Result of FASTA (omim) for
pFN21AB6129
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6129, 587 aa
1>>>pF1KB6129 587 - 587 aa - 587 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5307+/-0.000395; mu= 18.1375+/- 0.024
mean_var=80.3943+/-16.439, 0's: 0 Z-trim(112.9): 25 B-trim: 570 in 1/52
Lambda= 0.143041
statistics sampled from 21966 (21983) to 21966 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.626), E-opt: 0.2 (0.258), width: 16
Scan time: 10.450
The best scores are: opt bits E(85289)
NP_057492 (OMIM: 608200) CDK5 regulatory subunit-a ( 587) 3869 808.6 0
NP_001265096 (OMIM: 608200) CDK5 regulatory subuni ( 586) 3851 804.9 0
NP_057166 (OMIM: 608200) CDK5 regulatory subunit-a ( 588) 3577 748.3 1.6e-215
NP_001265098 (OMIM: 608200) CDK5 regulatory subuni ( 560) 3376 706.8 4.7e-203
XP_011527159 (OMIM: 608200) PREDICTED: CDK5 regula ( 477) 3106 651.1 2.4e-186
XP_011527161 (OMIM: 608200) PREDICTED: CDK5 regula ( 460) 2943 617.4 3.2e-176
XP_011527160 (OMIM: 608200) PREDICTED: CDK5 regula ( 460) 2943 617.4 3.2e-176
XP_011527158 (OMIM: 608200) PREDICTED: CDK5 regula ( 483) 2882 604.8 2e-172
XP_016883365 (OMIM: 608200) PREDICTED: CDK5 regula ( 333) 2198 463.6 4.7e-130
XP_011527162 (OMIM: 608200) PREDICTED: CDK5 regula ( 333) 2198 463.6 4.7e-130
XP_016883366 (OMIM: 608200) PREDICTED: CDK5 regula ( 321) 1947 411.8 1.8e-114
NP_001265097 (OMIM: 608200) CDK5 regulatory subuni ( 510) 1938 410.1 9.3e-114
NP_060244 (OMIM: 125853,611259) threonylcarbamoyla ( 579) 258 63.4 2.4e-09
XP_016866476 (OMIM: 125853,611259) PREDICTED: thre ( 293) 246 60.7 7.7e-09
XP_016866475 (OMIM: 125853,611259) PREDICTED: thre ( 435) 246 60.8 1.1e-08
XP_011513021 (OMIM: 125853,611259) PREDICTED: thre ( 443) 246 60.8 1.1e-08
XP_011513020 (OMIM: 125853,611259) PREDICTED: thre ( 558) 231 57.8 1.1e-07
>>NP_057492 (OMIM: 608200) CDK5 regulatory subunit-assoc (587 aa)
initn: 3869 init1: 3869 opt: 3869 Z-score: 4316.1 bits: 808.6 E(85289): 0
Smith-Waterman score: 3869; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KB6 MHPLQCVLQVQRSLGWGPLASVSWLSLRMCRAHSSLSSTMCPSPERQEDGARKDFSSRLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MHPLQCVLQVQRSLGWGPLASVSWLSLRMCRAHSSLSSTMCPSPERQEDGARKDFSSRLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AGPTFQHFLKSASAPQEKLSSEVEDPPPYLMMDELLGRQRKVYLETYGCQMNVNDTEIAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 AGPTFQHFLKSASAPQEKLSSEVEDPPPYLMMDELLGRQRKVYLETYGCQMNVNDTEIAW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SILQKSGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKALKTRRPRSRVPLRIGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SILQKSGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKALKTRRPRSRVPLRIGI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAESGQQAANVLLSLDETYADVMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAESGQQAANVLLSLDETYADVMP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 VQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIASILEEVKKLSEQGLKEVTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIASILEEVKKLSEQGLKEVTLL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 GQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLLDQVSRVDPEMRIRFTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLLDQVSRVDPEMRIRFTS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 PHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYSREAYVELVHHIRESIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYSREAYVELVHHIRESIP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 GVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQKTRAYHRLKDDVPEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQKTRAYHRLKDDVPEEV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 KLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSATDLCGRNDGNLKVIFPDAEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSATDLCGRNDGNLKVIFPDAEM
490 500 510 520 530 540
550 560 570 580
pF1KB6 EDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSSAYC
:::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSSAYC
550 560 570 580
>>NP_001265096 (OMIM: 608200) CDK5 regulatory subunit-as (586 aa)
initn: 3072 init1: 3072 opt: 3851 Z-score: 4296.0 bits: 804.9 E(85289): 0
Smith-Waterman score: 3851; 99.8% identity (99.8% similar) in 587 aa overlap (1-587:1-586)
10 20 30 40 50 60
pF1KB6 MHPLQCVLQVQRSLGWGPLASVSWLSLRMCRAHSSLSSTMCPSPERQEDGARKDFSSRLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MHPLQCVLQVQRSLGWGPLASVSWLSLRMCRAHSSLSSTMCPSPERQEDGARKDFSSRLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AGPTFQHFLKSASAPQEKLSSEVEDPPPYLMMDELLGRQRKVYLETYGCQMNVNDTEIAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGPTFQHFLKSASAPQEKLSSEVEDPPPYLMMDELLGRQRKVYLETYGCQMNVNDTEIAW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SILQKSGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKALKTRRPRSRVPLRIGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SILQKSGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKALKTRRPRSRVPLRIGI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAESGQQAANVLLSLDETYADVMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAESGQQAANVLLSLDETYADVMP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 VQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIASILEEVKKLSEQGLKEVTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIASILEEVKKLSEQGLKEVTLL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 GQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLLDQVSRVDPEMRIRFTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLLDQVSRVDPEMRIRFTS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 PHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYSREAYVELVHHIRESIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYSREAYVELVHHIRESIP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 GVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQKTRAYHRLKDDVPEEV
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
NP_001 GVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQ-TRAYHRLKDDVPEEV
430 440 450 460 470
490 500 510 520 530 540
pF1KB6 KLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSATDLCGRNDGNLKVIFPDAEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSATDLCGRNDGNLKVIFPDAEM
480 490 500 510 520 530
550 560 570 580
pF1KB6 EDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSSAYC
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSSAYC
540 550 560 570 580
>>NP_057166 (OMIM: 608200) CDK5 regulatory subunit-assoc (588 aa)
initn: 3577 init1: 3577 opt: 3577 Z-score: 3990.4 bits: 748.3 E(85289): 1.6e-215
Smith-Waterman score: 3577; 99.8% identity (99.8% similar) in 547 aa overlap (41-587:42-588)
20 30 40 50 60 70
pF1KB6 QRSLGWGPLASVSWLSLRMCRAHSSLSSTMCPSPERQEDGARKDFSSRLAAGPTFQHFLK
: ::::::::::::::::::::::::::::
NP_057 SLVYERSGGPVRGSDLPAELTLRDPGHCCCCGSPERQEDGARKDFSSRLAAGPTFQHFLK
20 30 40 50 60 70
80 90 100 110 120 130
pF1KB6 SASAPQEKLSSEVEDPPPYLMMDELLGRQRKVYLETYGCQMNVNDTEIAWSILQKSGYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SASAPQEKLSSEVEDPPPYLMMDELLGRQRKVYLETYGCQMNVNDTEIAWSILQKSGYLR
80 90 100 110 120 130
140 150 160 170 180 190
pF1KB6 TSNLQEADVILLVTCSIREKAEQTIWNRLHQLKALKTRRPRSRVPLRIGILGCMAERLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 TSNLQEADVILLVTCSIREKAEQTIWNRLHQLKALKTRRPRSRVPLRIGILGCMAERLKE
140 150 160 170 180 190
200 210 220 230 240 250
pF1KB6 EILNREKMVDILAGPDAYRDLPRLLAVAESGQQAANVLLSLDETYADVMPVQTSASATSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EILNREKMVDILAGPDAYRDLPRLLAVAESGQQAANVLLSLDETYADVMPVQTSASATSA
200 210 220 230 240 250
260 270 280 290 300 310
pF1KB6 FVSIMRGCDNMCSYCIVPFTRGRERSRPIASILEEVKKLSEQGLKEVTLLGQNVNSFRDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FVSIMRGCDNMCSYCIVPFTRGRERSRPIASILEEVKKLSEQGLKEVTLLGQNVNSFRDN
260 270 280 290 300 310
320 330 340 350 360 370
pF1KB6 SEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLLDQVSRVDPEMRIRFTSPHPKDFPDEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLLDQVSRVDPEMRIRFTSPHPKDFPDEV
320 330 340 350 360 370
380 390 400 410 420 430
pF1KB6 LQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYSREAYVELVHHIRESIPGVSLSSDFIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYSREAYVELVHHIRESIPGVSLSSDFIA
380 390 400 410 420 430
440 450 460 470 480 490
pF1KB6 GFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQKTRAYHRLKDDVPEEVKLRRLEELIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQKTRAYHRLKDDVPEEVKLRRLEELIT
440 450 460 470 480 490
500 510 520 530 540 550
pF1KB6 IFREEATKANQTSVGCTQLVLVEGLSKRSATDLCGRNDGNLKVIFPDAEMEDVNNPGLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 IFREEATKANQTSVGCTQLVLVEGLSKRSATDLCGRNDGNLKVIFPDAEMEDVNNPGLRV
500 510 520 530 540 550
560 570 580
pF1KB6 RAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSSAYC
:::::::::::::::::::::::::::::::::::::
NP_057 RAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSSAYC
560 570 580
>>NP_001265098 (OMIM: 608200) CDK5 regulatory subunit-as (560 aa)
initn: 3376 init1: 3376 opt: 3376 Z-score: 3766.5 bits: 706.8 E(85289): 4.7e-203
Smith-Waterman score: 3376; 100.0% identity (100.0% similar) in 517 aa overlap (71-587:44-560)
50 60 70 80 90 100
pF1KB6 CPSPERQEDGARKDFSSRLAAGPTFQHFLKSASAPQEKLSSEVEDPPPYLMMDELLGRQR
::::::::::::::::::::::::::::::
NP_001 VYERSGGPVRGSDLPAELTLRDPGHCCCCGSASAPQEKLSSEVEDPPPYLMMDELLGRQR
20 30 40 50 60 70
110 120 130 140 150 160
pF1KB6 KVYLETYGCQMNVNDTEIAWSILQKSGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVYLETYGCQMNVNDTEIAWSILQKSGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLH
80 90 100 110 120 130
170 180 190 200 210 220
pF1KB6 QLKALKTRRPRSRVPLRIGILGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLKALKTRRPRSRVPLRIGILGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAES
140 150 160 170 180 190
230 240 250 260 270 280
pF1KB6 GQQAANVLLSLDETYADVMPVQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQQAANVLLSLDETYADVMPVQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIA
200 210 220 230 240 250
290 300 310 320 330 340
pF1KB6 SILEEVKKLSEQGLKEVTLLGQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SILEEVKKLSEQGLKEVTLLGQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRF
260 270 280 290 300 310
350 360 370 380 390 400
pF1KB6 AHLLDQVSRVDPEMRIRFTSPHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHLLDQVSRVDPEMRIRFTSPHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMR
320 330 340 350 360 370
410 420 430 440 450 460
pF1KB6 RGYSREAYVELVHHIRESIPGVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGYSREAYVELVHHIRESIPGVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAY
380 390 400 410 420 430
470 480 490 500 510 520
pF1KB6 SMRQKTRAYHRLKDDVPEEVKLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMRQKTRAYHRLKDDVPEEVKLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSA
440 450 460 470 480 490
530 540 550 560 570 580
pF1KB6 TDLCGRNDGNLKVIFPDAEMEDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDLCGRNDGNLKVIFPDAEMEDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTL
500 510 520 530 540 550
pF1KB6 RDSSAYC
:::::::
NP_001 RDSSAYC
560
>>XP_011527159 (OMIM: 608200) PREDICTED: CDK5 regulatory (477 aa)
initn: 3106 init1: 3106 opt: 3106 Z-score: 3466.4 bits: 651.1 E(85289): 2.4e-186
Smith-Waterman score: 3106; 100.0% identity (100.0% similar) in 477 aa overlap (111-587:1-477)
90 100 110 120 130 140
pF1KB6 SEVEDPPPYLMMDELLGRQRKVYLETYGCQMNVNDTEIAWSILQKSGYLRTSNLQEADVI
::::::::::::::::::::::::::::::
XP_011 MNVNDTEIAWSILQKSGYLRTSNLQEADVI
10 20 30
150 160 170 180 190 200
pF1KB6 LLVTCSIREKAEQTIWNRLHQLKALKTRRPRSRVPLRIGILGCMAERLKEEILNREKMVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVTCSIREKAEQTIWNRLHQLKALKTRRPRSRVPLRIGILGCMAERLKEEILNREKMVD
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB6 ILAGPDAYRDLPRLLAVAESGQQAANVLLSLDETYADVMPVQTSASATSAFVSIMRGCDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILAGPDAYRDLPRLLAVAESGQQAANVLLSLDETYADVMPVQTSASATSAFVSIMRGCDN
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB6 MCSYCIVPFTRGRERSRPIASILEEVKKLSEQGLKEVTLLGQNVNSFRDNSEVQFNSAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MCSYCIVPFTRGRERSRPIASILEEVKKLSEQGLKEVTLLGQNVNSFRDNSEVQFNSAVP
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB6 TNLSRGFTTNYKTKQGGLRFAHLLDQVSRVDPEMRIRFTSPHPKDFPDEVLQLIHERDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNLSRGFTTNYKTKQGGLRFAHLLDQVSRVDPEMRIRFTSPHPKDFPDEVLQLIHERDNI
220 230 240 250 260 270
390 400 410 420 430 440
pF1KB6 CKQIHLPAQSGSSRVLEAMRRGYSREAYVELVHHIRESIPGVSLSSDFIAGFCGETEEDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKQIHLPAQSGSSRVLEAMRRGYSREAYVELVHHIRESIPGVSLSSDFIAGFCGETEEDH
280 290 300 310 320 330
450 460 470 480 490 500
pF1KB6 VQTVSLLREVQYNMGFLFAYSMRQKTRAYHRLKDDVPEEVKLRRLEELITIFREEATKAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQTVSLLREVQYNMGFLFAYSMRQKTRAYHRLKDDVPEEVKLRRLEELITIFREEATKAN
340 350 360 370 380 390
510 520 530 540 550 560
pF1KB6 QTSVGCTQLVLVEGLSKRSATDLCGRNDGNLKVIFPDAEMEDVNNPGLRVRAQPGDYVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTSVGCTQLVLVEGLSKRSATDLCGRNDGNLKVIFPDAEMEDVNNPGLRVRAQPGDYVLV
400 410 420 430 440 450
570 580
pF1KB6 KITSASSQTLRGHVLCRTTLRDSSAYC
:::::::::::::::::::::::::::
XP_011 KITSASSQTLRGHVLCRTTLRDSSAYC
460 470
>>XP_011527161 (OMIM: 608200) PREDICTED: CDK5 regulatory (460 aa)
initn: 2943 init1: 2943 opt: 2943 Z-score: 3284.8 bits: 617.4 E(85289): 3.2e-176
Smith-Waterman score: 2943; 99.6% identity (100.0% similar) in 453 aa overlap (135-587:8-460)
110 120 130 140 150 160
pF1KB6 ETYGCQMNVNDTEIAWSILQKSGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKA
..::::::::::::::::::::::::::::
XP_011 MNFLEGREKADVILLVTCSIREKAEQTIWNRLHQLKA
10 20 30
170 180 190 200 210 220
pF1KB6 LKTRRPRSRVPLRIGILGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAESGQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKTRRPRSRVPLRIGILGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAESGQQA
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB6 ANVLLSLDETYADVMPVQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIASILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANVLLSLDETYADVMPVQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIASILE
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB6 EVKKLSEQGLKEVTLLGQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVKKLSEQGLKEVTLLGQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLL
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB6 DQVSRVDPEMRIRFTSPHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQVSRVDPEMRIRFTSPHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYS
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB6 REAYVELVHHIRESIPGVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REAYVELVHHIRESIPGVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQ
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB6 KTRAYHRLKDDVPEEVKLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSATDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTRAYHRLKDDVPEEVKLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSATDLC
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB6 GRNDGNLKVIFPDAEMEDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRNDGNLKVIFPDAEMEDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSS
400 410 420 430 440 450
pF1KB6 AYC
:::
XP_011 AYC
460
>>XP_011527160 (OMIM: 608200) PREDICTED: CDK5 regulatory (460 aa)
initn: 2943 init1: 2943 opt: 2943 Z-score: 3284.8 bits: 617.4 E(85289): 3.2e-176
Smith-Waterman score: 2943; 99.6% identity (100.0% similar) in 453 aa overlap (135-587:8-460)
110 120 130 140 150 160
pF1KB6 ETYGCQMNVNDTEIAWSILQKSGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKA
..::::::::::::::::::::::::::::
XP_011 MNFLEGREKADVILLVTCSIREKAEQTIWNRLHQLKA
10 20 30
170 180 190 200 210 220
pF1KB6 LKTRRPRSRVPLRIGILGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAESGQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKTRRPRSRVPLRIGILGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAESGQQA
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB6 ANVLLSLDETYADVMPVQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIASILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANVLLSLDETYADVMPVQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIASILE
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB6 EVKKLSEQGLKEVTLLGQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVKKLSEQGLKEVTLLGQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLL
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB6 DQVSRVDPEMRIRFTSPHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQVSRVDPEMRIRFTSPHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYS
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB6 REAYVELVHHIRESIPGVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REAYVELVHHIRESIPGVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQ
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB6 KTRAYHRLKDDVPEEVKLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSATDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTRAYHRLKDDVPEEVKLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSATDLC
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB6 GRNDGNLKVIFPDAEMEDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRNDGNLKVIFPDAEMEDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSS
400 410 420 430 440 450
pF1KB6 AYC
:::
XP_011 AYC
460
>>XP_011527158 (OMIM: 608200) PREDICTED: CDK5 regulatory (483 aa)
initn: 2874 init1: 2874 opt: 2882 Z-score: 3216.5 bits: 604.8 E(85289): 2e-172
Smith-Waterman score: 2882; 99.5% identity (99.5% similar) in 443 aa overlap (145-587:41-483)
120 130 140 150 160 170
pF1KB6 DTEIAWSILQKSGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKALKTRRPRSRV
: :::::::::::::::::::::::::::
XP_011 KSLVYERSGGPVRGSDLPAELTLRDPGHCCCCGREKAEQTIWNRLHQLKALKTRRPRSRV
20 30 40 50 60 70
180 190 200 210 220 230
pF1KB6 PLRIGILGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAESGQQAANVLLSLDET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLRIGILGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAESGQQAANVLLSLDET
80 90 100 110 120 130
240 250 260 270 280 290
pF1KB6 YADVMPVQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIASILEEVKKLSEQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YADVMPVQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIASILEEVKKLSEQGL
140 150 160 170 180 190
300 310 320 330 340 350
pF1KB6 KEVTLLGQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLLDQVSRVDPEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEVTLLGQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLLDQVSRVDPEM
200 210 220 230 240 250
360 370 380 390 400 410
pF1KB6 RIRFTSPHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYSREAYVELVHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIRFTSPHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYSREAYVELVHH
260 270 280 290 300 310
420 430 440 450 460 470
pF1KB6 IRESIPGVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQKTRAYHRLKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRESIPGVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQKTRAYHRLKD
320 330 340 350 360 370
480 490 500 510 520 530
pF1KB6 DVPEEVKLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSATDLCGRNDGNLKVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVPEEVKLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSATDLCGRNDGNLKVI
380 390 400 410 420 430
540 550 560 570 580
pF1KB6 FPDAEMEDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSSAYC
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPDAEMEDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSSAYC
440 450 460 470 480
>>XP_016883365 (OMIM: 608200) PREDICTED: CDK5 regulatory (333 aa)
initn: 2198 init1: 2198 opt: 2198 Z-score: 2455.9 bits: 463.6 E(85289): 4.7e-130
Smith-Waterman score: 2198; 100.0% identity (100.0% similar) in 333 aa overlap (255-587:1-333)
230 240 250 260 270 280
pF1KB6 ANVLLSLDETYADVMPVQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIASILE
::::::::::::::::::::::::::::::
XP_016 MRGCDNMCSYCIVPFTRGRERSRPIASILE
10 20 30
290 300 310 320 330 340
pF1KB6 EVKKLSEQGLKEVTLLGQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVKKLSEQGLKEVTLLGQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLL
40 50 60 70 80 90
350 360 370 380 390 400
pF1KB6 DQVSRVDPEMRIRFTSPHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQVSRVDPEMRIRFTSPHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYS
100 110 120 130 140 150
410 420 430 440 450 460
pF1KB6 REAYVELVHHIRESIPGVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REAYVELVHHIRESIPGVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQ
160 170 180 190 200 210
470 480 490 500 510 520
pF1KB6 KTRAYHRLKDDVPEEVKLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSATDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTRAYHRLKDDVPEEVKLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSATDLC
220 230 240 250 260 270
530 540 550 560 570 580
pF1KB6 GRNDGNLKVIFPDAEMEDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRNDGNLKVIFPDAEMEDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSS
280 290 300 310 320 330
pF1KB6 AYC
:::
XP_016 AYC
>>XP_011527162 (OMIM: 608200) PREDICTED: CDK5 regulatory (333 aa)
initn: 2198 init1: 2198 opt: 2198 Z-score: 2455.9 bits: 463.6 E(85289): 4.7e-130
Smith-Waterman score: 2198; 100.0% identity (100.0% similar) in 333 aa overlap (255-587:1-333)
230 240 250 260 270 280
pF1KB6 ANVLLSLDETYADVMPVQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIASILE
::::::::::::::::::::::::::::::
XP_011 MRGCDNMCSYCIVPFTRGRERSRPIASILE
10 20 30
290 300 310 320 330 340
pF1KB6 EVKKLSEQGLKEVTLLGQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVKKLSEQGLKEVTLLGQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLL
40 50 60 70 80 90
350 360 370 380 390 400
pF1KB6 DQVSRVDPEMRIRFTSPHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQVSRVDPEMRIRFTSPHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYS
100 110 120 130 140 150
410 420 430 440 450 460
pF1KB6 REAYVELVHHIRESIPGVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REAYVELVHHIRESIPGVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQ
160 170 180 190 200 210
470 480 490 500 510 520
pF1KB6 KTRAYHRLKDDVPEEVKLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSATDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTRAYHRLKDDVPEEVKLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSATDLC
220 230 240 250 260 270
530 540 550 560 570 580
pF1KB6 GRNDGNLKVIFPDAEMEDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRNDGNLKVIFPDAEMEDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSS
280 290 300 310 320 330
pF1KB6 AYC
:::
XP_011 AYC
587 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 21:47:42 2016 done: Fri Nov 4 21:47:44 2016
Total Scan time: 10.450 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]