Result of FASTA (omim) for
pFN21AE0590
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0590, 435 aa
1>>>pF1KE0590 435 - 435 aa - 435 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1091+/-0.000307; mu= 20.1456+/- 0.019
mean_var=82.6748+/-17.145, 0's: 0 Z-trim(117.4): 11 B-trim: 844 in 1/53
Lambda= 0.141055
statistics sampled from 29450 (29460) to 29450 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.345), width: 16
Scan time: 8.420
The best scores are: opt bits E(85289)
NP_071908 (OMIM: 612895) nucleoredoxin isoform 1 [ ( 435) 2921 603.9 2.6e-172
XP_005256815 (OMIM: 612895) PREDICTED: nucleoredox ( 322) 2109 438.5 1.2e-122
NP_001192248 (OMIM: 612895) nucleoredoxin isoform ( 327) 2106 437.9 1.8e-122
XP_016880438 (OMIM: 612895) PREDICTED: nucleoredox ( 321) 1869 389.7 5.8e-108
XP_005256813 (OMIM: 612895) PREDICTED: nucleoredox ( 375) 1861 388.1 2e-107
NP_001155097 (OMIM: 615299) nucleoredoxin-like pro ( 156) 235 56.9 4.3e-08
>>NP_071908 (OMIM: 612895) nucleoredoxin isoform 1 [Homo (435 aa)
initn: 2921 init1: 2921 opt: 2921 Z-score: 3214.5 bits: 603.9 E(85289): 2.6e-172
Smith-Waterman score: 2921; 100.0% identity (100.0% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KE0 MSGFLEELLGEKLVTGGGEEVDVHSLGARGISLLGLYFGCSLSAPCAQLSASLAAFYGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MSGFLEELLGEKLVTGGGEEVDVHSLGARGISLLGLYFGCSLSAPCAQLSASLAAFYGRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 RGDAAAGPGPGAGAGAAAEPEPRRRLEIVFVSSDQDQRQWQDFVRDMPWLALPYKEKHRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 RGDAAAGPGPGAGAGAAAEPEPRRRLEIVFVSSDQDQRQWQDFVRDMPWLALPYKEKHRK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LKLWNKYRISNIPSLIFLDATTGKVVCRNGLLVIRDDPEGLEFPWGPKPFREVIAGPLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LKLWNKYRISNIPSLIFLDATTGKVVCRNGLLVIRDDPEGLEFPWGPKPFREVIAGPLLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 NNGQSLESSSLEGSHVGVYFSAHWCPPCRSLTRVLVESYRKIKEAGQNFEIIFVSADRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 NNGQSLESSSLEGSHVGVYFSAHWCPPCRSLTRVLVESYRKIKEAGQNFEIIFVSADRSE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ESFKQYFSEMPWLAVPYTDEARRSRLNRLYGIQGIPTLIMLDPQGEVITRQGRVEVLNDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 ESFKQYFSEMPWLAVPYTDEARRSRLNRLYGIQGIPTLIMLDPQGEVITRQGRVEVLNDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 DCREFPWHPKPVLELSDSNAAQLNEGPCLVLFVDSEDDGESEAAKQLIQPIAEKIIAKYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 DCREFPWHPKPVLELSDSNAAQLNEGPCLVLFVDSEDDGESEAAKQLIQPIAEKIIAKYK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 AKEEEAPLLFFVAGEDDMTDSLRDYTNLPEAAPLLTILDMSARAKYVMDVEEITPAIVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 AKEEEAPLLFFVAGEDDMTDSLRDYTNLPEAAPLLTILDMSARAKYVMDVEEITPAIVEA
370 380 390 400 410 420
430
pF1KE0 FVNDFLAEKLKPEPI
:::::::::::::::
NP_071 FVNDFLAEKLKPEPI
430
>>XP_005256815 (OMIM: 612895) PREDICTED: nucleoredoxin i (322 aa)
initn: 2109 init1: 2109 opt: 2109 Z-score: 2323.2 bits: 438.5 E(85289): 1.2e-122
Smith-Waterman score: 2109; 98.4% identity (99.4% similar) in 321 aa overlap (115-435:2-322)
90 100 110 120 130 140
pF1KE0 RLEIVFVSSDQDQRQWQDFVRDMPWLALPYKEKHRKLKLWNKYRISNIPSLIFLDATTGK
.: . .::::::::::::::::::::::::
XP_005 MQELRNSLKLWNKYRISNIPSLIFLDATTGK
10 20 30
150 160 170 180 190 200
pF1KE0 VVCRNGLLVIRDDPEGLEFPWGPKPFREVIAGPLLRNNGQSLESSSLEGSHVGVYFSAHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVCRNGLLVIRDDPEGLEFPWGPKPFREVIAGPLLRNNGQSLESSSLEGSHVGVYFSAHW
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE0 CPPCRSLTRVLVESYRKIKEAGQNFEIIFVSADRSEESFKQYFSEMPWLAVPYTDEARRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CPPCRSLTRVLVESYRKIKEAGQNFEIIFVSADRSEESFKQYFSEMPWLAVPYTDEARRS
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE0 RLNRLYGIQGIPTLIMLDPQGEVITRQGRVEVLNDEDCREFPWHPKPVLELSDSNAAQLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLNRLYGIQGIPTLIMLDPQGEVITRQGRVEVLNDEDCREFPWHPKPVLELSDSNAAQLN
160 170 180 190 200 210
330 340 350 360 370 380
pF1KE0 EGPCLVLFVDSEDDGESEAAKQLIQPIAEKIIAKYKAKEEEAPLLFFVAGEDDMTDSLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGPCLVLFVDSEDDGESEAAKQLIQPIAEKIIAKYKAKEEEAPLLFFVAGEDDMTDSLRD
220 230 240 250 260 270
390 400 410 420 430
pF1KE0 YTNLPEAAPLLTILDMSARAKYVMDVEEITPAIVEAFVNDFLAEKLKPEPI
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YTNLPEAAPLLTILDMSARAKYVMDVEEITPAIVEAFVNDFLAEKLKPEPI
280 290 300 310 320
>>NP_001192248 (OMIM: 612895) nucleoredoxin isoform 2 [H (327 aa)
initn: 2105 init1: 2105 opt: 2106 Z-score: 2319.8 bits: 437.9 E(85289): 1.8e-122
Smith-Waterman score: 2106; 98.8% identity (99.1% similar) in 321 aa overlap (118-435:7-327)
90 100 110 120 130 140
pF1KE0 IVFVSSDQDQRQWQDFVRDMPWLALPYKEKHRK---LKLWNKYRISNIPSLIFLDATTGK
::. ::::::::::::::::::::::::
NP_001 MADVSLHRNPATLKLWNKYRISNIPSLIFLDATTGK
10 20 30
150 160 170 180 190 200
pF1KE0 VVCRNGLLVIRDDPEGLEFPWGPKPFREVIAGPLLRNNGQSLESSSLEGSHVGVYFSAHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVCRNGLLVIRDDPEGLEFPWGPKPFREVIAGPLLRNNGQSLESSSLEGSHVGVYFSAHW
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE0 CPPCRSLTRVLVESYRKIKEAGQNFEIIFVSADRSEESFKQYFSEMPWLAVPYTDEARRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPPCRSLTRVLVESYRKIKEAGQNFEIIFVSADRSEESFKQYFSEMPWLAVPYTDEARRS
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE0 RLNRLYGIQGIPTLIMLDPQGEVITRQGRVEVLNDEDCREFPWHPKPVLELSDSNAAQLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLNRLYGIQGIPTLIMLDPQGEVITRQGRVEVLNDEDCREFPWHPKPVLELSDSNAAQLN
160 170 180 190 200 210
330 340 350 360 370 380
pF1KE0 EGPCLVLFVDSEDDGESEAAKQLIQPIAEKIIAKYKAKEEEAPLLFFVAGEDDMTDSLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGPCLVLFVDSEDDGESEAAKQLIQPIAEKIIAKYKAKEEEAPLLFFVAGEDDMTDSLRD
220 230 240 250 260 270
390 400 410 420 430
pF1KE0 YTNLPEAAPLLTILDMSARAKYVMDVEEITPAIVEAFVNDFLAEKLKPEPI
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTNLPEAAPLLTILDMSARAKYVMDVEEITPAIVEAFVNDFLAEKLKPEPI
280 290 300 310 320
>>XP_016880438 (OMIM: 612895) PREDICTED: nucleoredoxin i (321 aa)
initn: 1869 init1: 1869 opt: 1869 Z-score: 2059.2 bits: 389.7 E(85289): 5.8e-108
Smith-Waterman score: 1869; 100.0% identity (100.0% similar) in 274 aa overlap (1-274:1-274)
10 20 30 40 50 60
pF1KE0 MSGFLEELLGEKLVTGGGEEVDVHSLGARGISLLGLYFGCSLSAPCAQLSASLAAFYGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGFLEELLGEKLVTGGGEEVDVHSLGARGISLLGLYFGCSLSAPCAQLSASLAAFYGRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 RGDAAAGPGPGAGAGAAAEPEPRRRLEIVFVSSDQDQRQWQDFVRDMPWLALPYKEKHRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGDAAAGPGPGAGAGAAAEPEPRRRLEIVFVSSDQDQRQWQDFVRDMPWLALPYKEKHRK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LKLWNKYRISNIPSLIFLDATTGKVVCRNGLLVIRDDPEGLEFPWGPKPFREVIAGPLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLWNKYRISNIPSLIFLDATTGKVVCRNGLLVIRDDPEGLEFPWGPKPFREVIAGPLLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 NNGQSLESSSLEGSHVGVYFSAHWCPPCRSLTRVLVESYRKIKEAGQNFEIIFVSADRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNGQSLESSSLEGSHVGVYFSAHWCPPCRSLTRVLVESYRKIKEAGQNFEIIFVSADRSE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ESFKQYFSEMPWLAVPYTDEARRSRLNRLYGIQGIPTLIMLDPQGEVITRQGRVEVLNDE
::::::::::::::::::::::::::::::::::
XP_016 ESFKQYFSEMPWLAVPYTDEARRSRLNRLYGIQGAVRTPEASTAWQEEQQLLQQVDQGPV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 DCREFPWHPKPVLELSDSNAAQLNEGPCLVLFVDSEDDGESEAAKQLIQPIAEKIIAKYK
XP_016 PSVTTAWLGDPHPYCNHCLAG
310 320
>>XP_005256813 (OMIM: 612895) PREDICTED: nucleoredoxin i (375 aa)
initn: 2489 init1: 1861 opt: 1861 Z-score: 2049.6 bits: 388.1 E(85289): 2e-107
Smith-Waterman score: 2373; 86.2% identity (86.2% similar) in 435 aa overlap (1-435:1-375)
10 20 30 40 50 60
pF1KE0 MSGFLEELLGEKLVTGGGEEVDVHSLGARGISLLGLYFGCSLSAPCAQLSASLAAFYGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGFLEELLGEKLVTGGGEEVDVHSLGARGISLLGLYFGCSLSAPCAQLSASLAAFYGRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 RGDAAAGPGPGAGAGAAAEPEPRRRLEIVFVSSDQDQRQWQDFVRDMPWLALPYKEKHRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGDAAAGPGPGAGAGAAAEPEPRRRLEIVFVSSDQDQRQWQDFVRDMPWLALPYKEKHRK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LKLWNKYRISNIPSLIFLDATTGKVVCRNGLLVIRDDPEGLEFPWGPKPFREVIAGPLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKLWNKYRISNIPSLIFLDATTGKVVCRNGLLVIRDDPEGLEFPWGPKPFREVIAGPLLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 NNGQSLESSSLEGSHVGVYFSAHWCPPCRSLTRVLVESYRKIKEAGQNFEIIFVSADRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NNGQSLESSSLEGSHVGVYFSAHWCPPCRSLTRVLVESYRKIKEAGQNFEIIFVSADRSE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ESFKQYFSEMPWLAVPYTDEARRSRLNRLYGIQGIPTLIMLDPQGEVITRQGRVEVLNDE
:::::::::::::::::::::::::::::::::
XP_005 ESFKQYFSEMPWLAVPYTDEARRSRLNRLYGIQ---------------------------
250 260 270
310 320 330 340 350 360
pF1KE0 DCREFPWHPKPVLELSDSNAAQLNEGPCLVLFVDSEDDGESEAAKQLIQPIAEKIIAKYK
:::::::::::::::::::::::::::
XP_005 ---------------------------------DSEDDGESEAAKQLIQPIAEKIIAKYK
280 290 300
370 380 390 400 410 420
pF1KE0 AKEEEAPLLFFVAGEDDMTDSLRDYTNLPEAAPLLTILDMSARAKYVMDVEEITPAIVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKEEEAPLLFFVAGEDDMTDSLRDYTNLPEAAPLLTILDMSARAKYVMDVEEITPAIVEA
310 320 330 340 350 360
430
pF1KE0 FVNDFLAEKLKPEPI
:::::::::::::::
XP_005 FVNDFLAEKLKPEPI
370
>>NP_001155097 (OMIM: 615299) nucleoredoxin-like protein (156 aa)
initn: 241 init1: 72 opt: 235 Z-score: 266.2 bits: 56.9 E(85289): 4.3e-08
Smith-Waterman score: 235; 34.4% identity (67.2% similar) in 125 aa overlap (178-296:10-133)
150 160 170 180 190 200
pF1KE0 RNGLLVIRDDPEGLEFPWGPKPFREVIAGPLLRNNGQSLES-SSLEGSHVGVYFSAHWCP
:. .: ..:. ..:... :..::.: :
NP_001 MVDILGERHLVTCKGATVEAEAALQNKVVALYFAAARCA
10 20 30
210 220 230 240 250 260
pF1KE0 PCRSLTRVLVESYRK-IKEAGQN--FEIIFVSADRSEESFKQYFSEM--PWLAVPYTDEA
: :..: .: . : . :: . ::..::::: : . . ... :. :::.:. :
NP_001 PSRDFTPLLCDFYTALVAEARRPAPFEVVFVSADGSSQEMLDFMRELHGAWLALPFHDP-
40 50 60 70 80 90
270 280 290 300 310 320
pF1KE0 RRSRLNRLYGIQGIPTLIMLDPQGEVITRQGRVEVLNDEDCREFPWHPKPVLELSDSNAA
: .: . :.. .:: :... .::::: .:: ..
NP_001 YRHELRKRYNVTAIPKLVIVKQNGEVITNKGRKQIRERGLACFQDWVEAADIFQNFSV
100 110 120 130 140 150
330 340 350 360 370 380
pF1KE0 QLNEGPCLVLFVDSEDDGESEAAKQLIQPIAEKIIAKYKAKEEEAPLLFFVAGEDDMTDS
435 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 14:26:00 2016 done: Mon Nov 7 14:26:02 2016
Total Scan time: 8.420 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]