Result of FASTA (omim) for
pFN21AE0430
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0430, 417 aa
1>>>pF1KE0430 417 - 417 aa - 417 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0370+/-0.000328; mu= 7.8540+/- 0.020
mean_var=262.9647+/-54.171, 0's: 0 Z-trim(123.6): 253 B-trim: 0 in 0/55
Lambda= 0.079091
statistics sampled from 43448 (43790) to 43448 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.806), E-opt: 0.2 (0.513), width: 16
Scan time: 9.910
The best scores are: opt bits E(85289)
NP_056328 (OMIM: 606217,607170) cysteine-rich with ( 420) 3077 363.9 4.3e-100
NP_001070883 (OMIM: 606217,607170) cysteine-rich w ( 420) 3077 363.9 4.3e-100
XP_016862664 (OMIM: 606217,607170) PREDICTED: cyst ( 420) 3073 363.4 5.9e-100
NP_001026887 (OMIM: 606217,607170) cysteine-rich w ( 422) 2654 315.6 1.5e-85
XP_011532410 (OMIM: 606217,607170) PREDICTED: cyst ( 426) 2652 315.4 1.7e-85
XP_005261795 (OMIM: 607171) PREDICTED: cysteine-ri ( 373) 1303 161.4 3.5e-39
NP_077300 (OMIM: 607171) cysteine-rich with EGF-li ( 353) 1299 160.9 4.6e-39
NP_001271247 (OMIM: 607171) cysteine-rich with EGF ( 321) 1057 133.2 8.9e-31
NP_001271246 (OMIM: 607171) cysteine-rich with EGF ( 325) 953 121.4 3.3e-27
XP_016884427 (OMIM: 607171) PREDICTED: cysteine-ri ( 252) 895 114.6 2.8e-25
NP_001128573 (OMIM: 607171) cysteine-rich with EGF ( 402) 819 106.2 1.5e-22
XP_005261794 (OMIM: 607171) PREDICTED: cysteine-ri ( 403) 819 106.2 1.5e-22
XP_011528674 (OMIM: 607171) PREDICTED: cysteine-ri ( 208) 809 104.7 2.2e-22
XP_006713128 (OMIM: 608560) PREDICTED: stabilin-1 (1619) 323 50.3 4e-05
XP_016861493 (OMIM: 608560) PREDICTED: stabilin-1 (1819) 323 50.4 4.3e-05
XP_016861492 (OMIM: 608560) PREDICTED: stabilin-1 (2555) 323 50.6 5.4e-05
XP_016861491 (OMIM: 608560) PREDICTED: stabilin-1 (2565) 323 50.6 5.4e-05
XP_005265031 (OMIM: 608560) PREDICTED: stabilin-1 (2569) 323 50.6 5.4e-05
NP_055951 (OMIM: 608560) stabilin-1 precursor [Hom (2570) 323 50.6 5.4e-05
XP_016861490 (OMIM: 608560) PREDICTED: stabilin-1 (2583) 323 50.6 5.4e-05
XP_016861489 (OMIM: 608560) PREDICTED: stabilin-1 (2589) 323 50.6 5.4e-05
XP_016861488 (OMIM: 608560) PREDICTED: stabilin-1 (2590) 323 50.6 5.4e-05
XP_005265030 (OMIM: 608560) PREDICTED: stabilin-1 (2595) 323 50.6 5.4e-05
XP_016861487 (OMIM: 608560) PREDICTED: stabilin-1 (2615) 323 50.6 5.5e-05
XP_011536844 (OMIM: 608561) PREDICTED: stabilin-2 (1238) 295 47.0 0.00031
XP_011536843 (OMIM: 608561) PREDICTED: stabilin-2 (1684) 295 47.2 0.00038
XP_011536841 (OMIM: 608561) PREDICTED: stabilin-2 (1994) 295 47.3 0.00042
XP_011536840 (OMIM: 608561) PREDICTED: stabilin-2 (2242) 295 47.3 0.00045
XP_016875074 (OMIM: 608561) PREDICTED: stabilin-2 (2246) 295 47.3 0.00045
XP_011536839 (OMIM: 608561) PREDICTED: stabilin-2 (2283) 295 47.3 0.00046
NP_060034 (OMIM: 608561) stabilin-2 precursor [Hom (2551) 295 47.4 0.00049
NP_001159605 (OMIM: 219000,607830) extracellular m (1976) 286 46.2 0.00085
XP_011525689 (OMIM: 604710,613177) PREDICTED: late (1421) 282 45.6 0.00095
XP_011525688 (OMIM: 604710,613177) PREDICTED: late (1436) 282 45.6 0.00096
XP_016882843 (OMIM: 604710,613177) PREDICTED: late (1438) 282 45.6 0.00096
XP_011525687 (OMIM: 604710,613177) PREDICTED: late (1478) 282 45.6 0.00097
XP_011525686 (OMIM: 604710,613177) PREDICTED: late (1480) 282 45.6 0.00098
XP_011525685 (OMIM: 604710,613177) PREDICTED: late (1522) 282 45.6 0.00099
XP_016882842 (OMIM: 604710,613177) PREDICTED: late (1549) 282 45.6 0.001
NP_001036010 (OMIM: 604710,613177) latent-transfor (1557) 282 45.6 0.001
NP_003564 (OMIM: 604710,613177) latent-transformin (1587) 282 45.7 0.001
XP_016882841 (OMIM: 604710,613177) PREDICTED: late (1591) 282 45.7 0.001
XP_011525682 (OMIM: 604710,613177) PREDICTED: late (1593) 282 45.7 0.001
XP_011525683 (OMIM: 604710,613177) PREDICTED: late (1593) 282 45.7 0.001
XP_011525681 (OMIM: 604710,613177) PREDICTED: late (1595) 282 45.7 0.001
XP_011525680 (OMIM: 604710,613177) PREDICTED: late (1611) 282 45.7 0.001
NP_001036009 (OMIM: 604710,613177) latent-transfor (1624) 282 45.7 0.001
XP_011525679 (OMIM: 604710,613177) PREDICTED: late (1635) 282 45.7 0.001
XP_011525678 (OMIM: 604710,613177) PREDICTED: late (1662) 282 45.7 0.0011
XP_006714379 (OMIM: 219000,607830) PREDICTED: extr (3936) 286 46.6 0.0013
>>NP_056328 (OMIM: 606217,607170) cysteine-rich with EGF (420 aa)
initn: 3077 init1: 3077 opt: 3077 Z-score: 1917.9 bits: 363.9 E(85289): 4.3e-100
Smith-Waterman score: 3077; 99.5% identity (99.5% similar) in 417 aa overlap (1-417:1-417)
10 20 30 40 50 60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEMTE
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_056 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTE
310 320 330 340 350 360
370 380 390 400 410
pF1KE0 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR
370 380 390 400 410 420
>>NP_001070883 (OMIM: 606217,607170) cysteine-rich with (420 aa)
initn: 3077 init1: 3077 opt: 3077 Z-score: 1917.9 bits: 363.9 E(85289): 4.3e-100
Smith-Waterman score: 3077; 99.5% identity (99.5% similar) in 417 aa overlap (1-417:1-417)
10 20 30 40 50 60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEMTE
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_001 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTE
310 320 330 340 350 360
370 380 390 400 410
pF1KE0 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR
370 380 390 400 410 420
>>XP_016862664 (OMIM: 606217,607170) PREDICTED: cysteine (420 aa)
initn: 3073 init1: 3073 opt: 3073 Z-score: 1915.4 bits: 363.4 E(85289): 5.9e-100
Smith-Waterman score: 3073; 99.3% identity (99.5% similar) in 417 aa overlap (1-417:1-417)
10 20 30 40 50 60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAPWPPKGLVPAMLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEMTE
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_016 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTE
310 320 330 340 350 360
370 380 390 400 410
pF1KE0 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR
370 380 390 400 410 420
>>NP_001026887 (OMIM: 606217,607170) cysteine-rich with (422 aa)
initn: 2647 init1: 2647 opt: 2654 Z-score: 1657.0 bits: 315.6 E(85289): 1.5e-85
Smith-Waterman score: 2654; 96.4% identity (98.3% similar) in 361 aa overlap (1-361:1-361)
10 20 30 40 50 60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEMTE
::::::::::::::::::::::::::::::::::: ::::::::::::: . .....:
NP_001 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPGAFPILTDLTP
310 320 330 340 350 360
370 380 390 400 410
pF1KE0 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI
.
NP_001 ETTRRWKLGSHPHSTYVKMKMQRDEATFPGLYGKQVAKLGSQSRQSDRGTRLIHSQQASS
370 380 390 400 410 420
>>XP_011532410 (OMIM: 606217,607170) PREDICTED: cysteine (426 aa)
initn: 2805 init1: 2646 opt: 2652 Z-score: 1655.8 bits: 315.4 E(85289): 1.7e-85
Smith-Waterman score: 2652; 96.7% identity (98.3% similar) in 361 aa overlap (1-360:1-361)
10 20 30 40 50 60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAPWPPKGLVPAMLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
250 260 270 280 290 300
310 320 330 340 350
pF1KE0 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESA-GFFSEMT
::::::::::::::::::::::::::::::::::: :::::::::::::... : : .:
XP_011 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPDAVLGAFPILT
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE0 EDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI
.
XP_011 DLTPETTRRWKLGSHPHSTYVKMKMQRDEATFPGLYGKQVAKLGSQSRQSDRGTRLIHSQ
370 380 390 400 410 420
>>XP_005261795 (OMIM: 607171) PREDICTED: cysteine-rich w (373 aa)
initn: 1200 init1: 1200 opt: 1303 Z-score: 824.5 bits: 161.4 E(85289): 3.5e-39
Smith-Waterman score: 1303; 48.8% identity (72.1% similar) in 330 aa overlap (26-353:13-337)
10 20 30 40 50 60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
:. : : :... .: ::: ::::::.::.:.
XP_005 MRLPRRAALGLLPLLLLLPPAPEAA--KKPTPCHRCRGLVDKFNQGM
10 20 30 40
70 80 90 100 110 120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
: . :::::::::::..::::..:: ::.:.:::.: .:::::...:: .:: .:.::
XP_005 VDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWW
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
.. .. ::::.:.: .::.:: ::.::.:: : ::..:::.: :.: :.:.: :.:
XP_005 LQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGS
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
: :. :: : : .: ::: . :: .: .:.:: : ::: . .: .:. ::.: .
XP_005 CRCHMGYQGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
:::.:::..: :.: ::: :..::: :..: ..:.:: : ::: ::.: :: .
XP_005 GACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREH
230 240 250 260 270 280
310 320 330 340 350
pF1KE0 SKCLDVDECET--EVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEM
..: ::::: ..: .:..: :: :.: :.: .: .. : :: : ::
XP_005 GQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVP---PAEAGEWHGC
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE0 TEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI
XP_005 PPHRLPSPGPQGLHVDWLLGLKSTQMVALRW
350 360 370
>>NP_077300 (OMIM: 607171) cysteine-rich with EGF-like d (353 aa)
initn: 1200 init1: 1200 opt: 1299 Z-score: 822.3 bits: 160.9 E(85289): 4.6e-39
Smith-Waterman score: 1299; 49.2% identity (73.2% similar) in 321 aa overlap (26-344:13-331)
10 20 30 40 50 60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
:. : : :... .: ::: ::::::.::.:.
NP_077 MRLPRRAALGLLPLLLLLPPAPEAAK--KPTPCHRCRGLVDKFNQGM
10 20 30 40
70 80 90 100 110 120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
: . :::::::::::..::::..:: ::.:.:::.: .:::::...:: .:: .:.::
NP_077 VDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWW
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
.. .. ::::.:.: .::.:: ::.::.:: : ::..:::.: :.: :.:.: :.:
NP_077 LQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGS
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
: :. :: : : .: ::: . :: .: .:.:: : ::: . .: .:. ::.: .
NP_077 CRCHMGYQGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
:::.:::..: :.: ::: :..::: :..: ..:.:: : ::: ::.: :: .
NP_077 GACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREH
230 240 250 260 270 280
310 320 330 340 350
pF1KE0 SKCLDVDECET--EVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEM
..: ::::: ..: .:..: :: :.: :.: .: .. : ::
NP_077 GQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPT
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE0 TEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI
NP_077 QLPSREDL
350
>>NP_001271247 (OMIM: 607171) cysteine-rich with EGF-lik (321 aa)
initn: 1093 init1: 1036 opt: 1057 Z-score: 673.6 bits: 133.2 E(85289): 8.9e-31
Smith-Waterman score: 1092; 44.9% identity (66.4% similar) in 321 aa overlap (26-344:13-299)
10 20 30 40 50 60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
:. : : :... .: ::: ::::::.::.:.
NP_001 MRLPRRAALGLLPLLLLLPPAPEAAK--KPTPCHRCRGLVDKFNQGM
10 20 30 40
70 80 90 100 110 120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
: . :::::::::::..::::..:: ::.:.:::.: .:::::...:: .:: .:.::
NP_001 VDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWW
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
.. .. ::::.:.: .::.:: ::.::.:: : ::..:::.: :.: :.:.: :.:
NP_001 LQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGS
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
: :. :: : : .: ::: . :: .: .:.:: : ::: . .: .:. ::.: .
NP_001 CRCHMGYQGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
:::.:::..: :.: ::: :..::: :.
NP_001 GACVDVDECAAEPPPCSAAQFCKNANGSYTCE----------------------------
230 240 250
310 320 330 340 350
pF1KE0 SKCLDVDECET--EVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEM
::::: ..: .:..: :: :.: :.: .: .. : ::
NP_001 ----DVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPT
260 270 280 290 300 310
360 370 380 390 400 410
pF1KE0 TEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI
NP_001 QLPSREDL
320
>>NP_001271246 (OMIM: 607171) cysteine-rich with EGF-lik (325 aa)
initn: 914 init1: 914 opt: 953 Z-score: 609.4 bits: 121.4 E(85289): 3.3e-27
Smith-Waterman score: 1118; 45.2% identity (66.7% similar) in 321 aa overlap (26-344:13-303)
10 20 30 40 50 60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
:. : : :... .: ::: ::::::.::.:.
NP_001 MRLPRRAALGLLPLLLLLPPAPEAAK--KPTPCHRCRGLVDKFNQGM
10 20 30 40
70 80 90 100 110 120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
: . :::::::::::..::::..:: ::.:.:::.: .:::::...:: .:: .:.::
NP_001 VDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWW
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
.. .. ::::.:.: .::.:: ::.::.:: : ::..:::.: :.: :.:.: :.:
NP_001 LQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGS
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
: :. :: : : .: ::: . :: .: .:.:: : ::: . .: .:. ::.:
NP_001 CRCHMGYQGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLD-
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
::: : .: ..:.:: : ::: ::.: :: .
NP_001 -----------EGA----------------CVECDSSCVGCTGEGPGNCKECISGYAREH
230 240 250
310 320 330 340 350
pF1KE0 SKCLDVDECET--EVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEM
..: ::::: ..: .:..: :: :.: :.: .: .. : ::
NP_001 GQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPT
260 270 280 290 300 310
360 370 380 390 400 410
pF1KE0 TEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI
NP_001 QLPSREDL
320
>>XP_016884427 (OMIM: 607171) PREDICTED: cysteine-rich w (252 aa)
initn: 798 init1: 798 opt: 895 Z-score: 574.9 bits: 114.6 E(85289): 2.8e-25
Smith-Waterman score: 895; 47.5% identity (70.3% similar) in 219 aa overlap (128-344:12-230)
100 110 120 130 140 150
pF1KE0 CSKSDFECHRLLELSEELVESWWFHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPG
::::.:.: .::.:: ::.::.:: : :
XP_016 MFSSILRKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQG
10 20 30 40
160 170 180 190 200 210
pF1KE0 GTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGP
:..:::.: :.: :.:.: :.: : :. :: : : .: ::: . :: .: .:.::
XP_016 GSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGYFSSLRNETHSICTACDES
50 60 70 80 90 100
220 230 240 250 260 270
pF1KE0 CARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKA
: ::: . .: .:. ::.: . :::.:::..: :.: ::: :..::: :..: ..
XP_016 CKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSS
110 120 130 140 150 160
280 290 300 310 320 330
pF1KE0 CLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECET--EVCPGENKQCENTEGGYRCICAEG
:.:: : ::: ::.: :: . ..: ::::: ..: .:..: :: :.: :.: .:
XP_016 CVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDG
170 180 190 200 210 220
340 350 360 370 380 390
pF1KE0 CKQMEGICVKEQIPESAGFFSEMTEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIG
.. : ::
XP_016 FEETEDACVPPAEAEATEGESPTQLPSREDL
230 240 250
417 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 09:45:58 2016 done: Thu Nov 3 09:45:59 2016
Total Scan time: 9.910 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]