Result of FASTA (omim) for
pFN21AB9914
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9914, 533 aa
1>>>pF1KB9914 533 - 533 aa - 533 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2993+/-0.000434; mu= 19.4017+/- 0.027
mean_var=82.2298+/-16.401, 0's: 0 Z-trim(111.3): 210 B-trim: 555 in 1/54
Lambda= 0.141436
statistics sampled from 19596 (19815) to 19596 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.6), E-opt: 0.2 (0.232), width: 16
Scan time: 9.440
The best scores are: opt bits E(85289)
NP_001001567 (OMIM: 602973) high affinity cGMP-spe ( 533) 3589 742.6 6.7e-214
NP_001001570 (OMIM: 602973) high affinity cGMP-spe ( 540) 3355 694.9 1.6e-199
NP_001001571 (OMIM: 602973) high affinity cGMP-spe ( 492) 3279 679.4 7e-195
NP_001001574 (OMIM: 602973) high affinity cGMP-spe ( 507) 3119 646.7 4.8e-185
NP_001001568 (OMIM: 602973) high affinity cGMP-spe ( 466) 3112 645.3 1.2e-184
NP_001302462 (OMIM: 602973) high affinity cGMP-spe ( 485) 3112 645.3 1.3e-184
NP_001001581 (OMIM: 602973) high affinity cGMP-spe ( 526) 3024 627.3 3.4e-179
XP_011527900 (OMIM: 602973) PREDICTED: high affini ( 545) 3024 627.4 3.5e-179
NP_001001582 (OMIM: 602973) high affinity cGMP-spe ( 552) 3024 627.4 3.5e-179
NP_001001583 (OMIM: 602973) high affinity cGMP-spe ( 567) 3024 627.4 3.6e-179
NP_002597 (OMIM: 602973) high affinity cGMP-specif ( 593) 3024 627.4 3.7e-179
NP_001001578 (OMIM: 602973) high affinity cGMP-spe ( 491) 2929 607.9 2.2e-173
NP_001001575 (OMIM: 602973) high affinity cGMP-spe ( 433) 2926 607.3 3.1e-173
NP_001001577 (OMIM: 602973) high affinity cGMP-spe ( 459) 2924 606.9 4.2e-173
NP_001001569 (OMIM: 602973) high affinity cGMP-spe ( 465) 2918 605.7 1e-172
NP_001001572 (OMIM: 602973) high affinity cGMP-spe ( 386) 2663 553.6 4e-157
NP_001001579 (OMIM: 602973) high affinity cGMP-spe ( 386) 2663 553.6 4e-157
NP_001001573 (OMIM: 602973) high affinity cGMP-spe ( 386) 2663 553.6 4e-157
NP_001001584 (OMIM: 602973) high affinity cGMP-spe ( 386) 2663 553.6 4e-157
XP_016883855 (OMIM: 602973) PREDICTED: high affini ( 386) 2663 553.6 4e-157
NP_001001585 (OMIM: 602973) high affinity cGMP-spe ( 386) 2663 553.6 4e-157
NP_001001580 (OMIM: 602973) high affinity cGMP-spe ( 376) 2598 540.3 3.9e-153
NP_001001576 (OMIM: 602973) high affinity cGMP-spe ( 376) 2598 540.3 3.9e-153
XP_011527902 (OMIM: 602973) PREDICTED: high affini ( 502) 2087 436.1 1.2e-121
XP_016883856 (OMIM: 602973) PREDICTED: high affini ( 328) 807 174.8 3.6e-43
XP_005259990 (OMIM: 600126) PREDICTED: cAMP-specif ( 582) 606 134.0 1.2e-30
NP_001284371 (OMIM: 600127) cAMP-specific 3',5'-cy ( 503) 605 133.7 1.3e-30
XP_005270981 (OMIM: 600127) PREDICTED: cAMP-specif ( 517) 605 133.7 1.3e-30
XP_005270982 (OMIM: 600127) PREDICTED: cAMP-specif ( 517) 605 133.7 1.3e-30
XP_016856935 (OMIM: 600127) PREDICTED: cAMP-specif ( 530) 605 133.8 1.3e-30
XP_011539868 (OMIM: 600127) PREDICTED: cAMP-specif ( 530) 605 133.8 1.3e-30
XP_006710743 (OMIM: 600127) PREDICTED: cAMP-specif ( 531) 605 133.8 1.3e-30
NP_006193 (OMIM: 600126) cAMP-specific 3',5'-cycli ( 647) 606 134.0 1.3e-30
NP_001032416 (OMIM: 600127) cAMP-specific 3',5'-cy ( 564) 605 133.8 1.4e-30
XP_016856934 (OMIM: 600127) PREDICTED: cAMP-specif ( 597) 605 133.8 1.4e-30
NP_001284369 (OMIM: 600127) cAMP-specific 3',5'-cy ( 644) 605 133.8 1.5e-30
NP_001284370 (OMIM: 600127) cAMP-specific 3',5'-cy ( 661) 605 133.8 1.5e-30
NP_001104779 (OMIM: 600126) cAMP-specific 3',5'-cy ( 825) 606 134.1 1.6e-30
NP_001104778 (OMIM: 600126) cAMP-specific 3',5'-cy ( 860) 606 134.1 1.6e-30
NP_001230050 (OMIM: 600126) cAMP-specific 3',5'-cy ( 864) 606 134.1 1.6e-30
XP_011526356 (OMIM: 600126) PREDICTED: cAMP-specif ( 864) 606 134.1 1.6e-30
NP_001032417 (OMIM: 600127) cAMP-specific 3',5'-cy ( 721) 605 133.9 1.7e-30
XP_016882354 (OMIM: 600126) PREDICTED: cAMP-specif ( 885) 606 134.1 1.7e-30
NP_001104777 (OMIM: 600126) cAMP-specific 3',5'-cy ( 886) 606 134.1 1.7e-30
NP_002591 (OMIM: 600127) cAMP-specific 3',5'-cycli ( 736) 605 133.9 1.7e-30
NP_001032418 (OMIM: 600127) cAMP-specific 3',5'-cy ( 736) 605 133.9 1.7e-30
NP_001184150 (OMIM: 600129,606799,614613) cAMP-spe ( 507) 593 131.3 6.9e-30
NP_001184152 (OMIM: 600129,606799,614613) cAMP-spe ( 518) 593 131.3 7e-30
XP_016865060 (OMIM: 600129,606799,614613) PREDICTE ( 553) 593 131.3 7.4e-30
XP_016865059 (OMIM: 600129,606799,614613) PREDICTE ( 553) 593 131.3 7.4e-30
>>NP_001001567 (OMIM: 602973) high affinity cGMP-specifi (533 aa)
initn: 3589 init1: 3589 opt: 3589 Z-score: 3961.1 bits: 742.6 E(85289): 6.7e-214
Smith-Waterman score: 3589; 100.0% identity (100.0% similar) in 533 aa overlap (1-533:1-533)
10 20 30 40 50 60
pF1KB9 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 VSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
430 440 450 460 470 480
490 500 510 520 530
pF1KB9 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
490 500 510 520 530
>>NP_001001570 (OMIM: 602973) high affinity cGMP-specifi (540 aa)
initn: 3381 init1: 2918 opt: 3355 Z-score: 3703.0 bits: 694.9 E(85289): 1.6e-199
Smith-Waterman score: 3355; 93.5% identity (96.3% similar) in 541 aa overlap (1-533:1-540)
10 20 30 40 50 60
pF1KB9 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
10 20 30 40 50 60
70 80 90 100 110
pF1KB9 VSIDPTMPANSERTPYKVRPVAIKQL---SEREELI---QSVLAQV-AEQFS-RAFKINE
:::::::::::::. . .....: .: .:: ... ..: . :::::::
NP_001 VSIDPTMPANSERNEL-ILYTSLRNLLFLPSKESWASHQHSVQSETCGHQATLRAFKINE
70 80 90 100 110
120 130 140 150 160 170
pF1KB9 LKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 KLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 VTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICH
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 DLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQI
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB9 RQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEV
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB9 AEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLF
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB9 PMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDC
480 490 500 510 520 530
pF1KB9 A
:
NP_001 A
540
>>NP_001001571 (OMIM: 602973) high affinity cGMP-specifi (492 aa)
initn: 3279 init1: 3279 opt: 3279 Z-score: 3619.7 bits: 679.4 E(85289): 7e-195
Smith-Waterman score: 3279; 100.0% identity (100.0% similar) in 487 aa overlap (47-533:6-492)
20 30 40 50 60 70
pF1KB9 IDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPY
::::::::::::::::::::::::::::::
NP_001 MDAFRRNTTISLLTTDDAMVSIDPTMPANSERTPY
10 20 30
80 90 100 110 120 130
pF1KB9 KVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVV
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB9 EIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEAL
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB9 RKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRH
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB9 CFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYN
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB9 DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFK
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB9 EKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGL
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB9 PVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRI
400 410 420 430 440 450
500 510 520 530
pF1KB9 DDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
:::::::::::::::::::::::::::::::::::::
NP_001 DDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
460 470 480 490
>>NP_001001574 (OMIM: 602973) high affinity cGMP-specifi (507 aa)
initn: 3119 init1: 3119 opt: 3119 Z-score: 3443.1 bits: 646.7 E(85289): 4.8e-185
Smith-Waterman score: 3367; 95.1% identity (95.1% similar) in 533 aa overlap (1-533:1-507)
10 20 30 40 50 60
pF1KB9 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPR-------------
10 20 30 40
70 80 90 100 110 120
pF1KB9 VSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -------------TPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH
50 60 70 80 90
130 140 150 160 170 180
pF1KB9 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB9 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB9 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB9 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB9 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB9 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
400 410 420 430 440 450
490 500 510 520 530
pF1KB9 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
460 470 480 490 500
>>NP_001001568 (OMIM: 602973) high affinity cGMP-specifi (466 aa)
initn: 3112 init1: 3112 opt: 3112 Z-score: 3435.9 bits: 645.3 E(85289): 1.2e-184
Smith-Waterman score: 3112; 100.0% identity (100.0% similar) in 460 aa overlap (74-533:7-466)
50 60 70 80 90 100
pF1KB9 GLPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQ
::::::::::::::::::::::::::::::
NP_001 MDAFRSTPYKVRPVAIKQLSEREELIQSVLAQVAEQ
10 20 30
110 120 130 140 150 160
pF1KB9 FSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPC
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB9 KYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLG
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB9 LVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDIL
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB9 ILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSN
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB9 IPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDI
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB9 SNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIP
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB9 MFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSR
400 410 420 430 440 450
530
pF1KB9 DVKNSEGDCA
::::::::::
NP_001 DVKNSEGDCA
460
>>NP_001302462 (OMIM: 602973) high affinity cGMP-specifi (485 aa)
initn: 3112 init1: 3112 opt: 3112 Z-score: 3435.7 bits: 645.3 E(85289): 1.3e-184
Smith-Waterman score: 3112; 100.0% identity (100.0% similar) in 460 aa overlap (74-533:26-485)
50 60 70 80 90 100
pF1KB9 GLPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQ
::::::::::::::::::::::::::::::
NP_001 MSSFSIHHSVTCCFYLVRSHGRPTSTPYKVRPVAIKQLSEREELIQSVLAQVAEQ
10 20 30 40 50
110 120 130 140 150 160
pF1KB9 FSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPC
60 70 80 90 100 110
170 180 190 200 210 220
pF1KB9 KYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLG
120 130 140 150 160 170
230 240 250 260 270 280
pF1KB9 LVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDIL
180 190 200 210 220 230
290 300 310 320 330 340
pF1KB9 ILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSN
240 250 260 270 280 290
350 360 370 380 390 400
pF1KB9 IPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDI
300 310 320 330 340 350
410 420 430 440 450 460
pF1KB9 SNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIP
360 370 380 390 400 410
470 480 490 500 510 520
pF1KB9 MFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSR
420 430 440 450 460 470
530
pF1KB9 DVKNSEGDCA
::::::::::
NP_001 DVKNSEGDCA
480
>>NP_001001581 (OMIM: 602973) high affinity cGMP-specifi (526 aa)
initn: 3098 init1: 3023 opt: 3024 Z-score: 3338.2 bits: 627.3 E(85289): 3.4e-179
Smith-Waterman score: 3024; 94.3% identity (96.0% similar) in 477 aa overlap (57-533:57-526)
30 40 50 60 70 80
pF1KB9 SKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQL
....: : : . . .. :
NP_001 RTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIPP------
30 40 50 60 70 80
90 100 110 120 130 140
pF1KB9 SEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK
90 100 110 120 130
150 160 170 180 190 200
pF1KB9 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW
140 150 160 170 180 190
210 220 230 240 250 260
pF1KB9 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS
200 210 220 230 240 250
270 280 290 300 310 320
pF1KB9 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC
260 270 280 290 300 310
330 340 350 360 370 380
pF1KB9 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN
320 330 340 350 360 370
390 400 410 420 430 440
pF1KB9 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK
380 390 400 410 420 430
450 460 470 480 490 500
pF1KB9 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
440 450 460 470 480 490
510 520 530
pF1KB9 TDSLTSGATEKSRERSRDVKNSEGDCA
:::::::::::::::::::::::::::
NP_001 TDSLTSGATEKSRERSRDVKNSEGDCA
500 510 520
>>XP_011527900 (OMIM: 602973) PREDICTED: high affinity c (545 aa)
initn: 3098 init1: 3023 opt: 3024 Z-score: 3337.9 bits: 627.4 E(85289): 3.5e-179
Smith-Waterman score: 3024; 94.3% identity (96.0% similar) in 477 aa overlap (57-533:76-545)
30 40 50 60 70 80
pF1KB9 SKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQL
....: : : . . .. :
XP_011 RTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIPP------
50 60 70 80 90
90 100 110 120 130 140
pF1KB9 SEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 -EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK
100 110 120 130 140 150
150 160 170 180 190 200
pF1KB9 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW
160 170 180 190 200 210
210 220 230 240 250 260
pF1KB9 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS
220 230 240 250 260 270
270 280 290 300 310 320
pF1KB9 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC
280 290 300 310 320 330
330 340 350 360 370 380
pF1KB9 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN
340 350 360 370 380 390
390 400 410 420 430 440
pF1KB9 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK
400 410 420 430 440 450
450 460 470 480 490 500
pF1KB9 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
460 470 480 490 500 510
510 520 530
pF1KB9 TDSLTSGATEKSRERSRDVKNSEGDCA
:::::::::::::::::::::::::::
XP_011 TDSLTSGATEKSRERSRDVKNSEGDCA
520 530 540
>>NP_001001582 (OMIM: 602973) high affinity cGMP-specifi (552 aa)
initn: 3265 init1: 3023 opt: 3024 Z-score: 3337.9 bits: 627.4 E(85289): 3.5e-179
Smith-Waterman score: 3149; 89.0% identity (89.0% similar) in 547 aa overlap (47-533:6-552)
20 30 40 50 60 70
pF1KB9 IDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPY
::::::::::::::::::::::::::::::
NP_001 MDAFRRNTTISLLTTDDAMVSIDPTMPANSERTPY
10 20 30
80
pF1KB9 KVRPVAIKQLS-------------------------------------------------
:::::::::::
NP_001 KVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQ
40 50 60 70 80 90
90 100 110 120 130
pF1KB9 -----------EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVV
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVV
100 110 120 130 140 150
140 150 160 170 180 190
pF1KB9 EIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEAL
160 170 180 190 200 210
200 210 220 230 240 250
pF1KB9 RKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRH
220 230 240 250 260 270
260 270 280 290 300 310
pF1KB9 CFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYN
280 290 300 310 320 330
320 330 340 350 360 370
pF1KB9 DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFK
340 350 360 370 380 390
380 390 400 410 420 430
pF1KB9 EKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGL
400 410 420 430 440 450
440 450 460 470 480 490
pF1KB9 PVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRI
460 470 480 490 500 510
500 510 520 530
pF1KB9 DDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
:::::::::::::::::::::::::::::::::::::
NP_001 DDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
520 530 540 550
>>NP_001001583 (OMIM: 602973) high affinity cGMP-specifi (567 aa)
initn: 3326 init1: 3023 opt: 3024 Z-score: 3337.7 bits: 627.4 E(85289): 3.6e-179
Smith-Waterman score: 3249; 88.3% identity (90.6% similar) in 565 aa overlap (3-533:3-567)
10 20 30 40 50
pF1KB9 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRN------TTISLL
:::::::::::::::::::::::::::::::::::::::::::::. ..:. :
NP_001 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRTPYKVRPVAIKQL
10 20 30 40 50 60
60 70 80
pF1KB9 TT-------------------DDAMVSID-PTMPANSERTPYKVRPVAIKQL--------
.. : .:... : . : . :: .
NP_001 SAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIP
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB9 SEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB9 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB9 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB9 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB9 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN
370 380 390 400 410 420
390 400 410 420 430 440
pF1KB9 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK
430 440 450 460 470 480
450 460 470 480 490 500
pF1KB9 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
490 500 510 520 530 540
510 520 530
pF1KB9 TDSLTSGATEKSRERSRDVKNSEGDCA
:::::::::::::::::::::::::::
NP_001 TDSLTSGATEKSRERSRDVKNSEGDCA
550 560
533 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 14:49:29 2016 done: Sat Nov 5 14:49:30 2016
Total Scan time: 9.440 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]