Result of FASTA (omim) for
pFN21AB6463
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6463, 322 aa
1>>>pF1KB6463 322 - 322 aa - 322 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8707+/-0.000324; mu= 10.5518+/- 0.020
mean_var=149.4150+/-30.058, 0's: 0 Z-trim(120.8): 6 B-trim: 1309 in 2/54
Lambda= 0.104925
statistics sampled from 36541 (36558) to 36541 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.766), E-opt: 0.2 (0.429), width: 16
Scan time: 8.280
The best scores are: opt bits E(85289)
NP_057651 (OMIM: 611883) BRCA2 and CDKN1A-interact ( 322) 2108 330.2 3.5e-90
NP_510869 (OMIM: 611883) BRCA2 and CDKN1A-interact ( 292) 1883 296.1 5.8e-80
NP_510868 (OMIM: 611883) BRCA2 and CDKN1A-interact ( 314) 1695 267.7 2.3e-71
>>NP_057651 (OMIM: 611883) BRCA2 and CDKN1A-interacting (322 aa)
initn: 2108 init1: 2108 opt: 2108 Z-score: 1740.1 bits: 330.2 E(85289): 3.5e-90
Smith-Waterman score: 2108; 100.0% identity (100.0% similar) in 322 aa overlap (1-322:1-322)
10 20 30 40 50 60
pF1KB6 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 KKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGGSRGQVTALVSLKAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGGSRGQVTALVSLKAGL
250 260 270 280 290 300
310 320
pF1KB6 IQSRSTLSDFQGTFMTVGIALS
::::::::::::::::::::::
NP_057 IQSRSTLSDFQGTFMTVGIALS
310 320
>>NP_510869 (OMIM: 611883) BRCA2 and CDKN1A-interacting (292 aa)
initn: 2183 init1: 1883 opt: 1883 Z-score: 1556.5 bits: 296.1 E(85289): 5.8e-80
Smith-Waterman score: 1883; 99.7% identity (99.7% similar) in 286 aa overlap (1-286:1-286)
10 20 30 40 50 60
pF1KB6 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 KKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGGSRGQVTALVSLKAGL
:::::::::::::::::::::::::::::::::::::::::::: :
NP_510 KKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGWSVPPVLE
250 260 270 280 290
310 320
pF1KB6 IQSRSTLSDFQGTFMTVGIALS
>>NP_510868 (OMIM: 611883) BRCA2 and CDKN1A-interacting (314 aa)
initn: 1995 init1: 1695 opt: 1695 Z-score: 1402.3 bits: 267.7 E(85289): 2.3e-71
Smith-Waterman score: 1695; 99.6% identity (100.0% similar) in 259 aa overlap (1-259:1-259)
10 20 30 40 50 60
pF1KB6 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 FEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 EDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 SERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 KKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGGSRGQVTALVSLKAGL
::::::::::::::::::.
NP_510 KKKAALMFANAEEEFFYEKAILKFNYSVQEESDTCLGGKWSFDDVPMTPLRTVMLIPGDK
250 260 270 280 290 300
322 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 23:04:42 2016 done: Fri Nov 4 23:04:44 2016
Total Scan time: 8.280 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]