Result of FASTA (omim) for
pFN21AE0210
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0210, 270 aa
1>>>pF1KE0210 270 - 270 aa - 270 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2781+/-0.00036; mu= 14.9149+/- 0.022
mean_var=64.5556+/-13.041, 0's: 0 Z-trim(112.8): 8 B-trim: 46 in 1/53
Lambda= 0.159627
statistics sampled from 21920 (21928) to 21920 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.642), E-opt: 0.2 (0.257), width: 16
Scan time: 7.330
The best scores are: opt bits E(85289)
NP_065108 (OMIM: 610775) fructose-2,6-bisphosphata ( 270) 1770 416.3 2.9e-116
NP_001715 (OMIM: 222800,613896) bisphosphoglycerat ( 259) 145 42.1 0.0013
NP_001280014 (OMIM: 222800,613896) bisphosphoglyce ( 259) 145 42.1 0.0013
XP_011514829 (OMIM: 222800,613896) PREDICTED: bisp ( 259) 145 42.1 0.0013
NP_954655 (OMIM: 222800,613896) bisphosphoglycerat ( 259) 145 42.1 0.0013
NP_000281 (OMIM: 261670,612931) phosphoglycerate m ( 253) 140 40.9 0.0028
>>NP_065108 (OMIM: 610775) fructose-2,6-bisphosphatase T (270 aa)
initn: 1770 init1: 1770 opt: 1770 Z-score: 2208.2 bits: 416.3 E(85289): 2.9e-116
Smith-Waterman score: 1770; 100.0% identity (100.0% similar) in 270 aa overlap (1-270:1-270)
10 20 30 40 50 60
pF1KE0 MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 RTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 GGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 NSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 NSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFII
190 200 210 220 230 240
250 260 270
pF1KE0 NFEEGREVKPTVQCICMNLQDHLNGLTETR
::::::::::::::::::::::::::::::
NP_065 NFEEGREVKPTVQCICMNLQDHLNGLTETR
250 260 270
>>NP_001715 (OMIM: 222800,613896) bisphosphoglycerate mu (259 aa)
initn: 98 init1: 67 opt: 145 Z-score: 186.0 bits: 42.1 E(85289): 0.0013
Smith-Waterman score: 154; 24.8% identity (53.1% similar) in 258 aa overlap (1-250:1-231)
10 20 30 40 50
pF1KE0 MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLN--NVKFTHAFSSD
:... : ..:::: .:::. . . ::. :. :...: : :. : .: .:.:
NP_001 MSKYKLIMLRHGEGAWNKENRFCSW-VDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSV
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LMRTKQTMHGILERSKFCKD-MTVKYDSRLRERKYGVVEG-----KALSELRAMAKAARE
: :. .: ::: .. .. . :. . :: ::.::.. : ::.. . ... :.
NP_001 LNRSIHTAWLILE--ELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 ECPVFTPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPL
: :: :. . : .:.. : :: . :. :. : ...:
NP_001 SYNVTPPPIEESHPYYQEIYNDRRYKVCDVPL---DQLPR------SESLKDVLERLLPY
120 130 140 150 160
180 190 200 210 220 230
pF1KE0 GKNHSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPN
.. .. . . : ..:. .:: :.:. .. .: .....:
NP_001 WNE---RIAPEV-LRG--KTILISAHGNSSRALLKHL---------EGISDEDIINITLP
170 180 190 200 210
240 250 260 270
pF1KE0 TGMSLFIINFEEGREVKPTVQCICMNLQDHLNGLTETR
::. ... :. : : :
NP_001 TGVPILLELDENLRAVGPHQFLGDQEAIQAAIKKVEDQGKVKQAKK
220 230 240 250
>>NP_001280014 (OMIM: 222800,613896) bisphosphoglycerate (259 aa)
initn: 98 init1: 67 opt: 145 Z-score: 186.0 bits: 42.1 E(85289): 0.0013
Smith-Waterman score: 154; 24.8% identity (53.1% similar) in 258 aa overlap (1-250:1-231)
10 20 30 40 50
pF1KE0 MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLN--NVKFTHAFSSD
:... : ..:::: .:::. . . ::. :. :...: : :. : .: .:.:
NP_001 MSKYKLIMLRHGEGAWNKENRFCSW-VDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSV
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LMRTKQTMHGILERSKFCKD-MTVKYDSRLRERKYGVVEG-----KALSELRAMAKAARE
: :. .: ::: .. .. . :. . :: ::.::.. : ::.. . ... :.
NP_001 LNRSIHTAWLILE--ELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 ECPVFTPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPL
: :: :. . : .:.. : :: . :. :. : ...:
NP_001 SYNVTPPPIEESHPYYQEIYNDRRYKVCDVPL---DQLPR------SESLKDVLERLLPY
120 130 140 150 160
180 190 200 210 220 230
pF1KE0 GKNHSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPN
.. .. . . : ..:. .:: :.:. .. .: .....:
NP_001 WNE---RIAPEV-LRG--KTILISAHGNSSRALLKHL---------EGISDEDIINITLP
170 180 190 200 210
240 250 260 270
pF1KE0 TGMSLFIINFEEGREVKPTVQCICMNLQDHLNGLTETR
::. ... :. : : :
NP_001 TGVPILLELDENLRAVGPHQFLGDQEAIQAAIKKVEDQGKVKQAKK
220 230 240 250
>>XP_011514829 (OMIM: 222800,613896) PREDICTED: bisphosp (259 aa)
initn: 98 init1: 67 opt: 145 Z-score: 186.0 bits: 42.1 E(85289): 0.0013
Smith-Waterman score: 154; 24.8% identity (53.1% similar) in 258 aa overlap (1-250:1-231)
10 20 30 40 50
pF1KE0 MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLN--NVKFTHAFSSD
:... : ..:::: .:::. . . ::. :. :...: : :. : .: .:.:
XP_011 MSKYKLIMLRHGEGAWNKENRFCSW-VDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSV
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LMRTKQTMHGILERSKFCKD-MTVKYDSRLRERKYGVVEG-----KALSELRAMAKAARE
: :. .: ::: .. .. . :. . :: ::.::.. : ::.. . ... :.
XP_011 LNRSIHTAWLILE--ELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 ECPVFTPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPL
: :: :. . : .:.. : :: . :. :. : ...:
XP_011 SYNVTPPPIEESHPYYQEIYNDRRYKVCDVPL---DQLPR------SESLKDVLERLLPY
120 130 140 150 160
180 190 200 210 220 230
pF1KE0 GKNHSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPN
.. .. . . : ..:. .:: :.:. .. .: .....:
XP_011 WNE---RIAPEV-LRG--KTILISAHGNSSRALLKHL---------EGISDEDIINITLP
170 180 190 200 210
240 250 260 270
pF1KE0 TGMSLFIINFEEGREVKPTVQCICMNLQDHLNGLTETR
::. ... :. : : :
XP_011 TGVPILLELDENLRAVGPHQFLGDQEAIQAAIKKVEDQGKVKQAKK
220 230 240 250
>>NP_954655 (OMIM: 222800,613896) bisphosphoglycerate mu (259 aa)
initn: 98 init1: 67 opt: 145 Z-score: 186.0 bits: 42.1 E(85289): 0.0013
Smith-Waterman score: 154; 24.8% identity (53.1% similar) in 258 aa overlap (1-250:1-231)
10 20 30 40 50
pF1KE0 MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLN--NVKFTHAFSSD
:... : ..:::: .:::. . . ::. :. :...: : :. : .: .:.:
NP_954 MSKYKLIMLRHGEGAWNKENRFCSW-VDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSV
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LMRTKQTMHGILERSKFCKD-MTVKYDSRLRERKYGVVEG-----KALSELRAMAKAARE
: :. .: ::: .. .. . :. . :: ::.::.. : ::.. . ... :.
NP_954 LNRSIHTAWLILE--ELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 ECPVFTPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPL
: :: :. . : .:.. : :: . :. :. : ...:
NP_954 SYNVTPPPIEESHPYYQEIYNDRRYKVCDVPL---DQLPR------SESLKDVLERLLPY
120 130 140 150 160
180 190 200 210 220 230
pF1KE0 GKNHSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPN
.. .. . . : ..:. .:: :.:. .. .: .....:
NP_954 WNE---RIAPEV-LRG--KTILISAHGNSSRALLKHL---------EGISDEDIINITLP
170 180 190 200 210
240 250 260 270
pF1KE0 TGMSLFIINFEEGREVKPTVQCICMNLQDHLNGLTETR
::. ... :. : : :
NP_954 TGVPILLELDENLRAVGPHQFLGDQEAIQAAIKKVEDQGKVKQAKK
220 230 240 250
>>NP_000281 (OMIM: 261670,612931) phosphoglycerate mutas (253 aa)
initn: 118 init1: 68 opt: 140 Z-score: 179.9 bits: 40.9 E(85289): 0.0028
Smith-Waterman score: 160; 25.3% identity (54.1% similar) in 257 aa overlap (1-251:1-227)
10 20 30 40 50
pF1KE0 MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQA--AAAGIFLNNVKFTHAFSSD
:: :..:::::. .:.:. . : : ::: : ..: .: .: ...: ..:
NP_000 MATHRLVMVRHGESTWNQENRFCGW-FDAELSEKGTEEAKRGAKAIKDAKMEFDICYTSV
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFT
: :. .:. .::. . . : :: ::.:: . : :.. .. :: ..:. ..
NP_000 LKRAIRTLWAILDGTDQMW-LPVVRTWRLNERHYGGLTG--LNKAETAAKHGEEQVKIWR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 PPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNC--LETSLAEIFPLGKNH
...: . .: . . : :: . .. : .: :. ..:. .:.
NP_000 ----RSFD-IPPPPMDEKHPYYNSISKER-RYAGLKPGELPTCESLKDTIARALPFW---
120 130 140 150 160
180 190 200 210 220 230
pF1KE0 SSKVNSDSGIPGLAAS--VLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTG
.. .: . :. ::...:: .:.. .. .: . .: .. ::
NP_000 -----NEEIVPQIKAGKRVLIAAHGNSLRGIVKHL---------EGMSDQAIMELNLPTG
170 180 190 200 210
240 250 260 270
pF1KE0 MSLFIINFEEGREVKPTVQCICMNLQDHLNGLTETR
. : .: ..:.:::
NP_000 IP---IVYELNKELKPTKPMQFLGDEETVRKAMEAVAAQGKAK
220 230 240 250
270 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:09:39 2016 done: Thu Nov 3 21:09:40 2016
Total Scan time: 7.330 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]