Result of FASTA (omim) for
pFN21AE0553
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0553, 357 aa
1>>>pF1KE0553 357 - 357 aa - 357 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9009+/-0.000401; mu= 18.2713+/- 0.025
mean_var=61.5029+/-12.491, 0's: 0 Z-trim(111.6): 44 B-trim: 138 in 2/49
Lambda= 0.163541
statistics sampled from 20150 (20194) to 20150 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.609), E-opt: 0.2 (0.237), width: 16
Scan time: 6.720
The best scores are: opt bits E(85289)
NP_001257340 (OMIM: 607110) DNA dC->dU-editing enz ( 357) 2588 619.4 3.9e-177
NP_004891 (OMIM: 607110) DNA dC->dU-editing enzyme ( 382) 1753 422.4 8.2e-118
NP_660341 (OMIM: 608993) DNA dC->dU-editing enzyme ( 373) 1200 291.9 1.5e-78
XP_016884131 (OMIM: 608993) PREDICTED: DNA dC->dU- ( 227) 1127 274.5 1.6e-73
XP_016884392 (OMIM: 607113) PREDICTED: DNA dC->dU- ( 524) 902 221.7 2.9e-57
NP_689639 (OMIM: 609900) DNA dC->dU-editing enzyme ( 386) 822 202.7 1.1e-51
NP_001257335 (OMIM: 607109) DNA dC->dU-editing enz ( 181) 804 198.3 1.1e-50
NP_663745 (OMIM: 607109) DNA dC->dU-editing enzyme ( 199) 804 198.3 1.2e-50
NP_055323 (OMIM: 607750) DNA dC->dU-editing enzyme ( 190) 710 176.1 5.6e-44
XP_011528296 (OMIM: 608993) PREDICTED: DNA dC->dU- ( 442) 703 174.7 3.5e-43
XP_016884085 (OMIM: 609900) PREDICTED: DNA dC->dU- ( 455) 677 168.6 2.5e-41
XP_016884393 (OMIM: 607113) PREDICTED: DNA dC->dU- ( 457) 651 162.4 1.8e-39
XP_005261394 (OMIM: 609900) PREDICTED: DNA dC->dU- ( 202) 530 133.6 3.6e-31
XP_006724353 (OMIM: 607113) PREDICTED: DNA dC->dU- ( 317) 524 132.4 1.4e-30
NP_068594 (OMIM: 607113) DNA dC->dU-editing enzyme ( 384) 524 132.4 1.6e-30
NP_065712 (OMIM: 605257,605258) single-stranded DN ( 198) 355 92.4 9.5e-19
XP_011528293 (OMIM: 610976) PREDICTED: DNA dC->dU- ( 203) 337 88.1 1.8e-17
XP_011528292 (OMIM: 610976) PREDICTED: DNA dC->dU- ( 203) 337 88.1 1.8e-17
NP_001159474 (OMIM: 610976) DNA dC->dU-editing enz ( 182) 336 87.8 2e-17
NP_861438 (OMIM: 610976) DNA dC->dU-editing enzyme ( 183) 336 87.8 2e-17
NP_001159475 (OMIM: 610976) DNA dC->dU-editing enz ( 200) 336 87.9 2.1e-17
XP_011528294 (OMIM: 610976) PREDICTED: DNA dC->dU- ( 200) 336 87.9 2.1e-17
NP_006780 (OMIM: 604797) C->U-editing enzyme APOBE ( 224) 335 87.7 2.8e-17
NP_001317272 (OMIM: 605257,605258) single-stranded ( 188) 313 82.4 8.8e-16
NP_001291495 (OMIM: 600130) C->U-editing enzyme AP ( 236) 310 81.8 1.7e-15
NP_001635 (OMIM: 600130) C->U-editing enzyme APOBE ( 236) 310 81.8 1.7e-15
XP_011519075 (OMIM: 605257,605258) PREDICTED: sing ( 145) 307 80.9 1.9e-15
NP_005880 (OMIM: 600130) C->U-editing enzyme APOBE ( 191) 295 78.2 1.7e-14
NP_001159476 (OMIM: 610976) DNA dC->dU-editing enz ( 154) 249 67.3 2.6e-11
NP_001006667 (OMIM: 608993) DNA dC->dU-editing enz ( 101) 233 63.4 2.6e-10
XP_016884132 (OMIM: 608993) PREDICTED: DNA dC->dU- ( 101) 233 63.4 2.6e-10
>>NP_001257340 (OMIM: 607110) DNA dC->dU-editing enzyme (357 aa)
initn: 2588 init1: 2588 opt: 2588 Z-score: 3301.2 bits: 619.4 E(85289): 3.9e-177
Smith-Waterman score: 2588; 99.7% identity (100.0% similar) in 357 aa overlap (1-357:1-357)
10 20 30 40 50 60
pF1KE0 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FEPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTISA
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTISA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ARLYYYWERDYRRALCRLSQAGARVKIMDYEEFAYCWENFVYNEGQQFMPWYKFDENYAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARLYYYWERDYRRALCRLSQAGARVKIMDYEEFAYCWENFVYNEGQQFMPWYKFDENYAF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHMGFLCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHMGFLCN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ELDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQM
250 260 270 280 290 300
310 320 330 340 350
pF1KE0 LRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQNQGN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQNQGN
310 320 330 340 350
>>NP_004891 (OMIM: 607110) DNA dC->dU-editing enzyme APO (382 aa)
initn: 1753 init1: 1753 opt: 1753 Z-score: 2236.1 bits: 422.4 E(85289): 8.2e-118
Smith-Waterman score: 2528; 93.2% identity (93.5% similar) in 382 aa overlap (1-357:1-382)
10 20 30 40 50 60
pF1KE0 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FEPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTISA
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FKPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTISA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ARLYYYWERDYRRALCRLSQAGARVKIMDYEEFAYCWENFVYNEGQQFMPWYKFDENYAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ARLYYYWERDYRRALCRLSQAGARVKIMDYEEFAYCWENFVYNEGQQFMPWYKFDENYAF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHMGFLCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHMGFLCN
190 200 210 220 230 240
250 260 270
pF1KE0 E-------------------------LDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQEN
: ::::::::::::::::::::::::::::::::::
NP_004 EAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQEN
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE0 THVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 THVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWD
310 320 330 340 350 360
340 350
pF1KE0 GLEEHSQALSGRLRAILQNQGN
::::::::::::::::::::::
NP_004 GLEEHSQALSGRLRAILQNQGN
370 380
>>NP_660341 (OMIM: 608993) DNA dC->dU-editing enzyme APO (373 aa)
initn: 1454 init1: 952 opt: 1200 Z-score: 1531.1 bits: 291.9 E(85289): 1.5e-78
Smith-Waterman score: 1504; 59.8% identity (76.6% similar) in 376 aa overlap (1-353:1-373)
10 20 30 40 50 60
pF1KE0 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY
:.:..:: .:::::::: :: :.::: :. .::::::: : : : :. .::::::
NP_660 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTK-GPSRPRLDAKIFRGQVY
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 FEPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTISA
.:..:::::::::::::::::::::::::::::::::::::::::::.:::::::::::
NP_660 SQPEHHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 ARLYYYWERDYRRALCRLSQAGARVKIMDYEEFAYCWENFVYNEGQQFMPWYKFDENYAF
::::::::::::::::::::::::::::: ::::::::::::.::: ::::::::.::::
NP_660 ARLYYYWERDYRRALCRLSQAGARVKIMDDEEFAYCWENFVYSEGQPFMPWYKFDDNYAF
120 130 140 150 160 170
190 200 210 220 230
pF1KE0 LHRTLKEILRYLMD---PDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGT---W---VLM
:::::::::: :. : : :.:.: . : ...::. .: . . . : :.
NP_660 LHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPVSWKRGVFR
180 190 200 210 220 230
240 250 260 270
pF1KE0 DQ-----H-------MGFLCNE-LDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
.: : ....:.. :.: :.:::. ::::: ::::: :: ....:
NP_660 NQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPE--CAGEVAEFLARHSNV
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE0 RLRIFAARIYDY-DPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWDGL
: ::.::.: . : :.:.:. : . ::.: :: : .:.:::..::: . ::.:: ::
NP_660 NLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYNDDEPFKPWKGL
300 310 320 330 340 350
340 350
pF1KE0 EEHSQALSGRLRAILQNQGN
. . :...:. ::.
NP_660 KYNFLFLDSKLQEILE
360 370
>>XP_016884131 (OMIM: 608993) PREDICTED: DNA dC->dU-edit (227 aa)
initn: 1125 init1: 952 opt: 1127 Z-score: 1441.1 bits: 274.5 E(85289): 1.6e-73
Smith-Waterman score: 1127; 82.6% identity (90.5% similar) in 190 aa overlap (1-190:1-189)
10 20 30 40 50 60
pF1KE0 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY
:.:..:: .:::::::: :: :.::: :. .::::::: : : : :. .::::::
XP_016 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTK-GPSRPRLDAKIFRGQVY
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 FEPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTISA
.:..:::::::::::::::::::::::::::::::::::::::::::.:::::::::::
XP_016 SQPEHHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 ARLYYYWERDYRRALCRLSQAGARVKIMDYEEFAYCWENFVYNEGQQFMPWYKFDENYAF
::::::::::::::::::::::::::::: ::::::::::::.::: ::::::::.::::
XP_016 ARLYYYWERDYRRALCRLSQAGARVKIMDDEEFAYCWENFVYSEGQPFMPWYKFDDNYAF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 LHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHMGFLCN
::::::::::
XP_016 LHRTLKEILRATSIHLRGRPPHSLGSPTWLLPSPWHNRICHKTGRKWA
180 190 200 210 220
>>XP_016884392 (OMIM: 607113) PREDICTED: DNA dC->dU-edit (524 aa)
initn: 1156 init1: 415 opt: 902 Z-score: 1149.0 bits: 221.7 E(85289): 2.9e-57
Smith-Waterman score: 1339; 53.8% identity (71.0% similar) in 383 aa overlap (1-353:1-380)
10 20 30 40 50 60
pF1KE0 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY
:.:..:: .:::::::: :: :.::: :. .::::::: : : : :. .::::::
XP_016 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTK-GPSRPPLDAKIFRGQVY
10 20 30 40 50
70 80 90 100 110
pF1KE0 FEPQYHAEMCFLSWFCG-NQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTIS
: .:: :: :. :: .: . ...::..::.:: :. .: ::.: :.:::::
XP_016 SELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 AARLYYYWERDYRRALCRLSQA--GAR--VKIMDYEEFAYCWENFVYNEGQQFMPWYKFD
.:::::.:. ::..:: : : : : .:::.:.:: .:: .:::.. . : :: ..
XP_016 VARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 ENYAFLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHM
. : .:: : ::::. ::: ::::::::.: : :..:::::::::. : ::::..:.
XP_016 KYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRR
180 190 200 210 220 230
240 250 260 270
pF1KE0 GFLCNE-------------------------LDPAQIYRVTWFISWSPCFSWGCAGEVRA
:::::. :: : :::: : ::::::: :: :.
XP_016 GFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFS--CAQEMAK
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE0 FLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCP
:...: :: : ::.::::: . .:.:. : .:::..:::::.::..:::::: .::::
XP_016 FISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCP
300 310 320 330 340 350
340 350
pF1KE0 FQPWDGLEEHSQALSGRLRAILQNQGN
:::::::.:::: ::::::::::
XP_016 FQPWDGLDEHSQDLSGRLRAILQVRASSLCPVPHRPPPPPLSPAPCLPLCSEPPLGSLLP
360 370 380 390 400 410
>>NP_689639 (OMIM: 609900) DNA dC->dU-editing enzyme APO (386 aa)
initn: 1076 init1: 749 opt: 822 Z-score: 1048.9 bits: 202.7 E(85289): 1.1e-51
Smith-Waterman score: 1482; 58.8% identity (74.0% similar) in 388 aa overlap (1-353:1-386)
10 20 30 40 50
pF1KE0 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRG---
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVL
10 20 30 40 50 60
60 70 80 90 100
pF1KE0 ---------QVYFEPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFL
.:::. . :::::::::::::.::: . :::::::::.:: ::.:...::
NP_689 PKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 SEHPNVTLTISAARLYYYWERDYRRALCRLSQAGARVKIMDYEEFAYCWENFVYNEGQQF
.::::::::::::::::: .::.: .: :: .:::::::::::.::::::::: :::: :
NP_689 AEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPF
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 MPWYKFDENYAFLHRTLKEILRYLMD---PDTFTFNFNNDPLVLRRRQTYLCYEVERLDN
:::::::.::: :::::::::: :. : : :.:.: . : ...::. .: .
NP_689 MPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKH
190 200 210 220 230 240
230 240 250 260
pF1KE0 GTWVLM-----------DQH-------MGFLCNE-LDPAQIYRVTWFISWSPCFSWGCAG
. :. . : ....:.. :.: :.:::. ::::: :::
NP_689 HSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPE--CAG
250 260 270 280 290
270 280 290 300 310 320
pF1KE0 EVRAFLQENTHVRLRIFAARI-YDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVY
:: :: ....: : ::.::. : .: :.:.: : . ::.:.:: : .: :: .:::
NP_689 EVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVY
300 310 320 330 340 350
330 340 350
pF1KE0 RQGCPFQPWDGLEEHSQALSGRLRAILQNQGN
. ::.:: ::. . . :. ::: :::
NP_689 SDDEPFKPWKGLQTNFRLLKRRLREILQ
360 370 380
>>NP_001257335 (OMIM: 607109) DNA dC->dU-editing enzyme (181 aa)
initn: 804 init1: 804 opt: 804 Z-score: 1030.6 bits: 198.3 E(85289): 1.1e-50
Smith-Waterman score: 902; 78.5% identity (82.6% similar) in 172 aa overlap (211-357:10-181)
190 200 210 220 230 240
pF1KE0 LHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHMGFLCN
:..:::::::::::::: : :::: ::: :
NP_001 MEASPASGPRHKTYLCYEVERLDNGTSVKMDQHRGFLHN
10 20 30
250 260 270
pF1KE0 E-------------------------LDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQEN
. ::::::::::::::::::::::::::::::::::
NP_001 QAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQEN
40 50 60 70 80 90
280 290 300 310 320 330
pF1KE0 THVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWD
:::::::::::::::::::::::::::::::::::::::::..:::::: .:::::::::
NP_001 THVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWD
100 110 120 130 140 150
340 350
pF1KE0 GLEEHSQALSGRLRAILQNQGN
::.:::::::::::::::::::
NP_001 GLDEHSQALSGRLRAILQNQGN
160 170 180
>>NP_663745 (OMIM: 607109) DNA dC->dU-editing enzyme APO (199 aa)
initn: 866 init1: 804 opt: 804 Z-score: 1030.1 bits: 198.3 E(85289): 1.2e-50
Smith-Waterman score: 960; 75.6% identity (80.3% similar) in 193 aa overlap (190-357:10-199)
160 170 180 190 200 210
pF1KE0 FVYNEGQQFMPWYKFDENYAFLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYE
:.:::: :: :::: . :..::::::
NP_663 MEASPASGPRHLMDPHIFTSNFNNG---IGRHKTYLCYE
10 20 30
220 230 240 250
pF1KE0 VERLDNGTWVLMDQHMGFLCNE-------------------------LDPAQIYRVTWFI
:::::::: : :::: ::: :. :::::::::::::
NP_663 VERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFI
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE0 SWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 SWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYD
100 110 120 130 140 150
320 330 340 350
pF1KE0 EFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQNQGN
::..:::::: .:::::::::::.:::::::::::::::::::
NP_663 EFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
160 170 180 190
>>NP_055323 (OMIM: 607750) DNA dC->dU-editing enzyme APO (190 aa)
initn: 676 init1: 676 opt: 710 Z-score: 910.5 bits: 176.1 E(85289): 5.6e-44
Smith-Waterman score: 710; 53.9% identity (74.3% similar) in 191 aa overlap (1-190:1-190)
10 20 30 40 50
pF1KE0 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVK-IKRGRSNLLWDTGVFRGQV
:::::::::. :: ::: .:.: :. ::::. :. ::: :: . : :::::.::
NP_055 MNPQIRNPMKAMYPGTFYFQFKNLWEANDRNETWLCFTVEGIKR-RSVVSWKTGVFRNQV
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 YFEPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTIS
: . ::: ::::::: . : .:.::..::.:::::....::::..: ::.:::
NP_055 DSETHCHAERCFLSWFCDDILSPNTKYQVTWYTSWSPCPDCAGEVAEFLARHSNVNLTIF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 AARLYYYWERDYRRALCRLSQAGARVKIMDYEEFAYCWENFVYNEGQQFMPWYKFDENYA
.:::::. :...: ::: :. :.:::::.: :::::::::... : :: . :.
NP_055 TARLYYFQYPCYQEGLRSLSQEGVAVEIMDYEDFKYCWENFVYNDNEPFKPWKGLKTNFR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 FLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHMGFLC
.:.: :.: :.
NP_055 LLKRRLRESLQ
180 190
>>XP_011528296 (OMIM: 608993) PREDICTED: DNA dC->dU-edit (442 aa)
initn: 1410 init1: 703 opt: 703 Z-score: 896.3 bits: 174.7 E(85289): 3.5e-43
Smith-Waterman score: 967; 60.3% identity (66.1% similar) in 257 aa overlap (1-188:1-256)
10 20 30 40 50 60
pF1KE0 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY
:.:..:: .:::::::: :: :.::: :. .::::::: : : : :. .::::::
XP_011 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTK-GPSRPRLDAKIFRGQVY
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 FEPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTISA
.:..:::::::::::::::::::::::::::::::::::::::::::.:::::::::::
XP_011 SQPEHHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISA
60 70 80 90 100 110
130 140 150
pF1KE0 ARLYYYWERDYRRALCRLSQAGARVKIMDYE-----------------------------
::::::::::::::::::::::::::::: :
XP_011 ARLYYYWERDYRRALCRLSQAGARVKIMDDEGERWRGQGSVSGRNSMKDGWICNAMAGGV
120 130 140 150 160 170
160 170
pF1KE0 ----------------------------------------EFAYCWENFVYNEGQQFMPW
:::::::::::.::: ::::
XP_011 PGQPAGAGPALTATDSQETRPGSAGPGSGQSLTASCLFVSEFAYCWENFVYSEGQPFMPW
180 190 200 210 220 230
180 190 200 210 220 230
pF1KE0 YKFDENYAFLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLM
::::.::::::::::::
XP_011 YKFDDNYAFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSP
240 250 260 270 280 290
>--
initn: 1410 init1: 703 opt: 703 Z-score: 896.3 bits: 174.7 E(85289): 3.5e-43
Smith-Waterman score: 703; 50.3% identity (73.5% similar) in 185 aa overlap (5-189:257-441)
10 20 30
pF1KE0 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTW
.::::: :: :: .:.: :::. .:
XP_011 NFVYSEGQPFMPWYKFDDNYAFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESW
230 240 250 260 270 280
40 50 60 70 80 90
pF1KE0 LCYEVKIKRGRSNLLWDTGVFRGQVYFEPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSW
::. ... . .: . : ::::.:: : . ::: ::::::: . : ...::..::
XP_011 LCFTMEVVKHHSPVSWKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSW
290 300 310 320 330 340
100 110 120 130 140 150
pF1KE0 TPCPDCVAKLAEFLSEHPNVTLTISAARLYYYWERDYRRALCRLSQAGARVKIMDYEEFA
.:::.:....::::..: ::.::: .:::::.:. ::...: ::: :: :.:: :..:
XP_011 SPCPECAGEVAEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFK
350 360 370 380 390 400
160 170 180 190 200 210
pF1KE0 YCWENFVYNEGQQFMPWYKFDENYAFLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQT
:::::::::. . : :: . :. :: :.:::
XP_011 YCWENFVYNDDEPFKPWKGLKYNFLFLDSKLQEILE
410 420 430 440
220 230 240 250 260 270
pF1KE0 YLCYEVERLDNGTWVLMDQHMGFLCNELDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQE
357 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 23:41:10 2016 done: Wed Nov 2 23:41:11 2016
Total Scan time: 6.720 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]