Result of FASTA (omim) for
pFN21AE0352
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0352, 530 aa
1>>>pF1KE0352 530 - 530 aa - 530 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2575+/-0.000432; mu= 13.5186+/- 0.027
mean_var=77.5222+/-15.689, 0's: 0 Z-trim(111.2): 41 B-trim: 616 in 1/50
Lambda= 0.145667
statistics sampled from 19676 (19714) to 19676 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.599), E-opt: 0.2 (0.231), width: 16
Scan time: 8.120
The best scores are: opt bits E(85289)
NP_006612 (OMIM: 607826) adenosylhomocysteinase 2 ( 530) 3545 754.9 1.3e-217
XP_011538837 (OMIM: 607826) PREDICTED: adenosylhom ( 505) 3265 696.1 6.5e-200
NP_001229603 (OMIM: 607826) adenosylhomocysteinase ( 483) 3238 690.4 3.2e-198
NP_001229605 (OMIM: 607826) adenosylhomocysteinase ( 483) 3238 690.4 3.2e-198
NP_001229602 (OMIM: 607826) adenosylhomocysteinase ( 483) 3238 690.4 3.2e-198
NP_001229604 (OMIM: 607826) adenosylhomocysteinase ( 483) 3238 690.4 3.2e-198
NP_056143 (OMIM: 616520) adenosylhomocysteinase 3 ( 611) 3129 667.5 3.1e-191
NP_001124192 (OMIM: 616520) adenosylhomocysteinase ( 610) 3123 666.3 7.4e-191
NP_001124194 (OMIM: 616520) adenosylhomocysteinase ( 508) 3110 663.5 4.2e-190
NP_001124195 (OMIM: 616520) adenosylhomocysteinase ( 508) 3103 662.1 1.2e-189
XP_011514289 (OMIM: 616520) PREDICTED: adenosylhom ( 509) 3102 661.8 1.3e-189
XP_011514290 (OMIM: 616520) PREDICTED: adenosylhom ( 509) 3102 661.8 1.3e-189
XP_005250294 (OMIM: 616520) PREDICTED: adenosylhom ( 509) 3102 661.8 1.3e-189
XP_016867393 (OMIM: 616520) PREDICTED: adenosylhom ( 404) 2619 560.3 3.9e-159
XP_016867396 (OMIM: 616520) PREDICTED: adenosylhom ( 404) 2619 560.3 3.9e-159
XP_016867394 (OMIM: 616520) PREDICTED: adenosylhom ( 404) 2619 560.3 3.9e-159
XP_016867395 (OMIM: 616520) PREDICTED: adenosylhom ( 404) 2619 560.3 3.9e-159
NP_001309015 (OMIM: 180960,613752) adenosylhomocys ( 434) 1494 323.9 6.2e-88
XP_011526958 (OMIM: 180960,613752) PREDICTED: aden ( 434) 1494 323.9 6.2e-88
XP_011526960 (OMIM: 180960,613752) PREDICTED: aden ( 434) 1494 323.9 6.2e-88
XP_011526959 (OMIM: 180960,613752) PREDICTED: aden ( 434) 1494 323.9 6.2e-88
XP_016883198 (OMIM: 180960,613752) PREDICTED: aden ( 432) 1489 322.8 1.3e-87
XP_016883197 (OMIM: 180960,613752) PREDICTED: aden ( 432) 1489 322.8 1.3e-87
NP_000678 (OMIM: 180960,613752) adenosylhomocystei ( 432) 1489 322.8 1.3e-87
XP_011526961 (OMIM: 180960,613752) PREDICTED: aden ( 404) 1437 311.9 2.3e-84
NP_001155238 (OMIM: 180960,613752) adenosylhomocys ( 404) 1437 311.9 2.3e-84
XP_005260374 (OMIM: 180960,613752) PREDICTED: aden ( 404) 1437 311.9 2.3e-84
NP_001309014 (OMIM: 180960,613752) adenosylhomocys ( 404) 1437 311.9 2.3e-84
NP_001309013 (OMIM: 180960,613752) adenosylhomocys ( 404) 1437 311.9 2.3e-84
XP_016883199 (OMIM: 180960,613752) PREDICTED: aden ( 306) 1070 234.7 3e-61
>>NP_006612 (OMIM: 607826) adenosylhomocysteinase 2 isof (530 aa)
initn: 3545 init1: 3545 opt: 3545 Z-score: 4027.8 bits: 754.9 E(85289): 1.3e-217
Smith-Waterman score: 3545; 100.0% identity (100.0% similar) in 530 aa overlap (1-530:1-530)
10 20 30 40 50 60
pF1KE0 MSMPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MSMPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 RSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 EIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 STQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 STQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 YPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 NEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 SQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
430 440 450 460 470 480
490 500 510 520 530
pF1KE0 VYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
490 500 510 520 530
>>XP_011538837 (OMIM: 607826) PREDICTED: adenosylhomocys (505 aa)
initn: 3264 init1: 3264 opt: 3265 Z-score: 3710.1 bits: 696.1 E(85289): 6.5e-200
Smith-Waterman score: 3265; 98.2% identity (98.6% similar) in 501 aa overlap (1-497:1-501)
10 20 30 40 50 60
pF1KE0 MSMPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSMPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 RSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 EIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 STQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 YPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 NEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 SQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
430 440 450 460 470 480
490 500 510 520 530
pF1KE0 VYLLPKKMDE----YVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
::::::::: : . .::
XP_011 VYLLPKKMDTNGPYYQGPVHLNHTL
490 500
>>NP_001229603 (OMIM: 607826) adenosylhomocysteinase 2 i (483 aa)
initn: 3238 init1: 3238 opt: 3238 Z-score: 3679.7 bits: 690.4 E(85289): 3.2e-198
Smith-Waterman score: 3238; 100.0% identity (100.0% similar) in 483 aa overlap (48-530:1-483)
20 30 40 50 60 70
pF1KE0 QAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGRRSLSRSISQSSTDSYSS
::::::::::::::::::::::::::::::
NP_001 MQEFTKFPTKTGRRSLSRSISQSSTDSYSS
10 20 30
80 90 100 110 120 130
pF1KE0 AASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRA
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE0 QGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAV
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE0 FAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVT
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE0 GVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVC
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE0 GYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNK
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE0 NVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLL
340 350 360 370 380 390
440 450 460 470 480 490
pF1KE0 AEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHL
400 410 420 430 440 450
500 510 520 530
pF1KE0 PSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
:::::::::::::::::::::::::::::::::
NP_001 PSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
460 470 480
>>NP_001229605 (OMIM: 607826) adenosylhomocysteinase 2 i (483 aa)
initn: 3238 init1: 3238 opt: 3238 Z-score: 3679.7 bits: 690.4 E(85289): 3.2e-198
Smith-Waterman score: 3238; 100.0% identity (100.0% similar) in 483 aa overlap (48-530:1-483)
20 30 40 50 60 70
pF1KE0 QAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGRRSLSRSISQSSTDSYSS
::::::::::::::::::::::::::::::
NP_001 MQEFTKFPTKTGRRSLSRSISQSSTDSYSS
10 20 30
80 90 100 110 120 130
pF1KE0 AASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRA
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE0 QGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAV
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE0 FAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVT
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE0 GVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVC
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE0 GYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNK
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE0 NVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLL
340 350 360 370 380 390
440 450 460 470 480 490
pF1KE0 AEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHL
400 410 420 430 440 450
500 510 520 530
pF1KE0 PSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
:::::::::::::::::::::::::::::::::
NP_001 PSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
460 470 480
>>NP_001229602 (OMIM: 607826) adenosylhomocysteinase 2 i (483 aa)
initn: 3238 init1: 3238 opt: 3238 Z-score: 3679.7 bits: 690.4 E(85289): 3.2e-198
Smith-Waterman score: 3238; 100.0% identity (100.0% similar) in 483 aa overlap (48-530:1-483)
20 30 40 50 60 70
pF1KE0 QAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGRRSLSRSISQSSTDSYSS
::::::::::::::::::::::::::::::
NP_001 MQEFTKFPTKTGRRSLSRSISQSSTDSYSS
10 20 30
80 90 100 110 120 130
pF1KE0 AASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRA
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE0 QGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAV
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE0 FAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVT
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE0 GVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVC
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE0 GYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNK
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE0 NVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLL
340 350 360 370 380 390
440 450 460 470 480 490
pF1KE0 AEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHL
400 410 420 430 440 450
500 510 520 530
pF1KE0 PSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
:::::::::::::::::::::::::::::::::
NP_001 PSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
460 470 480
>>NP_001229604 (OMIM: 607826) adenosylhomocysteinase 2 i (483 aa)
initn: 3238 init1: 3238 opt: 3238 Z-score: 3679.7 bits: 690.4 E(85289): 3.2e-198
Smith-Waterman score: 3238; 100.0% identity (100.0% similar) in 483 aa overlap (48-530:1-483)
20 30 40 50 60 70
pF1KE0 QAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGRRSLSRSISQSSTDSYSS
::::::::::::::::::::::::::::::
NP_001 MQEFTKFPTKTGRRSLSRSISQSSTDSYSS
10 20 30
80 90 100 110 120 130
pF1KE0 AASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRA
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE0 QGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAV
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE0 FAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVT
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE0 GVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVC
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE0 GYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNK
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE0 NVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLL
340 350 360 370 380 390
440 450 460 470 480 490
pF1KE0 AEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHL
400 410 420 430 440 450
500 510 520 530
pF1KE0 PSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
:::::::::::::::::::::::::::::::::
NP_001 PSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
460 470 480
>>NP_056143 (OMIM: 616520) adenosylhomocysteinase 3 isof (611 aa)
initn: 3114 init1: 3114 opt: 3129 Z-score: 3554.3 bits: 667.5 E(85289): 3.1e-191
Smith-Waterman score: 3129; 92.0% identity (97.4% similar) in 501 aa overlap (33-530:111-611)
10 20 30 40 50
pF1KE0 MPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAP---KKQIQFADDMQEFTKFPTKTG
:::.:: ::::::::. :::.: ::: :
NP_056 PQASAMKRSDPHHQHQRHRDGGEALVSPDGTVTEAPRTVKKQIQFADQKQEFNKRPTKIG
90 100 110 120 130 140
60 70 80 90 100 110
pF1KE0 RRSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRRE
:::::::::::::::::::::::::::::.:::.::: ::::::.:::::::::::::::
NP_056 RRSLSRSISQSSTDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRRE
150 160 170 180 190 200
120 130 140 150 160 170
pF1KE0 IEIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNI
::::::.: ::..:::::::::::::::::::::::::::::.::: ::::::::.::::
NP_056 IEIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNI
210 220 230 240 250 260
180 190 200 210 220 230
pF1KE0 YSTQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYK
::: :::::::::.: :::::::::::::::::::::..::: :::::::::::::.::
NP_056 YSTLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYK
270 280 290 300 310 320
240 250 260 270 280 290
pF1KE0 KYPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILD
::::.::::.::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KYPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILD
330 340 350 360 370 380
300 310 320 330 340 350
pF1KE0 GLKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVK
:::::::.:::::::::::::::::::::::::.:.:::.:::::::::::::::::.::
NP_056 GLKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVK
390 400 410 420 430 440
360 370 380 390 400 410
pF1KE0 LNEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERV
:::::::::.:::::::::::::::::::::::::::::::::::::.::::::::::::
NP_056 LNEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERV
450 460 470 480 490 500
420 430 440 450 460 470
pF1KE0 RSQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQ
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
NP_056 RSQVDHVIWPDGKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQ
510 520 530 540 550 560
480 490 500 510 520 530
pF1KE0 DVYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
:::::::::::::::::::.::::::::::.::::::::::::::::::::
NP_056 DVYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
570 580 590 600 610
>>NP_001124192 (OMIM: 616520) adenosylhomocysteinase 3 i (610 aa)
initn: 3103 init1: 3103 opt: 3123 Z-score: 3547.5 bits: 666.3 E(85289): 7.4e-191
Smith-Waterman score: 3123; 91.8% identity (97.6% similar) in 500 aa overlap (33-530:111-610)
10 20 30 40 50 60
pF1KE0 MPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPK--KQIQFADDMQEFTKFPTKTGR
:::.::. :.:::::. :::.: ::: ::
NP_001 PQASAMKRSDPHHQHQRHRDGGEALVSPDGTVTEAPRTVKKIQFADQKQEFNKRPTKIGR
90 100 110 120 130 140
70 80 90 100 110 120
pF1KE0 RSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREI
::::::::::::::::::::::::::::.:::.::: ::::::.::::::::::::::::
NP_001 RSLSRSISQSSTDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREI
150 160 170 180 190 200
130 140 150 160 170 180
pF1KE0 EIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIY
:::::.: ::..:::::::::::::::::::::::::::::.::: ::::::::.:::::
NP_001 EIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIY
210 220 230 240 250 260
190 200 210 220 230 240
pF1KE0 STQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKK
:: :::::::::.: :::::::::::::::::::::..::: :::::::::::::.:::
NP_001 STLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKK
270 280 290 300 310 320
250 260 270 280 290 300
pF1KE0 YPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
:::.::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
330 340 350 360 370 380
310 320 330 340 350 360
pF1KE0 LKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKL
::::::.:::::::::::::::::::::::::.:.:::.:::::::::::::::::.:::
NP_001 LKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKL
390 400 410 420 430 440
370 380 390 400 410 420
pF1KE0 NEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVR
::::::::.:::::::::::::::::::::::::::::::::::::.:::::::::::::
NP_001 NEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVR
450 460 470 480 490 500
430 440 450 460 470 480
pF1KE0 SQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQVDHVIWPDGKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
510 520 530 540 550 560
490 500 510 520 530
pF1KE0 VYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
::::::::::::::::::.::::::::::.::::::::::::::::::::
NP_001 VYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
570 580 590 600 610
>>NP_001124194 (OMIM: 616520) adenosylhomocysteinase 3 i (508 aa)
initn: 3107 init1: 3107 opt: 3110 Z-score: 3534.0 bits: 663.5 E(85289): 4.2e-190
Smith-Waterman score: 3110; 90.5% identity (97.2% similar) in 504 aa overlap (27-530:5-508)
10 20 30 40 50 60
pF1KE0 MSMPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGR
: ..... ... : ::::::. :::.: ::: ::
NP_001 MLGSKKKYIVNGNSGIKAQIQFADQKQEFNKRPTKIGR
10 20 30
70 80 90 100 110 120
pF1KE0 RSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREI
::::::::::::::::::::::::::::.:::.::: ::::::.::::::::::::::::
NP_001 RSLSRSISQSSTDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREI
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE0 EIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIY
:::::.: ::..:::::::::::::::::::::::::::::.::: ::::::::.:::::
NP_001 EIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIY
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE0 STQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKK
:: :::::::::.: :::::::::::::::::::::..::: :::::::::::::.:::
NP_001 STLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKK
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE0 YPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
:::.::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE0 LKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKL
::::::.:::::::::::::::::::::::::.:.:::.:::::::::::::::::.:::
NP_001 LKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKL
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE0 NEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVR
::::::::.:::::::::::::::::::::::::::::::::::::.:::::::::::::
NP_001 NEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVR
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE0 SQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQVDHVIWPDGKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
400 410 420 430 440 450
490 500 510 520 530
pF1KE0 VYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
::::::::::::::::::.::::::::::.::::::::::::::::::::
NP_001 VYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
460 470 480 490 500
>>NP_001124195 (OMIM: 616520) adenosylhomocysteinase 3 i (508 aa)
initn: 3103 init1: 3103 opt: 3103 Z-score: 3526.1 bits: 662.1 E(85289): 1.2e-189
Smith-Waterman score: 3103; 92.1% identity (97.8% similar) in 493 aa overlap (38-530:16-508)
10 20 30 40 50 60
pF1KE0 PLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGRRSLSRSI
:. .:::::. :::.: ::: :::::::::
NP_001 MEKWDGNEGTSAFHMPEWMIQFADQKQEFNKRPTKIGRRSLSRSI
10 20 30 40
70 80 90 100 110 120
pF1KE0 SQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDM
:::::::::::::::::::::.:::.::: ::::::.:::::::::::::::::::::.:
NP_001 SQSSTDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREIEIAEQEM
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 SALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVA
::..:::::::::::::::::::::::::::::.::: ::::::::.::::::: ::::
NP_001 PALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEVA
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 AALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKK
:::::.: :::::::::::::::::::::..::: :::::::::::::.::::::.:::
NP_001 AALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFKK
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 IRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDV
:.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_001 IKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDM
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE0 MFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQV
:::::::::::::::::::::::::.:.:::.:::::::::::::::::.::::::::::
NP_001 MFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQV
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE0 DVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVI
:.:::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
NP_001 DIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVI
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE0 WPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKK
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WPDGKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKK
410 420 430 440 450 460
490 500 510 520 530
pF1KE0 MDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
:::::::::::.::::::::::.::::::::::::::::::::
NP_001 MDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
470 480 490 500
530 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 14:39:14 2016 done: Thu Nov 3 14:39:15 2016
Total Scan time: 8.120 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]