Result of FASTA (ccds) for
pFN21AE0755
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0755, 329 aa
1>>>pF1KE0755 329 - 329 aa - 329 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2831+/-0.000692; mu= 16.9533+/- 0.042
mean_var=74.6678+/-14.768, 0's: 0 Z-trim(111.0): 11 B-trim: 38 in 1/51
Lambda= 0.148425
statistics sampled from 12042 (12051) to 12042 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.733), E-opt: 0.2 (0.37), width: 16
Scan time: 2.890
The best scores are: opt bits E(32554)
CCDS47350.1 DOK3 gene_id:79930|Hs108|chr5 ( 330) 2241 488.7 2.8e-138
CCDS78098.1 DOK3 gene_id:79930|Hs108|chr5 ( 440) 1487 327.3 1.4e-89
CCDS4426.1 DOK3 gene_id:79930|Hs108|chr5 ( 496) 1487 327.3 1.5e-89
CCDS47349.1 DOK3 gene_id:79930|Hs108|chr5 ( 228) 1364 300.8 7.1e-82
CCDS1954.1 DOK1 gene_id:1796|Hs108|chr2 ( 481) 504 116.8 3.5e-26
CCDS6016.1 DOK2 gene_id:9046|Hs108|chr8 ( 412) 485 112.7 5.1e-25
CCDS82474.1 DOK1 gene_id:1796|Hs108|chr2 ( 177) 358 85.3 4.1e-17
>>CCDS47350.1 DOK3 gene_id:79930|Hs108|chr5 (330 aa)
initn: 1957 init1: 1957 opt: 2241 Z-score: 2596.1 bits: 488.7 E(32554): 2.8e-138
Smith-Waterman score: 2241; 99.4% identity (99.4% similar) in 330 aa overlap (1-329:1-330)
10 20 30 40 50 60
pF1KE0 MDPLETPIKDGILYQQHVKFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MDPLETPIKDGILYQQHVKFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AGPGRRGERRVIRLADCVSVLPADGESCPRDTGAFLLTTTERSHLLAAQHRQAWMGPICQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 AGPGRRGERRVIRLADCVSVLPADGESCPRDTGAFLLTTTERSHLLAAQHRQAWMGPICQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LLVLGPDAIQLREAKGTQALYSWPYHFLRKFGSDKILLGTPGVSLLICKGERTDDVSGII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LLVLGPDAIQLREAKGTQALYSWPYHFLRKFGSDKILLGTPGVSLLICKGERTDDVSGII
190 200 210 220 230 240
250 260 270 280 290
pF1KE0 LDESLLRAYSVPGAGGHSRVQDSLGPVLREPTFQGERSFLKTSMLRSL-CSCSWRHPRSQ
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
CCDS47 LDESLLRAYSVPGAGGHSRVQDSLGPVLREPTFQGERSFLKTSMLRSLLCSCSWRHPRSQ
250 260 270 280 290 300
300 310 320
pF1KE0 PCTQASCLQGSDCPAPHRNSTSAAHTLGTS
: ::::::::::::::::::::::::::::
CCDS47 PRTQASCLQGSDCPAPHRNSTSAAHTLGTS
310 320 330
>>CCDS78098.1 DOK3 gene_id:79930|Hs108|chr5 (440 aa)
initn: 1534 init1: 1487 opt: 1487 Z-score: 1721.8 bits: 327.3 E(32554): 1.4e-89
Smith-Waterman score: 1487; 100.0% identity (100.0% similar) in 215 aa overlap (1-215:1-215)
10 20 30 40 50 60
pF1KE0 MDPLETPIKDGILYQQHVKFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 MDPLETPIKDGILYQQHVKFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AGPGRRGERRVIRLADCVSVLPADGESCPRDTGAFLLTTTERSHLLAAQHRQAWMGPICQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 AGPGRRGERRVIRLADCVSVLPADGESCPRDTGAFLLTTTERSHLLAAQHRQAWMGPICQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 LAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LLVLGPDAIQLREAKGTQALYSWPYHFLRKFGSDKILLGTPGVSLLICKGERTDDVSGII
:::::::::::::::::::::::::::::::::::
CCDS78 LLVLGPDAIQLREAKGTQALYSWPYHFLRKFGSDKGVFSFEAGRRCHSGEGLFAFSTPCA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LDESLLRAYSVPGAGGHSRVQDSLGPVLREPTFQGERSFLKTSMLRSLCSCSWRHPRSQP
CCDS78 PDLCRAVAGAIARQRERLPELTRPQPCPLPRATSLPSLDTPGELREMPPGPEPPTSRKMH
250 260 270 280 290 300
>>CCDS4426.1 DOK3 gene_id:79930|Hs108|chr5 (496 aa)
initn: 1534 init1: 1487 opt: 1487 Z-score: 1721.0 bits: 327.3 E(32554): 1.5e-89
Smith-Waterman score: 1487; 100.0% identity (100.0% similar) in 215 aa overlap (1-215:57-271)
10 20 30
pF1KE0 MDPLETPIKDGILYQQHVKFGKKCWRKVWA
::::::::::::::::::::::::::::::
CCDS44 GQKGKCEEFPSSLSSVSPGLEAAALLLAVTMDPLETPIKDGILYQQHVKFGKKCWRKVWA
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE0 LLYAGGPSGVARLESWEVRDGGLGAAGDRSAGPGRRGERRVIRLADCVSVLPADGESCPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LLYAGGPSGVARLESWEVRDGGLGAAGDRSAGPGRRGERRVIRLADCVSVLPADGESCPR
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE0 DTGAFLLTTTERSHLLAAQHRQAWMGPICQLAFPGTGEASSGSTDAQSPKRGLVPMEENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DTGAFLLTTTERSHLLAAQHRQAWMGPICQLAFPGTGEASSGSTDAQSPKRGLVPMEENS
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE0 IYSSWQEVGEFPVVVQRTEAATRCQLKGPALLVLGPDAIQLREAKGTQALYSWPYHFLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IYSSWQEVGEFPVVVQRTEAATRCQLKGPALLVLGPDAIQLREAKGTQALYSWPYHFLRK
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE0 FGSDKILLGTPGVSLLICKGERTDDVSGIILDESLLRAYSVPGAGGHSRVQDSLGPVLRE
:::::
CCDS44 FGSDKGVFSFEAGRRCHSGEGLFAFSTPCAPDLCRAVAGAIARQRERLPELTRPQPCPLP
270 280 290 300 310 320
>>CCDS47349.1 DOK3 gene_id:79930|Hs108|chr5 (228 aa)
initn: 1219 init1: 1080 opt: 1364 Z-score: 1583.4 bits: 300.8 E(32554): 7.1e-82
Smith-Waterman score: 1364; 99.0% identity (99.0% similar) in 206 aa overlap (125-329:23-228)
100 110 120 130 140 150
pF1KE0 FLLTTTERSHLLAAQHRQAWMGPICQLAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSS
::::::::::::::::::::::::::::::
CCDS47 MDPLETPIKDGILYQQHVKFGKGTGEASSGSTDAQSPKRGLVPMEENSIYSS
10 20 30 40 50
160 170 180 190 200 210
pF1KE0 WQEVGEFPVVVQRTEAATRCQLKGPALLVLGPDAIQLREAKGTQALYSWPYHFLRKFGSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 WQEVGEFPVVVQRTEAATRCQLKGPALLVLGPDAIQLREAKGTQALYSWPYHFLRKFGSD
60 70 80 90 100 110
220 230 240 250 260 270
pF1KE0 KILLGTPGVSLLICKGERTDDVSGIILDESLLRAYSVPGAGGHSRVQDSLGPVLREPTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 KILLGTPGVSLLICKGERTDDVSGIILDESLLRAYSVPGAGGHSRVQDSLGPVLREPTFQ
120 130 140 150 160 170
280 290 300 310 320
pF1KE0 GERSFLKTSMLRSL-CSCSWRHPRSQPCTQASCLQGSDCPAPHRNSTSAAHTLGTS
:::::::::::::: :::::::::::: ::::::::::::::::::::::::::::
CCDS47 GERSFLKTSMLRSLLCSCSWRHPRSQPRTQASCLQGSDCPAPHRNSTSAAHTLGTS
180 190 200 210 220
>>CCDS1954.1 DOK1 gene_id:1796|Hs108|chr2 (481 aa)
initn: 410 init1: 147 opt: 504 Z-score: 583.6 bits: 116.8 E(32554): 3.5e-26
Smith-Waterman score: 504; 35.9% identity (61.3% similar) in 287 aa overlap (4-276:1-273)
10 20 30 40 50 60
pF1KE0 MDPLETPIKDGILYQQHVKFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRS
.. . .: :. : .:: : :::.::.:: ..: :::::: .. . : ...: :
CCDS19 MDGAVMEGPLFLQSQRFGTKRWRKTWAVLYPASPHGVARLEFFDHK--GSSSGGGR-
10 20 30 40 50
70 80 90 100 110
pF1KE0 AGPGRRGERRVIRLADCVSVLPADGESCPRDTG-AFLLTTTERSHLLAAQ--HRQAWMGP
: .:: . .:::::.:::: :. :. :. . :: : :..:::::::. ::.
CCDS19 -GSSRRLDCKVIRLAECVSVAPVTVETPPEPGATAFRLDTAQRSHLLAADAPSSAAWVQT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 ICQLAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLK
.:. ::: : . . :: . :: . . : :::.:: : ..: :.::::::: :: :.
CCDS19 LCRNAFP-KGSWTLAPTD-NPPKLSALEMLENSLYSPTWEGSQFWVTVQRTEAAERCGLH
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 GPALLVLGPDAIQL----REAKGTQALYSWPYHFLRKFGSDKILLG------TP-GVSLL
: .: . . . : ... . : :::: .::..: ::.... : : . .
CCDS19 GSYVLRVEAERLTLLTVGAQSQILEPLLSWPYTLLRRYGRDKVMFSFEAGRRCPSGPGTF
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 ICKGERTDDVSGIILDESLLRAYSVPGAGGHSRVQDSLGPVLREPTFQGERSFLKTSMLR
. . .:. . :. .. .. : .:... ::: . .::
CCDS19 TFQTAQGNDIFQAV--ETAIHRQKAQGKAGQGH------DVLRADSHEGEVAEGKLPSPP
240 250 260 270 280
290 300 310 320
pF1KE0 SLCSCSWRHPRSQPCTQASCLQGSDCPAPHRNSTSAAHTLGTS
CCDS19 GPQELLDSPPALYAEPLDSLRIAPCPSQDSLYSDPLDSTSAQAGEGVQRKKPLYWDLYEH
290 300 310 320 330 340
>>CCDS6016.1 DOK2 gene_id:9046|Hs108|chr8 (412 aa)
initn: 422 init1: 102 opt: 485 Z-score: 562.6 bits: 112.7 E(32554): 5.1e-25
Smith-Waterman score: 485; 46.3% identity (61.9% similar) in 218 aa overlap (8-216:6-207)
10 20 30 40 50
pF1KE0 MDPLETPIKDGILY-QQHVKFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDR
.:.:.:: ::. :::: ::. : ::.:. ..:::: : : :
CCDS60 MGDGAVKQGFLYLQQQQTFGKK-WRRFGASLYGGSDCALARLELQE------GPEKPR
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 SAGPGRRGERRVIRLADCVSVLPADGE-SCPRDTGAFLLTTTERSHLLAAQ--HRQAWMG
.. :.::::.::. : : :: : ::::.::.: : :: .:::: .: :.
CCDS60 RC----EAARKVIRLSDCLRVAEAGGEASSPRDTSAFFLETKERLYLLAAPAAERGDWVQ
60 70 80 90 100
120 130 140 150 160 170
pF1KE0 PICQLAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVG---EFPVVVQRTEAATR
:: ::::: . :: :: : :::: .::: :: :: :... :::. :
CCDS60 AICLLAFPGQRKELSGPEGKQS--RPC--MEENELYSSAVTVGPHKEFAVTMRPTEASER
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE0 CQLKGPALLVLGPDAIQLR--EAKGTQALYSWPYHFLRKFGSDKILLGTPGVSLLICKGE
:.:.: : : .:..: ::: ::.:::.:::.:: ::.
CCDS60 CHLRGSYTLRAGESALELWGGPEPGTQ-LYDWPYRFLRRFGRDKVTFSFEAGRRCVSGEG
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE0 RTDDVSGIILDESLLRAYSVPGAGGHSRVQDSLGPVLREPTFQGERSFLKTSMLRSLCSC
CCDS60 NFEFETRQGNEIFLALEEAISAQKNAAPATPQPQPATIPASLPRPDSPYSRPHDSLPPPS
230 240 250 260 270 280
>>CCDS82474.1 DOK1 gene_id:1796|Hs108|chr2 (177 aa)
initn: 258 init1: 147 opt: 358 Z-score: 420.8 bits: 85.3 E(32554): 4.1e-17
Smith-Waterman score: 358; 42.7% identity (66.9% similar) in 157 aa overlap (4-156:1-151)
10 20 30 40 50 60
pF1KE0 MDPLETPIKDGILYQQHVKFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRS
.. . .: :. : .:: : :::.::.:: ..: :::::: .. . : ...: :
CCDS82 MDGAVMEGPLFLQSQRFGTKRWRKTWAVLYPASPHGVARLEFFDHK--GSSSGGGR-
10 20 30 40 50
70 80 90 100 110
pF1KE0 AGPGRRGERRVIRLADCVSVLPADGESCPRDTG-AFLLTTTERSHLLAAQ--HRQAWMGP
: .:: . .:::::.:::: :. :. :. . :: : :..:::::::. ::.
CCDS82 -GSSRRLDCKVIRLAECVSVAPVTVETPPEPGATAFRLDTAQRSHLLAADAPSSAAWVQT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 ICQLAFPGTGEASSGSTDAQSPKRGLVPMEENSIYS-SWQEVGEFPVVVQRTEAATRCQL
.:. ::: : . . :: . :: . . : :::.:: .:.
CCDS82 LCRNAFP-KGSWTLAPTD-NPPKLSALEMLENSLYSPTWEGHVLFRGRPPLPLRPWNLHL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 KGPALLVLGPDAIQLREAKGTQALYSWPYHFLRKFGSDKILLGTPGVSLLICKGERTDDV
CCDS82 PDGTGK
329 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:35:02 2016 done: Sat Nov 5 18:35:03 2016
Total Scan time: 2.890 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]