Result of FASTA (ccds) for
pFN21AE0502
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0502, 211 aa
1>>>pF1KE0502 211 - 211 aa - 211 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2150+/-0.000662; mu= 13.5673+/- 0.040
mean_var=57.3171+/-11.571, 0's: 0 Z-trim(109.1): 17 B-trim: 0 in 0/51
Lambda= 0.169407
statistics sampled from 10663 (10680) to 10663 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.328), width: 16
Scan time: 1.900
The best scores are: opt bits E(32554)
CCDS13830.1 CRYBB3 gene_id:1417|Hs108|chr22 ( 211) 1479 369.2 1e-102
CCDS13840.1 CRYBB1 gene_id:1414|Hs108|chr22 ( 252) 855 216.7 9.8e-57
CCDS13831.1 CRYBB2 gene_id:1415|Hs108|chr22 ( 205) 840 213.0 1e-55
CCDS11249.1 CRYBA1 gene_id:1411|Hs108|chr17 ( 215) 580 149.5 1.5e-36
CCDS13841.1 CRYBA4 gene_id:1413|Hs108|chr22 ( 196) 508 131.9 2.7e-31
CCDS2429.1 CRYBA2 gene_id:1412|Hs108|chr2 ( 197) 494 128.5 2.9e-30
CCDS3275.1 CRYGS gene_id:1427|Hs108|chr3 ( 178) 416 109.4 1.4e-24
CCDS2379.1 CRYGC gene_id:1420|Hs108|chr2 ( 174) 400 105.5 2.1e-23
CCDS2380.1 CRYGB gene_id:1419|Hs108|chr2 ( 175) 386 102.1 2.3e-22
CCDS33367.1 CRYGA gene_id:1418|Hs108|chr2 ( 174) 382 101.1 4.5e-22
CCDS2378.1 CRYGD gene_id:1421|Hs108|chr2 ( 174) 361 95.9 1.6e-20
CCDS5926.1 CRYGN gene_id:155051|Hs108|chr7 ( 182) 305 82.3 2.2e-16
CCDS78289.1 CRYGN gene_id:155051|Hs108|chr7 ( 125) 251 69.0 1.5e-12
>>CCDS13830.1 CRYBB3 gene_id:1417|Hs108|chr22 (211 aa)
initn: 1479 init1: 1479 opt: 1479 Z-score: 1957.5 bits: 369.2 E(32554): 1e-102
Smith-Waterman score: 1479; 99.5% identity (99.5% similar) in 211 aa overlap (1-211:1-211)
10 20 30 40 50 60
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPDHKLHLFE
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
CCDS13 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
130 140 150 160 170 180
190 200 210
pF1KE0 WNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
:::::::::::::::::::::::::::::::
CCDS13 WNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
190 200 210
>>CCDS13840.1 CRYBB1 gene_id:1414|Hs108|chr22 (252 aa)
initn: 855 init1: 855 opt: 855 Z-score: 1132.0 bits: 216.7 E(32554): 9.8e-57
Smith-Waterman score: 855; 56.9% identity (85.6% similar) in 188 aa overlap (22-209:57-244)
10 20 30 40 50
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDS
:.:.....:::::::.: :.:.:: .:.:
CCDS13 PPAGTSPSPGTTLAPTTVPITSAKAAELPPGNYRLVVFELENFQGRRAEFSGECSNLADR
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE0 LLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDS
...: :: : .:::.:::. ::::.:.::::.::::..::.: :: :.:.::...:.
CCDS13 GFDRVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTWSSSYRSDRLMSFRPIKMDA
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE0 PDHKLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQY
.::. :::. :.: .:: ::.::::..::.:::.::.. .::::::..::::: ::
CCDS13 QEHKISLFEGANFKGNTIEIQGDDAPSLWVYGFSDRVGSVKVSSGTWVGYQYPGYRGYQY
150 160 170 180 190 200
180 190 200 210
pF1KE0 VFERGEYRHWNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
..: :..:::::: : :::.::.::.::..:: .: ::
CCDS13 LLEPGDFRHWNEWGAFQPQMQSLRRLRDKQWHLEGSFPVLATEPPK
210 220 230 240 250
>>CCDS13831.1 CRYBB2 gene_id:1415|Hs108|chr22 (205 aa)
initn: 937 init1: 807 opt: 840 Z-score: 1113.6 bits: 213.0 E(32554): 1e-55
Smith-Waterman score: 840; 53.8% identity (83.0% similar) in 212 aa overlap (1-211:1-205)
10 20 30 40 50 60
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
:: .: :. ::: .. . :.:..: :::::. ::.. ::.: .. .::.::.
CCDS13 MASDH----QTQAGKPQSL---NPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVL
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPDHKLHLFE
:..:::...:. .:::::.:::.:::::.:..:: .::: ::::...:: .::. :.:
CCDS13 VQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
:: :.:.::::.::::::. :::.:..:.:::. .::::::..::::: ::..:.:.:.
CCDS13 NPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKD
120 130 140 150 160 170
190 200 210
pF1KE0 WNEWDASQPQLQSVRRIRDQKWHKRGRF-PSS
... : .::.::::::::..::.:: : ::.
CCDS13 SSDFGAPHPQVQSVRRIRDMQWHQRGAFHPSN
180 190 200
>>CCDS11249.1 CRYBA1 gene_id:1411|Hs108|chr17 (215 aa)
initn: 572 init1: 307 opt: 580 Z-score: 769.9 bits: 149.5 E(32554): 1.5e-36
Smith-Waterman score: 598; 43.5% identity (74.0% similar) in 200 aa overlap (9-198:17-214)
10 20 30 40 50
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSL
..: .. . :.:: .:. .:. ::::::: :... ::....
CCDS11 METQAEQQELETLPTTKMAQTNPTPGSLG-PWKITIYDQENFQGKRMEFTSSCPNVSERS
10 20 30 40 50
60 70 80 90 100
pF1KE0 LEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWDAWS--NSRDSDSLLSLRPL-NI
...: :..:::: :...: .: :.::.::.:.:::::::: :. . :.:.::. .
CCDS11 FDNVRSLKVESGAWIGYEHTSFCGQQFILERGEYPRWDAWSGSNAYHIERLMSFRPICSA
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE0 DSPDHKLHLFENPAFSGRKMEIVDDDVPSLWAHG-FQDRVASVRAINGTWVGYEFPGYRG
. . :. .::. : ::. :: .:: ::: : : :...:.:.. .:.:: :..:::::
CCDS11 NHKESKMTIFEKENFIGRQWEI-SDDYPSLQAMGWFNNEVGSMKIQSGAWVCYQYPGYRG
120 130 140 150 160 170
170 180 190 200 210
pF1KE0 RQYVFE----RGEYRHWNEWD--ASQPQLQSVRRIRDQKWHKRGRFPSS
::..: :.:.:: :: :. :.::.:::.
CCDS11 YQYILECDHHGGDYKHWREWGSHAQTSQIQSIRRIQQ
180 190 200 210
>>CCDS13841.1 CRYBA4 gene_id:1413|Hs108|chr22 (196 aa)
initn: 447 init1: 250 opt: 508 Z-score: 675.4 bits: 131.9 E(32554): 2.7e-31
Smith-Waterman score: 526; 42.2% identity (72.2% similar) in 187 aa overlap (22-198:10-195)
10 20 30 40 50 60
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
: .:..... ..:::.: :..:::::. . .: : :..
CCDS13 MTLQCTKSAGPWKMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLK
10 20 30 40
70 80 90 100 110
pF1KE0 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAW--SNSRDSDSLLSLRPLN-IDSPDHKLH
: :: :..:: .:.:.:..::.:.:: :::: ... .. : :.:: . : .:
CCDS13 VLSGAWVGFEHAGFQGQQYILERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLT
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE0 LFENPAFSGRKMEIVDDDVPSLWAHGFQ-DRVASVRAINGTWVGYEFPGYRGRQYVFE--
.::. : :.: :. .:: ::: : :.. ..:.: .. .:.:: .:::::: :::.:
CCDS13 IFEQENFLGKKGEL-SDDYPSLQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECD
110 120 130 140 150 160
180 190 200 210
pF1KE0 --RGEYRHWNEWDASQP--QLQSVRRIRDQKWHKRGRFPSS
:.:.:. :: . : :.::.:::.
CCDS13 HHSGDYKHFREWGSHAPTFQVQSIRRIQQ
170 180 190
>>CCDS2429.1 CRYBA2 gene_id:1412|Hs108|chr2 (197 aa)
initn: 469 init1: 211 opt: 494 Z-score: 656.9 bits: 128.5 E(32554): 2.9e-30
Smith-Waterman score: 521; 45.6% identity (75.8% similar) in 182 aa overlap (28-198:16-196)
10 20 30 40 50
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTD-SLLEKVGSI
:.. :.:::.::.: ..: .. . . : .: :.
CCDS24 MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSV
10 20 30 40
60 70 80 90 100 110
pF1KE0 QVESGPWLAFESRAFRGEQFVLEKGDYPRWDAWS--NSRDSDSLLSLRP-LNIDSPDHKL
.::.: :.::: :.:.::.:::::::::.::: .:..:..:::.:: : . : ..
CCDS24 KVENGVWVAFEYPDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRV
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE0 HLFENPAFSGRKMEIVDDDVPSLWAHGFQDR-VASVRAINGTWVGYEFPGYRGRQYVFER
:::. :.: :...::: ::: . :. .. :.:... .:.::.:..::::: :::.::
CCDS24 TLFEGDNFQGCKFDLVDD-YPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLER
110 120 130 140 150 160
180 190 200 210
pF1KE0 ----GEYRHWNEW--DASQPQLQSVRRIRDQKWHKRGRFPSS
::. ..: .: ::::.::..
CCDS24 DRHSGEFCTYGELGTQAHTGQLQSIRRVQH
170 180 190
>>CCDS3275.1 CRYGS gene_id:1427|Hs108|chr3 (178 aa)
initn: 354 init1: 203 opt: 416 Z-score: 554.6 bits: 109.4 E(32554): 1.4e-24
Smith-Waterman score: 416; 35.6% identity (70.7% similar) in 174 aa overlap (25-197:7-176)
10 20 30 40 50 60
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
:. .:: .::::.: . . .: .. . : . .::.
CCDS32 MSKTGTKITFYEDKNFQGRRYDCDCDCADF-HTYLSRCNSIK
10 20 30 40
70 80 90 100 110
pF1KE0 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSP-DHKLHLF
::.: : ..: : : ...: .:.::... : . .: : : : ... : ..:...:
CCDS32 VEGGTWAVYERPNFAGYMYILPQGEYPEYQRWMGL--NDRLSSCRAVHLPSGGQYKIQIF
50 60 70 80 90
120 130 140 150 160 170
pF1KE0 ENPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYR
:. :::. .: . .: ::. . . .. : ....:.:. ::.:.::::::.... :::
CCDS32 EKGDFSGQMYE-TTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYR
100 110 120 130 140 150
180 190 200 210
pF1KE0 HWNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
. .: :..: .:: :::
CCDS32 KPIDWGAASPAVQSFRRIVE
160 170
>>CCDS2379.1 CRYGC gene_id:1420|Hs108|chr2 (174 aa)
initn: 347 init1: 168 opt: 400 Z-score: 533.6 bits: 105.5 E(32554): 2.1e-23
Smith-Waterman score: 400; 34.9% identity (68.0% similar) in 175 aa overlap (25-199:3-172)
10 20 30 40 50 60
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
:. .:: . :::. : ...::.: . . . .::.
CCDS23 MGKITFYEDRAFQGRSYETTTDCPNL-QPYFSRCNSIR
10 20 30
70 80 90 100 110 120
pF1KE0 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPDHKLHLFE
:::: :. .: ..:.:..:..:.:: .. : . :: : : ... :.:.:.:
CCDS23 VESGCWMLYERPNYQGQQYLLRRGEYPDYQQWMGLSDSIRSCCLIPQTVS---HRLRLYE
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE0 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
.: ::. ..: ::. . ... :.....: :: ::.:.::::::... :::.
CCDS23 REDHKGLMMEL-SEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRR
100 110 120 130 140 150
190 200 210
pF1KE0 WNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
..: : . . :.::. :
CCDS23 CQDWGAMDAKAGSLRRVVDLY
160 170
>>CCDS2380.1 CRYGB gene_id:1419|Hs108|chr2 (175 aa)
initn: 360 init1: 185 opt: 386 Z-score: 515.0 bits: 102.1 E(32554): 2.3e-22
Smith-Waterman score: 386; 32.6% identity (67.4% similar) in 175 aa overlap (25-199:3-173)
10 20 30 40 50 60
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
:. .:: . :::. : ...::.: . . . .::.
CCDS23 MGKITFYEDRAFQGRSYECTTDCPNL-QPYFSRCNSIR
10 20 30
70 80 90 100 110 120
pF1KE0 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPDHKLHLFE
:::: :. .: ..:.:. :..:.:: .. : . :: : : . : .......
CCDS23 VESGCWMIYERPNYQGHQYFLRRGEYPDYQQWMGLSDSIRSCCLIPPH--SGAYRMKIYD
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE0 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
. :. :..:: . :. . .. :. ...:.:. ::.:.::::::... ::::.
CCDS23 RDELRGQMSELTDDCI-SVQDRFHLTEIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRR
100 110 120 130 140 150
190 200 210
pF1KE0 WNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
. .: : . .. :.::. :
CCDS23 FLDWGAPNAKVGSLRRVMDLY
160 170
>>CCDS33367.1 CRYGA gene_id:1418|Hs108|chr2 (174 aa)
initn: 380 init1: 177 opt: 382 Z-score: 509.8 bits: 101.1 E(32554): 4.5e-22
Smith-Waterman score: 382; 36.0% identity (68.0% similar) in 178 aa overlap (25-199:3-172)
10 20 30 40 50
pF1KE0 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRC-ELSAECPSLTDSLLEKVGSI
:. .:: ..::: :: . ..::.: . . .::
CCDS33 MGKITFYEDRDFQG-RCYNCISDCPNLR-VYFSRCNSI
10 20 30
60 70 80 90 100 110
pF1KE0 QVESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPDHKLHLF
.:.:: :. .: ..:.:. :..: :: .. : . :::. : : . : .:::.:.
CCDS33 RVDSGCWMLYERPNYQGHQYFLRRGKYPDYQHWMGL--SDSVQSCRIIPHTS-SHKLRLY
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE0 ENPAFSGRKMEIVDDD--VPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGE
: . : :..:: :: :. .. :.....: :: ::.:.::::::... :.
CCDS33 ERDDYRGLMSELTDDCACVPELFR---LPEIYSLHVLEGCWVLYEMPNYRGRQYLLRPGD
100 110 120 130 140 150
180 190 200 210
pF1KE0 YRHWNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
::....: ... .. :.::. :
CCDS33 YRRYHDWGGADAKVGSLRRVTDLY
160 170
211 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 03:55:33 2016 done: Thu Nov 3 03:55:33 2016
Total Scan time: 1.900 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]