Result of FASTA (omim) for
pFN21AB0951
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0951, 183 aa
1>>>pF1KB0951 183 - 183 aa - 183 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3308+/-0.000485; mu= 12.2651+/- 0.030
mean_var=72.2982+/-14.556, 0's: 0 Z-trim(110.7): 419 B-trim: 1175 in 3/51
Lambda= 0.150838
statistics sampled from 18650 (19135) to 18650 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.224), width: 16
Scan time: 5.090
The best scores are: opt bits E(85289)
NP_005605 (OMIM: 601293) GTP-binding protein Rheb ( 184) 657 152.3 4.1e-37
XP_011514759 (OMIM: 601293) PREDICTED: GTP-binding ( 173) 594 138.6 5.3e-33
NP_066361 (OMIM: 179540) ras-related protein Rap-2 ( 183) 424 101.6 7.6e-22
NP_002877 (OMIM: 179541) ras-related protein Rap-2 ( 183) 422 101.1 1e-21
NP_060064 (OMIM: 607863) GTP-binding protein Di-Ra ( 199) 391 94.4 1.2e-19
NP_001010942 (OMIM: 179530) ras-related protein Ra ( 184) 389 94.0 1.5e-19
NP_056461 (OMIM: 179530) ras-related protein Rap-1 ( 184) 389 94.0 1.5e-19
NP_001010935 (OMIM: 179520) ras-related protein Ra ( 184) 387 93.5 2e-19
XP_016857451 (OMIM: 179520) PREDICTED: ras-related ( 184) 387 93.5 2e-19
XP_016857453 (OMIM: 179520) PREDICTED: ras-related ( 184) 387 93.5 2e-19
XP_016857452 (OMIM: 179520) PREDICTED: ras-related ( 184) 387 93.5 2e-19
NP_001278825 (OMIM: 179520) ras-related protein Ra ( 184) 387 93.5 2e-19
NP_002875 (OMIM: 179520) ras-related protein Rap-1 ( 184) 387 93.5 2e-19
XP_016857449 (OMIM: 179520) PREDICTED: ras-related ( 195) 355 86.6 2.6e-17
XP_016857450 (OMIM: 179520) PREDICTED: ras-related ( 195) 355 86.6 2.6e-17
NP_005393 (OMIM: 179550) ras-related protein Ral-A ( 206) 355 86.6 2.8e-17
XP_006715825 (OMIM: 179550) PREDICTED: ras-related ( 206) 355 86.6 2.8e-17
XP_011513768 (OMIM: 179550) PREDICTED: ras-related ( 206) 355 86.6 2.8e-17
XP_006719132 (OMIM: 109800,114480,137215,163200,19 ( 189) 353 86.1 3.5e-17
NP_203524 (OMIM: 109800,114480,137215,163200,19007 ( 189) 353 86.1 3.5e-17
NP_036382 (OMIM: 600098) ras-related protein R-Ras ( 204) 353 86.2 3.7e-17
NP_004976 (OMIM: 109800,114480,137215,163200,19007 ( 188) 352 85.9 4e-17
XP_011518955 (OMIM: 109800,114480,137215,163200,19 ( 188) 352 85.9 4e-17
XP_016874782 (OMIM: 109800,114480,137215,163200,19 ( 227) 353 86.2 4e-17
NP_071894 (OMIM: 602206) ras-related protein Rab-1 ( 212) 352 85.9 4.4e-17
XP_005263785 (OMIM: 179551) PREDICTED: ras-related ( 206) 347 84.9 9.2e-17
XP_016860111 (OMIM: 179551) PREDICTED: ras-related ( 206) 347 84.9 9.2e-17
XP_005263784 (OMIM: 179551) PREDICTED: ras-related ( 206) 347 84.9 9.2e-17
XP_005263786 (OMIM: 179551) PREDICTED: ras-related ( 206) 347 84.9 9.2e-17
NP_002872 (OMIM: 179551) ras-related protein Ral-B ( 206) 347 84.9 9.2e-17
NP_008843 (OMIM: 609591,615355) GTP-binding protei ( 219) 347 84.9 9.7e-17
NP_002515 (OMIM: 114500,137550,162900,163200,16479 ( 189) 346 84.6 1e-16
XP_016860110 (OMIM: 179551) PREDICTED: ras-related ( 228) 347 84.9 1e-16
XP_005263781 (OMIM: 179551) PREDICTED: ras-related ( 228) 347 84.9 1e-16
XP_011509875 (OMIM: 179551) PREDICTED: ras-related ( 229) 347 84.9 1e-16
NP_001243750 (OMIM: 609591,615355) GTP-binding pro ( 236) 347 84.9 1e-16
NP_002921 (OMIM: 609592) GTP-binding protein Rit2 ( 217) 346 84.7 1.1e-16
NP_005334 (OMIM: 109800,137550,162900,163200,18847 ( 189) 343 84.0 1.6e-16
NP_001123914 (OMIM: 109800,137550,162900,163200,18 ( 189) 343 84.0 1.6e-16
NP_660156 (OMIM: 607862) GTP-binding protein Di-Ra ( 198) 339 83.1 3e-16
XP_011526015 (OMIM: 607862) PREDICTED: GTP-binding ( 232) 339 83.1 3.4e-16
NP_006261 (OMIM: 165090) ras-related protein R-Ras ( 218) 335 82.3 5.9e-16
NP_789765 (OMIM: 109800,137550,162900,163200,18847 ( 170) 325 80.0 2.2e-15
NP_996563 (OMIM: 612403) ras-like protein family m ( 242) 325 80.1 2.9e-15
XP_016858262 (OMIM: 605193) PREDICTED: GTP-binding ( 229) 318 78.6 8e-15
NP_004666 (OMIM: 605193) GTP-binding protein Di-Ra ( 229) 318 78.6 8e-15
NP_116307 (OMIM: 612664) ras-related and estrogen- ( 199) 310 76.8 2.4e-14
NP_065120 (OMIM: 612942) ras-related protein Rab-2 ( 213) 306 75.9 4.6e-14
NP_055814 (OMIM: 612398) ras-related protein Rab-2 ( 225) 304 75.5 6.5e-14
XP_011509876 (OMIM: 179551) PREDICTED: ras-related ( 195) 303 75.3 6.7e-14
>>NP_005605 (OMIM: 601293) GTP-binding protein Rheb [Hom (184 aa)
initn: 618 init1: 618 opt: 657 Z-score: 787.2 bits: 152.3 E(85289): 4.1e-37
Smith-Waterman score: 657; 52.2% identity (81.5% similar) in 184 aa overlap (1-183:1-184)
10 20 30 40 50 60
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
:: . ::..::::: :::.::. :::::.: ..::::.:::..:..:.. .:.::.:::
NP_005 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
:::::::::.: .. : ..::.:::::::..::.::. .. :: . ::...:..:::::
NP_005 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK
70 80 90 100 110 120
130 140 150 160 170
pF1KB0 ADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQERR-
:: :: .. ::: :::::.:.:.::::.::: . .: ..: : ..... .: .
NP_005 KDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSS
130 140 150 160 170 180
180
pF1KB0 CHLM
: .:
NP_005 CSVM
>>XP_011514759 (OMIM: 601293) PREDICTED: GTP-binding pro (173 aa)
initn: 551 init1: 551 opt: 594 Z-score: 713.5 bits: 138.6 E(85289): 5.3e-33
Smith-Waterman score: 594; 50.3% identity (80.9% similar) in 173 aa overlap (12-183:1-173)
10 20 30 40 50 60
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
.: .::.::. :::::.: ..::::.:::..:..:.. .:.::.:::
XP_011 MGTFNLGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD
10 20 30 40
70 80 90 100 110 120
pF1KB0 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
:::::::::.: .. : ..::.:::::::..::.::. .. :: . ::...:..:::::
XP_011 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK
50 60 70 80 90 100
130 140 150 160 170
pF1KB0 ADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQERR-
:: :: .. ::: :::::.:.:.::::.::: . .: ..: : ..... .: .
XP_011 KDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSS
110 120 130 140 150 160
180
pF1KB0 CHLM
: .:
XP_011 CSVM
170
>>NP_066361 (OMIM: 179540) ras-related protein Rap-2a pr (183 aa)
initn: 434 init1: 419 opt: 424 Z-score: 513.2 bits: 101.6 E(85289): 7.6e-22
Smith-Waterman score: 424; 39.6% identity (73.2% similar) in 164 aa overlap (4-167:1-164)
10 20 30 40 50 60
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
.: :::.:: :::..:. ::: : : : ::::.:. : : . . .. :...:
NP_066 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB0 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
::: .... . .: . .:..::::... .::: :. . ... . . .:::.:::::
NP_066 TAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB0 ADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQERRC
.:: ::::.. ::. ::: :: :::.::. . ... .:.......
NP_066 VDLESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCC
120 130 140 150 160 170
pF1KB0 HLM
NP_066 SACNIQ
180
>>NP_002877 (OMIM: 179541) ras-related protein Rap-2b [H (183 aa)
initn: 386 init1: 386 opt: 422 Z-score: 510.9 bits: 101.1 E(85289): 1e-21
Smith-Waterman score: 422; 38.4% identity (70.6% similar) in 177 aa overlap (4-180:1-177)
10 20 30 40 50 60
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
.: :::.:: :::..:. ::: : : : ::::.:. : : . . .. :...:
NP_002 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB0 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
::: .... . .: . .:..::::... .::: :. . ... . . :::..:::::
NP_002 TAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB0 ADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQERRC
.:: ::::. ::: ::: :. :::.::... .. .:....... . . :.: :
NP_002 VDLEGEREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEGCC
120 130 140 150 160 170
pF1KB0 HLM
NP_002 SACVIL
180
>>NP_060064 (OMIM: 607863) GTP-binding protein Di-Ras2 [ (199 aa)
initn: 381 init1: 220 opt: 391 Z-score: 473.9 bits: 94.4 E(85289): 1.2e-19
Smith-Waterman score: 391; 38.0% identity (74.1% similar) in 158 aa overlap (8-164:9-166)
10 20 30 40 50
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLV
.:...: :::.::. .::.: : :.: ::::.:: .... :. :...
NP_060 MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQIT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB0 DTAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTR-VPVVLVG
::.:. .. . : :...::::.:: .:.. .. .:... : .: .. .:..:::
NP_060 DTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB0 NKADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQER
:: : :: ::::. :.. ::..: .:::.::. :. .. .: ...
NP_060 NKCDESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDG
130 140 150 160 170 180
180
pF1KB0 RCHLM
NP_060 KKSKQQKRKEKLKGKCVIM
190
>>NP_001010942 (OMIM: 179530) ras-related protein Rap-1b (184 aa)
initn: 342 init1: 314 opt: 389 Z-score: 472.0 bits: 94.0 E(85289): 1.5e-19
Smith-Waterman score: 389; 35.3% identity (68.5% similar) in 184 aa overlap (4-183:1-184)
10 20 30 40 50 60
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
.: :.:.:: :::..:. :::.: : : ::::.:..: : : . .. :...:
NP_001 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB0 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
::: .... . .. . .:..::::.:. .:. ...: ... . . ::..:::::
NP_001 TAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNK
60 70 80 90 100 110
130 140 150 160 170
pF1KB0 ADLSPEREVQAVEGKKLAESWGA-TFMESSARENQLTQGIFTKVIQEIARVENSYGQERR
:: :: : .:..::..:. .:.::::. . .. :: ....: : :. :.
NP_001 CDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARK
120 130 140 150 160 170
180
pF1KB0 ---CHLM
:.:.
NP_001 KSSCQLL
180
>>NP_056461 (OMIM: 179530) ras-related protein Rap-1b is (184 aa)
initn: 342 init1: 314 opt: 389 Z-score: 472.0 bits: 94.0 E(85289): 1.5e-19
Smith-Waterman score: 389; 35.3% identity (68.5% similar) in 184 aa overlap (4-183:1-184)
10 20 30 40 50 60
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
.: :.:.:: :::..:. :::.: : : ::::.:..: : : . .. :...:
NP_056 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB0 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
::: .... . .. . .:..::::.:. .:. ...: ... . . ::..:::::
NP_056 TAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNK
60 70 80 90 100 110
130 140 150 160 170
pF1KB0 ADLSPEREVQAVEGKKLAESWGA-TFMESSARENQLTQGIFTKVIQEIARVENSYGQERR
:: :: : .:..::..:. .:.::::. . .. :: ....: : :. :.
NP_056 CDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARK
120 130 140 150 160 170
180
pF1KB0 ---CHLM
:.:.
NP_056 KSSCQLL
180
>>NP_001010935 (OMIM: 179520) ras-related protein Rap-1A (184 aa)
initn: 340 init1: 312 opt: 387 Z-score: 469.7 bits: 93.5 E(85289): 2e-19
Smith-Waterman score: 387; 35.3% identity (69.6% similar) in 184 aa overlap (4-183:1-184)
10 20 30 40 50 60
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
.: :.:.:: :::..:. :::.: : : ::::.:..: : : . .. :...:
NP_001 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB0 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
::: .... . .. . .:..::::.:. .:. ...: ... . . ::..:::::
NP_001 TAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNK
60 70 80 90 100 110
130 140 150 160 170
pF1KB0 ADLSPEREVQAVEGKKLAESW-GATFMESSARENQLTQGIFTKVIQEIAR---VENSYGQ
:: :: : .:..::..: . .:.::::. . .. :: ....: : ::.. .
NP_001 CDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPK
120 130 140 150 160 170
180
pF1KB0 ERRCHLM
.. : :.
NP_001 KKSCLLL
180
>>XP_016857451 (OMIM: 179520) PREDICTED: ras-related pro (184 aa)
initn: 340 init1: 312 opt: 387 Z-score: 469.7 bits: 93.5 E(85289): 2e-19
Smith-Waterman score: 387; 35.3% identity (69.6% similar) in 184 aa overlap (4-183:1-184)
10 20 30 40 50 60
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
.: :.:.:: :::..:. :::.: : : ::::.:..: : : . .. :...:
XP_016 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB0 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
::: .... . .. . .:..::::.:. .:. ...: ... . . ::..:::::
XP_016 TAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNK
60 70 80 90 100 110
130 140 150 160 170
pF1KB0 ADLSPEREVQAVEGKKLAESW-GATFMESSARENQLTQGIFTKVIQEIAR---VENSYGQ
:: :: : .:..::..: . .:.::::. . .. :: ....: : ::.. .
XP_016 CDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPK
120 130 140 150 160 170
180
pF1KB0 ERRCHLM
.. : :.
XP_016 KKSCLLL
180
>>XP_016857453 (OMIM: 179520) PREDICTED: ras-related pro (184 aa)
initn: 340 init1: 312 opt: 387 Z-score: 469.7 bits: 93.5 E(85289): 2e-19
Smith-Waterman score: 387; 35.3% identity (69.6% similar) in 184 aa overlap (4-183:1-184)
10 20 30 40 50 60
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
.: :.:.:: :::..:. :::.: : : ::::.:..: : : . .. :...:
XP_016 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB0 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
::: .... . .. . .:..::::.:. .:. ...: ... . . ::..:::::
XP_016 TAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNK
60 70 80 90 100 110
130 140 150 160 170
pF1KB0 ADLSPEREVQAVEGKKLAESW-GATFMESSARENQLTQGIFTKVIQEIAR---VENSYGQ
:: :: : .:..::..: . .:.::::. . .. :: ....: : ::.. .
XP_016 CDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPK
120 130 140 150 160 170
180
pF1KB0 ERRCHLM
.. : :.
XP_016 KKSCLLL
180
183 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:26:13 2016 done: Sat Nov 5 17:26:14 2016
Total Scan time: 5.090 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]