mu ( 141) 281 77.2 1e-14
NP_976311 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 163 48.0 6.7e-06
NP_976312 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 163 48.0 6.7e-06
XP_005261662 (OMIM: 160000) PREDICTED: myoglobin i ( 154) 163 48.0 6.7e-06
NP_005359 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 163 48.0 6.7e-06
NP_067080 (OMIM: 605304) neuroglobin [Homo sapiens ( 151) 129 39.6 0.0022
>>NP_000509 (OMIM: 140700,141749,141900,603902,603903,60 (147 aa)
initn: 991 init1: 991 opt: 991 Z-score: 1334.1 bits: 252.8 E(85289): 1.4e-67
Smith-Waterman score: 991; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE5 MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG
70 80 90 100 110 120
130 140
pF1KE5 KEFTPPVQAAYQKVVAGVANALAHKYH
:::::::::::::::::::::::::::
NP_000 KEFTPPVQAAYQKVVAGVANALAHKYH
130 140
>>NP_000510 (OMIM: 142000) hemoglobin subunit delta [Hom (147 aa)
initn: 929 init1: 929 opt: 929 Z-score: 1251.2 bits: 237.5 E(85289): 5.9e-63
Smith-Waterman score: 929; 93.2% identity (98.0% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE5 MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK
:::::::::.::.::::::::: :::::::::::::::::::::::::::.:::::::::
NP_000 MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG
::::::::::::::::::::::::::. ::::::::::::::::::::::::::::..::
NP_000 VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG
70 80 90 100 110 120
130 140
pF1KE5 KEFTPPVQAAYQKVVAGVANALAHKYH
::::: .::::::::::::::::::::
NP_000 KEFTPQMQAAYQKVVAGVANALAHKYH
130 140
>>NP_005321 (OMIM: 142100) hemoglobin subunit epsilon [H (147 aa)
initn: 774 init1: 774 opt: 774 Z-score: 1044.0 bits: 199.2 E(85289): 2.1e-51
Smith-Waterman score: 774; 75.5% identity (93.9% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE5 MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK
:::.: :::.:::.::.:.::.:.:::::::::::::::::::.:::.::.:.:..::::
NP_005 MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG
::::::::: .:.:.. ..:::: .:: ::::::::::::::::.:::::.: .:: :::
NP_005 VKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFG
70 80 90 100 110 120
130 140
pF1KE5 KEFTPPVQAAYQKVVAGVANALAHKYH
::::: ::::.::.:..:: :::::::
NP_005 KEFTPEVQAAWQKLVSAVAIALAHKYH
130 140
>>NP_000175 (OMIM: 141749,142250,613977) hemoglobin subu (147 aa)
initn: 756 init1: 756 opt: 756 Z-score: 1019.9 bits: 194.7 E(85289): 4.5e-50
Smith-Waterman score: 756; 73.5% identity (93.2% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE5 MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK
: :.: :.:...:.:::::::...:::.:::::::::::::::.:::.::. .:.:::::
NP_000 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG
::::::::: ...:.. :::.:::::: ::::::::::::::::.::::::: ::: :::
NP_000 VKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
70 80 90 100 110 120
130 140
pF1KE5 KEFTPPVQAAYQKVVAGVANALAHKYH
::::: :::..::.:.:::.::. .::
NP_000 KEFTPEVQASWQKMVTGVASALSSRYH
130 140
>>NP_000550 (OMIM: 141749,142200) hemoglobin subunit gam (147 aa)
initn: 745 init1: 745 opt: 745 Z-score: 1005.2 bits: 192.0 E(85289): 3e-49
Smith-Waterman score: 745; 72.8% identity (92.5% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE5 MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK
: :.: :.:...:.:::::::...:::.:::::::::::::::.:::.::. .:.:::::
NP_000 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG
::::::::: ...:. :::.:::::: ::::::::::::::::.::::::: ::: :::
NP_000 VKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
70 80 90 100 110 120
130 140
pF1KE5 KEFTPPVQAAYQKVVAGVANALAHKYH
::::: :::..::.:..::.::. .::
NP_000 KEFTPEVQASWQKMVTAVASALSSRYH
130 140
>>NP_000549 (OMIM: 140700,141800,604131,613978) hemoglob (142 aa)
initn: 325 init1: 273 opt: 381 Z-score: 518.9 bits: 101.9 E(85289): 3.7e-22
Smith-Waterman score: 381; 43.4% identity (74.5% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE5 MVHLTPEEKSAVTALWGKV--NVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGN
:.: .:. : : :::: .. : :.::: :... .: :. .: : ::: :.
NP_000 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF-DLS-----HGS
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 PKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHH
.::.::::: :.....::.:.. .....::.:: ::.::: ::.::.. :. .:: :
NP_000 AQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAH
60 70 80 90 100 110
120 130 140
pF1KE5 FGKEFTPPVQAAYQKVVAGVANALAHKYH
. :::: :.:. .: .:.:...:. ::
NP_000 LPAEFTPAVHASLDKFLASVSTVLTSKYR
120 130 140
>>NP_000508 (OMIM: 140700,141850,604131,613978) hemoglob (142 aa)
initn: 325 init1: 273 opt: 381 Z-score: 518.9 bits: 101.9 E(85289): 3.7e-22
Smith-Waterman score: 381; 43.4% identity (74.5% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE5 MVHLTPEEKSAVTALWGKV--NVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGN
:.: .:. : : :::: .. : :.::: :... .: :. .: : ::: :.
NP_000 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF-DLS-----HGS
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 PKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHH
.::.::::: :.....::.:.. .....::.:: ::.::: ::.::.. :. .:: :
NP_000 AQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAH
60 70 80 90 100 110
120 130 140
pF1KE5 FGKEFTPPVQAAYQKVVAGVANALAHKYH
. :::: :.:. .: .:.:...:. ::
NP_000 LPAEFTPAVHASLDKFLASVSTVLTSKYR
120 130 140
>>XP_005255345 (OMIM: 142310) PREDICTED: hemoglobin subu (142 aa)
initn: 231 init1: 231 opt: 321 Z-score: 438.7 bits: 87.1 E(85289): 1.1e-17
Smith-Waterman score: 321; 37.2% identity (73.1% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE5 MVHLTPEEKSAVTALWGKVNV--DEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGN
:: :.. ....:.:... : .: :.: ::.. .: :. .: : :: : :.
XP_005 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF-DLH-P----GS
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 PKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHH
...:::.::..: .:.. .:.. :... ::::: :.::: ::.::.. :. .:: .
XP_005 AQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAAR
60 70 80 90 100 110
120 130 140
pF1KE5 FGKEFTPPVQAAYQKVVAGVANALAHKYH
: .:: ..::..: .. :...:..::
XP_005 FPADFTAEAHAAWDKFLSVVSSVLTEKYR
120 130 140
>>NP_005323 (OMIM: 142310) hemoglobin subunit zeta [Homo (142 aa)
initn: 231 init1: 231 opt: 321 Z-score: 438.7 bits: 87.1 E(85289): 1.1e-17
Smith-Waterman score: 321; 37.2% identity (73.1% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE5 MVHLTPEEKSAVTALWGKVNV--DEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGN
:: :.. ....:.:... : .: :.: ::.. .: :. .: : :: : :.
NP_005 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF-DLH-P----GS
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 PKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHH
...:::.::..: .:.. .:.. :... ::::: :.::: ::.::.. :. .:: .
NP_005 AQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAAR
60 70 80 90 100 110
120 130 140
pF1KE5 FGKEFTPPVQAAYQKVVAGVANALAHKYH
: .:: ..::..: .. :...:..::
NP_005 FPADFTAEAHAAWDKFLSVVSSVLTEKYR
120 130 140
>>XP_005255344 (OMIM: 142310) PREDICTED: hemoglobin subu (154 aa)
initn: 231 init1: 231 opt: 321 Z-score: 438.1 bits: 87.1 E(85289): 1.2e-17
Smith-Waterman score: 321; 37.2% identity (73.1% similar) in 145 aa overlap (4-146:15-153)
10 20 30 40
pF1KE5 MVHLTPEEKSAVTALWGKVNV--DEVGGEALGRLLVVYPWTQRFFESFG
:: :.. ....:.:... : .: :.: ::.. .: :. .: :
XP_005 MTCFFDAAHPAAMSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF-
10 20 30 40 50
50 60 70 80 90 100
pF1KE5 DLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLL
:: : :. ...:::.::..: .:.. .:.. :... ::::: :.::: ::.::
XP_005 DLH-P----GSAQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLL
60 70 80 90 100 110
110 120 130 140
pF1KE5 GNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH
.. :. .:: .: .:: ..::..: .. :...:..::
XP_005 SHCLLVTLAARFPADFTAEAHAAWDKFLSVVSSVLTEKYR
120 130 140 150
147 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 21:05:39 2016 done: Mon Nov 7 21:05:39 2016
Total Scan time: 4.780 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]