Result of FASTA (ccds) for
pFN21AB3853
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3853, 212 aa
1>>>pF1KB3853 212 - 212 aa - 212 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1838+/-0.000772; mu= 13.9024+/- 0.046
mean_var=59.3033+/-12.279, 0's: 0 Z-trim(106.8): 28 B-trim: 0 in 0/49
Lambda= 0.166546
statistics sampled from 9203 (9223) to 9203 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.283), width: 16
Scan time: 2.030
The best scores are: opt bits E(32554)
CCDS82244.1 AQP4 gene_id:361|Hs108|chr18 ( 296) 878 219.1 2.2e-57
CCDS11889.1 AQP4 gene_id:361|Hs108|chr18 ( 323) 878 219.1 2.4e-57
CCDS58617.1 AQP4 gene_id:361|Hs108|chr18 ( 301) 709 178.5 3.8e-45
CCDS5431.1 AQP1 gene_id:358|Hs108|chr7 ( 269) 322 85.5 3.4e-17
CCDS8792.1 AQP2 gene_id:359|Hs108|chr12 ( 271) 321 85.3 4e-17
CCDS8793.1 AQP5 gene_id:362|Hs108|chr12 ( 265) 314 83.6 1.3e-16
CCDS8919.1 MIP gene_id:4284|Hs108|chr12 ( 263) 310 82.6 2.4e-16
>>CCDS82244.1 AQP4 gene_id:361|Hs108|chr18 (296 aa)
initn: 876 init1: 876 opt: 878 Z-score: 1143.6 bits: 219.1 E(32554): 2.2e-57
Smith-Waterman score: 911; 65.6% identity (65.6% similar) in 244 aa overlap (1-160:1-244)
10 20 30 40 50 60
pF1KB3 MSDRPTARRWGKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MSDRPTARRWGKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 GTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 GTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIA
70 80 90 100 110 120
pF1KB3 AQCLG-------------------------------------------------------
:::::
CCDS82 AQCLGAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDS
130 140 150 160 170 180
130 140 150
pF1KB3 -----------------------------PIIGAVLAGGLYEYVFCPDVEFKRRFKEAFS
:::::::::::::::::::::::::::::::
CCDS82 KRTDVTGSIALAIGFSVAIGHLFAIYWVGPIIGAVLAGGLYEYVFCPDVEFKRRFKEAFS
190 200 210 220 230 240
160 170 180 190 200 210
pF1KB3 KAAQQTKGSYMEVEDNRSQVETDDLILKPGVVHVIDVDRGEEKKGKDQSGEVLSSV
::::
CCDS82 KAAQQTKGSYMEVEDNRSQVETDDLILKPGVVHVIDVDRGEEKKGKDQSGEVLSSV
250 260 270 280 290
>--
initn: 331 init1: 331 opt: 331 Z-score: 433.3 bits: 87.7 E(32554): 8.2e-18
Smith-Waterman score: 331; 100.0% identity (100.0% similar) in 52 aa overlap (161-212:245-296)
140 150 160 170 180 190
pF1KB3 VLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDLILKPGVVHV
::::::::::::::::::::::::::::::
CCDS82 VLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDLILKPGVVHV
220 230 240 250 260 270
200 210
pF1KB3 IDVDRGEEKKGKDQSGEVLSSV
::::::::::::::::::::::
CCDS82 IDVDRGEEKKGKDQSGEVLSSV
280 290
>>CCDS11889.1 AQP4 gene_id:361|Hs108|chr18 (323 aa)
initn: 876 init1: 876 opt: 878 Z-score: 1143.0 bits: 219.1 E(32554): 2.4e-57
Smith-Waterman score: 878; 91.7% identity (93.1% similar) in 145 aa overlap (1-145:1-141)
10 20 30 40 50 60
pF1KB3 MSDRPTARRWGKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MSDRPTARRWGKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 GTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 GTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 AQCLGPIIGAVLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDD
::::: :::: :. : :.:
CCDS11 AQCLGAIIGA----GILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFA
130 140 150 160 170
>--
initn: 594 init1: 575 opt: 588 Z-score: 766.4 bits: 149.5 E(32554): 2.3e-36
Smith-Waterman score: 588; 69.5% identity (83.0% similar) in 141 aa overlap (73-212:189-323)
50 60 70 80 90 100
pF1KB3 LAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFG-HISGGHINPAVT
:.: .:.:.: . . :. . .:. .::: .
CCDS11 GLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVA-IGHLFAINYTGASMNPARS
160 170 180 190 200 210
110 120 130 140 150 160
pF1KB3 VAMVCTRKISIAKSVFYIAAQCLGPIIGAVLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQ
. . . .... :::::::::::::::::::::::::::::::::::::
CCDS11 FGPAVIMGNWENHWIYWV-----GPIIGAVLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQ
220 230 240 250 260 270
170 180 190 200 210
pF1KB3 TKGSYMEVEDNRSQVETDDLILKPGVVHVIDVDRGEEKKGKDQSGEVLSSV
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TKGSYMEVEDNRSQVETDDLILKPGVVHVIDVDRGEEKKGKDQSGEVLSSV
280 290 300 310 320
>>CCDS58617.1 AQP4 gene_id:361|Hs108|chr18 (301 aa)
initn: 707 init1: 707 opt: 709 Z-score: 924.0 bits: 178.5 E(32554): 3.8e-45
Smith-Waterman score: 709; 91.9% identity (92.7% similar) in 123 aa overlap (23-145:1-119)
10 20 30 40 50 60
pF1KB3 MSDRPTARRWGKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWG
::::::::::::::::::::::::::::::::::::::
CCDS58 MVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWG
10 20 30
70 80 90 100 110 120
pF1KB3 GTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 GTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB3 AQCLGPIIGAVLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDD
::::: :::: : :: : :.:
CCDS58 AQCLGAIIGA---GILY-LVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFA
100 110 120 130 140 150
>--
initn: 594 init1: 575 opt: 588 Z-score: 766.9 bits: 149.4 E(32554): 2.1e-36
Smith-Waterman score: 588; 69.5% identity (83.0% similar) in 141 aa overlap (73-212:167-301)
50 60 70 80 90 100
pF1KB3 LAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFG-HISGGHINPAVT
:.: .:.:.: . . :. . .:. .::: .
CCDS58 GLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVA-IGHLFAINYTGASMNPARS
140 150 160 170 180 190
110 120 130 140 150 160
pF1KB3 VAMVCTRKISIAKSVFYIAAQCLGPIIGAVLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQ
. . . .... :::::::::::::::::::::::::::::::::::::
CCDS58 FGPAVIMGNWENHWIYWV-----GPIIGAVLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQ
200 210 220 230 240 250
170 180 190 200 210
pF1KB3 TKGSYMEVEDNRSQVETDDLILKPGVVHVIDVDRGEEKKGKDQSGEVLSSV
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 TKGSYMEVEDNRSQVETDDLILKPGVVHVIDVDRGEEKKGKDQSGEVLSSV
260 270 280 290 300
>>CCDS5431.1 AQP1 gene_id:358|Hs108|chr7 (269 aa)
initn: 324 init1: 234 opt: 322 Z-score: 422.3 bits: 85.5 E(32554): 3.4e-17
Smith-Waterman score: 322; 48.6% identity (80.0% similar) in 105 aa overlap (34-134:10-114)
10 20 30 40 50 60
pF1KB3 RPTARRWGKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWG---
::.::.::::: .::..:.::....
CCDS54 MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPV
10 20 30
70 80 90 100 110 120
pF1KB3 GTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIA
:... : : .:: :::::::..: :::::.:.:::::.... . .::: ....::
CCDS54 GNNQTAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYII
40 50 60 70 80 90
130 140 150 160 170
pF1KB3 AQCLGPIIG-AVLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETD
:::.: :.. :.:.:
CCDS54 AQCVGAIVATAILSGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDR
100 110 120 130 140 150
>>CCDS8792.1 AQP2 gene_id:359|Hs108|chr12 (271 aa)
initn: 320 init1: 222 opt: 321 Z-score: 420.9 bits: 85.3 E(32554): 4e-17
Smith-Waterman score: 321; 52.0% identity (80.0% similar) in 100 aa overlap (33-132:8-103)
10 20 30 40 50 60
pF1KB3 DRPTARRWGKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWGGT
:: .:: ::::: :.::...:::..::
CCDS87 MWELRSIAFSRAVFAEFLATLLFVFFGLGSALNW---
10 20 30
70 80 90 100 110 120
pF1KB3 EKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQ
. :: ... :.. :::.:.:.:: .:::::.::::::::: . ..:. ...::.:::
CCDS87 PQALP-SVLQIAMAFGLGIGTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQ
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB3 CLGPIIGAVLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDLI
:: . ::.:
CCDS87 LLGAVAGAALLHEITPADIRGDLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTDERR
100 110 120 130 140 150
>>CCDS8793.1 AQP5 gene_id:362|Hs108|chr12 (265 aa)
initn: 396 init1: 213 opt: 314 Z-score: 412.0 bits: 83.6 E(32554): 1.3e-16
Smith-Waterman score: 314; 49.5% identity (77.1% similar) in 109 aa overlap (27-134:3-107)
10 20 30 40 50 60
pF1KB3 MSDRPTARRWGKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWG
: : . :: ::: ::::: ::::...:::...:
CCDS87 MKKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWP
10 20 30
70 80 90 100 110 120
pF1KB3 GTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIA
.. ::. .. :.: :::.:.:..: .: .::::::::.:.:.. .::. .. ::.:
CCDS87 SA---LPT-ILQIALAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVA
40 50 60 70 80 90
130 140 150 160 170
pF1KB3 AQCLGPIIGA-VLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETD
:: .: : :: .: :
CCDS87 AQLVGAIAGAGILYGVAPLNARGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTDS
100 110 120 130 140 150
>>CCDS8919.1 MIP gene_id:4284|Hs108|chr12 (263 aa)
initn: 289 init1: 194 opt: 310 Z-score: 406.8 bits: 82.6 E(32554): 2.4e-16
Smith-Waterman score: 310; 42.2% identity (76.5% similar) in 102 aa overlap (31-132:6-103)
10 20 30 40 50 60
pF1KB3 MSDRPTARRWGKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWG
. .::.:. :::.: :..:...:::.. :.
CCDS89 MWELRSASFWRAIFAEFFATLFYVFFGLGSSLRWA
10 20 30
70 80 90 100 110 120
pF1KB3 GTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIA
: :. .. ... :::..::.:: :::::.:.::::: :.. ..:. .. :.:
CCDS89 ----PGPLHVLQVAMAFGLALATLVQSVGHISGAHVNPAVTFAFLVGSQMSLLRAFCYMA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB3 AQCLGPIIGAVLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDD
:: :: . ::..
CCDS89 AQLLGAVAGAAVLYSVTPPAVRGNLALNTLHPAVSVGQATTVEIFLTLQFVLCIFATYDE
100 110 120 130 140 150
212 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 09:05:47 2016 done: Sat Nov 5 09:05:48 2016
Total Scan time: 2.030 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]