Result of FASTA (ccds) for
pFN21AB6915
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6915, 205 aa
1>>>pF1KB6915 205 - 205 aa - 205 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2665+/-0.000833; mu= 13.5090+/- 0.050
mean_var=69.2611+/-13.781, 0's: 0 Z-trim(107.8): 180 B-trim: 314 in 1/48
Lambda= 0.154110
statistics sampled from 9595 (9791) to 9595 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.301), width: 16
Scan time: 2.030
The best scores are: opt bits E(32554)
CCDS33191.1 RHOQ gene_id:23433|Hs108|chr2 ( 205) 1392 318.2 2.3e-87
CCDS9757.1 RHOJ gene_id:57381|Hs108|chr14 ( 214) 1032 238.1 2.9e-63
CCDS222.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 880 204.3 4e-53
CCDS221.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 879 204.1 4.6e-53
CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 ( 192) 831 193.4 7.6e-50
CCDS11798.1 RAC3 gene_id:5881|Hs108|chr17 ( 192) 829 193.0 1e-49
CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 ( 192) 802 187.0 6.6e-48
CCDS7748.1 RHOG gene_id:391|Hs108|chr11 ( 191) 724 169.6 1.1e-42
CCDS10068.1 RHOV gene_id:171177|Hs108|chr15 ( 236) 695 163.2 1.1e-40
CCDS1699.1 RHOB gene_id:388|Hs108|chr2 ( 196) 689 161.9 2.5e-40
CCDS1575.1 RHOU gene_id:58480|Hs108|chr1 ( 258) 683 160.6 7.7e-40
CCDS2795.1 RHOA gene_id:387|Hs108|chr3 ( 193) 679 159.6 1.1e-39
CCDS854.1 RHOC gene_id:389|Hs108|chr1 ( 193) 670 157.6 4.5e-39
CCDS9222.1 RHOF gene_id:54509|Hs108|chr12 ( 211) 601 142.3 2e-34
CCDS8155.1 RHOD gene_id:29984|Hs108|chr11 ( 210) 582 138.1 3.8e-33
CCDS82775.1 RHOA gene_id:387|Hs108|chr3 ( 187) 575 136.5 1e-32
CCDS2190.1 RND3 gene_id:390|Hs108|chr2 ( 244) 544 129.7 1.5e-30
CCDS11452.1 RND2 gene_id:8153|Hs108|chr17 ( 227) 504 120.8 6.7e-28
CCDS3458.1 RHOH gene_id:399|Hs108|chr4 ( 191) 495 118.7 2.3e-27
CCDS5349.1 RAC1 gene_id:5879|Hs108|chr7 ( 211) 469 113.0 1.4e-25
CCDS8771.1 RND1 gene_id:27289|Hs108|chr12 ( 232) 446 107.9 5.2e-24
CCDS6034.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 727) 307 77.3 2.6e-14
CCDS55211.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 734) 307 77.3 2.6e-14
CCDS55210.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 749) 307 77.3 2.7e-14
CCDS7261.1 RHOBTB1 gene_id:9886|Hs108|chr10 ( 696) 304 76.6 4e-14
CCDS5460.1 RALA gene_id:5898|Hs108|chr7 ( 206) 269 68.5 3.3e-12
CCDS8703.1 KRAS gene_id:3845|Hs108|chr12 ( 189) 261 66.7 1.1e-11
CCDS46306.1 RAB1A gene_id:5861|Hs108|chr2 ( 205) 260 66.5 1.3e-11
CCDS2131.1 RALB gene_id:5899|Hs108|chr2 ( 206) 256 65.6 2.4e-11
CCDS7699.1 HRAS gene_id:3265|Hs108|chr11 ( 170) 254 65.1 2.8e-11
CCDS7698.1 HRAS gene_id:3265|Hs108|chr11 ( 189) 254 65.1 3.1e-11
CCDS31613.1 RAB1B gene_id:81876|Hs108|chr11 ( 201) 254 65.2 3.3e-11
CCDS14632.1 RAP2C gene_id:57826|Hs108|chrX ( 183) 253 64.9 3.5e-11
CCDS8702.1 KRAS gene_id:3845|Hs108|chr12 ( 188) 252 64.7 4.2e-11
CCDS3170.1 RAP2B gene_id:5912|Hs108|chr3 ( 183) 250 64.2 5.6e-11
CCDS9485.1 RAP2A gene_id:5911|Hs108|chr13 ( 183) 250 64.2 5.6e-11
CCDS877.1 NRAS gene_id:4893|Hs108|chr1 ( 189) 249 64.0 6.7e-11
CCDS1720.1 RAB10 gene_id:10890|Hs108|chr2 ( 200) 249 64.0 7e-11
>>CCDS33191.1 RHOQ gene_id:23433|Hs108|chr2 (205 aa)
initn: 1392 init1: 1392 opt: 1392 Z-score: 1682.1 bits: 318.2 E(32554): 2.3e-87
Smith-Waterman score: 1392; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205)
10 20 30 40 50 60
pF1KB6 MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 TQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 TQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAII
130 140 150 160 170 180
190 200
pF1KB6 AILTPKKHTVKKRIGSRCINCCLIT
:::::::::::::::::::::::::
CCDS33 AILTPKKHTVKKRIGSRCINCCLIT
190 200
>>CCDS9757.1 RHOJ gene_id:57381|Hs108|chr14 (214 aa)
initn: 1041 init1: 1013 opt: 1032 Z-score: 1249.2 bits: 238.1 E(32554): 2.9e-63
Smith-Waterman score: 1032; 79.6% identity (90.3% similar) in 196 aa overlap (9-204:21-213)
10 20 30 40
pF1KB6 MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAV
::::::::::::::::::::::::::::::::::::::::
CCDS97 MNCKEGTDSSCGCRGNDEKKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 SVTVGGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELK
.:::::::.:::::::::::::..::::::: :::::::::::::::..::.::::::::
CCDS97 TVTVGGKQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELK
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB6 EYAPNVPFLLIGTQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQ
. :.::..:::::::::::::::::: :::::. :.: :::: ::: ::.:::::::
CCDS97 DCMPHVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQ
130 140 150 160 170 180
170 180 190 200
pF1KB6 KGLKTVFDEAIIAILTPKKHTVKKRIGSRCINCCLIT
::::.::::::..:. ::: ::. :. .:: :
CCDS97 KGLKAVFDEAILTIFHPKK---KKKRCSEGHSCCSII
190 200 210
>>CCDS222.1 CDC42 gene_id:998|Hs108|chr1 (191 aa)
initn: 888 init1: 868 opt: 880 Z-score: 1067.3 bits: 204.3 E(32554): 4e-53
Smith-Waterman score: 880; 64.9% identity (84.5% similar) in 194 aa overlap (10-203:4-190)
10 20 30 40 50 60
pF1KB6 MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLG
.::::::::::::::::.::... :: ::::::::.:::.: .::. : ::
CCDS22 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLG
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 LYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIG
:.:::::::::::::::::.:::::.:::::.:.::.::::.::::. .. :..::::.:
CCDS22 LFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 TQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAII
:::::::::.:. .: :.::: : ..:::... : :::::::::.:::.::::::.
CCDS22 TQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQRGLKNVFDEAIL
120 130 140 150 160 170
190 200
pF1KB6 AILTPKKHTVKKRIGSRCINCCLIT
: : : . :.. ::.
CCDS22 AALEPPETQPKRK-------CCIF
180 190
>>CCDS221.1 CDC42 gene_id:998|Hs108|chr1 (191 aa)
initn: 891 init1: 871 opt: 879 Z-score: 1066.1 bits: 204.1 E(32554): 4.6e-53
Smith-Waterman score: 879; 67.4% identity (86.3% similar) in 190 aa overlap (10-199:4-189)
10 20 30 40 50 60
pF1KB6 MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLG
.::::::::::::::::.::... :: ::::::::.:::.: .::. : ::
CCDS22 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLG
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 LYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIG
:.:::::::::::::::::.:::::.:::::.:.::.::::.::::. .. :..::::.:
CCDS22 LFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 TQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAII
:::::::::.:. .: :.::: : ..:::... : :::::::::::::.::::::.
CCDS22 TQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAIL
120 130 140 150 160 170
190 200
pF1KB6 AILTPKKHTVKKRIGSRCINCCLIT
: : : . :.: ::.
CCDS22 AALEPPEPK-KSR---RCVLL
180 190
>>CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 (192 aa)
initn: 826 init1: 826 opt: 831 Z-score: 1008.4 bits: 193.4 E(32554): 7.6e-50
Smith-Waterman score: 831; 64.2% identity (83.7% similar) in 190 aa overlap (10-199:4-190)
10 20 30 40 50 60
pF1KB6 MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLG
.::::::::::::::::.::...::: ::.:::::.:...: : :: ::
CCDS53 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLG
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 LYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIG
:.:::::::::::::::::.:::::::::.:.::::.::. .: ::.... ::.:..:.:
CCDS53 LWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 TQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAII
:..::::: :. .:.. : :: :: .:::::: :.:::::::.::::::::::
CCDS53 TKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIR
120 130 140 150 160 170
190 200
pF1KB6 AILTPKKHTVKKRIGSRCINCCLIT
:.: : :::: .:.
CCDS53 AVLCPPP--VKKR-KRKCLLL
180 190
>>CCDS11798.1 RAC3 gene_id:5881|Hs108|chr17 (192 aa)
initn: 849 init1: 817 opt: 829 Z-score: 1006.0 bits: 193.0 E(32554): 1e-49
Smith-Waterman score: 829; 64.6% identity (83.6% similar) in 189 aa overlap (10-198:4-189)
10 20 30 40 50 60
pF1KB6 MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLG
.::::::::::::::::.::...::: ::.:::::.:...: : :: ::
CCDS11 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLG
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 LYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIG
:.:::::::::::::::::.:::::::::.:.::::.::. .: ::.... :..:.::.:
CCDS11 LWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 TQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAII
:..::::: :. :: : : :: :: .:.:::. :.:::::::.::::::::::
CCDS11 TKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIR
120 130 140 150 160 170
190 200
pF1KB6 AILTPKKHTVKKRIGSRCINCCLIT
:.: : ::: :..:
CCDS11 AVLCPPP--VKKP-GKKCTVF
180 190
>>CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 (192 aa)
initn: 838 init1: 800 opt: 802 Z-score: 973.5 bits: 187.0 E(32554): 6.6e-48
Smith-Waterman score: 802; 62.0% identity (83.4% similar) in 187 aa overlap (10-196:4-190)
10 20 30 40 50 60
pF1KB6 MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLG
.::::::::::::::::.::...::: ::.:::::.:...: : .: ::
CCDS13 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLG
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 LYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIG
:.:::::::::::::::::.:::::::::.:.:::..::. .: ::.... :..:..:.:
CCDS13 LWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 TQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAII
:..::::: :. .:.. : :: :: ::::: . :.:::::::.::::::::::
CCDS13 TKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIR
120 130 140 150 160 170
190 200
pF1KB6 AILTPKKHTVKKRIGSRCINCCLIT
:.: :. .:: :
CCDS13 AVLCPQPTRQQKRACSLL
180 190
>>CCDS7748.1 RHOG gene_id:391|Hs108|chr11 (191 aa)
initn: 748 init1: 714 opt: 724 Z-score: 879.8 bits: 169.6 E(32554): 1.1e-42
Smith-Waterman score: 724; 56.8% identity (81.1% similar) in 190 aa overlap (10-199:4-189)
10 20 30 40 50 60
pF1KB6 MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLG
.::::::::::::::::. :...:::.::.:::::.:... .: :. :.
CCDS77 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLN
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 LYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIG
:.::::::.::::: ::::.:.::.::::...: :..::...: ::. .. :.::.::.:
CCDS77 LWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 TQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAII
:. ::: .: :: ::... . :: .::: :::.: : :.::::: : :.: :: ::.
CCDS77 TKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVR
120 130 140 150 160 170
190 200
pF1KB6 AILTPKKHTVKKRIGSRCINCCLIT
:.:.: : :: : ::
CCDS77 AVLNP---TPIKR-GRSCILL
180 190
>>CCDS10068.1 RHOV gene_id:171177|Hs108|chr15 (236 aa)
initn: 667 init1: 509 opt: 695 Z-score: 843.7 bits: 163.2 E(32554): 1.1e-40
Smith-Waterman score: 695; 52.7% identity (75.1% similar) in 201 aa overlap (5-198:27-227)
10 20 30
pF1KB6 MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEY
: : .:::.::::::::. :..::. ...: .:
CCDS10 MPPRELSEAEPPPLRAPTPPPRRRSAPPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARY
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 VPTVFDHYAVSVTVGGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQN
::..: ..:.: : : . :.:::::::.:::: : :: ::::: :::::.:.::::
CCDS10 RPTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQN
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 VKEEWVPELKEYAPNVPFLLIGTQIDLRDDPKTLARLNDM-KEKPICVEQGQKLAKEIGA
. :.:.::.. . :..: ::.::: ::::: ..: .:.. .: :. :.: ::..: :
CCDS10 ITEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRA
130 140 150 160 170 180
160 170 180 190 200
pF1KB6 CCYVECSALTQKGLKTVFDEAIIAILTPKKHTVKK------RIGSRCINCCLIT
:::.::::::::.:: ::: ::.. . : . :: : :::
CCDS10 CCYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV
190 200 210 220 230
>>CCDS1699.1 RHOB gene_id:388|Hs108|chr2 (196 aa)
initn: 699 init1: 637 opt: 689 Z-score: 837.6 bits: 161.9 E(32554): 2.5e-40
Smith-Waterman score: 689; 52.0% identity (78.0% similar) in 200 aa overlap (7-204:3-195)
10 20 30 40 50 60
pF1KB6 MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLG
:. : ::::::: ::::::. ...: ::: ::::::..:.... : ::: :.
CCDS16 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELA
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 LYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIG
:.::::::::::::::::: :::.:.:::: .: :..:. :.::::.:.. ::::..:..
CCDS16 LWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 TQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAII
.. :::.: .. ..: ::..:. ...:. .: .: : :.:::: :..:.. ::. :
CCDS16 NKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATR
120 130 140 150 160 170
190 200
pF1KB6 AILTPKKHTVKKRIGSR--CINCCLIT
: : .:: ::. ::::: .
CCDS16 AAL-------QKRYGSQNGCINCCKVL
180 190
205 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:54:19 2016 done: Sat Nov 5 18:54:20 2016
Total Scan time: 2.030 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]