Result of FASTA (omim) for
pFN21AB0441
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0441, 444 aa
1>>>pF1KB0441 444 - 444 aa - 444 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5498+/-0.000427; mu= 15.9506+/- 0.026
mean_var=63.9686+/-12.692, 0's: 0 Z-trim(110.3): 28 B-trim: 0 in 0/50
Lambda= 0.160358
statistics sampled from 18557 (18579) to 18557 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.583), E-opt: 0.2 (0.218), width: 16
Scan time: 6.590
The best scores are: opt bits E(85289)
XP_016880447 (OMIM: 182144) PREDICTED: serine hydr ( 444) 2950 691.6 1.1e-198
NP_683718 (OMIM: 182144) serine hydroxymethyltrans ( 444) 2950 691.6 1.1e-198
XP_016880448 (OMIM: 182144) PREDICTED: serine hydr ( 306) 2016 475.4 8.7e-134
NP_004160 (OMIM: 182144) serine hydroxymethyltrans ( 483) 1846 436.2 9.1e-122
XP_005256824 (OMIM: 182144) PREDICTED: serine hydr ( 483) 1846 436.2 9.1e-122
XP_016880446 (OMIM: 182144) PREDICTED: serine hydr ( 483) 1846 436.2 9.1e-122
XP_011522294 (OMIM: 182144) PREDICTED: serine hydr ( 403) 1841 435.0 1.7e-121
NP_001159829 (OMIM: 138450) serine hydroxymethyltr ( 483) 1256 299.7 1.1e-80
NP_001159830 (OMIM: 138450) serine hydroxymethyltr ( 483) 1256 299.7 1.1e-80
NP_001159831 (OMIM: 138450) serine hydroxymethyltr ( 483) 1256 299.7 1.1e-80
NP_005403 (OMIM: 138450) serine hydroxymethyltrans ( 504) 1256 299.7 1.2e-80
NP_001268715 (OMIM: 182144) serine hydroxymethyltr ( 345) 1117 267.5 4e-71
XP_016880449 (OMIM: 182144) PREDICTED: serine hydr ( 265) 907 218.9 1.3e-56
NP_001159828 (OMIM: 138450) serine hydroxymethyltr ( 494) 804 195.1 3.4e-49
XP_011536977 (OMIM: 138450) PREDICTED: serine hydr ( 408) 589 145.4 2.7e-34
XP_011536980 (OMIM: 138450) PREDICTED: serine hydr ( 408) 589 145.4 2.7e-34
XP_011536979 (OMIM: 138450) PREDICTED: serine hydr ( 408) 589 145.4 2.7e-34
XP_011536978 (OMIM: 138450) PREDICTED: serine hydr ( 408) 589 145.4 2.7e-34
>>XP_016880447 (OMIM: 182144) PREDICTED: serine hydroxym (444 aa)
initn: 2950 init1: 2950 opt: 2950 Z-score: 3688.0 bits: 691.6 E(85289): 1.1e-198
Smith-Waterman score: 2950; 100.0% identity (100.0% similar) in 444 aa overlap (1-444:1-444)
10 20 30 40 50 60
pF1KB0 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVAVALKQAMTLEFKVYQHQVVANCRALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVAVALKQAMTLEFKVYQHQVVANCRALS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 EALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 GLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQA
370 380 390 400 410 420
430 440
pF1KB0 AVQALREEVESFASLFPLPGLPDF
::::::::::::::::::::::::
XP_016 AVQALREEVESFASLFPLPGLPDF
430 440
>>NP_683718 (OMIM: 182144) serine hydroxymethyltransfera (444 aa)
initn: 2950 init1: 2950 opt: 2950 Z-score: 3688.0 bits: 691.6 E(85289): 1.1e-198
Smith-Waterman score: 2950; 100.0% identity (100.0% similar) in 444 aa overlap (1-444:1-444)
10 20 30 40 50 60
pF1KB0 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVAVALKQAMTLEFKVYQHQVVANCRALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVAVALKQAMTLEFKVYQHQVVANCRALS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 EALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 EALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 GLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 GLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQA
370 380 390 400 410 420
430 440
pF1KB0 AVQALREEVESFASLFPLPGLPDF
::::::::::::::::::::::::
NP_683 AVQALREEVESFASLFPLPGLPDF
430 440
>>XP_016880448 (OMIM: 182144) PREDICTED: serine hydroxym (306 aa)
initn: 2016 init1: 2016 opt: 2016 Z-score: 2522.8 bits: 475.4 E(85289): 8.7e-134
Smith-Waterman score: 2016; 100.0% identity (100.0% similar) in 306 aa overlap (139-444:1-306)
110 120 130 140 150 160
pF1KB0 QCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFE
::::::::::::::::::::::::::::::
XP_016 MGLDLPDGGHLTHGFMTDKKKISATSIFFE
10 20 30
170 180 190 200 210 220
pF1KB0 SMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMAD
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB0 MAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVAVALKQAMTLEFKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVAVALKQAMTLEFKVY
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB0 QHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKN
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB0 TCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKE
220 230 240 250 260 270
410 420 430 440
pF1KB0 FKERLAGDKYQAAVQALREEVESFASLFPLPGLPDF
::::::::::::::::::::::::::::::::::::
XP_016 FKERLAGDKYQAAVQALREEVESFASLFPLPGLPDF
280 290 300
>>NP_004160 (OMIM: 182144) serine hydroxymethyltransfera (483 aa)
initn: 1846 init1: 1846 opt: 1846 Z-score: 2307.1 bits: 436.2 E(85289): 9.1e-122
Smith-Waterman score: 2808; 91.8% identity (91.8% similar) in 476 aa overlap (1-437:1-476)
10 20 30 40 50 60
pF1KB0 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
190 200 210 220 230 240
250 260 270
pF1KB0 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGV---------------------------
:::::::::::::::::::::::::::::::::
NP_004 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGL
250 260 270 280 290 300
280 290 300 310 320
pF1KB0 ------------AVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLIL
::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLIL
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB0 VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQK
370 380 390 400 410 420
390 400 410 420 430 440
pF1KB0 VAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL
430 440 450 460 470 480
pF1KB0 PDF
NP_004 PDF
>>XP_005256824 (OMIM: 182144) PREDICTED: serine hydroxym (483 aa)
initn: 1846 init1: 1846 opt: 1846 Z-score: 2307.1 bits: 436.2 E(85289): 9.1e-122
Smith-Waterman score: 2808; 91.8% identity (91.8% similar) in 476 aa overlap (1-437:1-476)
10 20 30 40 50 60
pF1KB0 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
190 200 210 220 230 240
250 260 270
pF1KB0 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGV---------------------------
:::::::::::::::::::::::::::::::::
XP_005 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGL
250 260 270 280 290 300
280 290 300 310 320
pF1KB0 ------------AVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLIL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLIL
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB0 VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQK
370 380 390 400 410 420
390 400 410 420 430 440
pF1KB0 VAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL
430 440 450 460 470 480
pF1KB0 PDF
XP_005 PDF
>>XP_016880446 (OMIM: 182144) PREDICTED: serine hydroxym (483 aa)
initn: 1846 init1: 1846 opt: 1846 Z-score: 2307.1 bits: 436.2 E(85289): 9.1e-122
Smith-Waterman score: 2808; 91.8% identity (91.8% similar) in 476 aa overlap (1-437:1-476)
10 20 30 40 50 60
pF1KB0 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
190 200 210 220 230 240
250 260 270
pF1KB0 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGV---------------------------
:::::::::::::::::::::::::::::::::
XP_016 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGL
250 260 270 280 290 300
280 290 300 310 320
pF1KB0 ------------AVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLIL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLIL
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB0 VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQK
370 380 390 400 410 420
390 400 410 420 430 440
pF1KB0 VAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL
430 440 450 460 470 480
pF1KB0 PDF
XP_016 PDF
>>XP_011522294 (OMIM: 182144) PREDICTED: serine hydroxym (403 aa)
initn: 1841 init1: 1841 opt: 1841 Z-score: 2302.1 bits: 435.0 E(85289): 1.7e-121
Smith-Waterman score: 2607; 90.8% identity (90.8% similar) in 444 aa overlap (1-444:1-403)
10 20 30 40 50 60
pF1KB0 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVAVALKQAMTLEFKVYQHQVVANCRALS
::::::::::::::::::::::::::::::::
XP_011 VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKG----------------------------
250 260 270
310 320 330 340 350 360
pF1KB0 EALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPS
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 -------------GSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPS
280 290 300 310
370 380 390 400 410 420
pF1KB0 GLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQA
320 330 340 350 360 370
430 440
pF1KB0 AVQALREEVESFASLFPLPGLPDF
::::::::::::::::::::::::
XP_011 AVQALREEVESFASLFPLPGLPDF
380 390 400
>>NP_001159829 (OMIM: 138450) serine hydroxymethyltransf (483 aa)
initn: 1816 init1: 1256 opt: 1256 Z-score: 1569.4 bits: 299.7 E(85289): 1.1e-80
Smith-Waterman score: 1742; 60.1% identity (77.6% similar) in 456 aa overlap (24-439:26-478)
10 20 30 40 50
pF1KB0 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFAS
. :.::: :.......:..:: :::::::::: :
NP_001 MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB0 RAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPY
::.::::::::::::::::::.:::::.: .::.: :::.:::.:. ::: ::::::::
NP_001 RAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB0 SGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDT
::::::.::::::..:: ::::::::::::::::.:.: :.::::::::::::::.:: :
NP_001 SGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKT
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB0 GYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAA
: :.:.:: .::::.:.::::::: :.: ..:::.:.. :: :.:.::::::::::::
NP_001 GLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAA
190 200 210 220 230 240
240 250 260 270
pF1KB0 GVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGV-------------------------
:.::::.: .::::::::::: :.:.:::::::
NP_001 KVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFP
250 260 270 280 290 300
280 290 300 310
pF1KB0 --------------AVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHL
::::::: : :. :. ::. : ::...:: : ::..:.::.::::
NP_001 SLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHL
310 320 330 340 350 360
320 330 340 350 360 370
pF1KB0 ILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDF
.::::: :: ::.:::.::: ::. :::::::::::. :.:::::.:::::: . : ::
NP_001 VLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDF
370 380 390 400 410 420
380 390 400 410 420 430
pF1KB0 QKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQA-LREEVESFASLFPL
..:. :: .:... :...: : : :..:: : :. . : ::..::.:: ::.
NP_001 RRVVDFIDEGVNIGLEVKSKT---AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPM
430 440 450 460 470
440
pF1KB0 PGLPDF
:
NP_001 PGFDEH
480
>>NP_001159830 (OMIM: 138450) serine hydroxymethyltransf (483 aa)
initn: 1816 init1: 1256 opt: 1256 Z-score: 1569.4 bits: 299.7 E(85289): 1.1e-80
Smith-Waterman score: 1742; 60.1% identity (77.6% similar) in 456 aa overlap (24-439:26-478)
10 20 30 40 50
pF1KB0 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFAS
. :.::: :.......:..:: :::::::::: :
NP_001 MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB0 RAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPY
::.::::::::::::::::::.:::::.: .::.: :::.:::.:. ::: ::::::::
NP_001 RAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB0 SGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDT
::::::.::::::..:: ::::::::::::::::.:.: :.::::::::::::::.:: :
NP_001 SGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKT
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB0 GYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAA
: :.:.:: .::::.:.::::::: :.: ..:::.:.. :: :.:.::::::::::::
NP_001 GLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAA
190 200 210 220 230 240
240 250 260 270
pF1KB0 GVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGV-------------------------
:.::::.: .::::::::::: :.:.:::::::
NP_001 KVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFP
250 260 270 280 290 300
280 290 300 310
pF1KB0 --------------AVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHL
::::::: : :. :. ::. : ::...:: : ::..:.::.::::
NP_001 SLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHL
310 320 330 340 350 360
320 330 340 350 360 370
pF1KB0 ILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDF
.::::: :: ::.:::.::: ::. :::::::::::. :.:::::.:::::: . : ::
NP_001 VLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDF
370 380 390 400 410 420
380 390 400 410 420 430
pF1KB0 QKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQA-LREEVESFASLFPL
..:. :: .:... :...: : : :..:: : :. . : ::..::.:: ::.
NP_001 RRVVDFIDEGVNIGLEVKSKT---AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPM
430 440 450 460 470
440
pF1KB0 PGLPDF
:
NP_001 PGFDEH
480
>>NP_001159831 (OMIM: 138450) serine hydroxymethyltransf (483 aa)
initn: 1816 init1: 1256 opt: 1256 Z-score: 1569.4 bits: 299.7 E(85289): 1.1e-80
Smith-Waterman score: 1742; 60.1% identity (77.6% similar) in 456 aa overlap (24-439:26-478)
10 20 30 40 50
pF1KB0 MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFAS
. :.::: :.......:..:: :::::::::: :
NP_001 MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB0 RAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPY
::.::::::::::::::::::.:::::.: .::.: :::.:::.:. ::: ::::::::
NP_001 RAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB0 SGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDT
::::::.::::::..:: ::::::::::::::::.:.: :.::::::::::::::.:: :
NP_001 SGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKT
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB0 GYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAA
: :.:.:: .::::.:.::::::: :.: ..:::.:.. :: :.:.::::::::::::
NP_001 GLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAA
190 200 210 220 230 240
240 250 260 270
pF1KB0 GVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGV-------------------------
:.::::.: .::::::::::: :.:.:::::::
NP_001 KVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFP
250 260 270 280 290 300
280 290 300 310
pF1KB0 --------------AVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHL
::::::: : :. :. ::. : ::...:: : ::..:.::.::::
NP_001 SLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHL
310 320 330 340 350 360
320 330 340 350 360 370
pF1KB0 ILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDF
.::::: :: ::.:::.::: ::. :::::::::::. :.:::::.:::::: . : ::
NP_001 VLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDF
370 380 390 400 410 420
380 390 400 410 420 430
pF1KB0 QKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQA-LREEVESFASLFPL
..:. :: .:... :...: : : :..:: : :. . : ::..::.:: ::.
NP_001 RRVVDFIDEGVNIGLEVKSKT---AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPM
430 440 450 460 470
440
pF1KB0 PGLPDF
:
NP_001 PGFDEH
480
444 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:52:38 2016 done: Sat Nov 5 16:52:39 2016
Total Scan time: 6.590 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]