Result of FASTA (ccds) for
pFN21AB0951
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0951, 183 aa
1>>>pF1KB0951 183 - 183 aa - 183 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1579+/-0.00105; mu= 13.1882+/- 0.064
mean_var=68.6200+/-13.710, 0's: 0 Z-trim(103.9): 191 B-trim: 451 in 2/49
Lambda= 0.154828
statistics sampled from 7430 (7645) to 7430 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.235), width: 16
Scan time: 1.520
The best scores are: opt bits E(32554)
CCDS8778.1 RHEBL1 gene_id:121268|Hs108|chr12 ( 183) 1194 275.7 1.1e-74
CCDS5927.1 RHEB gene_id:6009|Hs108|chr7 ( 184) 657 155.8 1.4e-38
CCDS14632.1 RAP2C gene_id:57826|Hs108|chrX ( 183) 433 105.7 1.6e-23
CCDS9485.1 RAP2A gene_id:5911|Hs108|chr13 ( 183) 424 103.7 6.5e-23
CCDS3170.1 RAP2B gene_id:5912|Hs108|chr3 ( 183) 422 103.3 8.9e-23
CCDS6687.1 DIRAS2 gene_id:54769|Hs108|chr9 ( 199) 391 96.4 1.2e-20
CCDS8984.1 RAP1B gene_id:5908|Hs108|chr12 ( 184) 389 95.9 1.5e-20
CCDS840.1 RAP1A gene_id:5906|Hs108|chr1 ( 184) 387 95.5 2e-20
CCDS5460.1 RALA gene_id:5898|Hs108|chr7 ( 206) 355 88.3 3.1e-18
CCDS8703.1 KRAS gene_id:3845|Hs108|chr12 ( 189) 353 87.9 4e-18
CCDS7814.1 RRAS2 gene_id:22800|Hs108|chr11 ( 204) 353 87.9 4.2e-18
CCDS8702.1 KRAS gene_id:3845|Hs108|chr12 ( 188) 352 87.6 4.6e-18
CCDS2520.1 RAB17 gene_id:64284|Hs108|chr2 ( 212) 352 87.7 5.1e-18
CCDS2131.1 RALB gene_id:5899|Hs108|chr2 ( 206) 347 86.6 1.1e-17
CCDS1123.1 RIT1 gene_id:6016|Hs108|chr1 ( 219) 347 86.6 1.1e-17
CCDS877.1 NRAS gene_id:4893|Hs108|chr1 ( 189) 346 86.3 1.2e-17
CCDS58037.1 RIT1 gene_id:6016|Hs108|chr1 ( 236) 347 86.6 1.2e-17
CCDS11921.1 RIT2 gene_id:6014|Hs108|chr18 ( 217) 346 86.3 1.3e-17
CCDS7698.1 HRAS gene_id:3265|Hs108|chr11 ( 189) 343 85.6 1.9e-17
CCDS12092.1 DIRAS1 gene_id:148252|Hs108|chr19 ( 198) 339 84.8 3.6e-17
CCDS12774.1 RRAS gene_id:6237|Hs108|chr19 ( 218) 335 83.9 7.3e-17
CCDS7699.1 HRAS gene_id:3265|Hs108|chr11 ( 170) 325 81.6 2.8e-16
CCDS9321.1 RASL11A gene_id:387496|Hs108|chr13 ( 242) 325 81.7 3.7e-16
CCDS641.1 DIRAS3 gene_id:9077|Hs108|chr1 ( 229) 318 80.1 1.1e-15
CCDS8673.1 RERG gene_id:85004|Hs108|chr12 ( 199) 310 78.3 3.2e-15
CCDS41413.1 RAB25 gene_id:57111|Hs108|chr1 ( 213) 306 77.4 6.4e-15
CCDS9003.1 RAB21 gene_id:23011|Hs108|chr12 ( 225) 304 77.0 9.1e-15
CCDS3100.1 MRAS gene_id:22808|Hs108|chr3 ( 208) 303 76.7 9.9e-15
CCDS45826.1 RAB31 gene_id:11031|Hs108|chr18 ( 195) 301 76.3 1.3e-14
CCDS58036.1 RIT1 gene_id:6016|Hs108|chr1 ( 183) 299 75.8 1.7e-14
CCDS53603.1 RRAS2 gene_id:22800|Hs108|chr11 ( 169) 295 74.9 2.9e-14
CCDS11703.1 RAB37 gene_id:326624|Hs108|chr17 ( 216) 296 75.2 3e-14
CCDS8223.1 RAB6A gene_id:5870|Hs108|chr11 ( 208) 292 74.3 5.4e-14
CCDS3082.1 RAB6B gene_id:51560|Hs108|chr3 ( 208) 288 73.4 1e-13
CCDS62431.1 RIT2 gene_id:6014|Hs108|chr18 ( 153) 286 72.8 1.1e-13
CCDS82198.1 RAB37 gene_id:326624|Hs108|chr17 ( 196) 287 73.1 1.1e-13
CCDS8224.1 RAB6A gene_id:5870|Hs108|chr11 ( 208) 287 73.2 1.2e-13
CCDS32722.1 RAB37 gene_id:326624|Hs108|chr17 ( 223) 287 73.2 1.2e-13
CCDS54161.1 RAB37 gene_id:326624|Hs108|chr17 ( 228) 287 73.2 1.3e-13
CCDS12257.1 RAB3D gene_id:9545|Hs108|chr19 ( 219) 286 72.9 1.4e-13
CCDS560.1 RAB3B gene_id:5865|Hs108|chr1 ( 219) 284 72.5 2e-13
CCDS6175.1 RAB2A gene_id:5862|Hs108|chr8 ( 212) 283 72.3 2.2e-13
CCDS33497.1 RAB22A gene_id:57403|Hs108|chr20 ( 194) 282 72.0 2.4e-13
CCDS12372.1 RAB3A gene_id:5864|Hs108|chr19 ( 220) 281 71.8 3.1e-13
CCDS3976.1 RAB3C gene_id:115827|Hs108|chr5 ( 227) 281 71.8 3.2e-13
CCDS9570.1 RAB2B gene_id:84932|Hs108|chr14 ( 216) 280 71.6 3.6e-13
CCDS10200.1 RASL12 gene_id:51285|Hs108|chr15 ( 266) 281 71.9 3.6e-13
CCDS10460.1 RAB26 gene_id:25837|Hs108|chr16 ( 256) 280 71.6 4.1e-13
CCDS14766.1 RAB39B gene_id:116442|Hs108|chrX ( 213) 279 71.4 4.2e-13
CCDS33030.1 RAB4B gene_id:53916|Hs108|chr19 ( 213) 278 71.1 4.9e-13
>>CCDS8778.1 RHEBL1 gene_id:121268|Hs108|chr12 (183 aa)
initn: 1194 init1: 1194 opt: 1194 Z-score: 1454.3 bits: 275.7 E(32554): 1.1e-74
Smith-Waterman score: 1194; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183)
10 20 30 40 50 60
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS87 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS87 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 ADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQERRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS87 ADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQERRC
130 140 150 160 170 180
pF1KB0 HLM
:::
CCDS87 HLM
>>CCDS5927.1 RHEB gene_id:6009|Hs108|chr7 (184 aa)
initn: 618 init1: 618 opt: 657 Z-score: 806.0 bits: 155.8 E(32554): 1.4e-38
Smith-Waterman score: 657; 52.2% identity (81.5% similar) in 184 aa overlap (1-183:1-184)
10 20 30 40 50 60
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
:: . ::..::::: :::.::. :::::.: ..::::.:::..:..:.. .:.::.:::
CCDS59 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
:::::::::.: .. : ..::.:::::::..::.::. .. :: . ::...:..:::::
CCDS59 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK
70 80 90 100 110 120
130 140 150 160 170
pF1KB0 ADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQERR-
:: :: .. ::: :::::.:.:.::::.::: . .: ..: : ..... .: .
CCDS59 KDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSS
130 140 150 160 170 180
180
pF1KB0 CHLM
: .:
CCDS59 CSVM
>>CCDS14632.1 RAP2C gene_id:57826|Hs108|chrX (183 aa)
initn: 423 init1: 423 opt: 433 Z-score: 535.7 bits: 105.7 E(32554): 1.6e-23
Smith-Waterman score: 433; 37.3% identity (71.2% similar) in 177 aa overlap (4-180:1-177)
10 20 30 40 50 60
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
.: :::.:: :::..:. ::: : : : ::::.:. : : . . .. :...:
CCDS14 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB0 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
::: .... . .: . .:..::::... .::: :. . ... . . .::..:::::
CCDS14 TAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB0 ADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQERRC
.:: :::::.. ::. ::. :: :::.::. ..... .:....... :.. :
CCDS14 VDLEPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQCC
120 130 140 150 160 170
pF1KB0 HLM
CCDS14 TTCVVQ
180
>>CCDS9485.1 RAP2A gene_id:5911|Hs108|chr13 (183 aa)
initn: 434 init1: 419 opt: 424 Z-score: 524.8 bits: 103.7 E(32554): 6.5e-23
Smith-Waterman score: 424; 39.6% identity (73.2% similar) in 164 aa overlap (4-167:1-164)
10 20 30 40 50 60
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
.: :::.:: :::..:. ::: : : : ::::.:. : : . . .. :...:
CCDS94 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB0 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
::: .... . .: . .:..::::... .::: :. . ... . . .:::.:::::
CCDS94 TAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB0 ADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQERRC
.:: ::::.. ::. ::: :: :::.::. . ... .:.......
CCDS94 VDLESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCC
120 130 140 150 160 170
pF1KB0 HLM
CCDS94 SACNIQ
180
>>CCDS3170.1 RAP2B gene_id:5912|Hs108|chr3 (183 aa)
initn: 386 init1: 386 opt: 422 Z-score: 522.4 bits: 103.3 E(32554): 8.9e-23
Smith-Waterman score: 422; 38.4% identity (70.6% similar) in 177 aa overlap (4-180:1-177)
10 20 30 40 50 60
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
.: :::.:: :::..:. ::: : : : ::::.:. : : . . .. :...:
CCDS31 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB0 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
::: .... . .: . .:..::::... .::: :. . ... . . :::..:::::
CCDS31 TAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB0 ADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQERRC
.:: ::::. ::: ::: :. :::.::... .. .:....... . . :.: :
CCDS31 VDLEGEREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEGCC
120 130 140 150 160 170
pF1KB0 HLM
CCDS31 SACVIL
180
>>CCDS6687.1 DIRAS2 gene_id:54769|Hs108|chr9 (199 aa)
initn: 381 init1: 220 opt: 391 Z-score: 484.4 bits: 96.4 E(32554): 1.2e-20
Smith-Waterman score: 391; 38.0% identity (74.1% similar) in 158 aa overlap (8-164:9-166)
10 20 30 40 50
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLV
.:...: :::.::. .::.: : :.: ::::.:: .... :. :...
CCDS66 MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQIT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB0 DTAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTR-VPVVLVG
::.:. .. . : :...::::.:: .:.. .. .:... : .: .. .:..:::
CCDS66 DTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB0 NKADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQER
:: : :: ::::. :.. ::..: .:::.::. :. .. .: ...
CCDS66 NKCDESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDG
130 140 150 160 170 180
180
pF1KB0 RCHLM
CCDS66 KKSKQQKRKEKLKGKCVIM
190
>>CCDS8984.1 RAP1B gene_id:5908|Hs108|chr12 (184 aa)
initn: 342 init1: 314 opt: 389 Z-score: 482.5 bits: 95.9 E(32554): 1.5e-20
Smith-Waterman score: 389; 35.3% identity (68.5% similar) in 184 aa overlap (4-183:1-184)
10 20 30 40 50 60
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
.: :.:.:: :::..:. :::.: : : ::::.:..: : : . .. :...:
CCDS89 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB0 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
::: .... . .. . .:..::::.:. .:. ...: ... . . ::..:::::
CCDS89 TAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNK
60 70 80 90 100 110
130 140 150 160 170
pF1KB0 ADLSPEREVQAVEGKKLAESWGA-TFMESSARENQLTQGIFTKVIQEIARVENSYGQERR
:: :: : .:..::..:. .:.::::. . .. :: ....: : :. :.
CCDS89 CDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARK
120 130 140 150 160 170
180
pF1KB0 ---CHLM
:.:.
CCDS89 KSSCQLL
180
>>CCDS840.1 RAP1A gene_id:5906|Hs108|chr1 (184 aa)
initn: 340 init1: 312 opt: 387 Z-score: 480.1 bits: 95.5 E(32554): 2e-20
Smith-Waterman score: 387; 35.3% identity (69.6% similar) in 184 aa overlap (4-183:1-184)
10 20 30 40 50 60
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
.: :.:.:: :::..:. :::.: : : ::::.:..: : : . .. :...:
CCDS84 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB0 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
::: .... . .. . .:..::::.:. .:. ...: ... . . ::..:::::
CCDS84 TAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNK
60 70 80 90 100 110
130 140 150 160 170
pF1KB0 ADLSPEREVQAVEGKKLAESW-GATFMESSARENQLTQGIFTKVIQEIAR---VENSYGQ
:: :: : .:..::..: . .:.::::. . .. :: ....: : ::.. .
CCDS84 CDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPK
120 130 140 150 160 170
180
pF1KB0 ERRCHLM
.. : :.
CCDS84 KKSCLLL
180
>>CCDS5460.1 RALA gene_id:5898|Hs108|chr7 (206 aa)
initn: 349 init1: 349 opt: 355 Z-score: 440.8 bits: 88.3 E(32554): 3.1e-18
Smith-Waterman score: 355; 33.9% identity (70.6% similar) in 180 aa overlap (8-182:16-195)
10 20 30 40 50
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKD
::...: :::..:. ::. :: : :.:: ..: : :.: .
CCDS54 MAANKPKGQNSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB0 EFHLHLVDTAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRV
: .. ..:::::..:. . ... . .:.. :.:.: ..:: . .. ... . . :
CCDS54 EVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB0 PVVLVGNKADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEI-AR-V
: .:::::.:: .:.:.. :.:. ::.:.....:.::. .. .: ...:: :: .
CCDS54 PFLLVGNKSDLEDKRQVSVEEAKNRAEQWNVNYVETSAKTRANVDKVFFDLMREIRARKM
130 140 150 160 170 180
180
pF1KB0 ENSY---GQERRCHLM
:.: :...: :
CCDS54 EDSKEKNGKKKRKSLAKRIRERCCIL
190 200
>>CCDS8703.1 KRAS gene_id:3845|Hs108|chr12 (189 aa)
initn: 334 init1: 250 opt: 353 Z-score: 438.9 bits: 87.9 E(32554): 4e-18
Smith-Waterman score: 353; 35.0% identity (71.9% similar) in 160 aa overlap (8-167:5-163)
10 20 30 40 50 60
pF1KB0 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVD
:.:..: :::..:. :.....: . ::::.:..: : :.. . : ..:
CCDS87 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB0 TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNK
::::.::: . ... .:.. :..... .::. :. ..... . . ::.::::::
CCDS87 TAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB0 ADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQERRC
:: : : :.. ... ::.:.: :.:.::. : .. : ...::
CCDS87 CDL-PSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEK
120 130 140 150 160 170
pF1KB0 HLM
CCDS87 TPGCVKIKKCIIM
180
183 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:26:12 2016 done: Sat Nov 5 17:26:13 2016
Total Scan time: 1.520 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]