Result of FASTA (omim) for
pFN21AB8474
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8474, 841 aa
1>>>pF1KB8474 841 - 841 aa - 841 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.2294+/-0.000607; mu= -20.5878+/- 0.037
mean_var=688.8393+/-148.391, 0's: 0 Z-trim(120.7): 427 B-trim: 1246 in 1/55
Lambda= 0.048867
statistics sampled from 35750 (36224) to 35750 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.425), width: 16
Scan time: 16.820
The best scores are: opt bits E(85289)
NP_064522 (OMIM: 300408) GRIP1-associated protein ( 841) 5287 388.9 5e-107
XP_016885148 (OMIM: 300408) PREDICTED: GRIP1-assoc ( 765) 4817 355.8 4.4e-97
XP_016885147 (OMIM: 300408) PREDICTED: GRIP1-assoc ( 765) 4817 355.8 4.4e-97
XP_016885145 (OMIM: 300408) PREDICTED: GRIP1-assoc ( 815) 3361 253.1 3.7e-66
XP_016885149 (OMIM: 300408) PREDICTED: GRIP1-assoc ( 739) 2905 220.9 1.6e-56
XP_016885150 (OMIM: 300408) PREDICTED: GRIP1-assoc ( 739) 2905 220.9 1.6e-56
XP_011542237 (OMIM: 300408) PREDICTED: GRIP1-assoc ( 851) 2830 215.7 7.1e-55
XP_016885146 (OMIM: 300408) PREDICTED: GRIP1-assoc ( 775) 2795 213.2 3.7e-54
XP_011542239 (OMIM: 300408) PREDICTED: GRIP1-assoc ( 775) 2795 213.2 3.7e-54
XP_011542238 (OMIM: 300408) PREDICTED: GRIP1-assoc ( 825) 2724 208.2 1.2e-52
XP_006716651 (OMIM: 131950,226670,226730,601282,61 (4579) 425 46.9 0.0025
XP_011533096 (OMIM: 602581) PREDICTED: golgin subf ( 850) 381 43.1 0.0066
XP_005266224 (OMIM: 602581) PREDICTED: golgin subf (1307) 381 43.2 0.009
XP_011533095 (OMIM: 602581) PREDICTED: golgin subf (1407) 381 43.3 0.0094
XP_005266221 (OMIM: 602581) PREDICTED: golgin subf (1458) 381 43.3 0.0097
XP_006719799 (OMIM: 602581) PREDICTED: golgin subf (1498) 381 43.3 0.0099
XP_006719800 (OMIM: 602581) PREDICTED: golgin subf (1498) 381 43.3 0.0099
NP_005886 (OMIM: 602581) golgin subfamily A member (1498) 381 43.3 0.0099
>>NP_064522 (OMIM: 300408) GRIP1-associated protein 1 [H (841 aa)
initn: 5287 init1: 5287 opt: 5287 Z-score: 2042.4 bits: 388.9 E(85289): 5e-107
Smith-Waterman score: 5287; 100.0% identity (100.0% similar) in 841 aa overlap (1-841:1-841)
10 20 30 40 50 60
pF1KB8 MAQALSEEEFQRMQAQLLELRTNNYQLSDELRKNGVELTSLRQKVAYLDKEFSKAQKALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MAQALSEEEFQRMQAQLLELRTNNYQLSDELRKNGVELTSLRQKVAYLDKEFSKAQKALS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KSKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQMEQLEQENQQLKEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 KSKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQMEQLEQENQQLKEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFSAVSEGQGDPPGGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 AAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFSAVSEGQGDPPGGPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 PTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELEAANQSLAELRDQRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 SFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELEAANQSLAELRDQRQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 GERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 EQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 EQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 EARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVRARYERELRELHEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 EARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVRARYERELRELHEDK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 KRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFERRLKEAEESLQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 KRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFERRLKEAEESLQQQQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 QEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTISSLKQEVKDTVDGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 QEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTISSLKQEVKDTVDGQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 RILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLEELVLSEMNSPSRTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 RILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLEELVLSEMNSPSRTQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 TGDSSSISSFSYREILREKESSAVPARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 TGDSSSISSFSYREILREKESSAVPARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 EKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAGHTDRSGLGSVLRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 EKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAGHTDRSGLGSVLRDL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 VKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKECVGPPDPDLEPGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 VKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKECVGPPDPDLEPGET
790 800 810 820 830 840
pF1KB8 S
:
NP_064 S
>>XP_016885148 (OMIM: 300408) PREDICTED: GRIP1-associate (765 aa)
initn: 4817 init1: 4817 opt: 4817 Z-score: 1863.9 bits: 355.8 E(85289): 4.4e-97
Smith-Waterman score: 4817; 99.9% identity (99.9% similar) in 765 aa overlap (77-841:1-765)
50 60 70 80 90 100
pF1KB8 YLDKEFSKAQKALSKSKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQ
::::::::::::::::::::::::::::::
XP_016 MLQAKLHSQEEDFRLQNSTLMAEFSKLCSQ
10 20 30
110 120 130 140 150 160
pF1KB8 MEQLEQENQQLKEGAAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEQLEQENQQLKEGAAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFS
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB8 AVSEGQGDPPGGPAPTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQE
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVSEGQGDPPGGLAPTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQE
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB8 ELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELE
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB8 AANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALE
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB8 QIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQ
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB8 EIGQEKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIGQEKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVR
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB8 ARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFE
400 410 420 430 440 450
530 540 550 560 570 580
pF1KB8 RRLKEAEESLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRLKEAEESLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTI
460 470 480 490 500 510
590 600 610 620 630 640
pF1KB8 SSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLE
520 530 540 550 560 570
650 660 670 680 690 700
pF1KB8 ELVLSEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLSSSPQAQPPRPAELSDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELVLSEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLSSSPQAQPPRPAELSDE
580 590 600 610 620 630
710 720 730 740 750 760
pF1KB8 EVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAG
640 650 660 670 680 690
770 780 790 800 810 820
pF1KB8 HTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKE
700 710 720 730 740 750
830 840
pF1KB8 CVGPPDPDLEPGETS
:::::::::::::::
XP_016 CVGPPDPDLEPGETS
760
>>XP_016885147 (OMIM: 300408) PREDICTED: GRIP1-associate (765 aa)
initn: 4817 init1: 4817 opt: 4817 Z-score: 1863.9 bits: 355.8 E(85289): 4.4e-97
Smith-Waterman score: 4817; 99.9% identity (99.9% similar) in 765 aa overlap (77-841:1-765)
50 60 70 80 90 100
pF1KB8 YLDKEFSKAQKALSKSKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQ
::::::::::::::::::::::::::::::
XP_016 MLQAKLHSQEEDFRLQNSTLMAEFSKLCSQ
10 20 30
110 120 130 140 150 160
pF1KB8 MEQLEQENQQLKEGAAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEQLEQENQQLKEGAAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFS
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB8 AVSEGQGDPPGGPAPTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQE
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVSEGQGDPPGGLAPTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQE
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB8 ELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELE
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB8 AANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALE
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB8 QIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQ
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB8 EIGQEKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIGQEKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVR
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB8 ARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFE
400 410 420 430 440 450
530 540 550 560 570 580
pF1KB8 RRLKEAEESLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRLKEAEESLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTI
460 470 480 490 500 510
590 600 610 620 630 640
pF1KB8 SSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLE
520 530 540 550 560 570
650 660 670 680 690 700
pF1KB8 ELVLSEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLSSSPQAQPPRPAELSDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELVLSEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLSSSPQAQPPRPAELSDE
580 590 600 610 620 630
710 720 730 740 750 760
pF1KB8 EVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAG
640 650 660 670 680 690
770 780 790 800 810 820
pF1KB8 HTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKE
700 710 720 730 740 750
830 840
pF1KB8 CVGPPDPDLEPGETS
:::::::::::::::
XP_016 CVGPPDPDLEPGETS
760
>>XP_016885145 (OMIM: 300408) PREDICTED: GRIP1-associate (815 aa)
initn: 3316 init1: 3316 opt: 3361 Z-score: 1308.8 bits: 253.1 E(85289): 3.7e-66
Smith-Waterman score: 5042; 96.8% identity (96.8% similar) in 841 aa overlap (1-841:1-815)
10 20 30 40 50 60
pF1KB8 MAQALSEEEFQRMQAQLLELRTNNYQLSDELRKNGVELTSLRQKVAYLDKEFSKAQKALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAQALSEEEFQRMQAQLLELRTNNYQLSDELRKNGVELTSLRQKVAYLDKEFSKAQKALS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KSKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQMEQLEQENQQLKEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQMEQLEQENQQLKEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFSAVSEGQGDPPGGPA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_016 AAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFSAVSEGQGDPPGGLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 PTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELEAANQSLAELRDQRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELEAANQSLAELRDQRQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 EQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 EARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVRARYERELRELHEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVRARYERELRELHEDK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 KRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFERRLKEAEESLQQQQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFERRLKEAE-------
490 500 510 520 530
550 560 570 580 590 600
pF1KB8 QEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTISSLKQEVKDTVDGQ
:::::::::::::::::::::::::::::::::::::::::
XP_016 -------------------GKEEELQDVRDQLEQAQEERDCHLKTISSLKQEVKDTVDGQ
540 550 560 570
610 620 630 640 650 660
pF1KB8 RILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLEELVLSEMNSPSRTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLEELVLSEMNSPSRTQ
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB8 TGDSSSISSFSYREILREKESSAVPARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGDSSSISSFSYREILREKESSAVPARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQ
640 650 660 670 680 690
730 740 750 760 770 780
pF1KB8 EKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAGHTDRSGLGSVLRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAGHTDRSGLGSVLRDL
700 710 720 730 740 750
790 800 810 820 830 840
pF1KB8 VKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKECVGPPDPDLEPGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKECVGPPDPDLEPGET
760 770 780 790 800 810
pF1KB8 S
:
XP_016 S
>>XP_016885149 (OMIM: 300408) PREDICTED: GRIP1-associate (739 aa)
initn: 2860 init1: 2860 opt: 2905 Z-score: 1135.6 bits: 220.9 E(85289): 1.6e-56
Smith-Waterman score: 4586; 96.5% identity (96.5% similar) in 765 aa overlap (77-841:1-739)
50 60 70 80 90 100
pF1KB8 YLDKEFSKAQKALSKSKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQ
::::::::::::::::::::::::::::::
XP_016 MLQAKLHSQEEDFRLQNSTLMAEFSKLCSQ
10 20 30
110 120 130 140 150 160
pF1KB8 MEQLEQENQQLKEGAAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEQLEQENQQLKEGAAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFS
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB8 AVSEGQGDPPGGPAPTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQE
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVSEGQGDPPGGLAPTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQE
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB8 ELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELE
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB8 AANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALE
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB8 QIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQ
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB8 EIGQEKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIGQEKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVR
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB8 ARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFE
400 410 420 430 440 450
530 540 550 560 570 580
pF1KB8 RRLKEAEESLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTI
::::::: :::::::::::::::::::::::::::
XP_016 RRLKEAE--------------------------GKEEELQDVRDQLEQAQEERDCHLKTI
460 470 480
590 600 610 620 630 640
pF1KB8 SSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLE
490 500 510 520 530 540
650 660 670 680 690 700
pF1KB8 ELVLSEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLSSSPQAQPPRPAELSDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELVLSEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLSSSPQAQPPRPAELSDE
550 560 570 580 590 600
710 720 730 740 750 760
pF1KB8 EVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAG
610 620 630 640 650 660
770 780 790 800 810 820
pF1KB8 HTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKE
670 680 690 700 710 720
830 840
pF1KB8 CVGPPDPDLEPGETS
:::::::::::::::
XP_016 CVGPPDPDLEPGETS
730
>>XP_016885150 (OMIM: 300408) PREDICTED: GRIP1-associate (739 aa)
initn: 2860 init1: 2860 opt: 2905 Z-score: 1135.6 bits: 220.9 E(85289): 1.6e-56
Smith-Waterman score: 4586; 96.5% identity (96.5% similar) in 765 aa overlap (77-841:1-739)
50 60 70 80 90 100
pF1KB8 YLDKEFSKAQKALSKSKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQ
::::::::::::::::::::::::::::::
XP_016 MLQAKLHSQEEDFRLQNSTLMAEFSKLCSQ
10 20 30
110 120 130 140 150 160
pF1KB8 MEQLEQENQQLKEGAAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEQLEQENQQLKEGAAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFS
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB8 AVSEGQGDPPGGPAPTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQE
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVSEGQGDPPGGLAPTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQE
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB8 ELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELE
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB8 AANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALE
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB8 QIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQ
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB8 EIGQEKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIGQEKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVR
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB8 ARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFE
400 410 420 430 440 450
530 540 550 560 570 580
pF1KB8 RRLKEAEESLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTI
::::::: :::::::::::::::::::::::::::
XP_016 RRLKEAE--------------------------GKEEELQDVRDQLEQAQEERDCHLKTI
460 470 480
590 600 610 620 630 640
pF1KB8 SSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLE
490 500 510 520 530 540
650 660 670 680 690 700
pF1KB8 ELVLSEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLSSSPQAQPPRPAELSDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELVLSEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLSSSPQAQPPRPAELSDE
550 560 570 580 590 600
710 720 730 740 750 760
pF1KB8 EVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAG
610 620 630 640 650 660
770 780 790 800 810 820
pF1KB8 HTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKE
670 680 690 700 710 720
830 840
pF1KB8 CVGPPDPDLEPGETS
:::::::::::::::
XP_016 CVGPPDPDLEPGETS
730
>>XP_011542237 (OMIM: 300408) PREDICTED: GRIP1-associate (851 aa)
initn: 2685 init1: 2685 opt: 2830 Z-score: 1106.2 bits: 215.7 E(85289): 7.1e-55
Smith-Waterman score: 5243; 98.7% identity (98.7% similar) in 851 aa overlap (1-841:1-851)
10 20 30 40 50 60
pF1KB8 MAQALSEEEFQRMQAQLLELRTNNYQLSDELRKNGVELTSLRQKVAYLDKEFSKAQKALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAQALSEEEFQRMQAQLLELRTNNYQLSDELRKNGVELTSLRQKVAYLDKEFSKAQKALS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KSKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQMEQLEQENQQLKEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQMEQLEQENQQLKEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFSAVSEGQGDPPGGPA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_011 AAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFSAVSEGQGDPPGGLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 PTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELEAANQSLAELRDQRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELEAANQSLAELRDQRQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 EQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQ
370 380 390 400 410 420
430 440 450 460 470
pF1KB8 EARK----------SAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVRARYE
:::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARKEVDCHRPGPQSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVRARYE
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB8 RELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFERRLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFERRLK
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB8 EAEESLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTISSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAEESLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTISSLK
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB8 QEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLEELVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLEELVL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB8 SEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLSSSPQAQPPRPAELSDEEVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLSSSPQAQPPRPAELSDEEVAE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB8 LFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAGHTDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAGHTDR
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB8 SGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKECVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKECVGP
790 800 810 820 830 840
840
pF1KB8 PDPDLEPGETS
:::::::::::
XP_011 PDPDLEPGETS
850
>>XP_016885146 (OMIM: 300408) PREDICTED: GRIP1-associate (775 aa)
initn: 2685 init1: 2685 opt: 2795 Z-score: 1093.4 bits: 213.2 E(85289): 3.7e-54
Smith-Waterman score: 4787; 98.6% identity (98.6% similar) in 775 aa overlap (77-841:1-775)
50 60 70 80 90 100
pF1KB8 YLDKEFSKAQKALSKSKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQ
::::::::::::::::::::::::::::::
XP_016 MLQAKLHSQEEDFRLQNSTLMAEFSKLCSQ
10 20 30
110 120 130 140 150 160
pF1KB8 MEQLEQENQQLKEGAAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEQLEQENQQLKEGAAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFS
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB8 AVSEGQGDPPGGPAPTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQE
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVSEGQGDPPGGLAPTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQE
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB8 ELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELE
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB8 AANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALE
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB8 QIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQ
280 290 300 310 320 330
410 420 430 440 450
pF1KB8 EIGQEKEQLTQELQEARK----------SAEKRKAMLDELAMETLQEKSQHKEELGAVRL
:::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_016 EIGQEKEQLTQELQEARKEVDCHRPGPQSAEKRKAMLDELAMETLQEKSQHKEELGAVRL
340 350 360 370 380 390
460 470 480 490 500 510
pF1KB8 RHEKEVLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHEKEVLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVH
400 410 420 430 440 450
520 530 540 550 560 570
pF1KB8 SMDGAKGWFERRLKEAEESLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMDGAKGWFERRLKEAEESLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQ
460 470 480 490 500 510
580 590 600 610 620 630
pF1KB8 EERDCHLKTISSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EERDCHLKTISSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDIL
520 530 540 550 560 570
640 650 660 670 680 690
pF1KB8 TNSKSRSGLEELVLSEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLSSSPQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNSKSRSGLEELVLSEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLSSSPQAQ
580 590 600 610 620 630
700 710 720 730 740 750
pF1KB8 PPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMD
640 650 660 670 680 690
760 770 780 790 800 810
pF1KB8 SRIDVSVAAGHTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRIDVSVAAGHTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVL
700 710 720 730 740 750
820 830 840
pF1KB8 SQEIVRLSKECVGPPDPDLEPGETS
:::::::::::::::::::::::::
XP_016 SQEIVRLSKECVGPPDPDLEPGETS
760 770
>>XP_011542239 (OMIM: 300408) PREDICTED: GRIP1-associate (775 aa)
initn: 2685 init1: 2685 opt: 2795 Z-score: 1093.4 bits: 213.2 E(85289): 3.7e-54
Smith-Waterman score: 4787; 98.6% identity (98.6% similar) in 775 aa overlap (77-841:1-775)
50 60 70 80 90 100
pF1KB8 YLDKEFSKAQKALSKSKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQ
::::::::::::::::::::::::::::::
XP_011 MLQAKLHSQEEDFRLQNSTLMAEFSKLCSQ
10 20 30
110 120 130 140 150 160
pF1KB8 MEQLEQENQQLKEGAAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEQLEQENQQLKEGAAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFS
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB8 AVSEGQGDPPGGPAPTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQE
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVSEGQGDPPGGLAPTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQE
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB8 ELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELE
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB8 AANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALE
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB8 QIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQ
280 290 300 310 320 330
410 420 430 440 450
pF1KB8 EIGQEKEQLTQELQEARK----------SAEKRKAMLDELAMETLQEKSQHKEELGAVRL
:::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_011 EIGQEKEQLTQELQEARKEVDCHRPGPQSAEKRKAMLDELAMETLQEKSQHKEELGAVRL
340 350 360 370 380 390
460 470 480 490 500 510
pF1KB8 RHEKEVLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHEKEVLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVH
400 410 420 430 440 450
520 530 540 550 560 570
pF1KB8 SMDGAKGWFERRLKEAEESLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMDGAKGWFERRLKEAEESLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQ
460 470 480 490 500 510
580 590 600 610 620 630
pF1KB8 EERDCHLKTISSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EERDCHLKTISSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDIL
520 530 540 550 560 570
640 650 660 670 680 690
pF1KB8 TNSKSRSGLEELVLSEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLSSSPQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNSKSRSGLEELVLSEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLSSSPQAQ
580 590 600 610 620 630
700 710 720 730 740 750
pF1KB8 PPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMD
640 650 660 670 680 690
760 770 780 790 800 810
pF1KB8 SRIDVSVAAGHTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRIDVSVAAGHTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVL
700 710 720 730 740 750
820 830 840
pF1KB8 SQEIVRLSKECVGPPDPDLEPGETS
:::::::::::::::::::::::::
XP_011 SQEIVRLSKECVGPPDPDLEPGETS
760 770
>>XP_011542238 (OMIM: 300408) PREDICTED: GRIP1-associate (825 aa)
initn: 4411 init1: 2623 opt: 2724 Z-score: 1066.0 bits: 208.2 E(85289): 1.2e-52
Smith-Waterman score: 5012; 95.7% identity (95.7% similar) in 851 aa overlap (1-841:1-825)
10 20 30 40 50 60
pF1KB8 MAQALSEEEFQRMQAQLLELRTNNYQLSDELRKNGVELTSLRQKVAYLDKEFSKAQKALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAQALSEEEFQRMQAQLLELRTNNYQLSDELRKNGVELTSLRQKVAYLDKEFSKAQKALS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KSKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQMEQLEQENQQLKEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQMEQLEQENQQLKEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFSAVSEGQGDPPGGPA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_011 AAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFSAVSEGQGDPPGGLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 PTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELEAANQSLAELRDQRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELEAANQSLAELRDQRQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 EQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQ
370 380 390 400 410 420
430 440 450 460 470
pF1KB8 EARK----------SAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVRARYE
:::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARKEVDCHRPGPQSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVRARYE
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB8 RELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFERRLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFERRLK
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB8 EAEESLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTISSLK
::: :::::::::::::::::::::::::::::::
XP_011 EAE--------------------------GKEEELQDVRDQLEQAQEERDCHLKTISSLK
550 560 570
600 610 620 630 640 650
pF1KB8 QEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLEELVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLEELVL
580 590 600 610 620 630
660 670 680 690 700 710
pF1KB8 SEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLSSSPQAQPPRPAELSDEEVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLSSSPQAQPPRPAELSDEEVAE
640 650 660 670 680 690
720 730 740 750 760 770
pF1KB8 LFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAGHTDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAGHTDR
700 710 720 730 740 750
780 790 800 810 820 830
pF1KB8 SGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKECVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKECVGP
760 770 780 790 800 810
840
pF1KB8 PDPDLEPGETS
:::::::::::
XP_011 PDPDLEPGETS
820
841 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:25:12 2016 done: Sat Nov 5 16:25:14 2016
Total Scan time: 16.820 Total Display time: 0.300
Function used was FASTA [36.3.4 Apr, 2011]