Result of FASTA (omim) for
pFN21AB6523
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6523, 364 aa
1>>>pF1KB6523 364 - 364 aa - 364 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4825+/-0.000317; mu= 8.8765+/- 0.020
mean_var=230.6675+/-50.921, 0's: 0 Z-trim(122.8): 91 B-trim: 2195 in 1/58
Lambda= 0.084446
statistics sampled from 41425 (41578) to 41425 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.791), E-opt: 0.2 (0.487), width: 16
Scan time: 9.010
The best scores are: opt bits E(85289)
NP_659501 (OMIM: 255995,615521) SH3 and cysteine-r ( 364) 2515 318.8 1.2e-86
XP_011536428 (OMIM: 255995,615521) PREDICTED: SH3 ( 364) 2515 318.8 1.2e-86
NP_001273185 (OMIM: 255995,615521) SH3 and cystein ( 325) 2269 288.8 1.2e-77
NP_001273186 (OMIM: 255995,615521) SH3 and cystein ( 178) 1214 159.9 3.9e-39
XP_016862573 (OMIM: 602317) PREDICTED: SH3 and cys ( 215) 431 64.7 2.3e-10
XP_016862572 (OMIM: 602317) PREDICTED: SH3 and cys ( 334) 431 64.9 3e-10
XP_011532340 (OMIM: 602317) PREDICTED: SH3 and cys ( 334) 431 64.9 3e-10
NP_001278978 (OMIM: 602317) SH3 and cysteine-rich ( 341) 431 64.9 3.1e-10
XP_011532339 (OMIM: 602317) PREDICTED: SH3 and cys ( 391) 431 65.0 3.3e-10
NP_003140 (OMIM: 602317) SH3 and cysteine-rich dom ( 402) 431 65.0 3.4e-10
XP_011532338 (OMIM: 602317) PREDICTED: SH3 and cys ( 406) 431 65.0 3.4e-10
>>NP_659501 (OMIM: 255995,615521) SH3 and cysteine-rich (364 aa)
initn: 2515 init1: 2515 opt: 2515 Z-score: 1676.6 bits: 318.8 E(85289): 1.2e-86
Smith-Waterman score: 2515; 100.0% identity (100.0% similar) in 364 aa overlap (1-364:1-364)
10 20 30 40 50 60
pF1KB6 MTEKEVLESPKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQANGEAVGAGGGPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 MTEKEVLESPKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQANGEAVGAGGGPI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 YYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 KNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFET
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LRTGVIMANKERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 LRTGVIMANKERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 HKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 HKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 IIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 IIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDF
310 320 330 340 350 360
pF1KB6 LEEI
::::
NP_659 LEEI
>>XP_011536428 (OMIM: 255995,615521) PREDICTED: SH3 and (364 aa)
initn: 2515 init1: 2515 opt: 2515 Z-score: 1676.6 bits: 318.8 E(85289): 1.2e-86
Smith-Waterman score: 2515; 100.0% identity (100.0% similar) in 364 aa overlap (1-364:1-364)
10 20 30 40 50 60
pF1KB6 MTEKEVLESPKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQANGEAVGAGGGPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTEKEVLESPKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQANGEAVGAGGGPI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFET
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LRTGVIMANKERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRTGVIMANKERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 HKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 IIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDF
310 320 330 340 350 360
pF1KB6 LEEI
::::
XP_011 LEEI
>>NP_001273185 (OMIM: 255995,615521) SH3 and cysteine-ri (325 aa)
initn: 2269 init1: 2269 opt: 2269 Z-score: 1515.2 bits: 288.8 E(85289): 1.2e-77
Smith-Waterman score: 2269; 100.0% identity (100.0% similar) in 325 aa overlap (40-364:1-325)
10 20 30 40 50 60
pF1KB6 PKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQANGEAVGAGGGPIYYIYEEEEE
::::::::::::::::::::::::::::::
NP_001 MELPPEPQANGEAVGAGGGPIYYIYEEEEE
10 20 30
70 80 90 100 110 120
pF1KB6 EEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHE
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 HCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFETLRTGVIMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFETLRTGVIMAN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB6 KERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQS
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 HYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGER
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 VHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDFLEEI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDFLEEI
280 290 300 310 320
>>NP_001273186 (OMIM: 255995,615521) SH3 and cysteine-ri (178 aa)
initn: 1214 init1: 1214 opt: 1214 Z-score: 823.6 bits: 159.9 E(85289): 3.9e-39
Smith-Waterman score: 1214; 100.0% identity (100.0% similar) in 178 aa overlap (187-364:1-178)
160 170 180 190 200 210
pF1KB6 YSNQQYACVKDLSAANRNDPVFETLRTGVIMANKERKKGQADKKNPVAAMMEEEPESARP
::::::::::::::::::::::::::::::
NP_001 MANKERKKGQADKKNPVAAMMEEEPESARP
10 20 30
220 230 240 250 260 270
pF1KB6 EEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITV
40 50 60 70 80 90
280 290 300 310 320 330
pF1KB6 IDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQ
100 110 120 130 140 150
340 350 360
pF1KB6 KGDEAGGYVKVYTGRKVGLFPTDFLEEI
::::::::::::::::::::::::::::
NP_001 KGDEAGGYVKVYTGRKVGLFPTDFLEEI
160 170
>>XP_016862573 (OMIM: 602317) PREDICTED: SH3 and cystein (215 aa)
initn: 475 init1: 417 opt: 431 Z-score: 307.1 bits: 64.7 E(85289): 2.3e-10
Smith-Waterman score: 478; 36.0% identity (67.3% similar) in 214 aa overlap (168-364:3-215)
140 150 160 170 180 190
pF1KB6 QRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFETLRTGVIMANKERK----
.. .:. :::.:::: :. .:.. .:
XP_016 MPIACGNKVDPVYETLRFGTSLAQRTKKGSSG
10 20 30
200 210 220 230 240
pF1KB6 KGQADKKNPVAAMMEEEPESARPEEGK-------------PQDGNPEGDKKAEKKTPDDK
.:. . . .. . : :: : : :..:. . :.. . . .
XP_016 SGSDSPHRTSTSDLVEVPEEANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGS
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB6 HKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNF
.. .:.. : ::::.: :..::.. ::. ::...::::.::.::: ...:::: ::
XP_016 LSKDPLQMNTY-VALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANF
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB6 IIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDF
. :.. .:.. : .:.:.: .: ::::::..:: :.. .: :...: .:.: ::.: :
XP_016 VQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDV
160 170 180 190 200 210
pF1KB6 LEEI
::.:
XP_016 LENI
>>XP_016862572 (OMIM: 602317) PREDICTED: SH3 and cystein (334 aa)
initn: 773 init1: 417 opt: 431 Z-score: 304.9 bits: 64.9 E(85289): 3e-10
Smith-Waterman score: 799; 40.6% identity (69.5% similar) in 298 aa overlap (88-364:38-334)
60 70 80 90 100 110
pF1KB6 GPIYYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIV-LNNKF
: : :....:::: ::::: .::: : :
XP_016 VAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFQEYIFKKPTFCDVCNHMIVGTNAKH
10 20 30 40 50 60
120 130 140 150 160 170
pF1KB6 GLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKD---LSAANR
::::: :: .::..: . . :::.::.: ::.: ::::: ..:..:.:. .. .:.
XP_016 GLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNK
70 80 90 100 110 120
180 190 200 210 220
pF1KB6 NDPVFETLRTGVIMANKERK----KGQADKKNPVAAMMEEEPESARPEEGK---------
:::.:::: :. .:.. .: .:. . . .. . : :: : :
XP_016 VDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEVPEEANGPGGGYDLRKRSNS
130 140 150 160 170 180
230 240 250 260 270
pF1KB6 ----PQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITV
:..:. . :.. . . . .. .:.. : ::::.: :..::.. ::. ::.
XP_016 VFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTY-VALYKFVPQENEDLEMRPGDIITL
190 200 210 220 230 240
280 290 300 310 320 330
pF1KB6 IDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQ
..::::.::.::: ...:::: ::. :.. .:.. : .:.:.: .: ::::::..:: :.
XP_016 LEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVS
250 260 270 280 290 300
340 350 360
pF1KB6 KGDEAGGYVKVYTGRKVGLFPTDFLEEI
. .: :...: .:.: ::.: : ::.:
XP_016 SEEEQDGFIRVLSGKKKGLIPLDVLENI
310 320 330
>>XP_011532340 (OMIM: 602317) PREDICTED: SH3 and cystein (334 aa)
initn: 773 init1: 417 opt: 431 Z-score: 304.9 bits: 64.9 E(85289): 3e-10
Smith-Waterman score: 799; 40.6% identity (69.5% similar) in 298 aa overlap (88-364:38-334)
60 70 80 90 100 110
pF1KB6 GPIYYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIV-LNNKF
: : :....:::: ::::: .::: : :
XP_011 VAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFQEYIFKKPTFCDVCNHMIVGTNAKH
10 20 30 40 50 60
120 130 140 150 160 170
pF1KB6 GLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKD---LSAANR
::::: :: .::..: . . :::.::.: ::.: ::::: ..:..:.:. .. .:.
XP_011 GLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNK
70 80 90 100 110 120
180 190 200 210 220
pF1KB6 NDPVFETLRTGVIMANKERK----KGQADKKNPVAAMMEEEPESARPEEGK---------
:::.:::: :. .:.. .: .:. . . .. . : :: : :
XP_011 VDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEVPEEANGPGGGYDLRKRSNS
130 140 150 160 170 180
230 240 250 260 270
pF1KB6 ----PQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITV
:..:. . :.. . . . .. .:.. : ::::.: :..::.. ::. ::.
XP_011 VFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTY-VALYKFVPQENEDLEMRPGDIITL
190 200 210 220 230 240
280 290 300 310 320 330
pF1KB6 IDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQ
..::::.::.::: ...:::: ::. :.. .:.. : .:.:.: .: ::::::..:: :.
XP_011 LEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVS
250 260 270 280 290 300
340 350 360
pF1KB6 KGDEAGGYVKVYTGRKVGLFPTDFLEEI
. .: :...: .:.: ::.: : ::.:
XP_011 SEEEQDGFIRVLSGKKKGLIPLDVLENI
310 320 330
>>NP_001278978 (OMIM: 602317) SH3 and cysteine-rich doma (341 aa)
initn: 581 init1: 417 opt: 431 Z-score: 304.8 bits: 64.9 E(85289): 3.1e-10
Smith-Waterman score: 490; 28.9% identity (52.8% similar) in 388 aa overlap (4-364:17-341)
10 20 30 40
pF1KB6 MTEKEVLESPKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQ
::.. . .: :: : .: ..:..: :. : :: .. .
NP_001 MIPPSSPREDGVDGLPKEAVGAEQPPSPAST-SSQESKLQKLKRSLSFKTKSLR----SK
10 20 30 40 50
50 60 70 80 90
pF1KB6 ANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEPPKLVND----------KPHKFKDHFF
. . .. . . . : : : : .:.. : : :....:
NP_001 SADNFFQRTNSEDMKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFQEYIF
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB6 KKPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLY
::: ::::: .:::
NP_001 KKPTFCDVCNHMIV----------------------------------------------
120
160 170 180 190 200 210
pF1KB6 SNQQYACVKDLSAANRNDPVFETLRTGVIMANKERK----KGQADKKNPVAAMMEEEPES
:: .:. :::.:::: :. .:.. .: .:. . . .. . : ::
NP_001 -----AC------GNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEVPEE
130 140 150 160 170
220 230 240 250 260
pF1KB6 ARPEEGK-------------PQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKA
: : :..:. . :.. . . . .. .:.. : ::::.:
NP_001 ANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTY-VALYKFVP
180 190 200 210 220 230
270 280 290 300 310 320
pF1KB6 LEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGN
:..::.. ::. ::...::::.::.::: ...:::: ::. :.. .:.. : .:.:.:
NP_001 QENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFIGC
240 250 260 270 280 290
330 340 350 360
pF1KB6 REIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDFLEEI
.: ::::::..:: :.. .: :...: .:.: ::.: : ::.:
NP_001 KEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDVLENI
300 310 320 330 340
>>XP_011532339 (OMIM: 602317) PREDICTED: SH3 and cystein (391 aa)
initn: 773 init1: 417 opt: 431 Z-score: 304.1 bits: 65.0 E(85289): 3.3e-10
Smith-Waterman score: 799; 40.6% identity (69.5% similar) in 298 aa overlap (88-364:95-391)
60 70 80 90 100 110
pF1KB6 GPIYYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIV-LNNKF
: : :....:::: ::::: .::: : :
XP_011 VAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFQEYIFKKPTFCDVCNHMIVGTNAKH
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 GLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKD---LSAANR
::::: :: .::..: . . :::.::.: ::.: ::::: ..:..:.:. .. .:.
XP_011 GLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNK
130 140 150 160 170 180
180 190 200 210 220
pF1KB6 NDPVFETLRTGVIMANKERK----KGQADKKNPVAAMMEEEPESARPEEGK---------
:::.:::: :. .:.. .: .:. . . .. . : :: : :
XP_011 VDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEVPEEANGPGGGYDLRKRSNS
190 200 210 220 230 240
230 240 250 260 270
pF1KB6 ----PQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITV
:..:. . :.. . . . .. .:.. : ::::.: :..::.. ::. ::.
XP_011 VFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTY-VALYKFVPQENEDLEMRPGDIITL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB6 IDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQ
..::::.::.::: ...:::: ::. :.. .:.. : .:.:.: .: ::::::..:: :.
XP_011 LEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVS
310 320 330 340 350 360
340 350 360
pF1KB6 KGDEAGGYVKVYTGRKVGLFPTDFLEEI
. .: :...: .:.: ::.: : ::.:
XP_011 SEEEQDGFIRVLSGKKKGLIPLDVLENI
370 380 390
>>NP_003140 (OMIM: 602317) SH3 and cysteine-rich domain- (402 aa)
initn: 773 init1: 417 opt: 431 Z-score: 304.0 bits: 65.0 E(85289): 3.4e-10
Smith-Waterman score: 809; 35.5% identity (63.3% similar) in 392 aa overlap (4-364:17-402)
10 20 30 40
pF1KB6 MTEKEVLESPKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQ
::.. . .: :: : .: ..:..: :. : :: .. .
NP_003 MIPPSSPREDGVDGLPKEAVGAEQPPSPAST-SSQESKLQKLKRSLSFKTKSLR----SK
10 20 30 40 50
50 60 70 80 90
pF1KB6 ANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEPPKLVND----------KPHKFKDHFF
. . .. . . . : : : : .:.. : : :....:
NP_003 SADNFFQRTNSEDMKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFQEYIF
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB6 KKPKFCDVCARMIV-LNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPL
::: ::::: .::: : : ::::: :: .::..: . . :::.::.: ::.: :::::
NP_003 KKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPL
120 130 140 150 160 170
160 170 180 190 200
pF1KB6 YSNQQYACVKD---LSAANRNDPVFETLRTGVIMANKERK----KGQADKKNPVAAMMEE
..:..:.:. .. .:. :::.:::: :. .:.. .: .:. . . .. . :
NP_003 LIHEQFGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVE
180 190 200 210 220 230
210 220 230 240 250
pF1KB6 EPESARPEEGK-------------PQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALY
:: : : :..:. . :.. . . . .. .:.. : ::::
NP_003 VPEEANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTY-VALY
240 250 260 270 280 290
260 270 280 290 300 310
pF1KB6 RFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRS
.: :..::.. ::. ::...::::.::.::: ...:::: ::. :.. .:.. : .:.
NP_003 KFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRT
300 310 320 330 340 350
320 330 340 350 360
pF1KB6 FVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDFLEEI
:.: .: ::::::..:: :.. .: :...: .:.: ::.: : ::.:
NP_003 FIGCKEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDVLENI
360 370 380 390 400
364 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:53:55 2016 done: Sat Nov 5 16:53:56 2016
Total Scan time: 9.010 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]