Result of FASTA (ccds) for
pFN21AB6633
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6633, 417 aa
1>>>pF1KB6633 417 - 417 aa - 417 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0859+/-0.000775; mu= 10.4147+/- 0.047
mean_var=129.4673+/-26.100, 0's: 0 Z-trim(113.4): 12 B-trim: 487 in 1/53
Lambda= 0.112718
statistics sampled from 13991 (14000) to 13991 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.758), E-opt: 0.2 (0.43), width: 16
Scan time: 2.460
The best scores are: opt bits E(32554)
CCDS4129.1 LOX gene_id:4015|Hs108|chr5 ( 417) 2970 493.8 1.3e-139
CCDS10253.1 LOXL1 gene_id:4016|Hs108|chr15 ( 574) 1211 207.8 2.1e-53
CCDS74527.1 LOXL3 gene_id:84695|Hs108|chr2 ( 608) 775 137.0 4.9e-32
CCDS1953.1 LOXL3 gene_id:84695|Hs108|chr2 ( 753) 775 137.0 5.8e-32
CCDS7473.1 LOXL4 gene_id:84171|Hs108|chr10 ( 756) 765 135.4 1.8e-31
CCDS34864.1 LOXL2 gene_id:4017|Hs108|chr8 ( 774) 761 134.7 2.9e-31
>>CCDS4129.1 LOX gene_id:4015|Hs108|chr5 (417 aa)
initn: 2970 init1: 2970 opt: 2970 Z-score: 2620.1 bits: 493.8 E(32554): 1.3e-139
Smith-Waterman score: 2970; 100.0% identity (100.0% similar) in 417 aa overlap (1-417:1-417)
10 20 30 40 50 60
pF1KB6 MRFAWTVLLLGPLQLCALVHCAPPAAGQQQPPREPPAAPGAWRQQIQWENNGQVFSLLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 MRFAWTVLLLGPLQLCALVHCAPPAAGQQQPPREPPAAPGAWRQQIQWENNGQVFSLLSL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GSQYQPQRRRDPGAAVPGAANASAQQPRTPILLIRDNRTAAARTRTAGSSGVTAGRPRPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 GSQYQPQRRRDPGAAVPGAANASAQQPRTPILLIRDNRTAAARTRTAGSSGVTAGRPRPT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 ARHWFQAGYSTSRAREAGASRAENQTAPGEVPALSNLRPPSRVDGMVGDDPYNPYKYSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 ARHWFQAGYSTSRAREAGASRAENQTAPGEVPALSNLRPPSRVDGMVGDDPYNPYKYSDD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 NPYYNYYDTYERPRPGGRYRPGYGTGYFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 NPYYNYYDTYERPRPGGRYRPGYGTGYFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 EENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 EENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 FSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYGADID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 FSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYGADID
310 320 330 340 350 360
370 380 390 400 410
pF1KB6 CQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 CQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY
370 380 390 400 410
>>CCDS10253.1 LOXL1 gene_id:4016|Hs108|chr15 (574 aa)
initn: 1374 init1: 1168 opt: 1211 Z-score: 1072.2 bits: 207.8 E(32554): 2.1e-53
Smith-Waterman score: 1211; 64.4% identity (80.7% similar) in 270 aa overlap (149-414:308-571)
120 130 140 150 160 170
pF1KB6 PTARHWFQAGYSTSRAREAGASRAENQTAPGEVPALSNLRPPSRVDG--MVGDDPYNPYK
: : .: :: .. : . . :: : .
CCDS10 LYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPPYAN--PPPEAYGPPRALEPPYLPVR
280 290 300 310 320 330
180 190 200 210 220 230
pF1KB6 YSDDNPYYNYYDTYERPR--PGGRYRPGYGTGYFQYGLPDLVADPYYIQASTYVQKMSMY
:: : . . .. : :. :::. . :::::: :: :.:::::::. .:
CCDS10 SSDTPPPGGERNGAQQGRLSVGSVYRPNQNG----RGLPDLVPDPNYVQASTYVQRAHLY
340 350 360 370 380 390
240 250 260 270 280 290
pF1KB6 NLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQH
.:::::::.::::::: .. ::: :::::::::::::::.::::.:::..:::::::::
CCDS10 SLRCAAEEKCLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQH
400 410 420 430 440 450
300 310 320 330 340 350
pF1KB6 YHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDT
::::::::::::::: : ..:::::::::::::..::.: .:.:::.::::::::::::
CCDS10 YHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSHTQGLSPGCYDT
460 470 480 490 500 510
360 370 380 390 400 410
pF1KB6 YGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTI
:.:::::::::::::.:::::::: :::.:.: :::.:::::::.:.:::... :..: :
CCDS10 YNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKI
520 530 540 550 560 570
pF1KB6 SPY
CCDS10 VQS
>>CCDS74527.1 LOXL3 gene_id:84695|Hs108|chr2 (608 aa)
initn: 725 init1: 528 opt: 775 Z-score: 688.6 bits: 137.0 E(32554): 4.9e-32
Smith-Waterman score: 775; 49.5% identity (68.9% similar) in 222 aa overlap (194-414:368-584)
170 180 190 200 210 220
pF1KB6 DGMVGDDPYNPYKYSDDNPYYNYYDTYERPRPGGRYRPGYGTGYFQYGLPDLVADPYYIQ
: : :. : . ::. .:
CCDS74 TEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGV---ICSETASDLLLHSALVQ
340 350 360 370 380 390
230 240 250 260 270 280
pF1KB6 ASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPR
..:.. .. : ::::::::::.: :. : :: :::: ....: : .:: :. :
CCDS74 ETAYIEDRPLHMLYCAAEENCLASSARSANW-PYGHRRLLRFSSQIHNLGRADFRPKAGR
400 410 420 430 440 450
290 300 310 320 330 340
pF1KB6 YSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAH
.:: :: :: :::::: :.:::.: : . :::::::::::::: :. .:. :.
CCDS74 HSWVWHECHGHYHSMDIFTHYDILTPNGTK-VAEGHKASFCLEDTECQEDVSKRYECANF
460 470 480 490 500 510
350 360 370 380 390 400
pF1KB6 -TQGLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRY
::.. ::.: : :::::::::::::::::::.: .::.. : :::.:::...:. .:
CCDS74 GEQGITVGCWDLYRHDIDCQWIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKY
520 530 540 550 560 570
410
pF1KB6 TGHHAYASGCTISPY
::. .. .: :
CCDS74 DGHRIWVHNCHIGDAFSEEANRRFERYPGQTSNQII
580 590 600
>>CCDS1953.1 LOXL3 gene_id:84695|Hs108|chr2 (753 aa)
initn: 725 init1: 528 opt: 775 Z-score: 687.3 bits: 137.0 E(32554): 5.8e-32
Smith-Waterman score: 775; 49.5% identity (68.9% similar) in 222 aa overlap (194-414:513-729)
170 180 190 200 210 220
pF1KB6 DGMVGDDPYNPYKYSDDNPYYNYYDTYERPRPGGRYRPGYGTGYFQYGLPDLVADPYYIQ
: : :. : . ::. .:
CCDS19 TEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGV---ICSETASDLLLHSALVQ
490 500 510 520 530
230 240 250 260 270 280
pF1KB6 ASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPR
..:.. .. : ::::::::::.: :. : :: :::: ....: : .:: :. :
CCDS19 ETAYIEDRPLHMLYCAAEENCLASSARSANW-PYGHRRLLRFSSQIHNLGRADFRPKAGR
540 550 560 570 580 590
290 300 310 320 330 340
pF1KB6 YSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAH
.:: :: :: :::::: :.:::.: : . :::::::::::::: :. .:. :.
CCDS19 HSWVWHECHGHYHSMDIFTHYDILTPNGTK-VAEGHKASFCLEDTECQEDVSKRYECANF
600 610 620 630 640 650
350 360 370 380 390 400
pF1KB6 -TQGLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRY
::.. ::.: : :::::::::::::::::::.: .::.. : :::.:::...:. .:
CCDS19 GEQGITVGCWDLYRHDIDCQWIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKY
660 670 680 690 700 710
410
pF1KB6 TGHHAYASGCTISPY
::. .. .: :
CCDS19 DGHRIWVHNCHIGDAFSEEANRRFERYPGQTSNQII
720 730 740 750
>>CCDS7473.1 LOXL4 gene_id:84171|Hs108|chr10 (756 aa)
initn: 725 init1: 485 opt: 765 Z-score: 678.5 bits: 135.4 E(32554): 1.8e-31
Smith-Waterman score: 765; 49.5% identity (71.6% similar) in 218 aa overlap (196-412:519-731)
170 180 190 200 210 220
pF1KB6 MVGDDPYNPYKYSDDNPYYNYYDTYERPRPGGRYRPGYGTGYFQYGLPDLVADPYYIQAS
:::. : . . . :::: . .: .
CCDS74 EVVMSGVRCSGTELALQQCQRHGPVHCSHGGGRFLAGVSC---MDSAPDLVMNAQLVQET
490 500 510 520 530 540
230 240 250 260 270 280
pF1KB6 TYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYS
.:.. . .: :: :::::...: . : : .: :::: .. : : .:: :. : :
CCDS74 AYLEDRPLSQLYCAHEENCLSKSADHMDW-PYGYRRLLRFSTQIYNLGRTDFRPKTGRDS
550 560 570 580 590 600
290 300 310 320 330 340
pF1KB6 WEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAH-T
: ::.::.::::.. :.::::: : .. ::::::::::::::.: : .::.::.
CCDS74 WVWHQCHRHYHSIEVFTHYDLLTLNGSK-VAEGHKASFCLEDTNCPTGLQRRYACANFGE
610 620 630 640 650 660
350 360 370 380 390 400
pF1KB6 QGLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTG
::.. ::.::: ::::::.::::: :::::..: ::: : : :::..::...: .: :
CCDS74 QGVTVGCWDTYRHDIDCQWVDITDVGPGNYIFQVIVNPHYEVAESDFSNNMLQCRCKYDG
670 680 690 700 710 720
410
pF1KB6 HHAYASGCTISPY
:... .:
CCDS74 HRVWLHNCHTGNSYPANAELSLEQEQRLRNNLI
730 740 750
>>CCDS34864.1 LOXL2 gene_id:4017|Hs108|chr8 (774 aa)
initn: 707 init1: 492 opt: 761 Z-score: 674.8 bits: 134.7 E(32554): 2.9e-31
Smith-Waterman score: 761; 47.1% identity (72.4% similar) in 221 aa overlap (195-414:531-748)
170 180 190 200 210 220
pF1KB6 GMVGDDPYNPYKYSDDNPYYNYYDTYERPRPGGRYRPGYGTGYFQYGLPDLVADPYYIQA
: : . : :.. . . :::: . ..:
CCDS34 SNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSETA-PDLVLNAEMVQQ
510 520 530 540 550
230 240 250 260 270 280
pF1KB6 STYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRY
.::.. :. :.:: :::::...: ..: .: :::: ....:.: ::: :. :.
CCDS34 TTYLEDRPMFMLQCAMEENCLSASAAQTDPTT-GYRRLLRFSSQIHNNGQSDFRPKNGRH
560 570 580 590 600 610
290 300 310 320 330 340
pF1KB6 SWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAH-
.: ::.::.:::::. :.:::::. : . :::::::::::::: :. .. . :.
CCDS34 AWIWHDCHRHYHSMEVFTHYDLLNLNGTK-VAEGHKASFCLEDTECEGDIQKNYECANFG
620 630 640 650 660 670
350 360 370 380 390 400
pF1KB6 TQGLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYT
::.. ::.: : ::::::.::::: ::.:...: .::.. : ::::.::...: ::
CCDS34 DQGITMGCWDMYRHDIDCQWVDITDVPPGDYLFQVVINPNFEVAESDYSNNIMKCRSRYD
680 690 700 710 720 730
410
pF1KB6 GHHAYASGCTISPY
::. . .: :
CCDS34 GHRIWMYNCHIGGSFSEETEKKFEHFSGLLNNQLSPQ
740 750 760 770
417 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:26:44 2016 done: Sat Nov 5 17:26:45 2016
Total Scan time: 2.460 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]