Result of FASTA (omim) for
pFN21AB8528
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8528, 885 aa
1>>>pF1KB8528 885 - 885 aa - 885 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7526+/-0.00043; mu= 15.3148+/- 0.027
mean_var=123.9535+/-25.151, 0's: 0 Z-trim(115.1): 20 B-trim: 1208 in 1/49
Lambda= 0.115198
statistics sampled from 25278 (25296) to 25278 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.653), E-opt: 0.2 (0.297), width: 16
Scan time: 13.290
The best scores are: opt bits E(85289)
NP_001001998 (OMIM: 605960) exosome component 10 i ( 885) 5937 998.7 0
XP_005263532 (OMIM: 605960) PREDICTED: exosome com ( 890) 5917 995.4 0
NP_002676 (OMIM: 605960) exosome component 10 isof ( 860) 4739 799.6 0
XP_016856984 (OMIM: 605960) PREDICTED: exosome com ( 469) 3064 521.0 5.1e-147
XP_016856983 (OMIM: 605960) PREDICTED: exosome com ( 474) 3044 517.7 5.1e-146
XP_016856986 (OMIM: 605960) PREDICTED: exosome com ( 453) 3026 514.7 3.9e-145
XP_016856985 (OMIM: 605960) PREDICTED: exosome com ( 458) 3006 511.4 4e-144
>>NP_001001998 (OMIM: 605960) exosome component 10 isofo (885 aa)
initn: 5937 init1: 5937 opt: 5937 Z-score: 5337.1 bits: 998.7 E(85289): 0
Smith-Waterman score: 5937; 100.0% identity (100.0% similar) in 885 aa overlap (1-885:1-885)
10 20 30 40 50 60
pF1KB8 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF
790 800 810 820 830 840
850 860 870 880
pF1KB8 DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR
850 860 870 880
>>XP_005263532 (OMIM: 605960) PREDICTED: exosome compone (890 aa)
initn: 5923 init1: 5026 opt: 5917 Z-score: 5319.2 bits: 995.4 E(85289): 0
Smith-Waterman score: 5917; 99.4% identity (99.4% similar) in 890 aa overlap (1-885:1-890)
10 20 30 40 50 60
pF1KB8 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEI
670 680 690 700 710 720
730 740 750 760 770
pF1KB8 SNRWKLAQVQVQKDSKEAVKKKAAEQT-----AAREQAKEACKAAAEQAISVRQQVVLEN
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
XP_005 SNRWKLAQVQVQKDSKEAVKKKAAEQTVLSLAAAREQAKEACKAAAEQAISVRQQVVLEN
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB8 AAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSK
790 800 810 820 830 840
840 850 860 870 880
pF1KB8 VSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR
850 860 870 880 890
>>NP_002676 (OMIM: 605960) exosome component 10 isoform (860 aa)
initn: 5756 init1: 4686 opt: 4739 Z-score: 4261.3 bits: 799.6 E(85289): 0
Smith-Waterman score: 5710; 97.2% identity (97.2% similar) in 885 aa overlap (1-885:1-860)
10 20 30 40 50 60
pF1KB8 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEI
:::::::::::::::::::::::::::::::::: :
NP_002 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRM-------------------------I
670 680 690
730 740 750 760 770 780
pF1KB8 SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR
700 710 720 730 740 750
790 800 810 820 830 840
pF1KB8 ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF
760 770 780 790 800 810
850 860 870 880
pF1KB8 DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR
:::::::::::::::::::::::::::::::::::::::::::::
NP_002 DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR
820 830 840 850 860
>>XP_016856984 (OMIM: 605960) PREDICTED: exosome compone (469 aa)
initn: 3064 init1: 3064 opt: 3064 Z-score: 2760.5 bits: 521.0 E(85289): 5.1e-147
Smith-Waterman score: 3064; 99.6% identity (99.8% similar) in 460 aa overlap (426-885:10-469)
400 410 420 430 440 450
pF1KB8 LNLGRHSLDHLLKLYCNVDSNKQYQLADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEM
. ::::::::::::::::::::::::::::
XP_016 MRASQTQPSLSPLPEEMLSYARDDTHYLLYIYDKMRLEM
10 20 30
460 470 480 490 500 510
pF1KB8 WERGNGQPVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WERGNGQPVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFA
40 50 60 70 80 90
520 530 540 550 560 570
pF1KB8 WRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQ
100 110 120 130 140 150
580 590 600 610 620 630
pF1KB8 AREMPLLKSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AREMPLLKSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQA
160 170 180 190 200 210
640 650 660 670 680 690
pF1KB8 SLFPDEKEDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLFPDEKEDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMF
220 230 240 250 260 270
700 710 720 730 740 750
pF1KB8 LPSLGHRAPVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPSLGHRAPVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKE
280 290 300 310 320 330
760 770 780 790 800 810
pF1KB8 ACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEF
340 350 360 370 380 390
820 830 840 850 860 870
pF1KB8 TPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSD
400 410 420 430 440 450
880
pF1KB8 RGFRYNWPQR
::::::::::
XP_016 RGFRYNWPQR
460
>>XP_016856983 (OMIM: 605960) PREDICTED: exosome compone (474 aa)
initn: 3050 init1: 2153 opt: 3044 Z-score: 2742.5 bits: 517.7 E(85289): 5.1e-146
Smith-Waterman score: 3044; 98.5% identity (98.7% similar) in 465 aa overlap (426-885:10-474)
400 410 420 430 440 450
pF1KB8 LNLGRHSLDHLLKLYCNVDSNKQYQLADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEM
. ::::::::::::::::::::::::::::
XP_016 MRASQTQPSLSPLPEEMLSYARDDTHYLLYIYDKMRLEM
10 20 30
460 470 480 490 500 510
pF1KB8 WERGNGQPVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WERGNGQPVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFA
40 50 60 70 80 90
520 530 540 550 560 570
pF1KB8 WRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQ
100 110 120 130 140 150
580 590 600 610 620 630
pF1KB8 AREMPLLKSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AREMPLLKSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQA
160 170 180 190 200 210
640 650 660 670 680 690
pF1KB8 SLFPDEKEDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLFPDEKEDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMF
220 230 240 250 260 270
700 710 720 730 740 750
pF1KB8 LPSLGHRAPVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQT-----AAR
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_016 LPSLGHRAPVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTVLSLAAAR
280 290 300 310 320 330
760 770 780 790 800 810
pF1KB8 EQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEP
340 350 360 370 380 390
820 830 840 850 860 870
pF1KB8 PEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFP
400 410 420 430 440 450
880
pF1KB8 TGKSDRGFRYNWPQR
:::::::::::::::
XP_016 TGKSDRGFRYNWPQR
460 470
>>XP_016856986 (OMIM: 605960) PREDICTED: exosome compone (453 aa)
initn: 3026 init1: 3026 opt: 3026 Z-score: 2726.6 bits: 514.7 E(85289): 3.9e-145
Smith-Waterman score: 3026; 100.0% identity (100.0% similar) in 453 aa overlap (433-885:1-453)
410 420 430 440 450 460
pF1KB8 LDHLLKLYCNVDSNKQYQLADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQ
::::::::::::::::::::::::::::::
XP_016 MLSYARDDTHYLLYIYDKMRLEMWERGNGQ
10 20 30
470 480 490 500 510 520
pF1KB8 PVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTAR
40 50 60 70 80 90
530 540 550 560 570 580
pF1KB8 REDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLL
100 110 120 130 140 150
590 600 610 620 630 640
pF1KB8 KSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEK
160 170 180 190 200 210
650 660 670 680 690 700
pF1KB8 EDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHR
220 230 240 250 260 270
710 720 730 740 750 760
pF1KB8 APVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAE
280 290 300 310 320 330
770 780 790 800 810 820
pF1KB8 QAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQ
340 350 360 370 380 390
830 840 850 860 870 880
pF1KB8 SDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNW
400 410 420 430 440 450
pF1KB8 PQR
:::
XP_016 PQR
>>XP_016856985 (OMIM: 605960) PREDICTED: exosome compone (458 aa)
initn: 3012 init1: 2115 opt: 3006 Z-score: 2708.5 bits: 511.4 E(85289): 4e-144
Smith-Waterman score: 3006; 98.9% identity (98.9% similar) in 458 aa overlap (433-885:1-458)
410 420 430 440 450 460
pF1KB8 LDHLLKLYCNVDSNKQYQLADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQ
::::::::::::::::::::::::::::::
XP_016 MLSYARDDTHYLLYIYDKMRLEMWERGNGQ
10 20 30
470 480 490 500 510 520
pF1KB8 PVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTAR
40 50 60 70 80 90
530 540 550 560 570 580
pF1KB8 REDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLL
100 110 120 130 140 150
590 600 610 620 630 640
pF1KB8 KSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEK
160 170 180 190 200 210
650 660 670 680 690 700
pF1KB8 EDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHR
220 230 240 250 260 270
710 720 730 740 750
pF1KB8 APVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQT-----AAREQAKEAC
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 APVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTVLSLAAAREQAKEAC
280 290 300 310 320 330
760 770 780 790 800 810
pF1KB8 KAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTP
340 350 360 370 380 390
820 830 840 850 860 870
pF1KB8 YDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRG
400 410 420 430 440 450
880
pF1KB8 FRYNWPQR
::::::::
XP_016 FRYNWPQR
885 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:35:36 2016 done: Sat Nov 5 16:35:38 2016
Total Scan time: 13.290 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]