Result of FASTA (omim) for
pFN21AB0973
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0973, 210 aa
1>>>pF1KB0973 210 - 210 aa - 210 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0199+/-0.000357; mu= 14.8815+/- 0.022
mean_var=61.4201+/-12.569, 0's: 0 Z-trim(113.3): 41 B-trim: 101 in 1/48
Lambda= 0.163651
statistics sampled from 22519 (22559) to 22519 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.265), width: 16
Scan time: 5.570
The best scores are: opt bits E(85289)
NP_000843 (OMIM: 134660) glutathione S-transferase ( 210) 1403 339.6 2.3e-93
NP_000840 (OMIM: 138390) glutathione S-transferase ( 225) 383 98.8 7.4e-21
NP_000839 (OMIM: 138380) glutathione S-transferase ( 218) 357 92.6 5.1e-19
NP_000841 (OMIM: 138333) glutathione S-transferase ( 218) 345 89.8 3.6e-18
NP_000842 (OMIM: 138385) glutathione S-transferase ( 218) 329 86.0 5e-17
XP_005270841 (OMIM: 138385) PREDICTED: glutathione ( 218) 329 86.0 5e-17
NP_000552 (OMIM: 138350) glutathione S-transferase ( 218) 327 85.5 6.9e-17
NP_001135840 (OMIM: 138380) glutathione S-transfer ( 191) 325 85.0 8.6e-17
NP_671489 (OMIM: 138333) glutathione S-transferase ( 195) 315 82.7 4.5e-16
XP_016856574 (OMIM: 138333) PREDICTED: glutathione ( 254) 315 82.7 5.6e-16
XP_016856576 (OMIM: 138333) PREDICTED: glutathione ( 177) 308 81.0 1.3e-15
NP_000838 (OMIM: 605449) glutathione S-transferase ( 222) 296 78.2 1.1e-14
NP_665683 (OMIM: 138359) glutathione S-transferase ( 222) 293 77.5 1.8e-14
XP_005270839 (OMIM: 138350) PREDICTED: glutathione ( 184) 290 76.8 2.6e-14
XP_011512834 (OMIM: 138360) PREDICTED: glutathione ( 222) 289 76.6 3.5e-14
NP_000837 (OMIM: 138360) glutathione S-transferase ( 222) 289 76.6 3.5e-14
NP_714543 (OMIM: 607605) glutathione S-transferase ( 222) 279 74.2 1.8e-13
XP_016856575 (OMIM: 138333) PREDICTED: glutathione ( 213) 278 74.0 2.1e-13
XP_005249092 (OMIM: 605450) PREDICTED: glutathione ( 222) 277 73.7 2.5e-13
NP_001503 (OMIM: 605450) glutathione S-transferase ( 222) 277 73.7 2.5e-13
XP_005249091 (OMIM: 138359) PREDICTED: glutathione ( 225) 255 68.6 9.3e-12
XP_016866283 (OMIM: 605449) PREDICTED: glutathione ( 172) 247 66.6 2.8e-11
XP_006715135 (OMIM: 605449) PREDICTED: glutathione ( 172) 247 66.6 2.8e-11
XP_011512836 (OMIM: 605450) PREDICTED: glutathione ( 185) 245 66.1 4.1e-11
XP_011512837 (OMIM: 605450) PREDICTED: glutathione ( 185) 245 66.1 4.1e-11
NP_055300 (OMIM: 602598) hematopoietic prostagland ( 199) 228 62.1 7e-10
XP_016856577 (OMIM: 138333) PREDICTED: glutathione ( 150) 189 52.9 3.3e-07
XP_005270842 (OMIM: 138385) PREDICTED: glutathione ( 114) 181 50.9 9.7e-07
NP_666533 (OMIM: 138350) glutathione S-transferase ( 181) 174 49.4 4.5e-06
XP_011512835 (OMIM: 605449) PREDICTED: glutathione ( 129) 147 42.9 0.00028
NP_001305988 (OMIM: 138359) glutathione S-transfer ( 129) 146 42.7 0.00033
>>NP_000843 (OMIM: 134660) glutathione S-transferase P [ (210 aa)
initn: 1403 init1: 1403 opt: 1403 Z-score: 1797.3 bits: 339.6 E(85289): 2.3e-93
Smith-Waterman score: 1403; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:1-210)
10 20 30 40 50 60
pF1KB0 MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 LTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 KALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAY
130 140 150 160 170 180
190 200 210
pF1KB0 VGRLSARPKLKAFLASPEYVNLPINGNGKQ
::::::::::::::::::::::::::::::
NP_000 VGRLSARPKLKAFLASPEYVNLPINGNGKQ
190 200 210
>>NP_000840 (OMIM: 138390) glutathione S-transferase Mu (225 aa)
initn: 312 init1: 136 opt: 383 Z-score: 495.4 bits: 98.8 E(85289): 7.4e-21
Smith-Waterman score: 383; 32.1% identity (62.3% similar) in 212 aa overlap (8-210:11-218)
10 20 30 40
pF1KB0 MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTV--------ETWQEGSLKASCL
:. .:: :.:.:: :..:. : : . ..: .
NP_000 MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB0 YGQLPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIY
. .:: . :: . :::.:::...: .. :. ..: ::.... : :.: . : : :
NP_000 FPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB0 T-NYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAP
. ..: : .:.. :::::: : .: : ....:....:.:. :.: .... :
NP_000 SSDHEKLKPQYLEELPGQLKQFSMFL----GKFSWFAGEKLTFVDFLTYDILDQNRIFDP
130 140 150 160 170
170 180 190 200 210
pF1KB0 GCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ
::: :: :.:.. :. : :. :.: : .. ..:::.. :
NP_000 KCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC
180 190 200 210 220
>>NP_000839 (OMIM: 138380) glutathione S-transferase Mu (218 aa)
initn: 313 init1: 143 opt: 357 Z-score: 462.4 bits: 92.6 E(85289): 5.1e-19
Smith-Waterman score: 357; 30.8% identity (63.0% similar) in 211 aa overlap (3-204:2-208)
10 20 30 40 50
pF1KB0 MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTV--------ETWQEGSLKASCLYGQ
:.:. :. .:: ..:.:: .:..:. :. : . ..: . . .
NP_000 MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN
10 20 30 40 50
60 70 80 90 100 110
pF1KB0 LPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYT-N
:: . :: . :::.:::...: .: :....: :.... : : . .: : .
NP_000 LPYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB0 YEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCL
.: : .:..::: .:: : :: : . ...::.:.:.:. :.: ..:. :.::
NP_000 FEKLKPEYLQALPEMLK----LYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCL
120 130 140 150 160 170
180 190 200 210
pF1KB0 DAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ
:::: :. ...:. . :..:.. : ... :.
NP_000 DAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK
180 190 200 210
>>NP_000841 (OMIM: 138333) glutathione S-transferase Mu (218 aa)
initn: 317 init1: 158 opt: 345 Z-score: 447.1 bits: 89.8 E(85289): 3.6e-18
Smith-Waterman score: 345; 29.2% identity (62.7% similar) in 209 aa overlap (5-204:4-208)
10 20 30 40 50
pF1KB0 MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTV--------ETWQEGSLKASCLYGQ
:. :. .:: :.:.:: .:..:. :. : . ..: . . .
NP_000 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN
10 20 30 40 50
60 70 80 90 100 110
pF1KB0 LPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYT-N
:: . :: . :::.:: ...: .: :. ..: ::.... . :. . . :. .
NP_000 LPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB0 YEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCL
.: : .:.. :: ... : :: : . ..:::.:.:.:. :.: .:... :.::
NP_000 FEKLKPEYLEELPTMMQHF----SQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCL
120 130 140 150 160 170
180 190 200 210
pF1KB0 DAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ
:::: :. ...:. . :..:.. : ... :.
NP_000 DAFPNLKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK
180 190 200 210
>>NP_000842 (OMIM: 138385) glutathione S-transferase Mu (218 aa)
initn: 258 init1: 116 opt: 329 Z-score: 426.7 bits: 86.0 E(85289): 5e-17
Smith-Waterman score: 329; 30.0% identity (61.8% similar) in 207 aa overlap (3-200:2-204)
10 20 30 40 50
pF1KB0 MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTV--------ETWQEGSLKASCLYGQ
:.:. :. .:: :.:.:: .:. :. :. : . ..: . . .
NP_000 MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPN
10 20 30 40 50
60 70 80 90 100 110
pF1KB0 LPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYT-N
:: . :: . :::.:::...: .: :. ..: ::.... : : . . . : : .
NP_000 LPYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB0 YEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCL
.: : :.. :: .:: : :. : . ...::.:.:.:. :.: ..... : ::
NP_000 FEKLKPKYLEELPEKLK----LYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCL
120 130 140 150 160 170
180 190 200 210
pF1KB0 DAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ
::: :. ...:. . :..:.. : ...
NP_000 DAFLNLKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK
180 190 200 210
>>XP_005270841 (OMIM: 138385) PREDICTED: glutathione S-t (218 aa)
initn: 258 init1: 116 opt: 329 Z-score: 426.7 bits: 86.0 E(85289): 5e-17
Smith-Waterman score: 329; 30.0% identity (61.8% similar) in 207 aa overlap (3-200:2-204)
10 20 30 40 50
pF1KB0 MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTV--------ETWQEGSLKASCLYGQ
:.:. :. .:: :.:.:: .:. :. :. : . ..: . . .
XP_005 MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPN
10 20 30 40 50
60 70 80 90 100 110
pF1KB0 LPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYT-N
:: . :: . :::.:::...: .: :. ..: ::.... : : . . . : : .
XP_005 LPYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB0 YEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCL
.: : :.. :: .:: : :. : . ...::.:.:.:. :.: ..... : ::
XP_005 FEKLKPKYLEELPEKLK----LYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCL
120 130 140 150 160 170
180 190 200 210
pF1KB0 DAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ
::: :. ...:. . :..:.. : ...
XP_005 DAFLNLKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK
180 190 200 210
>>NP_000552 (OMIM: 138350) glutathione S-transferase Mu (218 aa)
initn: 234 init1: 92 opt: 327 Z-score: 424.1 bits: 85.5 E(85289): 6.9e-17
Smith-Waterman score: 327; 28.4% identity (62.1% similar) in 211 aa overlap (3-204:2-208)
10 20 30 40 50
pF1KB0 MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTV--------ETWQEGSLKASCLYGQ
:. . :. .:: :.:.:: .:..:. :. : . ..: . . .
NP_000 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN
10 20 30 40 50
60 70 80 90 100 110
pF1KB0 LPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYT-N
:: . :: . :::.:: ...: .: :. ..: ::.... . : . . . :. .
NP_000 LPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB0 YEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCL
.: : :.. :: .:: : :. : . ...:..:.:.:. . :.: .:... : ::
NP_000 FEKLKPKYLEELPEKLK----LYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCL
120 130 140 150 160 170
180 190 200 210
pF1KB0 DAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ
:::: :. ...:. . :..:.. : ... :.
NP_000 DAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
180 190 200 210
>>NP_001135840 (OMIM: 138380) glutathione S-transferase (191 aa)
initn: 276 init1: 143 opt: 325 Z-score: 422.4 bits: 85.0 E(85289): 8.6e-17
Smith-Waterman score: 325; 31.9% identity (62.8% similar) in 191 aa overlap (3-184:2-188)
10 20 30 40 50
pF1KB0 MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTV--------ETWQEGSLKASCLYGQ
:.:. :. .:: ..:.:: .:..:. :. : . ..: . . .
NP_001 MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN
10 20 30 40 50
60 70 80 90 100 110
pF1KB0 LPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYT-N
:: . :: . :::.:::...: .: :....: :.... : : . .: : .
NP_001 LPYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB0 YEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCL
.: : .:..::: .:: : :: : . ...::.:.:.:. :.: ..:. :.::
NP_001 FEKLKPEYLQALPEMLK----LYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCL
120 130 140 150 160 170
180 190 200 210
pF1KB0 DAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ
:::: :. ...:.
NP_001 DAFPNLKDFISRFEHS
180 190
>>NP_671489 (OMIM: 138333) glutathione S-transferase Mu (195 aa)
initn: 278 init1: 158 opt: 315 Z-score: 409.5 bits: 82.7 E(85289): 4.5e-16
Smith-Waterman score: 315; 30.2% identity (62.4% similar) in 189 aa overlap (5-184:4-188)
10 20 30 40 50
pF1KB0 MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTV--------ETWQEGSLKASCLYGQ
:. :. .:: :.:.:: .:..:. :. : . ..: . . .
NP_671 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN
10 20 30 40 50
60 70 80 90 100 110
pF1KB0 LPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYT-N
:: . :: . :::.:: ...: .: :. ..: ::.... . :. . . :. .
NP_671 LPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB0 YEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCL
.: : .:.. :: ... : :: : . ..:::.:.:.:. :.: .:... :.::
NP_671 FEKLKPEYLEELPTMMQHF----SQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCL
120 130 140 150 160 170
180 190 200 210
pF1KB0 DAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ
:::: :. ...:.
NP_671 DAFPNLKDFISRFEVSCGIM
180 190
>>XP_016856574 (OMIM: 138333) PREDICTED: glutathione S-t (254 aa)
initn: 278 init1: 158 opt: 315 Z-score: 407.8 bits: 82.7 E(85289): 5.6e-16
Smith-Waterman score: 315; 30.2% identity (62.4% similar) in 189 aa overlap (5-184:4-188)
10 20 30 40 50
pF1KB0 MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTV--------ETWQEGSLKASCLYGQ
:. :. .:: :.:.:: .:..:. :. : . ..: . . .
XP_016 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN
10 20 30 40 50
60 70 80 90 100 110
pF1KB0 LPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYT-N
:: . :: . :::.:: ...: .: :. ..: ::.... . :. . . :. .
XP_016 LPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB0 YEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCL
.: : .:.. :: ... : :: : . ..:::.:.:.:. :.: .:... :.::
XP_016 FEKLKPEYLEELPTMMQHF----SQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCL
120 130 140 150 160 170
180 190 200 210
pF1KB0 DAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ
:::: :. ...:.
XP_016 DAFPNLKDFISRFECSKCSPCEMSSTLILLLFTDLLLCMRQGVRHSGSCIDDCPILEMSA
180 190 200 210 220 230
210 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:35:53 2016 done: Sat Nov 5 17:35:53 2016
Total Scan time: 5.570 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]