Result of FASTA (omim) for
pFN21AB9728
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9728, 444 aa
1>>>pF1KB9728 444 - 444 aa - 444 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.1809+/-0.000331; mu= -2.1436+/- 0.021
mean_var=310.3040+/-62.977, 0's: 0 Z-trim(125.2): 133 B-trim: 110 in 1/56
Lambda= 0.072808
statistics sampled from 48440 (48577) to 48440 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.827), E-opt: 0.2 (0.57), width: 16
Scan time: 9.600
The best scores are: opt bits E(85289)
NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444) 3121 340.8 4.4e-93
NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 972 115.0 3.5e-25
NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 663 82.6 2.5e-15
NP_004463 (OMIM: 601091) forkhead box protein D1 [ ( 465) 620 78.1 5.5e-14
NP_036315 (OMIM: 607836,611539) forkhead box prote ( 478) 575 73.4 1.5e-12
NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373) 567 72.4 2.2e-12
NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 556 71.3 5.2e-12
NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 519 67.4 7.3e-11
NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 521 67.7 8.5e-11
NP_004109 (OMIM: 602939) forkhead box protein S1 [ ( 330) 507 66.1 1.6e-10
NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 505 66.0 2.2e-10
NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 500 65.4 2.8e-10
NP_036316 (OMIM: 611084) forkhead box protein D4-l ( 408) 500 65.4 3.1e-10
NP_005240 (OMIM: 164874,613454) forkhead box prote ( 489) 490 64.4 7.4e-10
NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 480 63.2 1.1e-09
NP_954714 (OMIM: 611085) forkhead box protein D4-l ( 416) 480 63.3 1.4e-09
NP_954586 (OMIM: 611086) forkhead box protein D4-l ( 417) 480 63.3 1.4e-09
XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 480 63.4 1.4e-09
NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 477 62.9 1.5e-09
NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 480 63.4 1.5e-09
NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 480 63.4 1.6e-09
NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 475 62.8 2.1e-09
NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 475 62.8 2.1e-09
NP_997188 (OMIM: 601092) forkhead box protein D4 [ ( 439) 472 62.5 2.5e-09
NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 425 57.5 6.9e-08
XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 421 57.3 1.3e-07
NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 421 57.3 1.5e-07
NP_003914 (OMIM: 603621) forkhead box protein H1 [ ( 365) 412 56.1 1.7e-07
NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 404 55.5 4.8e-07
XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 369 51.8 5.6e-06
NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 369 51.8 5.7e-06
XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596) 369 51.8 5.7e-06
XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607) 369 51.8 5.8e-06
NP_001185780 (OMIM: 616035) forkhead box protein J ( 622) 369 51.8 5.9e-06
NP_001185779 (OMIM: 616035) forkhead box protein J ( 622) 369 51.8 5.9e-06
NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622) 369 51.8 5.9e-06
XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622) 369 51.8 5.9e-06
XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630) 369 51.8 6e-06
NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 356 50.3 1.1e-05
NP_001230018 (OMIM: 602341) forkhead box protein M ( 747) 334 48.2 8.6e-05
NP_973732 (OMIM: 602341) forkhead box protein M1 i ( 748) 334 48.2 8.7e-05
NP_001230017 (OMIM: 602341) forkhead box protein M ( 748) 334 48.2 8.7e-05
XP_011519233 (OMIM: 602341) PREDICTED: forkhead bo ( 749) 334 48.2 8.7e-05
XP_011523671 (OMIM: 600838,601705) PREDICTED: fork ( 436) 319 46.4 0.00017
XP_011523670 (OMIM: 600838,601705) PREDICTED: fork ( 436) 319 46.4 0.00017
XP_011523672 (OMIM: 600838,601705) PREDICTED: fork ( 436) 319 46.4 0.00017
XP_011523669 (OMIM: 600838,601705) PREDICTED: fork ( 462) 319 46.5 0.00018
XP_005258103 (OMIM: 600838,601705) PREDICTED: fork ( 648) 319 46.6 0.00023
NP_003584 (OMIM: 600838,601705) forkhead box prote ( 648) 319 46.6 0.00023
XP_016880717 (OMIM: 600838,601705) PREDICTED: fork ( 648) 319 46.6 0.00023
>>NP_001443 (OMIM: 603250) forkhead box protein F2 [Homo (444 aa)
initn: 3121 init1: 3121 opt: 3121 Z-score: 1792.1 bits: 340.8 E(85289): 4.4e-93
Smith-Waterman score: 3121; 100.0% identity (100.0% similar) in 444 aa overlap (1-444:1-444)
10 20 30 40 50 60
pF1KB9 MTTEGGPPPAPLRRACSPVPGALQAALMSPPPAAAAAAAAAPETTSSSSSSSSASCASSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTTEGGPPPAPLRRACSPVPGALQAALMSPPPAAAAAAAAAPETTSSSSSSSSASCASSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 SSSNSASAPSAACKSAGGGGAGAGSGGAKKASSGLRRPEKPPYSYIALIVMAIQSSPSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSNSASAPSAACKSAGGGGAGAGSGGAKKASSGLRRPEKPPYSYIALIVMAIQSSPSKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 LTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPAS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 EFMFEEGSFRRRPRGFRRKCQALKPMYHRVVSGLGFGASLLPQGFDFQAPPSAPLGCHSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFMFEEGSFRRRPRGFRRKCQALKPMYHRVVSGLGFGASLLPQGFDFQAPPSAPLGCHSQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 GGYGGLDMMPAGYDAGAGAPSHAHPHHHHHHHVPHMSPNPGSTYMASCPVPAGPGGVGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGYGGLDMMPAGYDAGAGAPSHAHPHHHHHHHVPHMSPNPGSTYMASCPVPAGPGGVGAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 GGGGGGDYGPDSSSSPVPSSPAMASAIECHSPYTSPAAHWSSPGASPYLKQPPALTPSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGGGGGDYGPDSSSSPVPSSPAMASAIECHSPYTSPAAHWSSPGASPYLKQPPALTPSSN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 PAASAGLHSSMSSYSLEQSYLHQNAREDLSVGLPRYQHHSTPVCDRKDFVLNFNGISSFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAASAGLHSSMSSYSLEQSYLHQNAREDLSVGLPRYQHHSTPVCDRKDFVLNFNGISSFH
370 380 390 400 410 420
430 440
pF1KB9 PSASGSYYHHHHQSVCQDIKPCVM
::::::::::::::::::::::::
NP_001 PSASGSYYHHHHQSVCQDIKPCVM
430 440
>>NP_001442 (OMIM: 265380,601089) forkhead box protein F (379 aa)
initn: 1115 init1: 819 opt: 972 Z-score: 573.1 bits: 115.0 E(85289): 3.5e-25
Smith-Waterman score: 1300; 55.0% identity (72.4% similar) in 413 aa overlap (66-444:2-379)
40 50 60 70 80
pF1KB9 AAAAAAPETTSSSSSSSSASCASSSSSSNSASAPSAACKSAGGGGAGAGSGGA-------
.::: ::::.:.:.:::
NP_001 MSSAPEKQQPPHGGGGGGGGGGGAAMDPASS
10 20 30
90 100 110 120 130 140
pF1KB9 -----KKASSGLRRPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQG
::...:.::::::::::::::::::::::.:::::::::::::.:::::::.:::
NP_001 GPSKAKKTNAGIRRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQG
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB9 WKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQAL
100 110 120 130 140 150
210 220 230 240 250
pF1KB9 KPMYHRVVSGLGFGASLLPQGFDFQAPPSAPLGC--HSQGGYGGLDMM----PAGYDAGA
:::: ...::::. ::. . ::. .. :.: .: . ::: :: :.. : :
NP_001 KPMYS-MMNGLGFNH--LPDTYGFQGSAGG-LSCPPNSLALEGGLGMMNGHLPGNVD-GM
160 170 180 190 200
260 270 280 290 300 310
pF1KB9 GAPSHAHPHHHHHHHVPHMSPNPGSTYMASCPVPAGPGGVGAAGGGGGGDYGPDSSSSPV
. :::. :::. : : .::..: ::...:.: : .:: :
NP_001 ALPSHS---------VPHLPSNGGHSYMGGC------------GGAAAGEY-PHHDSS-V
210 220 230 240
320 330 340 350 360
pF1KB9 PSSPAMASA----IECHSPYTSPAAHWSSPGASP-------YLKQPPALTPSSNPAASAG
:.:: . .. .: :. :.. :: : :.:: :.:: : :.: ::::.
NP_001 PASPLLPTGAGGVMEPHAVYSGSAAAWP-PSASAALNSGASYIKQQP-LSPC-NPAANP-
250 260 270 280 290
370 380 390 400 410 420
pF1KB9 LHSSMSSYSLEQSYLHQNARE---DLSVGLPRYQHHSTPVCDRKDFVLNFNGI--SSFHP
: .:.:..:::: :::::... .:. :.:::. .: .::::.::..::.. ::.:
NP_001 LSGSLSTHSLEQPYLHQNSHNAPAELQ-GIPRYHSQSPSMCDRKEFVFSFNAMASSSMHS
300 310 320 330 340 350
430 440
pF1KB9 SASGSYYHHHHQSVCQDIKPCVM
...:::::. : . ::::::::
NP_001 AGGGSYYHQ--QVTYQDIKPCVM
360 370
>>NP_004465 (OMIM: 602211) forkhead box protein D2 [Homo (495 aa)
initn: 616 init1: 521 opt: 663 Z-score: 396.1 bits: 82.6 E(85289): 2.5e-15
Smith-Waterman score: 663; 37.7% identity (57.7% similar) in 366 aa overlap (5-355:36-386)
10 20 30
pF1KB9 MTTEGGPPPAPLRRACSPVPGALQAALMSPPPAA
:: :: :. .: . ::
NP_004 CCCEIMSSESSPAALSEADADIDVVGGGSGGGELPA---RSGPRAPRDVLPHGHEPPAEE
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 AAAAAAAPETTSSSSSSSSASCASSSSSSNSASAP---SAACKSAGGGGAGAGSGGAKKA
: : : : :.. :.. .: ... .:..: .:: ..:.: : : ::::
NP_004 AEADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPGAAAARGAAGPGPGPPSGGA---
70 80 90 100 110
100 110 120 130 140 150
pF1KB9 SSGLRRPE-KPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRH
. : : ::::::::::.::: .::.:::::::: .:...:::..: . .:.::.::
NP_004 --ATRSPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRH
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB9 NLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYHRV
:::::.::.:.:. : ::::.:::.:: : ::..::: :: . :.: : : : . .
NP_004 NLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKR--QPLPPPHPH-
180 190 200 210 220 230
220 230 240 250 260
pF1KB9 VSGLGFGASLLPQGFDFQAPPSAPL-GCHSQGGYG-GLDMMPAGYDAGAGAPS-HAHPHH
:: : . :.: : : . :.:: : . .: : .:. : :::
NP_004 --PHPHPELLLRGGAAAAGDPGAFLPGFAAYGAYGYGYGLALPAYGAPPPGPAPHPHPHP
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB9 HHHHHVPHMSPNPGSTYM----ASCPVPAGPGGVGAAGGGGGGDYGPDSSSSPVPSS---
: . . : . . :. : :. : . ::.:.. .: :.:.: :.
NP_004 HAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASVFAGAGSAPAPAPASGSGPGPGPAGL
300 310 320 330 340 350
330 340 350 360 370
pF1KB9 PAMASA-IECHSPYTSPAAHWSSPGASPYLKQPPALTPSSNPAASAGLHSSMSSYSLEQS
::. .: . : . . :: : :.:. : ::
NP_004 PAFLGAELGCAKAFY--AASLSPPAAGTAAGLPTALLRQGLKTDAGGGAGGGGAGAGQRP
360 370 380 390 400 410
380 390 400 410 420 430
pF1KB9 YLHQNAREDLSVGLPRYQHHSTPVCDRKDFVLNFNGISSFHPSASGSYYHHHHQSVCQDI
NP_004 SFSIDHIMGHGGGGAAPPGAGEGSPGPPFAAAAGPGGQAQVLAMLTAPALAPVAGHIRLS
420 430 440 450 460 470
>>NP_004463 (OMIM: 601091) forkhead box protein D1 [Homo (465 aa)
initn: 528 init1: 528 opt: 620 Z-score: 372.1 bits: 78.1 E(85289): 5.5e-14
Smith-Waterman score: 681; 40.4% identity (59.1% similar) in 369 aa overlap (58-383:83-448)
30 40 50 60 70 80
pF1KB9 MSPPPAAAAAAAAAPETTSSSSSSSSASCASSSSSSNSASAPSAACKSAGGGGAGAGSGG
...: . . :: :: .:::::.:.:.::
NP_004 RRRRRSYAGEDELEDLEEEEDDDDILLAPPAGGSPAPPGPAP-AAGAGAGGGGGGGGAGG
60 70 80 90 100 110
90 100 110 120 130 140
pF1KB9 AKKASSGLRRPE-KPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKN
. .:.:: . : ::::::::::.::: .::.:::::::: .:...:::..: . .:.:
NP_004 GGSAGSGAKNPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQN
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB9 SVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPM
:.:::::::.::.:.:. : ::::.:::.:: : ::..::: :: . :.:. : :
NP_004 SIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQ-PLLPPN
180 190 200 210 220 230
210 220 230 240 250
pF1KB9 YHRVVSGLGFGASLLPQGFDFQA-----PPSAPLGCHSQG-G-YG---GLDMMP-----A
. : : ::. . : : ::. : :. : : :: ::.. : :
NP_004 AAAAESLLLRGAGAAGGAGDPAAAAALFPPAPPPPPHAYGYGPYGCGYGLQLPPYAPPSA
240 250 260 270 280 290
260 270 280 290 300
pF1KB9 GYDAGAGAPSHA--HPHHHHHHHVPHMSPNP-GSTYMASCPVPAG---PGGVGA----AG
. :.:.: . : ::: :: . . : .. : : : :: . : ::
NP_004 LFAAAAAAAAAAAFHPHSPPPPPPPHGAAAELARTAFGYRPHPLGAALPGPLPASAAKAG
300 310 320 330 340 350
310 320 330 340
pF1KB9 GGG---------------GGDYGPDSSSSPVPSSPAMASAIECHSPYTSPAAHWSSPG--
: : ::. :: .... . .. : :.: :: ..: : :: :
NP_004 GPGASALARSPFSIESIIGGSLGPAAAAAAAAQAAAAAQASPSPSPVAAPPAPGSSGGGC
360 370 380 390 400 410
350 360 370 380 390 400
pF1KB9 ASPYLKQPPALTPSSNPAASAGLHSSMSSYSLEQSYLHQNAREDLSVGLPRYQHHSTPVC
:. : : : ::.:. ::.:: : . :::
NP_004 AAQAAVGPAAALTRSLVAAAAAAASSVSS-SAALGTLHQGTALSSVENFTARISNC
420 430 440 450 460
410 420 430 440
pF1KB9 DRKDFVLNFNGISSFHPSASGSYYHHHHQSVCQDIKPCVM
>>NP_036315 (OMIM: 607836,611539) forkhead box protein D (478 aa)
initn: 558 init1: 504 opt: 575 Z-score: 346.4 bits: 73.4 E(85289): 1.5e-12
Smith-Waterman score: 603; 33.4% identity (58.7% similar) in 395 aa overlap (3-381:46-417)
10 20 30
pF1KB9 MTTEGGPPPAPLRRACSPVPGALQAALMSPP-
. .::: : .: :.: . . .::
NP_036 TVLTAEDVDIDVVGEGDDGLEEKDSDAGCDSPAGPPELRLDEADEVPPAAPHHGQPQPPH
20 30 40 50 60 70
40 50 60 70 80
pF1KB9 ------PAAAAAAAAAPETTSSSSSSSSASCASSSSSSNSASAPSAACKSAGGGGAGAGS
: ::.:.:.: .. .. . .: .. .. .... :.:: :::.::
NP_036 QQPLTLPKEAAGAGAGP--GGDVGAPEADGCKGGVGGEEGGA-------SGGGPGAGSGS
80 90 100 110 120
90 100 110 120 130 140
pF1KB9 GGAKKASSGLRRPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWK
.:. :. ::::::::::.::: .::.:.:::: : .:.. :::..: . .:.
NP_036 AGGLAPSKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQ
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB9 NSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQA-LK
::.:::::::.::.:.:. : ::::.:::.:: :: ::..::: :: . :.:. : :.
NP_036 NSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRHQQEHLR
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB9 PMYHRVVSGLGFGASLLPQGFDFQAPPSAPLGCHSQGGYGGLDMMPAGYDAGAGAPSHAH
. ... .::: : . .: . : : : .. :. . ::. :.:.: . .
NP_036 EQTALMMQ--SFGAYSLAAAAGAAGPYGRPYGLHPAAAAGAYSH-PAAAAAAAAAAALQY
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB9 PHHHHHHHVPHMSPNPGSTYMASCPVPAGPGG-VGAAGGGGGGDYGPDSSSSPVPSSPAM
:. .: ..: . :: :.: .: ... :.. :: . . . :
NP_036 PYA-----LPPVAP------VLPPAVPLLPSGELGRKAAAFGSQLGPGLQLQLNSLGAAA
310 320 330 340 350
330 340 350 360 370
pF1KB9 ASAIECHSPYTSPAAHWSSPGASPYLK-------QPPALTPSSNPAASAGLHSSMSSYSL
:.: . :. . : :.: : .. : : :. :. :: .. .. :
NP_036 AAAGTAGAAGTTASLIKSEPSARPSFSIENIIGGGPAAPGGSAVGAGVAGGTGGSGGGST
360 370 380 390 400 410
380 390 400 410 420 430
pF1KB9 EQSYLHQNAREDLSVGLPRYQHHSTPVCDRKDFVLNFNGISSFHPSASGSYYHHHHQSVC
::.:
NP_036 AQSFLRPPGTVQSAALMATHQPLSLSRTTATIAPILSVPLSGQFLQPAASAAAAAAAAAQ
420 430 440 450 460 470
>>NP_004464 (OMIM: 241850,602617,616534) forkhead box pr (373 aa)
initn: 579 init1: 473 opt: 567 Z-score: 343.3 bits: 72.4 E(85289): 2.2e-12
Smith-Waterman score: 570; 35.2% identity (61.0% similar) in 318 aa overlap (70-374:25-325)
40 50 60 70 80 90
pF1KB9 AAPETTSSSSSSSSASCASSSSSSNSASAPSAACKSAGGGGAGAGSGGAKKASSGLRRPE
.:: .. : ..: :.:: .. . :.:
NP_004 MTAESGPPPPQPEVLATVKEERGETAAGAGVPGEATGRGAGG-RRRKRPLQRG-
10 20 30 40 50
100 110 120 130 140 150
pF1KB9 KPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFI
::::::::::.::: .: .::::. ::.:. ::::.: . :.::.::::.::.::.
NP_004 KPPYSYIALIAMAIAHAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFL
60 70 80 90 100 110
160 170 180 190 200 210
pF1KB9 KLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMY-HRVVSGLGFGA
:.:. ::::::.::..:: .: ::: ::: :: . :.:. . : : : .... . .:
NP_004 KIPREAGRPGKGNYWALDPNAEDMFESGSFLRRRKRFKRSDLSTYPAYMHDAAAAAAAAA
120 130 140 150 160 170
220 230 240 250 260 270
pF1KB9 SLLPQGFDFQAPPSAPLGCHSQGGYGGLDMMPAGYDAGAGAPSHAHPHHHHHHHVPHMSP
. . : : ..: .. : :.. :: . :: : : .. : ::
NP_004 AAAAAAAIF--PGAVPA---ARPPY------PGAVYAGYAPPSLAAPPPVYY---PAASP
180 190 200 210
280 290 300 310 320 330
pF1KB9 NPGSTYMASCPVPAGPGGVGAAGGGGGGDYGPDSSSSPVPSS---PAMASAIECHSPYTS
.: .. : .: .: : .: ::. . :...:. .. :: .. . .: .
NP_004 GPCRVFGLVPERPLSPE-LGPAPSGPGGSCAFASAGAPATTTGYQPAGCTGARPANPSAY
220 230 240 250 260 270
340 350 360 370 380
pF1KB9 PAAHWSSPGASPYLKQPPALT-------PSSNPA--ASAGLHSSMSSYSLEQSYLHQNAR
::. . :: : .. :.: :: .:.:...... :
NP_004 AAAYAGPDGAYPQGAGSAIFAAAGRLAGPASPPAGGSSGGVETTVDFYGRTSPGQFGALG
280 290 300 310 320 330
390 400 410 420 430 440
pF1KB9 EDLSVGLPRYQHHSTPVCDRKDFVLNFNGISSFHPSASGSYYHHHHQSVCQDIKPCVM
NP_004 ACYNPGGQLGGASAGAYHARHAAAYPGGIDRFVSAM
340 350 360 370
>>NP_150285 (OMIM: 612788) forkhead box protein Q1 [Homo (403 aa)
initn: 497 init1: 379 opt: 556 Z-score: 336.6 bits: 71.3 E(85289): 5.2e-12
Smith-Waterman score: 565; 33.8% identity (56.5% similar) in 379 aa overlap (5-364:25-386)
10 20 30 40
pF1KB9 MTTEGGPPPAPLRRACSPVPGALQAALMSPPPAAAAAAAA
:. :.:: : . :. . : :...: .
NP_150 MKLEVFVPRAAHGDKQGSDLEGAGGSDAPSPLSAAGDDSLGSDGDCAANSPAAGGGARDT
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 APETTSSSSSSSSASCASSSSSSNSASAPSAACKSAGGGGAGAGSGGAKKASSGLRRPEK
. .:.... .: : .... .. : .: .:: :..::::: . ... ::: :
NP_150 QGDGEQSAGGGPGAEEAIPAAAAAAVVAEGAEAGAAGPGAGGAGSGEGARSKPYTRRP-K
70 80 90 100 110
110 120 130 140 150 160
pF1KB9 PPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIK
:::::::::.:::..: . ::::.:: ..:...::::::.: ::.::::::::::.::.:
NP_150 PPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVK
120 130 140 150 160 170
170 180 190 200 210
pF1KB9 LPKGLGRP-GKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYHRV-VSGLGFGA
. . .:: :: .:: ..: ::. : .: :::: :.. . ::. : . :.
NP_150 VLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRR----RKR------LSHRAPVPAPGLRP
180 190 200 210 220
220 230 240 250 260 270
pF1KB9 SLLPQGFDFQAPPSAPLGCHSQGGYGGLDMMPAGYDAGAGAPSHAHPH--HHHHHHVPHM
: :. ::: :: . : . . . :: . : : .. .
NP_150 EEAP-GLP-AAPPPAPAAPASPRMRSPARQEERASPAGKFSSSFAIDSILRKPFRSRRLR
230 240 250 260 270 280
280 290 300 310 320
pF1KB9 SPNPGSTYM---ASCP-VPAGPGGVGAA-----------GGGGGGDYGPDSSSSPVPSSP
. ::.: . : :: .:: :. . :: :.: . : . : :..:
NP_150 DTAPGTTLQWGAAPCPPLPAFPALLPAAPCRALLPLCAYGAGEPARLGAREAEVP-PTAP
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB9 AMASAIECHSPYTSPAAHWSSPGASPYLKQPPALTPSSNPAASAGLHSSMSSYSLEQSYL
. : : ..:: .:.:. : :.. :::
NP_150 PLLLA---PLPAAAPAKPLRGPAAGGAHLYCPLRLPAALQAASVRRPGPHLPYPVETLLA
350 360 370 380 390 400
390 400 410 420 430 440
pF1KB9 HQNAREDLSVGLPRYQHHSTPVCDRKDFVLNFNGISSFHPSASGSYYHHHHQSVCQDIKP
>>NP_075555 (OMIM: 110100,605597,608996) forkhead box pr (376 aa)
initn: 474 init1: 449 opt: 519 Z-score: 316.0 bits: 67.4 E(85289): 7.3e-11
Smith-Waterman score: 571; 34.3% identity (53.4% similar) in 399 aa overlap (30-389:6-376)
10 20 30 40 50 60
pF1KB9 MTTEGGPPPAPLRRACSPVPGALQAALMSPPPAAAAAAAAAPETTSSSSSSSSASCASSS
: : ::.: ::::
NP_075 MMASYPEPEDAAGALLAPET----------------
10 20
70 80 90 100 110 120
pF1KB9 SSSNSASAPSAACKSAGGGGAGAGSGGAKKASSGLRRPEKPPYSYIALIVMAIQSSPSKR
. ... : . : : ::.:.:. . .: . . .::::::.:::.:::. : ::
NP_075 --GRTVKEPEGPPPSPGKGGGGGGGTAPEKPDPA----QKPPYSYVALIAMAIRESAEKR
30 40 50 60 70
130 140 150 160 170 180
pF1KB9 LTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPAS
:::: :::.. :.:::.. .::.::.::::::::::::.:. : ::.:::.:::
NP_075 LTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGGERKGNYWTLDPAC
80 90 100 110 120 130
190 200 210 220 230
pF1KB9 EFMFEEGSFRRR---PRGFRRKCQALKP---MYHRVVSGLGFG-ASLLPQGFDFQAPP--
: :::.:..::: : :: ..: .. .. : : :. .:. . :::
NP_075 EDMFEKGNYRRRRRMKRPFRPPPAHFQPGKGLFGAGGAAGGCGVAGAGADGYGYLAPPKY
140 150 160 170 180 190
240 250 260 270 280
pF1KB9 --------SAPLGCH-SQGGYGGLDMMPAGYDAGAGAPSHAHPHHHHHHHVPHMSPNPGS
: :: : :.. .: :. :.:.: . : : : . .:..
NP_075 LQSGFLNNSWPLPQPPSPMPYASCQMAAAAA-AAAAAAAAAGPGSPGAAAVVKGLAGPAA
200 210 220 230 240 250
290 300 310 320 330
pF1KB9 TY-----MASCPVPAGPGGVGAAGGGGGGDYGPDSSSSPVPSSPAMASAIECHSPYTSPA
.: . : .: :: :.. .: :: .: : : : .: .:
NP_075 SYGPYTRVQSMALP--PGVVNSYNGLGGPPAAPPPPPHPHPH-PHAHHLHAAAAPPPAPP
260 270 280 290 300 310
340 350 360 370 380
pF1KB9 AHWSS---PG----ASPYLKQPPALTPSSNPAAS---------AGLHSSMSSYSLEQSYL
: .. :: ::: ::: .:.: :. . : .: :. ... . . :
NP_075 HHGAAAPPPGQLSPASPATAAPPAPAPTSAPGLQFACARQPELAMMHCSYWDHDSKTGAL
320 330 340 350 360 370
390 400 410 420 430 440
pF1KB9 HQNAREDLSVGLPRYQHHSTPVCDRKDFVLNFNGISSFHPSASGSYYHHHHQSVCQDIKP
: .: ::
NP_075 H--SRLDL
>>NP_001444 (OMIM: 601090,601631,602482) forkhead box pr (553 aa)
initn: 621 init1: 481 opt: 521 Z-score: 314.9 bits: 67.7 E(85289): 8.5e-11
Smith-Waterman score: 557; 37.4% identity (56.5% similar) in 329 aa overlap (67-393:48-332)
40 50 60 70 80 90
pF1KB9 AAAAAPETTSSSSSSSSASCASSSSSSNSASAPSAACKSAGGGGAGAGSGGAKKASSGLR
: :. : . :: . . : . . .
NP_001 YLGGEQSYYRAAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGGMARAYGPYTPQPQPKDMV
20 30 40 50 60 70
100 110 120 130 140 150
pF1KB9 RPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNE
::::::::::.::::..:.:..::. ::::.. ::::.: :::.::.::::::::
NP_001 ---KPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNKQGWQNSIRHNLSLNE
80 90 100 110 120 130
160 170 180 190 200 210
pF1KB9 CFIKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYHRVVSGLGF
::.:.:. .:::: :::.:: : :::.::: :: : :..: .:.: .. :
NP_001 CFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKK-DAVKDKEEKDRLHLKE
140 150 160 170 180 190
220 230 240 250 260 270
pF1KB9 GASLLPQGFDFQAPPSAPLGCHSQGGYGGLDMMPAGYDAGAGAPSHAHPHHHHHHHVPHM
: : . :: :: : :..: .: .: : .
NP_001 PP---PPG---RQPPPAP---------------PEQADGNAPGP---QP--------PPV
200 210 220
280 290 300 310 320 330
pF1KB9 SPNPGSTYMASCPVPAGPGGVGAAGGGGGGDYGPDSSSSPVPSSPAMASAIECHSPYTSP
. .: ..:: : : . .:: :.:.. : . :: :: ...:. : . :
NP_001 RIQDIKTENGTCPSPPQPLSPAAALGSGSAAAVP-KIESPDSSSSSLSSG--SSPPGSLP
230 240 250 260 270
340 350 360 370 380 390
pF1KB9 AAH-WSSPGASPYLKQPPALTPSSNPAA-SAGLHSSMSSYSLEQSYLHQNAREDLSVGLP
.:. : ::. . :: .::. : : :. . ::. : :.: .:: ::
NP_001 SARPLSLDGAD---SAPPPPAPSAPPPHHSQGFSVDNIMTSLRGS--PQSAAAELSSGLL
280 290 300 310 320 330
400 410 420 430 440
pF1KB9 RYQHHSTPVCDRKDFVLNFNGISSFHPSASGSYYHHHHQSVCQDIKPCVM
NP_001 ASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQTSSAGSSGGGGGGAGAAGGAGGAGTY
340 350 360 370 380 390
>>NP_004109 (OMIM: 602939) forkhead box protein S1 [Homo (330 aa)
initn: 488 init1: 463 opt: 507 Z-score: 309.9 bits: 66.1 E(85289): 1.6e-10
Smith-Waterman score: 507; 37.8% identity (59.1% similar) in 286 aa overlap (98-366:16-283)
70 80 90 100 110 120
pF1KB9 APSAACKSAGGGGAGAGSGGAKKASSGLRRPEKPPYSYIALIVMAIQSSPSKRLTLSEIY
: ::::::::::.:::::::..: ::: ::
NP_004 MQQQPLPGPGAPTTEPTKPPYSYIALIAMAIQSSPGQRATLSGIY
10 20 30 40
130 140 150 160 170 180
pF1KB9 QFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEEG
.....:: :.: ::.::.::::::::::.:.:. .:::: :::.:: . :::.:
NP_004 RYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTLDPDCHDMFEHG
50 60 70 80 90 100
190 200 210 220 230 240
pF1KB9 SFRRRPRGFRRKCQALK---PMYHRV----VSGLGFGASLLPQGFDFQAPPSAPLGCHSQ
:: :: : : :. : : : ... :. : . . :: : .
NP_004 SFLRRRRRFTRQTGAEGTRGPAKARRGPLRATSQDPGVPNATTGRQCSFPPELP---DPK
110 120 130 140 150 160
250 260 270 280 290
pF1KB9 G-GYGGL-DMMPAGYDAGAGAPSHAHPHHHHHHHVPHMSPNPGSTYMASCP----VPAGP
: ..::: :::.. : . ..:. : : :. :: .:: : ..
NP_004 GLSFGGLVGAMPASM---CPATTDGRPR-------PPMEPKEISTPKPACPGELPVATSS
170 180 190 200 210
300 310 320 330 340 350
pF1KB9 GGVGAAGGGGGGDYGPDSSSSPVPS-SP--AMASAIECHSPYTSPAAHWSSPGASPYLKQ
.. : : .: . . . ...:.: :: ...:. .:. : .. ::.: :..
NP_004 SSCPAFGFPAGFSEAESFNKAPTPVLSPESGIGSSYQCRLQ----ALNFCM-GADPGLEH
220 230 240 250 260
360 370 380 390 400 410
pF1KB9 PPA-LTPSSNPAASAGLHSSMSSYSLEQSYLHQNAREDLSVGLPRYQHHSTPVCDRKDFV
: .:: : . :
NP_004 LLASAAPSPAPPTPPGSLRAPLPLPTDHKEPWVAGGFPVQGGSGYPLGLTPCLYRTPGMF
270 280 290 300 310 320
444 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 01:09:42 2016 done: Sat Nov 5 01:09:43 2016
Total Scan time: 9.600 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]