Result of FASTA (ccds) for
pFN21AB9914
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9914, 533 aa
1>>>pF1KB9914 533 - 533 aa - 533 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8647+/-0.0011; mu= 15.8990+/- 0.066
mean_var=81.6460+/-15.953, 0's: 0 Z-trim(104.1): 73 B-trim: 40 in 1/49
Lambda= 0.141941
statistics sampled from 7676 (7751) to 7676 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.609), E-opt: 0.2 (0.238), width: 16
Scan time: 2.730
The best scores are: opt bits E(32554)
CCDS33568.1 PDE9A gene_id:5152|Hs108|chr21 ( 533) 3589 745.2 4.4e-215
CCDS33567.1 PDE9A gene_id:5152|Hs108|chr21 ( 540) 3355 697.3 1.2e-200
CCDS42943.1 PDE9A gene_id:5152|Hs108|chr21 ( 492) 3279 681.7 5.4e-196
CCDS42941.1 PDE9A gene_id:5152|Hs108|chr21 ( 507) 3119 648.9 4e-186
CCDS42946.1 PDE9A gene_id:5152|Hs108|chr21 ( 466) 3112 647.5 1e-185
CCDS42945.1 PDE9A gene_id:5152|Hs108|chr21 ( 526) 3024 629.5 3e-180
CCDS42942.1 PDE9A gene_id:5152|Hs108|chr21 ( 552) 3024 629.5 3.1e-180
CCDS33569.1 PDE9A gene_id:5152|Hs108|chr21 ( 567) 3024 629.5 3.2e-180
CCDS13690.1 PDE9A gene_id:5152|Hs108|chr21 ( 593) 3024 629.5 3.3e-180
CCDS33570.1 PDE9A gene_id:5152|Hs108|chr21 ( 491) 2929 610.0 2e-174
CCDS42947.1 PDE9A gene_id:5152|Hs108|chr21 ( 433) 2926 609.4 2.8e-174
CCDS42944.1 PDE9A gene_id:5152|Hs108|chr21 ( 459) 2924 609.0 3.9e-174
CCDS33571.1 PDE9A gene_id:5152|Hs108|chr21 ( 465) 2918 607.7 9.2e-174
CCDS72802.1 PDE4B gene_id:5142|Hs108|chr1 ( 503) 605 134.1 3.7e-31
CCDS12238.1 PDE4A gene_id:5141|Hs108|chr19 ( 647) 606 134.4 4e-31
CCDS30743.1 PDE4B gene_id:5142|Hs108|chr1 ( 564) 605 134.1 4.1e-31
CCDS45963.1 PDE4A gene_id:5141|Hs108|chr19 ( 825) 606 134.4 4.9e-31
CCDS30742.1 PDE4B gene_id:5142|Hs108|chr1 ( 721) 605 134.2 5e-31
CCDS45962.1 PDE4A gene_id:5141|Hs108|chr19 ( 860) 606 134.4 5.1e-31
CCDS58649.1 PDE4A gene_id:5141|Hs108|chr19 ( 864) 606 134.4 5.1e-31
CCDS632.1 PDE4B gene_id:5142|Hs108|chr1 ( 736) 605 134.2 5.1e-31
CCDS45961.1 PDE4A gene_id:5141|Hs108|chr19 ( 886) 606 134.4 5.2e-31
CCDS56370.1 PDE4D gene_id:5144|Hs108|chr5 ( 507) 593 131.6 2.1e-30
CCDS56369.1 PDE4D gene_id:5144|Hs108|chr5 ( 518) 593 131.6 2.1e-30
CCDS54858.1 PDE4D gene_id:5144|Hs108|chr5 ( 673) 593 131.7 2.6e-30
CCDS56371.1 PDE4D gene_id:5144|Hs108|chr5 ( 679) 593 131.7 2.6e-30
CCDS56372.1 PDE4D gene_id:5144|Hs108|chr5 ( 687) 593 131.7 2.7e-30
CCDS56373.1 PDE4D gene_id:5144|Hs108|chr5 ( 745) 593 131.7 2.8e-30
CCDS54859.1 PDE4D gene_id:5144|Hs108|chr5 ( 748) 593 131.7 2.9e-30
CCDS47213.1 PDE4D gene_id:5144|Hs108|chr5 ( 809) 593 131.8 3.1e-30
CCDS46016.1 PDE4C gene_id:5143|Hs108|chr19 ( 606) 571 127.2 5.4e-29
CCDS42523.1 PDE4C gene_id:5143|Hs108|chr19 ( 680) 571 127.2 6e-29
CCDS12373.1 PDE4C gene_id:5143|Hs108|chr19 ( 712) 571 127.2 6.2e-29
CCDS34901.1 PDE7A gene_id:5150|Hs108|chr8 ( 456) 544 121.6 2e-27
CCDS56538.1 PDE7A gene_id:5150|Hs108|chr8 ( 482) 544 121.6 2.1e-27
CCDS42786.1 PDE11A gene_id:50940|Hs108|chr2 ( 489) 534 119.6 8.7e-27
CCDS46459.1 PDE11A gene_id:50940|Hs108|chr2 ( 575) 534 119.6 1e-26
CCDS42785.1 PDE11A gene_id:50940|Hs108|chr2 ( 683) 534 119.6 1.1e-26
CCDS33334.1 PDE11A gene_id:50940|Hs108|chr2 ( 933) 534 119.7 1.5e-26
CCDS73345.1 PDE2A gene_id:5138|Hs108|chr11 ( 920) 526 118.1 4.6e-26
CCDS53678.1 PDE2A gene_id:5138|Hs108|chr11 ( 932) 526 118.1 4.6e-26
CCDS44670.1 PDE2A gene_id:5138|Hs108|chr11 ( 934) 526 118.1 4.6e-26
CCDS8216.1 PDE2A gene_id:5138|Hs108|chr11 ( 941) 526 118.1 4.7e-26
CCDS5175.1 PDE7B gene_id:27115|Hs108|chr6 ( 450) 519 116.5 6.8e-26
CCDS74612.1 PDE1A gene_id:5136|Hs108|chr2 ( 501) 504 113.4 6.3e-25
CCDS58741.1 PDE1A gene_id:5136|Hs108|chr2 ( 519) 504 113.4 6.5e-25
CCDS33344.1 PDE1A gene_id:5136|Hs108|chr2 ( 535) 504 113.4 6.6e-25
CCDS2285.1 PDE1A gene_id:5136|Hs108|chr2 ( 545) 504 113.4 6.7e-25
CCDS73477.1 PDE1B gene_id:5153|Hs108|chr12 ( 495) 503 113.2 7.2e-25
CCDS53800.1 PDE1B gene_id:5153|Hs108|chr12 ( 516) 503 113.2 7.4e-25
>>CCDS33568.1 PDE9A gene_id:5152|Hs108|chr21 (533 aa)
initn: 3589 init1: 3589 opt: 3589 Z-score: 3974.8 bits: 745.2 E(32554): 4.4e-215
Smith-Waterman score: 3589; 100.0% identity (100.0% similar) in 533 aa overlap (1-533:1-533)
10 20 30 40 50 60
pF1KB9 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 VSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 VSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
430 440 450 460 470 480
490 500 510 520 530
pF1KB9 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
490 500 510 520 530
>>CCDS33567.1 PDE9A gene_id:5152|Hs108|chr21 (540 aa)
initn: 3381 init1: 2918 opt: 3355 Z-score: 3715.8 bits: 697.3 E(32554): 1.2e-200
Smith-Waterman score: 3355; 93.5% identity (96.3% similar) in 541 aa overlap (1-533:1-540)
10 20 30 40 50 60
pF1KB9 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
10 20 30 40 50 60
70 80 90 100 110
pF1KB9 VSIDPTMPANSERTPYKVRPVAIKQL---SEREELI---QSVLAQV-AEQFS-RAFKINE
:::::::::::::. . .....: .: .:: ... ..: . :::::::
CCDS33 VSIDPTMPANSERNEL-ILYTSLRNLLFLPSKESWASHQHSVQSETCGHQATLRAFKINE
70 80 90 100 110
120 130 140 150 160 170
pF1KB9 LKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 KLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 KLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 VTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 VTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICH
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 DLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 DLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQI
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB9 RQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 RQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEV
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB9 AEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 AEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLF
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB9 PMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 PMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDC
480 490 500 510 520 530
pF1KB9 A
:
CCDS33 A
540
>>CCDS42943.1 PDE9A gene_id:5152|Hs108|chr21 (492 aa)
initn: 3279 init1: 3279 opt: 3279 Z-score: 3632.3 bits: 681.7 E(32554): 5.4e-196
Smith-Waterman score: 3279; 100.0% identity (100.0% similar) in 487 aa overlap (47-533:6-492)
20 30 40 50 60 70
pF1KB9 IDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPY
::::::::::::::::::::::::::::::
CCDS42 MDAFRRNTTISLLTTDDAMVSIDPTMPANSERTPY
10 20 30
80 90 100 110 120 130
pF1KB9 KVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 KVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVV
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB9 EIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 EIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEAL
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB9 RKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 RKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRH
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB9 CFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 CFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYN
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB9 DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFK
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB9 EKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 EKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGL
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB9 PVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRI
400 410 420 430 440 450
500 510 520 530
pF1KB9 DDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
:::::::::::::::::::::::::::::::::::::
CCDS42 DDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
460 470 480 490
>>CCDS42941.1 PDE9A gene_id:5152|Hs108|chr21 (507 aa)
initn: 3119 init1: 3119 opt: 3119 Z-score: 3455.0 bits: 648.9 E(32554): 4e-186
Smith-Waterman score: 3367; 95.1% identity (95.1% similar) in 533 aa overlap (1-533:1-507)
10 20 30 40 50 60
pF1KB9 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
:::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPR-------------
10 20 30 40
70 80 90 100 110 120
pF1KB9 VSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH
:::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 -------------TPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH
50 60 70 80 90
130 140 150 160 170 180
pF1KB9 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB9 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB9 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB9 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB9 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB9 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
400 410 420 430 440 450
490 500 510 520 530
pF1KB9 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
460 470 480 490 500
>>CCDS42946.1 PDE9A gene_id:5152|Hs108|chr21 (466 aa)
initn: 3112 init1: 3112 opt: 3112 Z-score: 3447.8 bits: 647.5 E(32554): 1e-185
Smith-Waterman score: 3112; 100.0% identity (100.0% similar) in 460 aa overlap (74-533:7-466)
50 60 70 80 90 100
pF1KB9 GLPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQ
::::::::::::::::::::::::::::::
CCDS42 MDAFRSTPYKVRPVAIKQLSEREELIQSVLAQVAEQ
10 20 30
110 120 130 140 150 160
pF1KB9 FSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 FSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPC
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB9 KYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 KYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLG
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB9 LVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDIL
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB9 ILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 ILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSN
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB9 IPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 IPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDI
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB9 SNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 SNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIP
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB9 MFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSR
400 410 420 430 440 450
530
pF1KB9 DVKNSEGDCA
::::::::::
CCDS42 DVKNSEGDCA
460
>>CCDS42945.1 PDE9A gene_id:5152|Hs108|chr21 (526 aa)
initn: 3098 init1: 3023 opt: 3024 Z-score: 3349.6 bits: 629.5 E(32554): 3e-180
Smith-Waterman score: 3024; 94.3% identity (96.0% similar) in 477 aa overlap (57-533:57-526)
30 40 50 60 70 80
pF1KB9 SKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQL
....: : : . . .. :
CCDS42 RTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIPP------
30 40 50 60 70 80
90 100 110 120 130 140
pF1KB9 SEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 -EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK
90 100 110 120 130
150 160 170 180 190 200
pF1KB9 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW
140 150 160 170 180 190
210 220 230 240 250 260
pF1KB9 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS
200 210 220 230 240 250
270 280 290 300 310 320
pF1KB9 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC
260 270 280 290 300 310
330 340 350 360 370 380
pF1KB9 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN
320 330 340 350 360 370
390 400 410 420 430 440
pF1KB9 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK
380 390 400 410 420 430
450 460 470 480 490 500
pF1KB9 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
440 450 460 470 480 490
510 520 530
pF1KB9 TDSLTSGATEKSRERSRDVKNSEGDCA
:::::::::::::::::::::::::::
CCDS42 TDSLTSGATEKSRERSRDVKNSEGDCA
500 510 520
>>CCDS42942.1 PDE9A gene_id:5152|Hs108|chr21 (552 aa)
initn: 3265 init1: 3023 opt: 3024 Z-score: 3349.3 bits: 629.5 E(32554): 3.1e-180
Smith-Waterman score: 3149; 89.0% identity (89.0% similar) in 547 aa overlap (47-533:6-552)
20 30 40 50 60 70
pF1KB9 IDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPY
::::::::::::::::::::::::::::::
CCDS42 MDAFRRNTTISLLTTDDAMVSIDPTMPANSERTPY
10 20 30
80
pF1KB9 KVRPVAIKQLS-------------------------------------------------
:::::::::::
CCDS42 KVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQ
40 50 60 70 80 90
90 100 110 120 130
pF1KB9 -----------EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVV
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 GCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVV
100 110 120 130 140 150
140 150 160 170 180 190
pF1KB9 EIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 EIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEAL
160 170 180 190 200 210
200 210 220 230 240 250
pF1KB9 RKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 RKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRH
220 230 240 250 260 270
260 270 280 290 300 310
pF1KB9 CFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 CFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYN
280 290 300 310 320 330
320 330 340 350 360 370
pF1KB9 DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFK
340 350 360 370 380 390
380 390 400 410 420 430
pF1KB9 EKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 EKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGL
400 410 420 430 440 450
440 450 460 470 480 490
pF1KB9 PVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRI
460 470 480 490 500 510
500 510 520 530
pF1KB9 DDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
:::::::::::::::::::::::::::::::::::::
CCDS42 DDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
520 530 540 550
>>CCDS33569.1 PDE9A gene_id:5152|Hs108|chr21 (567 aa)
initn: 3326 init1: 3023 opt: 3024 Z-score: 3349.1 bits: 629.5 E(32554): 3.2e-180
Smith-Waterman score: 3249; 88.3% identity (90.6% similar) in 565 aa overlap (3-533:3-567)
10 20 30 40 50
pF1KB9 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRN------TTISLL
:::::::::::::::::::::::::::::::::::::::::::::. ..:. :
CCDS33 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRTPYKVRPVAIKQL
10 20 30 40 50 60
60 70 80
pF1KB9 TT-------------------DDAMVSID-PTMPANSERTPYKVRPVAIKQL--------
.. : .:... : . : . :: .
CCDS33 SAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIP
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB9 SEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 PEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB9 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB9 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB9 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB9 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN
370 380 390 400 410 420
390 400 410 420 430 440
pF1KB9 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK
430 440 450 460 470 480
450 460 470 480 490 500
pF1KB9 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
490 500 510 520 530 540
510 520 530
pF1KB9 TDSLTSGATEKSRERSRDVKNSEGDCA
:::::::::::::::::::::::::::
CCDS33 TDSLTSGATEKSRERSRDVKNSEGDCA
550 560
>>CCDS13690.1 PDE9A gene_id:5152|Hs108|chr21 (593 aa)
initn: 3575 init1: 3023 opt: 3024 Z-score: 3348.8 bits: 629.5 E(32554): 3.3e-180
Smith-Waterman score: 3279; 89.4% identity (89.4% similar) in 565 aa overlap (29-533:29-593)
10 20 30 40 50 60
pF1KB9 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
::::::::::::::::::::::::::::::::
CCDS13 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
10 20 30 40 50 60
70 80
pF1KB9 VSIDPTMPANSERTPYKVRPVAIKQLS---------------------------------
:::::::::::::::::::::::::::
CCDS13 VSIDPTMPANSERTPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRRE
70 80 90 100 110 120
90 100 110 120
pF1KB9 ---------------------------EREELIQSVLAQVAEQFSRAFKINELKAEVANH
:::::::::::::::::::::::::::::::::
CCDS13 GAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANH
130 140 150 160 170 180
130 140 150 160 170 180
pF1KB9 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
190 200 210 220 230 240
190 200 210 220 230 240
pF1KB9 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
250 260 270 280 290 300
250 260 270 280 290 300
pF1KB9 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB9 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
370 380 390 400 410 420
370 380 390 400 410 420
pF1KB9 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
430 440 450 460 470 480
430 440 450 460 470 480
pF1KB9 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
490 500 510 520 530 540
490 500 510 520 530
pF1KB9 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
550 560 570 580 590
>>CCDS33570.1 PDE9A gene_id:5152|Hs108|chr21 (491 aa)
initn: 3055 init1: 2918 opt: 2929 Z-score: 3244.9 bits: 610.0 E(32554): 2e-174
Smith-Waterman score: 2986; 86.3% identity (88.4% similar) in 534 aa overlap (1-533:1-491)
10 20 30 40 50 60
pF1KB9 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
::::::::::::::::::::::: :
CCDS33 MGSGSSSYRPKAIYLDIDGRIQK--------EHD--------------------------
10 20
70 80 90 100 110
pF1KB9 VSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFS-RAFKINELKAEVAN
.::. .: :: ... : . .:: ..: . ::::::::::::::
CCDS33 -----HLPADHRRRHGLHRPHHAREF--RTHSVQS--ETCGHQATLRAFKINELKAEVAN
30 40 50 60 70
120 130 140 150 160 170
pF1KB9 HLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 HLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRD
80 90 100 110 120 130
180 190 200 210 220 230
pF1KB9 VPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 VPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWL
140 150 160 170 180 190
240 250 260 270 280 290
pF1KB9 FCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 FCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGY
200 210 220 230 240 250
300 310 320 330 340 350
pF1KB9 NNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 NNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITL
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB9 ILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 ILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDC
320 330 340 350 360 370
420 430 440 450 460 470
pF1KB9 LLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIM
380 390 400 410 420 430
480 490 500 510 520 530
pF1KB9 LQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
440 450 460 470 480 490
533 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 14:49:28 2016 done: Sat Nov 5 14:49:29 2016
Total Scan time: 2.730 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]