Result of FASTA (ccds) for
pFN21AB0409
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0409, 466 aa
1>>>pF1KB0409 466 - 466 aa - 466 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8712+/-0.00111; mu= 15.5412+/- 0.065
mean_var=159.6661+/-30.114, 0's: 0 Z-trim(108.9): 235 B-trim: 13 in 2/49
Lambda= 0.101500
statistics sampled from 10204 (10489) to 10204 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.322), width: 16
Scan time: 3.030
The best scores are: opt bits E(32554)
CCDS9528.1 F7 gene_id:2155|Hs108|chr13 ( 466) 3294 495.0 7e-140
CCDS9529.1 F7 gene_id:2155|Hs108|chr13 ( 444) 2992 450.7 1.4e-126
CCDS73602.1 F7 gene_id:2155|Hs108|chr13 ( 382) 2578 390.0 2.3e-108
CCDS83495.1 F9 gene_id:2158|Hs108|chrX ( 423) 689 113.5 4.5e-25
CCDS2145.1 PROC gene_id:5624|Hs108|chr2 ( 461) 687 113.2 5.7e-25
CCDS81783.1 F10 gene_id:2159|Hs108|chr13 ( 332) 618 102.9 5.2e-22
CCDS74856.1 TMPRSS6 gene_id:164656|Hs108|chr22 ( 802) 621 103.9 6.5e-22
CCDS13941.1 TMPRSS6 gene_id:164656|Hs108|chr22 ( 811) 621 103.9 6.5e-22
CCDS9530.1 F10 gene_id:2159|Hs108|chr13 ( 488) 618 103.2 6.5e-22
CCDS34120.1 KLKB1 gene_id:3818|Hs108|chr4 ( 638) 600 100.7 4.8e-21
CCDS45469.1 PRSS8 gene_id:5652|Hs108|chr16 ( 343) 594 99.4 6.1e-21
CCDS14666.1 F9 gene_id:2158|Hs108|chrX ( 461) 592 99.3 8.8e-21
CCDS3847.1 F11 gene_id:2160|Hs108|chr4 ( 625) 590 99.2 1.3e-20
CCDS13571.1 TMPRSS15 gene_id:5651|Hs108|chr21 (1019) 567 96.1 1.8e-19
CCDS8487.1 ST14 gene_id:6768|Hs108|chr11 ( 855) 557 94.6 4.5e-19
CCDS12088.1 TMPRSS9 gene_id:360200|Hs108|chr19 (1059) 553 94.1 7.6e-19
CCDS33564.1 TMPRSS2 gene_id:7113|Hs108|chr21 ( 492) 547 92.8 8.9e-19
CCDS10481.1 PRSS22 gene_id:64063|Hs108|chr16 ( 317) 544 92.1 9.2e-19
CCDS54486.1 TMPRSS2 gene_id:7113|Hs108|chr21 ( 529) 547 92.8 9.2e-19
CCDS58452.1 PRSS36 gene_id:146547|Hs108|chr16 ( 752) 541 92.1 2.1e-18
CCDS58453.1 PRSS36 gene_id:146547|Hs108|chr16 ( 850) 541 92.2 2.3e-18
CCDS32436.1 PRSS36 gene_id:146547|Hs108|chr16 ( 855) 541 92.2 2.3e-18
CCDS10476.1 PRSS27 gene_id:83886|Hs108|chr16 ( 290) 532 90.3 3e-18
CCDS32993.1 HPN gene_id:3249|Hs108|chr19 ( 417) 529 90.0 5e-18
CCDS55788.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 532) 530 90.3 5.2e-18
CCDS41721.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 567) 530 90.4 5.4e-18
CCDS58790.1 TMPRSS3 gene_id:64699|Hs108|chr21 ( 453) 528 89.9 5.8e-18
CCDS42110.1 PRSS33 gene_id:260429|Hs108|chr16 ( 280) 521 88.6 8.9e-18
CCDS3369.1 HGFAC gene_id:3083|Hs108|chr4 ( 655) 525 89.7 9.8e-18
CCDS13686.1 TMPRSS3 gene_id:64699|Hs108|chr21 ( 454) 519 88.6 1.4e-17
CCDS58185.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 563) 520 88.9 1.5e-17
CCDS43129.2 TMPRSS7 gene_id:344805|Hs108|chr3 ( 717) 519 88.9 1.9e-17
CCDS3709.1 PRSS12 gene_id:8492|Hs108|chr4 ( 875) 519 89.0 2.1e-17
CCDS75098.1 HGFAC gene_id:3083|Hs108|chr4 ( 662) 515 88.3 2.7e-17
CCDS73251.1 OVCH2 gene_id:341277|Hs108|chr11 ( 565) 512 87.7 3.4e-17
CCDS10431.1 TPSAB1 gene_id:7177|Hs108|chr16 ( 275) 497 85.1 1e-16
CCDS1563.1 PRSS38 gene_id:339501|Hs108|chr1 ( 326) 495 84.9 1.4e-16
CCDS10430.1 TPSG1 gene_id:25823|Hs108|chr16 ( 321) 494 84.8 1.5e-16
CCDS73391.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 413) 488 84.0 3.2e-16
CCDS73392.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 448) 488 84.1 3.3e-16
CCDS44735.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 457) 488 84.1 3.4e-16
CCDS10478.1 PRSS21 gene_id:10942|Hs108|chr16 ( 314) 485 83.4 3.7e-16
CCDS123.1 MASP2 gene_id:10747|Hs108|chr1 ( 686) 488 84.3 4.3e-16
CCDS53579.1 HABP2 gene_id:3026|Hs108|chr10 ( 534) 483 83.4 6.2e-16
CCDS7577.1 HABP2 gene_id:3026|Hs108|chr10 ( 560) 483 83.5 6.3e-16
CCDS47145.1 PRSS48 gene_id:345062|Hs108|chr4 ( 328) 475 82.0 1e-15
CCDS44881.1 TMPRSS12 gene_id:283471|Hs108|chr12 ( 348) 457 79.4 6.7e-15
CCDS44442.1 PLAU gene_id:5328|Hs108|chr10 ( 414) 452 78.8 1.2e-14
CCDS7339.1 PLAU gene_id:5328|Hs108|chr10 ( 431) 452 78.8 1.3e-14
CCDS14101.1 ACR gene_id:49|Hs108|chr22 ( 421) 448 78.2 1.9e-14
>>CCDS9528.1 F7 gene_id:2155|Hs108|chr13 (466 aa)
initn: 3294 init1: 3294 opt: 3294 Z-score: 2624.8 bits: 495.0 E(32554): 7e-140
Smith-Waterman score: 3294; 100.0% identity (100.0% similar) in 466 aa overlap (1-466:1-466)
10 20 30 40 50 60
pF1KB0 MVSQALRLLCLLLGLQGCLAAGGVAKASGGETRDMPWKPGPHRVFVTQEEAHGVLHRRRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 MVSQALRLLCLLLGLQGCLAAGGVAKASGGETRDMPWKPGPHRVFVTQEEAHGVLHRRRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 ANAFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 ANAFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 CKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 CKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 LADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 LADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 TLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 TLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 HDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 HDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 NVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 NVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTG
370 380 390 400 410 420
430 440 450 460
pF1KB0 IVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP
::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 IVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP
430 440 450 460
>>CCDS9529.1 F7 gene_id:2155|Hs108|chr13 (444 aa)
initn: 3113 init1: 2992 opt: 2992 Z-score: 2386.1 bits: 450.7 E(32554): 1.4e-126
Smith-Waterman score: 3073; 95.3% identity (95.3% similar) in 466 aa overlap (1-466:1-444)
10 20 30 40 50 60
pF1KB0 MVSQALRLLCLLLGLQGCLAAGGVAKASGGETRDMPWKPGPHRVFVTQEEAHGVLHRRRR
::::::::::::::::::::: :::::::::::::::::
CCDS95 MVSQALRLLCLLLGLQGCLAA----------------------VFVTQEEAHGVLHRRRR
10 20 30
70 80 90 100 110 120
pF1KB0 ANAFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 ANAFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB0 CKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 CKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB0 LADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 LADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB0 TLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 TLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTN
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB0 HDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 HDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVL
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB0 NVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 NVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTG
340 350 360 370 380 390
430 440 450 460
pF1KB0 IVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP
::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 IVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP
400 410 420 430 440
>>CCDS73602.1 F7 gene_id:2155|Hs108|chr13 (382 aa)
initn: 2578 init1: 2578 opt: 2578 Z-score: 2059.1 bits: 390.0 E(32554): 2.3e-108
Smith-Waterman score: 2578; 99.7% identity (100.0% similar) in 362 aa overlap (105-466:21-382)
80 90 100 110 120 130
pF1KB0 RECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLP
.:::::::::::::::::::::::::::::
CCDS73 MVSQALRLLCLLLGLQGCLAADGDQCASSPCQNGGSCKDQLQSYICFCLP
10 20 30 40 50
140 150 160 170 180 190
pF1KB0 AFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 AFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYP
60 70 80 90 100 110
200 210 220 230 240 250
pF1KB0 CGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 CGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHC
120 130 140 150 160 170
260 270 280 290 300 310
pF1KB0 FDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 FDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVL
180 190 200 210 220 230
320 330 340 350 360 370
pF1KB0 TDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCLQQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 TDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCLQQS
240 250 260 270 280 290
380 390 400 410 420 430
pF1KB0 RKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 RKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHF
300 310 320 330 340 350
440 450 460
pF1KB0 GVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP
::::::::::::::::::::::::::::::::
CCDS73 GVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP
360 370 380
>>CCDS83495.1 F9 gene_id:2158|Hs108|chrX (423 aa)
initn: 1021 init1: 310 opt: 689 Z-score: 563.7 bits: 113.5 E(32554): 4.5e-25
Smith-Waterman score: 932; 36.0% identity (60.1% similar) in 444 aa overlap (44-449:30-418)
20 30 40 50 60 70
pF1KB0 GLQGCLAAGGVAKASGGETRDMPWKPGPHRVFVTQEEAHGVLHRRRRANAF-LEELRPGS
::. .:.:. .:.: .: :. :::. :.
CCDS83 MQRVNMIMAESPGLITICLLGYLLSAECTVFLDHENANKILNRPKRYNSGKLEEFVQGN
10 20 30 40 50
80 90 100 110 120 130
pF1KB0 LERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFC
::::: ::.::::::::.:...::: :: .: :
CCDS83 LERECMEEKCSFEEAREVFENTERTTEFWKQYVD--------------------------
60 70 80 90
140 150 160 170 180 190
pF1KB0 LPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVE
. : .:: :::.:.. . .: : : ::: : . :: :.:
CCDS83 ----------------VTCNIKNGRCEQFCKNSADNKVVCSCTEGYRLAENQKSCEPAVP
100 110 120 130
200 210 220
pF1KB0 YPCGKI---------------PILEKRNASKPQG----------------RIVGGKVCPK
.:::.. : .. :... . :.:::.
CCDS83 FPCGRVSVSQTSKLTRAETVFPDVDYVNSTEAETILDNITQSTQSFNDFTRVVGGEDAKP
140 150 160 170 180 190
230 240 250 260 270
pF1KB0 GECPWQVLLLVNGA--QLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGD
:. ::::.: :: .:::...: :.:.:::: ... .. .: :::.. : .
CCDS83 GQFPWQVVL--NGKVDAFCGGSIVNEKWIVTAAHC---VETGVKITVVAGEHNIEETEHT
200 210 220 230 240 250
280 290 300 310 320 330
pF1KB0 EQSRRVAQVIIPSTYVPGTT--NHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVR
::.: : ..: .: . . :::::::.: .:.::...:.:.:. .. : : :..
CCDS83 EQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADK---EYTNIFLK
260 270 280 290 300
340 350 360 370 380 390
pF1KB0 FS--LVSGWGQLLDRGATALELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDG
:. :::::... .: .:: :. : :: . ::.... . : . :::::. .:
CCDS83 FGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFT-----IYNNMFCAGFHEG
310 320 330 340 350 360
400 410 420 430 440 450
pF1KB0 SKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEP
..:::.:::::::.:. .:: .::::.:::. :: :..:.::.::.:..:...
CCDS83 GRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT
370 380 390 400 410 420
460
pF1KB0 RPGVLLRAPFP
>>CCDS2145.1 PROC gene_id:5624|Hs108|chr2 (461 aa)
initn: 920 init1: 290 opt: 687 Z-score: 561.7 bits: 113.2 E(32554): 5.7e-25
Smith-Waterman score: 1110; 40.0% identity (67.6% similar) in 447 aa overlap (39-457:20-455)
10 20 30 40 50 60
pF1KB0 LCLLLGLQGCLAAGGVAKASGGETRDMPWKPGP-HRVFVTQEEAHGVLHRRRRANAFLEE
:.: :: ..:.:: ::. :.:::.::::
CCDS21 MWQLTSLLLFVATWGISGTPAPLDSVFSSSERAHQVLRIRKRANSFLEE
10 20 30 40
70 80 90 100 110
pF1KB0 LRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSP--------CQNGG
:: .:::::: :: :.::::.:::.... : :: .. ::::: : : . :
CCDS21 LRHSSLERECIEEICDFEEAKEIFQNVDDTLAFWSKHVDGDQCLVLPLEHPCASLCCGHG
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB0 SCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYS
.: : . :. : : ..::: :. .. . : : .:::: .:: ...: .: : : ::.
CCDS21 TCIDGIGSFSCDCRSGWEGRFCQ-REVSFLNCSLDNGGCTHYCLEEVGWRR-CSCAPGYK
110 120 130 140 150 160
180 190 200 210 220
pF1KB0 LLADGVSCTPTVEYPCGKIPI--LEKRNA-----SKPQ-----GRIVGGKVCPKGECPWQ
: : ..: :.:..:::. : .::. . .. : :.. ::. .:. :::
CCDS21 LGDDLLQCHPAVKFPCGR-PWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQ
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB0 VLLLVNGAQL-CGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVA
:.:: . .: ::..::. ::..::::.:. :. :.. :::.:: . . : . .
CCDS21 VVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKK---LLVRLGEYDLRRWEKWELDLDIK
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB0 QVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFV-RFSLVSGWG
.:.. .: .::..:::::.: ::..:.. .::.:::. ..:: : . . .::.:::
CCDS21 EVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWG
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB0 QLLDRGATALE--LMVLN---VPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSC
.: : . .::: .: . ..: . : ..: :.::: .:.:
CCDS21 YHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVM-----SNMVSENMLCAGILGDRQDAC
350 360 370 380 390
410 420 430 440 450 460
pF1KB0 KGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVL
.:::::: .. ..:::.:.:.::::.::. . ..::::.::.:..:.. .:.. :
CCDS21 EGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGHIRDKEAPQKS
400 410 420 430 440 450
pF1KB0 LRAPFP
CCDS21 WAP
460
>>CCDS81783.1 F10 gene_id:2159|Hs108|chr13 (332 aa)
initn: 732 init1: 455 opt: 618 Z-score: 508.6 bits: 102.9 E(32554): 5.2e-22
Smith-Waterman score: 703; 40.2% identity (62.0% similar) in 266 aa overlap (44-262:24-285)
20 30 40 50 60 70
pF1KB0 GLQGCLAAGGVAKASGGETRDMPWKPGPHRVFVTQEEAHGVLHRRRRANAFLEELRPGSL
.:. .:.:...: : :::.::::.. : :
CCDS81 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHL
10 20 30 40 50
80 90 100 110 120 130
pF1KB0 ERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCL
:::: :: ::.:::::.:.:...:. :: .:.::::: .::::: :.::: : : : ::
CCDS81 ERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCL
60 70 80 90 100 110
140 150 160 170 180 190
pF1KB0 PAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEY
.:::.::: . .: .:: :.:.: .. .. : : .::.: .: .: :: :
CCDS81 EGFEGKNCELFT--RKLCSLDNGDCDQFCHEEQNSV-VCSCARGYTLADNGKACIPTGPY
120 130 140 150 160 170
200 210
pF1KB0 PCGKIPILEKR----------------------------------------NASKPQ-G-
:::: ::.: : ..:. :
CCDS81 PCGK-QTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGD
180 190 200 210 220
220 230 240 250 260
pF1KB0 ----RIVGGKVCPKGECPWQVLLLVNGAQ-LCGGTLINTIWVVSAAHCFDKIKNWRNLIA
:::::. : ::::::.::. . . .::::... .....::::. . : ..
CCDS81 NNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKGTGT
230 240 250 260 270 280
270 280 290 300 310 320
pF1KB0 VLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPER
CCDS81 RSRRRAVRRCTRWRWSSSTTGSQRRPMTSTSPCSGSRPPSPSA
290 300 310 320 330
>>CCDS74856.1 TMPRSS6 gene_id:164656|Hs108|chr22 (802 aa)
initn: 502 init1: 201 opt: 621 Z-score: 506.9 bits: 103.9 E(32554): 6.5e-22
Smith-Waterman score: 630; 32.9% identity (58.0% similar) in 362 aa overlap (110-451:461-801)
80 90 100 110 120 130
pF1KB0 EQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGR
:. . :.. .: . :. : : .:.
CCDS74 LTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPA-CDGVKDCPNGLDERNCVCRATFQ--
440 450 460 470 480
140 150 160 170 180 190
pF1KB0 NCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEG-----YSLLADGVSCTPTVEYP
: :.:. :.. :. . .:. . .:.:: ... . ::. .
CCDS74 -C---KEDST-CISLPKVCDGQPDCLNGSDEE-QCQEGVPCGTFTFQCEDRSCVKKPNPQ
490 500 510 520 530 540
200 210 220 230 240
pF1KB0 CGKIPILEKRNASK----------PQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLIN
: : . :..: :..::::: : .:: :::. : : : ..:::.::
CCDS74 CDGRP--DCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIA
550 560 570 580 590
250 260 270 280 290 300
pF1KB0 TIWVVSAAHCF--DKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHD
::..::::: :.. . . ::. . . : : .:..... . . ..:
CCDS74 DRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYD
600 610 620 630 640 650
310 320 330 340 350 360
pF1KB0 IALLRLHQPVVLTDHVVPLCLPERT-FSERTLAFVRFSLVSGWGQLLDRGATALELMVLN
.:::.: .::: . : :.::: :. : : : ..::: : . : . :. ..
CCDS74 VALLQLDHPVVRSAAVRPVCLPARSHFFEPGL----HCWITGWGALREGGPISNALQKVD
660 670 680 690 700 710
370 380 390 400 410
pF1KB0 VPRLMTQD-CLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATH-YRGTWYLT
: .:. :: : . : ..: :.:::: :.::.:.:::::: . . : :.:.
CCDS74 V-QLIPQDLCSEVYRY-----QVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLA
720 730 740 750 760
420 430 440 450 460
pF1KB0 GIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP
:.:::: ::. ..::::::.. : :.:...
CCDS74 GLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
770 780 790 800
>>CCDS13941.1 TMPRSS6 gene_id:164656|Hs108|chr22 (811 aa)
initn: 502 init1: 201 opt: 621 Z-score: 506.9 bits: 103.9 E(32554): 6.5e-22
Smith-Waterman score: 630; 32.9% identity (58.0% similar) in 362 aa overlap (110-451:470-810)
80 90 100 110 120 130
pF1KB0 EQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGR
:. . :.. .: . :. : : .:.
CCDS13 LTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPA-CDGVKDCPNGLDERNCVCRATFQ--
440 450 460 470 480 490
140 150 160 170 180 190
pF1KB0 NCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEG-----YSLLADGVSCTPTVEYP
: :.:. :.. :. . .:. . .:.:: ... . ::. .
CCDS13 -C---KEDST-CISLPKVCDGQPDCLNGSDEE-QCQEGVPCGTFTFQCEDRSCVKKPNPQ
500 510 520 530 540 550
200 210 220 230 240
pF1KB0 CGKIPILEKRNASK----------PQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLIN
: : . :..: :..::::: : .:: :::. : : : ..:::.::
CCDS13 CDGRP--DCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIA
560 570 580 590 600
250 260 270 280 290 300
pF1KB0 TIWVVSAAHCF--DKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHD
::..::::: :.. . . ::. . . : : .:..... . . ..:
CCDS13 DRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYD
610 620 630 640 650 660
310 320 330 340 350 360
pF1KB0 IALLRLHQPVVLTDHVVPLCLPERT-FSERTLAFVRFSLVSGWGQLLDRGATALELMVLN
.:::.: .::: . : :.::: :. : : : ..::: : . : . :. ..
CCDS13 VALLQLDHPVVRSAAVRPVCLPARSHFFEPGL----HCWITGWGALREGGPISNALQKVD
670 680 690 700 710 720
370 380 390 400 410
pF1KB0 VPRLMTQD-CLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATH-YRGTWYLT
: .:. :: : . : ..: :.:::: :.::.:.:::::: . . : :.:.
CCDS13 V-QLIPQDLCSEVYRY-----QVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLA
730 740 750 760 770
420 430 440 450 460
pF1KB0 GIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP
:.:::: ::. ..::::::.. : :.:...
CCDS13 GLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
780 790 800 810
>>CCDS9530.1 F10 gene_id:2159|Hs108|chr13 (488 aa)
initn: 1248 init1: 455 opt: 618 Z-score: 506.9 bits: 103.2 E(32554): 6.5e-22
Smith-Waterman score: 1206; 39.0% identity (66.2% similar) in 461 aa overlap (44-457:24-472)
20 30 40 50 60 70
pF1KB0 GLQGCLAAGGVAKASGGETRDMPWKPGPHRVFVTQEEAHGVLHRRRRANAFLEELRPGSL
.:. .:.:...: : :::.::::.. : :
CCDS95 MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHL
10 20 30 40 50
80 90 100 110 120 130
pF1KB0 ERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCL
:::: :: ::.:::::.:.:...:. :: .:.::::: .::::: :.::: : : : ::
CCDS95 ERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCL
60 70 80 90 100 110
140 150 160 170 180 190
pF1KB0 PAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEY
.:::.::: . .: .:: :.:.: .. .. : : .::.: .: .: :: :
CCDS95 EGFEGKNCELF--TRKLCSLDNGDCDQFCHEEQNSV-VCSCARGYTLADNGKACIPTGPY
120 130 140 150 160 170
200 210
pF1KB0 PCGKIPILEKR----------------------------------------NASKPQ-G-
:::: ::.: : ..:. :
CCDS95 PCGK-QTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGD
180 190 200 210 220
220 230 240 250 260
pF1KB0 ----RIVGGKVCPKGECPWQVLLLVNGAQ-LCGGTLINTIWVVSAAHCFDKIKNWRNLIA
:::::. : ::::::.::. . . .::::... .....::::. . : .. .
CCDS95 NNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRV-
230 240 250 260 270 280
270 280 290 300 310 320
pF1KB0 VLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPER
:... ...: : ..: :: . .. : . :::.:::. :... .:.: :::::
CCDS95 --GDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPER
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB0 TFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCLQQSRKVGDSPNITEY
..: :: . ..:::.:. ..: . .: .:.:: . ..: :...: ::.
CCDS95 DWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSC-----KLSSSFIITQN
350 360 370 380 390 400
390 400 410 420 430 440
pF1KB0 MFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEW
::::::. ..:.:.:::::::.:... :...:::::::.::: :..:.::.:. ...:
CCDS95 MFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKW
410 420 430 440 450 460
450 460
pF1KB0 LQKLMRSEPRPGVLLRAPFP
... :... :
CCDS95 IDRSMKTRGLPKAKSHAPEVITSSPLK
470 480
>>CCDS34120.1 KLKB1 gene_id:3818|Hs108|chr4 (638 aa)
initn: 591 init1: 290 opt: 600 Z-score: 491.4 bits: 100.7 E(32554): 4.8e-21
Smith-Waterman score: 611; 38.9% identity (65.4% similar) in 257 aa overlap (207-456:385-631)
180 190 200 210 220 230
pF1KB0 GYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVN-GA
.: . ::::: :: :::: : :. :
CCDS34 GSPTRIAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTA
360 370 380 390 400 410
240 250 260 270 280 290
pF1KB0 Q--LCGGTLINTIWVVSAAHCFDKIK---NWRNLIAVLGEHDLSEHDGDEQSRRVAQVII
: ::::.::. ::..:::::: . :: ..:. :... : .. ..::
CCDS34 QRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITK---DTPFSQIKEIII
420 430 440 450 460 470
300 310 320 330 340 350
pF1KB0 PSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDR
..: . ::::::..:. :. :. :.::: . .. . .. :.::: ..
CCDS34 HQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK--GDTSTIYTN-CWVTGWGFSKEK
480 490 500 510 520
360 370 380 390 400 410
pF1KB0 GATALELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHAT
: :. .:.: . ...: ... : .::. : ::::..:.::.:::::::: .
CCDS34 GEIQNILQKVNIPLVTNEEC---QKRYQDY-KITQRMVCAGYKEGGKDACKGDSGGPLVC
530 540 550 560 570 580
420 430 440 450 460
pF1KB0 HYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEW-LQKLMRSEPRPGVLLRAPFP
.. : : :.::.:::.::: . ::::.:..:..: :.: . :. .
CCDS34 KHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSPA
590 600 610 620 630
466 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:02:38 2016 done: Sat Nov 5 18:02:38 2016
Total Scan time: 3.030 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]