Result of FASTA (ccds) for
pFN21AE0501
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0501, 205 aa
1>>>pF1KE0501 205 - 205 aa - 205 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3226+/-0.000736; mu= 13.1409+/- 0.045
mean_var=60.9220+/-12.148, 0's: 0 Z-trim(108.7): 18 B-trim: 233 in 1/53
Lambda= 0.164319
statistics sampled from 10376 (10392) to 10376 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.704), E-opt: 0.2 (0.319), width: 16
Scan time: 2.140
The best scores are: opt bits E(32554)
CCDS13831.1 CRYBB2 gene_id:1415|Hs108|chr22 ( 205) 1442 349.9 6.6e-97
CCDS13830.1 CRYBB3 gene_id:1417|Hs108|chr22 ( 211) 838 206.7 8.6e-54
CCDS13840.1 CRYBB1 gene_id:1414|Hs108|chr22 ( 252) 805 198.9 2.3e-51
CCDS11249.1 CRYBA1 gene_id:1411|Hs108|chr17 ( 215) 579 145.3 2.7e-35
CCDS13841.1 CRYBA4 gene_id:1413|Hs108|chr22 ( 196) 512 129.4 1.5e-30
CCDS2429.1 CRYBA2 gene_id:1412|Hs108|chr2 ( 197) 478 121.3 4e-28
CCDS3275.1 CRYGS gene_id:1427|Hs108|chr3 ( 178) 406 104.2 5e-23
CCDS2380.1 CRYGB gene_id:1419|Hs108|chr2 ( 175) 398 102.3 1.8e-22
CCDS2379.1 CRYGC gene_id:1420|Hs108|chr2 ( 174) 388 100.0 9.4e-22
CCDS33367.1 CRYGA gene_id:1418|Hs108|chr2 ( 174) 380 98.1 3.5e-21
CCDS2378.1 CRYGD gene_id:1421|Hs108|chr2 ( 174) 348 90.5 6.7e-19
CCDS34506.1 AIM1 gene_id:202|Hs108|chr6 (1723) 321 84.5 4.2e-16
>>CCDS13831.1 CRYBB2 gene_id:1415|Hs108|chr22 (205 aa)
initn: 1442 init1: 1442 opt: 1442 Z-score: 1853.2 bits: 349.9 E(32554): 6.6e-97
Smith-Waterman score: 1442; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205)
10 20 30 40 50 60
pF1KE0 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 GYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 KMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 KMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAP
130 140 150 160 170 180
190 200
pF1KE0 HPQVQSVRRIRDMQWHQRGAFHPSN
:::::::::::::::::::::::::
CCDS13 HPQVQSVRRIRDMQWHQRGAFHPSN
190 200
>>CCDS13830.1 CRYBB3 gene_id:1417|Hs108|chr22 (211 aa)
initn: 965 init1: 805 opt: 838 Z-score: 1079.2 bits: 206.7 E(32554): 8.6e-54
Smith-Waterman score: 838; 53.8% identity (83.0% similar) in 212 aa overlap (1-205:1-211)
10 20 30 40 50
pF1KE0 MASDH----QTQAGKPQSL---NPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVL
:: .: :. ::: .. . :.:..: :::::. ::.. ::.: .. .::.::.
CCDS13 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 VQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYE
:..:::...:. .:::::.:::.:::::.:..:: .::: ::::...:: .::. :.:
CCDS13 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 NPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKD
:: :.:.::::.::::::. :::.:..:.:::. .::::::..::::: ::..:.:.:.
CCDS13 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
130 140 150 160 170 180
180 190 200
pF1KE0 SSDFGAPHPQVQSVRRIRDMQWHQRGAFHPSN
... : .::.::::::::..::.:: : ::.
CCDS13 WNEWDASQPQLQSVRRIRDQKWHKRGRF-PSS
190 200 210
>>CCDS13840.1 CRYBB1 gene_id:1414|Hs108|chr22 (252 aa)
initn: 934 init1: 788 opt: 805 Z-score: 1035.7 bits: 198.9 E(32554): 2.3e-51
Smith-Waterman score: 805; 55.9% identity (84.9% similar) in 186 aa overlap (16-201:58-243)
10 20 30 40
pF1KE0 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETG
: ....:: :::::. :..: : :: . :
CCDS13 PAGTSPSPGTTLAPTTVPITSAKAAELPPGNYRLVVFELENFQGRRAEFSGECSNLADRG
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE0 VEKAGSVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQ
... :..:.:::::..::.: .::.:..::::::::..:.:: :.: : :.::::.:.:
CCDS13 FDRVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTWSSSYRSDRLMSFRPIKMDAQ
90 100 110 120 130 140
110 120 130 140 150 160
pF1KE0 EHKIILYENPNFTGKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYL
:::: :.:. :: :. .:: ::.::. ..:....:.::.:.:::::::::::::: :::
CCDS13 EHKISLFEGANFKGNTIEIQGDDAPSLWVYGFSDRVGSVKVSSGTWVGYQYPGYRGYQYL
150 160 170 180 190 200
170 180 190 200
pF1KE0 LEKGDYKDSSDFGAPHPQVQSVRRIRDMQWHQRGAFHPSN
:: ::.. ...:: .::.::.::.:: ::: .:.:
CCDS13 LEPGDFRHWNEWGAFQPQMQSLRRLRDKQWHLEGSFPVLATEPPK
210 220 230 240 250
>>CCDS11249.1 CRYBA1 gene_id:1411|Hs108|chr17 (215 aa)
initn: 511 init1: 282 opt: 579 Z-score: 747.3 bits: 145.3 E(32554): 2.7e-35
Smith-Waterman score: 585; 46.1% identity (76.4% similar) in 191 aa overlap (12-191:25-214)
10 20 30 40
pF1KE0 MASDHQTQAGKPQSLNP-KIIIFEQENFQGHSHELNGPCPNLKETGV
: ::.: :: :..::::::. :... :::..: .
CCDS11 METQAEQQELETLPTTKMAQTNPTPGSLGPWKITIYDQENFQGKRMEFTSSCPNVSERSF
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 EKAGSVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSR--RTDSLSSLRPI-KVD
... :. :..: :.:::... :.::..:.:::::::.:..: . . : :.::: ...
CCDS11 DNVRSLKVESGAWIGYEHTSFCGQQFILERGEYPRWDAWSGSNAYHIERLMSFRPICSAN
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 SQEHKIILYENPNFTGKKMEIIDDDVPSFHAHG-YQEKVSSVRVQSGTWVGYQYPGYRGL
.: :. ..:. :: :.. :: .:: ::..: : ....:.:...:::.:: ::::::::
CCDS11 HKESKMTIFEKENFIGRQWEI-SDDYPSLQAMGWFNNEVGSMKIQSGAWVCYQYPGYRGY
130 140 150 160 170
170 180 190 200
pF1KE0 QYLLE----KGDYKDSSDFG--APHPQVQSVRRIRDMQWHQRGAFHPSN
::.:: :::: ..: : :.::.:::.
CCDS11 QYILECDHHGGDYKHWREWGSHAQTSQIQSIRRIQQ
180 190 200 210
>>CCDS13841.1 CRYBA4 gene_id:1413|Hs108|chr22 (196 aa)
initn: 477 init1: 237 opt: 512 Z-score: 662.0 bits: 129.4 E(32554): 1.5e-30
Smith-Waterman score: 531; 41.6% identity (75.8% similar) in 190 aa overlap (13-191:7-195)
10 20 30 40 50
pF1KE0 MASDHQTQAGKPQSLNP-KIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPW
.: .: :........:::. ::... ::.. : : : . :. : .: :
CCDS13 MTLQCTKSAGPWKMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAW
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 VGYEQANCKGEQFVFEKGEYPRWDSW--TSSRRTDSLSSLRPIK-VDSQEHKIILYENPN
::.:.:. .:.:...:.:::: ::.: ... .. :.:.:: .. .. .. ..:. :
CCDS13 VGFEHAGFQGQQYILERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQEN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 FTGKKMEIIDDDVPSFHAHGYQ-EKVSSVRVQSGTWVGYQYPGYRGLQYLLE----KGDY
: ::: :. .:: ::..: :.. ..:.: .:.::.:: :.:::::.::.:: .:::
CCDS13 FLGKKGEL-SDDYPSLQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDY
120 130 140 150 160 170
180 190 200
pF1KE0 KDSSDFG--APHPQVQSVRRIRDMQWHQRGAFHPSN
: ..: :: ::::.:::.
CCDS13 KHFREWGSHAPTFQVQSIRRIQQ
180 190
>>CCDS2429.1 CRYBA2 gene_id:1412|Hs108|chr2 (197 aa)
initn: 383 init1: 193 opt: 478 Z-score: 618.4 bits: 121.3 E(32554): 4e-28
Smith-Waterman score: 478; 37.8% identity (71.4% similar) in 196 aa overlap (7-191:2-196)
10 20 30 40 50
pF1KE0 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETG-VEKAGSVLVQAGPW
..: : .. ....:.:::. .: . : :. : : . .. :: :. : :
CCDS24 MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVW
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 VGYEQANCKGEQFVFEKGEYPRWDSWT--SSRRTDSLSSLRPIK-VDSQEHKIILYENPN
:..: . .:.::..:::.::::..:. ::. ...: :.::. .. .. .. :.:. :
CCDS24 VAFEYPDFQGQQFILEKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 FTGKKMEIIDDDVPSFHAHGYQEK-VSSVRVQSGTWVGYQYPGYRGLQYLLEK----GDY
: : :....:: ::. . :. : :.:..:.::.::.:::::::: ::.::. :..
CCDS24 FQGCKFDLVDD-YPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEF
120 130 140 150 160 170
180 190 200
pF1KE0 KDSSDFG--APHPQVQSVRRIRDMQWHQRGAFHPSN
...: : :.::.::..
CCDS24 CTYGELGTQAHTGQLQSIRRVQH
180 190
>>CCDS3275.1 CRYGS gene_id:1427|Hs108|chr3 (178 aa)
initn: 318 init1: 199 opt: 406 Z-score: 526.9 bits: 104.2 E(32554): 5e-23
Smith-Waterman score: 406; 35.6% identity (69.0% similar) in 174 aa overlap (18-190:7-176)
10 20 30 40 50 60
pF1KE0 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWV
:: ..:..::::. .. . : ... : . . .:. :..: :.
CCDS32 MSKTGTKITFYEDKNFQGRRYDCDCDCADFH-TYLSRCNSIKVEGGTWA
10 20 30 40
70 80 90 100 110
pF1KE0 GYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQ-EHKIILYENPNFTG
::. : : .... .::::... : . .: ::: : ... : ..:: ..:. .:.:
CCDS32 VYERPNFAGYMYILPQGEYPEYQRWMG--LNDRLSSCRAVHLPSGGQYKIQIFEKGDFSG
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE0 KKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGA
. .: .: ::. . ..... : .: :.:. :. :.::: ::::.: .:. :.::
CCDS32 QMYETTED-CPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGA
110 120 130 140 150 160
180 190 200
pF1KE0 PHPQVQSVRRIRDMQWHQRGAFHPSN
: ::: :::
CCDS32 ASPAVQSFRRIVE
170
>>CCDS2380.1 CRYGB gene_id:1419|Hs108|chr2 (175 aa)
initn: 414 init1: 193 opt: 398 Z-score: 516.8 bits: 102.3 E(32554): 1.8e-22
Smith-Waterman score: 398; 34.7% identity (67.0% similar) in 176 aa overlap (18-193:3-174)
10 20 30 40 50 60
pF1KE0 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWV
:: ..:.. :::.:.: . ::::. . .:. :..: :.
CCDS23 MGKITFYEDRAFQGRSYECTTDCPNLQPY-FSRCNSIRVESGCWM
10 20 30 40
70 80 90 100 110 120
pF1KE0 GYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGK
::. : .:.:. ...:::: ...: . .::. : : : ... .:. .. :.
CCDS23 IYERPNYQGHQYFLRRGEYPDYQQWMGL--SDSIRSCCLIPPHSGAYRMKIYDRDELRGQ
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 KMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAP
:. :: . : . . . .. :. : :.:. :..:.::: ::::. :.:. :.:::
CCDS23 MSELTDDCI-SVQDRFHLTEIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAP
110 120 130 140 150 160
190 200
pF1KE0 HPQVQSVRRIRDMQWHQRGAFHPSN
. .: :.::. :.
CCDS23 NAKVGSLRRVMDLY
170
>>CCDS2379.1 CRYGC gene_id:1420|Hs108|chr2 (174 aa)
initn: 385 init1: 164 opt: 388 Z-score: 504.0 bits: 100.0 E(32554): 9.4e-22
Smith-Waterman score: 388; 36.0% identity (66.9% similar) in 178 aa overlap (18-193:3-173)
10 20 30 40 50 60
pF1KE0 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWV
:: ..:.. :::.:.: . ::::. . .:. :..: :.
CCDS23 MGKITFYEDRAFQGRSYETTTDCPNLQPY-FSRCNSIRVESGCWM
10 20 30 40
70 80 90 100 110
pF1KE0 GYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSS--LRPIKVDSQEHKIILYENPNFT
::. : .:.:.....:::: ...: . .::. : : : :. :.. ::: .
CCDS23 LYERPNYQGQQYLLRRGEYPDYQQWMGL--SDSIRSCCLIPQTVS---HRLRLYEREDHK
50 60 70 80 90
120 130 140 150 160 170
pF1KE0 GKKMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFG
: ::. ..: ::.. . . .. :..: : :: :. :.::: ::::. .:. .:.:
CCDS23 GLMMEL-SEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWG
100 110 120 130 140 150
180 190 200
pF1KE0 APHPQVQSVRRIRDMQWHQRGAFHPSN
: .. :.::. :.
CCDS23 AMDAKAGSLRRVVDLY
160 170
>>CCDS33367.1 CRYGA gene_id:1418|Hs108|chr2 (174 aa)
initn: 385 init1: 173 opt: 380 Z-score: 493.7 bits: 98.1 E(32554): 3.5e-21
Smith-Waterman score: 380; 36.0% identity (65.2% similar) in 178 aa overlap (18-193:3-173)
10 20 30 40 50 60
pF1KE0 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWV
:: ..:...:::. .. . ::::. . . .:. :..: :.
CCDS33 MGKITFYEDRDFQGRCYNCISDCPNLR-VYFSRCNSIRVDSGCWM
10 20 30 40
70 80 90 100 110 120
pF1KE0 GYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGK
::. : .:.:. ...:.:: .. : . .::..: : : :. ::. ::: .. :
CCDS33 LYERPNYQGHQYFLRRGKYPDYQHWMGL--SDSVQSCRIIPHTSS-HKLRLYERDDYRGL
50 60 70 80 90 100
130 140 150 160 170
pF1KE0 KMEIIDDD--VPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFG
:. :: :: . .. :..: : :: :..:.::: ::::. :::. :.:
CCDS33 MSELTDDCACVPELF---RLPEIYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWG
110 120 130 140 150
180 190 200
pF1KE0 APHPQVQSVRRIRDMQWHQRGAFHPSN
. .: :.::. :.
CCDS33 GADAKVGSLRRVTDLY
160 170
205 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 03:56:41 2016 done: Thu Nov 3 03:56:41 2016
Total Scan time: 2.140 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]