Result of FASTA (omim) for
pFN21AE0501
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0501, 205 aa
1>>>pF1KE0501 205 - 205 aa - 205 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2690+/-0.000316; mu= 13.4563+/- 0.020
mean_var=63.0983+/-12.606, 0's: 0 Z-trim(115.8): 32 B-trim: 0 in 0/57
Lambda= 0.161460
statistics sampled from 26486 (26518) to 26486 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.311), width: 16
Scan time: 6.020
The best scores are: opt bits E(85289)
XP_011528202 (OMIM: 123620,601547) PREDICTED: beta ( 205) 1442 344.1 9.3e-95
XP_006724204 (OMIM: 123620,601547) PREDICTED: beta ( 205) 1442 344.1 9.3e-95
NP_000487 (OMIM: 123620,601547) beta-crystallin B2 ( 205) 1442 344.1 9.3e-95
NP_004067 (OMIM: 123630,609741) beta-crystallin B3 ( 211) 838 203.4 2.1e-52
XP_011528204 (OMIM: 123630,609741) PREDICTED: beta ( 267) 838 203.5 2.6e-52
NP_001878 (OMIM: 600929,611544) beta-crystallin B1 ( 252) 805 195.8 5.1e-50
XP_011528201 (OMIM: 600929,611544) PREDICTED: beta ( 252) 805 195.8 5.1e-50
NP_005199 (OMIM: 123610,600881) beta-crystallin A3 ( 215) 579 143.1 3.2e-34
XP_016879687 (OMIM: 123610,600881) PREDICTED: beta ( 316) 579 143.2 4.4e-34
NP_001877 (OMIM: 123631,610425) beta-crystallin A4 ( 196) 512 127.5 1.5e-29
XP_006724203 (OMIM: 123631,610425) PREDICTED: beta ( 201) 512 127.5 1.5e-29
XP_016884087 (OMIM: 123631,610425) PREDICTED: beta ( 207) 512 127.5 1.5e-29
NP_476435 (OMIM: 115900,600836) beta-crystallin A2 ( 197) 478 119.5 3.6e-27
NP_476434 (OMIM: 115900,600836) beta-crystallin A2 ( 197) 478 119.5 3.6e-27
NP_060011 (OMIM: 116100,123730) beta-crystallin S ( 178) 406 102.8 3.6e-22
NP_005201 (OMIM: 123670,615188) gamma-crystallin B ( 175) 398 100.9 1.3e-21
XP_011514138 (OMIM: 609603) PREDICTED: gamma-cryst ( 295) 399 101.2 1.7e-21
XP_016858891 (OMIM: 123670,615188) PREDICTED: gamm ( 177) 396 100.4 1.8e-21
XP_005250009 (OMIM: 609603) PREDICTED: gamma-cryst ( 182) 395 100.2 2.2e-21
NP_066269 (OMIM: 123680,604307) gamma-crystallin C ( 174) 388 98.6 6.5e-21
XP_011508964 (OMIM: 123680,604307) PREDICTED: gamm ( 174) 388 98.6 6.5e-21
NP_055432 (OMIM: 123660) gamma-crystallin A [Homo ( 174) 380 96.7 2.4e-20
XP_016884088 (OMIM: 123630,609741) PREDICTED: beta ( 169) 364 93.0 3.1e-19
NP_008822 (OMIM: 115700,123690) gamma-crystallin D ( 174) 348 89.2 4.2e-18
XP_011514139 (OMIM: 609603) PREDICTED: gamma-cryst ( 260) 335 86.3 4.8e-17
XP_016865822 (OMIM: 601797) PREDICTED: absent in m (1544) 321 83.4 2.1e-15
NP_001615 (OMIM: 601797) absent in melanoma 1 prot (1723) 321 83.4 2.3e-15
XP_005266896 (OMIM: 601797) PREDICTED: absent in m (2131) 321 83.5 2.7e-15
NP_001295221 (OMIM: 609603) gamma-crystallin N iso ( 125) 228 61.2 8.2e-10
XP_016867262 (OMIM: 609603) PREDICTED: gamma-cryst ( 125) 228 61.2 8.2e-10
NP_653328 (OMIM: 609603) gamma-crystallin N isofor ( 182) 228 61.3 1.1e-09
>>XP_011528202 (OMIM: 123620,601547) PREDICTED: beta-cry (205 aa)
initn: 1442 init1: 1442 opt: 1442 Z-score: 1822.2 bits: 344.1 E(85289): 9.3e-95
Smith-Waterman score: 1442; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205)
10 20 30 40 50 60
pF1KE0 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 KMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAP
130 140 150 160 170 180
190 200
pF1KE0 HPQVQSVRRIRDMQWHQRGAFHPSN
:::::::::::::::::::::::::
XP_011 HPQVQSVRRIRDMQWHQRGAFHPSN
190 200
>>XP_006724204 (OMIM: 123620,601547) PREDICTED: beta-cry (205 aa)
initn: 1442 init1: 1442 opt: 1442 Z-score: 1822.2 bits: 344.1 E(85289): 9.3e-95
Smith-Waterman score: 1442; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205)
10 20 30 40 50 60
pF1KE0 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 KMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAP
130 140 150 160 170 180
190 200
pF1KE0 HPQVQSVRRIRDMQWHQRGAFHPSN
:::::::::::::::::::::::::
XP_006 HPQVQSVRRIRDMQWHQRGAFHPSN
190 200
>>NP_000487 (OMIM: 123620,601547) beta-crystallin B2 [Ho (205 aa)
initn: 1442 init1: 1442 opt: 1442 Z-score: 1822.2 bits: 344.1 E(85289): 9.3e-95
Smith-Waterman score: 1442; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205)
10 20 30 40 50 60
pF1KE0 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 KMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAP
130 140 150 160 170 180
190 200
pF1KE0 HPQVQSVRRIRDMQWHQRGAFHPSN
:::::::::::::::::::::::::
NP_000 HPQVQSVRRIRDMQWHQRGAFHPSN
190 200
>>NP_004067 (OMIM: 123630,609741) beta-crystallin B3 [Ho (211 aa)
initn: 965 init1: 805 opt: 838 Z-score: 1061.6 bits: 203.4 E(85289): 2.1e-52
Smith-Waterman score: 838; 53.8% identity (83.0% similar) in 212 aa overlap (1-205:1-211)
10 20 30 40 50
pF1KE0 MASDH----QTQAGKPQSL---NPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVL
:: .: :. ::: .. . :.:..: :::::. ::.. ::.: .. .::.::.
NP_004 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 VQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYE
:..:::...:. .:::::.:::.:::::.:..:: .::: ::::...:: .::. :.:
NP_004 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 NPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKD
:: :.:.::::.::::::. :::.:..:.:::. .::::::..::::: ::..:.:.:.
NP_004 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
130 140 150 160 170 180
180 190 200
pF1KE0 SSDFGAPHPQVQSVRRIRDMQWHQRGAFHPSN
... : .::.::::::::..::.:: : ::.
NP_004 WNEWDASQPQLQSVRRIRDQKWHKRGRF-PSS
190 200 210
>>XP_011528204 (OMIM: 123630,609741) PREDICTED: beta-cry (267 aa)
initn: 965 init1: 805 opt: 838 Z-score: 1060.1 bits: 203.5 E(85289): 2.6e-52
Smith-Waterman score: 838; 53.8% identity (83.0% similar) in 212 aa overlap (1-205:57-267)
10 20
pF1KE0 MASDH----QTQAGKPQSL---NPKIIIFE
:: .: :. ::: .. . :.:..:
XP_011 PLAKTGESADGRGSSVLPEATATARGVPGEMAEQHGAPEQAAAGKSHGDLGGSYKVILYE
30 40 50 60 70 80
30 40 50 60 70 80
pF1KE0 QENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWD
:::::. ::.. ::.: .. .::.::. :..:::...:. .:::::.:::.:::::
XP_011 LENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWD
90 100 110 120 130 140
90 100 110 120 130 140
pF1KE0 SWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIIDDDVPSFHAHGYQEKVSS
.:..:: .::: ::::...:: .::. :.::: :.:.::::.::::::. :::.:..:.:
XP_011 AWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVAS
150 160 170 180 190 200
150 160 170 180 190 200
pF1KE0 VRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQSVRRIRDMQWHQRGAFHP
::. .::::::..::::: ::..:.:.:. ... : .::.::::::::..::.:: : :
XP_011 VRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRIRDQKWHKRGRF-P
210 220 230 240 250 260
pF1KE0 SN
:.
XP_011 SS
>>NP_001878 (OMIM: 600929,611544) beta-crystallin B1 [Ho (252 aa)
initn: 934 init1: 788 opt: 805 Z-score: 1018.9 bits: 195.8 E(85289): 5.1e-50
Smith-Waterman score: 805; 55.9% identity (84.9% similar) in 186 aa overlap (16-201:58-243)
10 20 30 40
pF1KE0 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETG
: ....:: :::::. :..: : :: . :
NP_001 PAGTSPSPGTTLAPTTVPITSAKAAELPPGNYRLVVFELENFQGRRAEFSGECSNLADRG
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE0 VEKAGSVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQ
... :..:.:::::..::.: .::.:..::::::::..:.:: :.: : :.::::.:.:
NP_001 FDRVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTWSSSYRSDRLMSFRPIKMDAQ
90 100 110 120 130 140
110 120 130 140 150 160
pF1KE0 EHKIILYENPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYL
:::: :.:. :: :. .:: ::.::. ..:....:.::.:.:::::::::::::: :::
NP_001 EHKISLFEGANFKGNTIEIQGDDAPSLWVYGFSDRVGSVKVSSGTWVGYQYPGYRGYQYL
150 160 170 180 190 200
170 180 190 200
pF1KE0 LEKGDYKDSSDFGAPHPQVQSVRRIRDMQWHQRGAFHPSN
:: ::.. ...:: .::.::.::.:: ::: .:.:
NP_001 LEPGDFRHWNEWGAFQPQMQSLRRLRDKQWHLEGSFPVLATEPPK
210 220 230 240 250
>>XP_011528201 (OMIM: 600929,611544) PREDICTED: beta-cry (252 aa)
initn: 934 init1: 788 opt: 805 Z-score: 1018.9 bits: 195.8 E(85289): 5.1e-50
Smith-Waterman score: 805; 55.9% identity (84.9% similar) in 186 aa overlap (16-201:58-243)
10 20 30 40
pF1KE0 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETG
: ....:: :::::. :..: : :: . :
XP_011 PAGTSPSPGTTLAPTTVPITSAKAAELPPGNYRLVVFELENFQGRRAEFSGECSNLADRG
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE0 VEKAGSVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQ
... :..:.:::::..::.: .::.:..::::::::..:.:: :.: : :.::::.:.:
XP_011 FDRVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTWSSSYRSDRLMSFRPIKMDAQ
90 100 110 120 130 140
110 120 130 140 150 160
pF1KE0 EHKIILYENPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYL
:::: :.:. :: :. .:: ::.::. ..:....:.::.:.:::::::::::::: :::
XP_011 EHKISLFEGANFKGNTIEIQGDDAPSLWVYGFSDRVGSVKVSSGTWVGYQYPGYRGYQYL
150 160 170 180 190 200
170 180 190 200
pF1KE0 LEKGDYKDSSDFGAPHPQVQSVRRIRDMQWHQRGAFHPSN
:: ::.. ...:: .::.::.::.:: ::: .:.:
XP_011 LEPGDFRHWNEWGAFQPQMQSLRRLRDKQWHLEGSFPVLATEPPK
210 220 230 240 250
>>NP_005199 (OMIM: 123610,600881) beta-crystallin A3 [Ho (215 aa)
initn: 511 init1: 282 opt: 579 Z-score: 735.4 bits: 143.1 E(85289): 3.2e-34
Smith-Waterman score: 585; 46.1% identity (76.4% similar) in 191 aa overlap (12-191:25-214)
10 20 30 40
pF1KE0 MASDHQTQAGKPQSLNP-KIIIFEQENFQGHSHELNGPCPNLKETGV
: ::.: :: :..::::::. :... :::..: .
NP_005 METQAEQQELETLPTTKMAQTNPTPGSLGPWKITIYDQENFQGKRMEFTSSCPNVSERSF
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 EKAGSVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSR--RTDSLSSLRPI-KVD
... :. :..: :.:::... :.::..:.:::::::.:..: . . : :.::: ...
NP_005 DNVRSLKVESGAWIGYEHTSFCGQQFILERGEYPRWDAWSGSNAYHIERLMSFRPICSAN
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 SQEHKIILYENPNFTGKKMEIIDDDVPSFHAHG-YQEKVSSVRVQSGTWVGYQYPGYRGL
.: :. ..:. :: :.. :: .:: ::..: : ....:.:...:::.:: ::::::::
NP_005 HKESKMTIFEKENFIGRQWEI-SDDYPSLQAMGWFNNEVGSMKIQSGAWVCYQYPGYRGY
130 140 150 160 170
170 180 190 200
pF1KE0 QYLLE----KGDYKDSSDFG--APHPQVQSVRRIRDMQWHQRGAFHPSN
::.:: :::: ..: : :.::.:::.
NP_005 QYILECDHHGGDYKHWREWGSHAQTSQIQSIRRIQQ
180 190 200 210
>>XP_016879687 (OMIM: 123610,600881) PREDICTED: beta-cry (316 aa)
initn: 495 init1: 282 opt: 579 Z-score: 732.9 bits: 143.2 E(85289): 4.4e-34
Smith-Waterman score: 585; 46.1% identity (76.4% similar) in 191 aa overlap (12-191:126-315)
10 20 30 40
pF1KE0 MASDHQTQAGKPQSLNP-KIIIFEQENFQGHSHELNGPCPN
: ::.: :: :..::::::. :... :::
XP_016 PPPPKRPHHSCVLCLPETLPTTKMAQTNPTPGSLGPWKITIYDQENFQGKRMEFTSSCPN
100 110 120 130 140 150
50 60 70 80 90
pF1KE0 LKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSR--RTDSLSSLR
..: . ... :. :..: :.:::... :.::..:.:::::::.:..: . . : :.:
XP_016 VSERSFDNVRSLKVESGAWIGYEHTSFCGQQFILERGEYPRWDAWSGSNAYHIERLMSFR
160 170 180 190 200 210
100 110 120 130 140 150
pF1KE0 PI-KVDSQEHKIILYENPNFTGKKMEIIDDDVPSFHAHG-YQEKVSSVRVQSGTWVGYQY
:: ... .: :. ..:. :: :.. :: .:: ::..: : ....:.:...:::.:: :::
XP_016 PICSANHKESKMTIFEKENFIGRQWEI-SDDYPSLQAMGWFNNEVGSMKIQSGAWVCYQY
220 230 240 250 260 270
160 170 180 190 200
pF1KE0 PGYRGLQYLLE----KGDYKDSSDFG--APHPQVQSVRRIRDMQWHQRGAFHPSN
::::: ::.:: :::: ..: : :.::.:::.
XP_016 PGYRGYQYILECDHHGGDYKHWREWGSHAQTSQIQSIRRIQQ
280 290 300 310
>>NP_001877 (OMIM: 123631,610425) beta-crystallin A4 [Ho (196 aa)
initn: 477 init1: 237 opt: 512 Z-score: 651.7 bits: 127.5 E(85289): 1.5e-29
Smith-Waterman score: 531; 41.6% identity (75.8% similar) in 190 aa overlap (13-191:7-195)
10 20 30 40 50
pF1KE0 MASDHQTQAGKPQSLNP-KIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPW
.: .: :........:::. ::... ::.. : : : . :. : .: :
NP_001 MTLQCTKSAGPWKMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAW
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 VGYEQANCKGEQFVFEKGEYPRWDSW--TSSRRTDSLSSLRPIK-VDSQEHKIILYENPN
::.:.:. .:.:...:.:::: ::.: ... .. :.:.:: .. .. .. ..:. :
NP_001 VGFEHAGFQGQQYILERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQEN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 FTGKKMEIIDDDVPSFHAHGYQ-EKVSSVRVQSGTWVGYQYPGYRGLQYLLE----KGDY
: ::: :. .:: ::..: :.. ..:.: .:.::.:: :.:::::.::.:: .:::
NP_001 FLGKKGEL-SDDYPSLQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDY
120 130 140 150 160 170
180 190 200
pF1KE0 KDSSDFG--APHPQVQSVRRIRDMQWHQRGAFHPSN
: ..: :: ::::.:::.
NP_001 KHFREWGSHAPTFQVQSIRRIQQ
180 190
205 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 03:56:41 2016 done: Thu Nov 3 03:56:42 2016
Total Scan time: 6.020 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]