Result of FASTA (omim) for
pFN21AB6720
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6720, 134 aa
1>>>pF1KB6720 134 - 134 aa - 134 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8877+/-0.000358; mu= 12.9166+/- 0.022
mean_var=53.7980+/-10.861, 0's: 0 Z-trim(112.6): 39 B-trim: 0 in 0/49
Lambda= 0.174860
statistics sampled from 21600 (21639) to 21600 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.254), width: 16
Scan time: 4.100
The best scores are: opt bits E(85289)
NP_004155 (OMIM: 180280) retinol-binding protein 2 ( 134) 911 237.5 5e-63
NP_443192 (OMIM: 608604) retinoid-binding protein ( 134) 556 147.9 4.6e-36
NP_002890 (OMIM: 180260) retinol-binding protein 1 ( 197) 495 132.6 2.7e-31
NP_113679 (OMIM: 611866) retinol-binding protein 5 ( 135) 460 123.7 9e-29
XP_016875491 (OMIM: 611866) PREDICTED: retinol-bin ( 126) 417 112.8 1.6e-25
NP_001316383 (OMIM: 611866) retinol-binding protei ( 86) 354 96.9 6.9e-21
NP_004093 (OMIM: 134651) fatty acid-binding protei ( 133) 330 90.9 6.6e-19
NP_001437 (OMIM: 602965) fatty acid-binding protei ( 132) 301 83.6 1e-16
NP_001433 (OMIM: 600434) fatty acid-binding protei ( 132) 295 82.1 3e-16
XP_011539309 (OMIM: 134651) PREDICTED: fatty acid- ( 126) 291 81.0 5.8e-16
XP_016855832 (OMIM: 180231) PREDICTED: cellular re ( 138) 286 79.8 1.5e-15
NP_001869 (OMIM: 180231) cellular retinoic acid-bi ( 138) 286 79.8 1.5e-15
NP_001186652 (OMIM: 180231) cellular retinoic acid ( 138) 286 79.8 1.5e-15
NP_004369 (OMIM: 180230) cellular retinoic acid-bi ( 137) 282 78.8 3e-15
NP_001305968 (OMIM: 602965) fatty acid-binding pro ( 166) 272 76.3 2e-14
NP_002668 (OMIM: 170715) myelin P2 protein [Homo s ( 132) 268 75.3 3.4e-14
NP_001124464 (OMIM: 180260) retinol-binding protei ( 157) 262 73.8 1.1e-13
NP_001124465 (OMIM: 180260) retinol-binding protei ( 153) 259 73.0 1.8e-13
NP_001307925 (OMIM: 134651) fatty acid-binding pro ( 144) 257 72.5 2.5e-13
NP_001305971 (OMIM: 602965) fatty acid-binding pro ( 128) 230 65.7 2.5e-11
NP_001305970 (OMIM: 602965) fatty acid-binding pro ( 97) 218 62.6 1.6e-10
NP_000125 (OMIM: 134640) fatty acid-binding protei ( 132) 190 55.6 2.8e-08
NP_001435 (OMIM: 605168) fatty acid-binding protei ( 135) 184 54.1 8.2e-08
NP_001434 (OMIM: 134650) fatty acid-binding protei ( 127) 154 46.5 1.5e-05
NP_001436 (OMIM: 600422) gastrotropin isoform 2 [H ( 128) 130 40.4 0.00099
NP_001124430 (OMIM: 600422) gastrotropin isoform 1 ( 177) 130 40.5 0.0013
NP_001035532 (OMIM: 600422) gastrotropin isoform 1 ( 177) 130 40.5 0.0013
>>NP_004155 (OMIM: 180280) retinol-binding protein 2 [Ho (134 aa)
initn: 911 init1: 911 opt: 911 Z-score: 1252.5 bits: 237.5 E(85289): 5e-63
Smith-Waterman score: 911; 100.0% identity (100.0% similar) in 134 aa overlap (1-134:1-134)
10 20 30 40 50 60
pF1KB6 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLEL
70 80 90 100 110 120
130
pF1KB6 TCGDQVCRQVFKKK
::::::::::::::
NP_004 TCGDQVCRQVFKKK
130
>>NP_443192 (OMIM: 608604) retinoid-binding protein 7 [H (134 aa)
initn: 558 init1: 545 opt: 556 Z-score: 768.5 bits: 147.9 E(85289): 4.6e-36
Smith-Waterman score: 556; 59.4% identity (80.5% similar) in 133 aa overlap (1-133:1-133)
10 20 30 40 50 60
pF1KB6 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN
: : .::: . :..:::::: :: ::::::::: : :::.:.::.: .:.:..::
NP_443 MPADLSGTWTLLSSDNFEGYMLALGIDFATRKIAKLLKPQKVIEQNGDSFTIHTNSSLRN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLEL
: : : :: :::: ...::::. :.:: :..: :.:.:::::.:::: .:::::::.::.
NP_443 YFVKFKVGEEFDEDNRGLDNRKCKSLVIWDNDRLTCIQKGEKKNRGWTHWIEGDKLHLEM
70 80 90 100 110 120
130
pF1KB6 TCGDQVCRQVFKKK
: :::.:.:..
NP_443 FCEGQVCKQTFQRA
130
>>NP_002890 (OMIM: 180260) retinol-binding protein 1 iso (197 aa)
initn: 464 init1: 464 opt: 495 Z-score: 682.8 bits: 132.6 E(85289): 2.7e-31
Smith-Waterman score: 495; 55.6% identity (72.9% similar) in 133 aa overlap (1-133:63-195)
10 20 30
pF1KB6 MTRDQNGTWEMESNENFEGYMKALDIDFAT
: : .: :.: ::::: :..:::.. :
NP_002 HHPRSTGSRCPGSLQPSRPLVANWLQSLPEMPVDFTGYWKMLVNENFEEYLRALDVNVAL
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB6 RKIAVRLTQTKVIDQDGDNFKTKTTSTFRNYDVDFTVGVEFDEYTKSLDNRHVKALVTWE
:::: : : : ::::.. .: :::::: .:: :: ::.: ..:.:. . :.:.
NP_002 RKIANLLKPDKEIVQDGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMTTVSWD
100 110 120 130 140 150
100 110 120 130
pF1KB6 GDVLVCVQKGEKENRGWKQWIEGDKLYLELTCGDQVCRQVFKKK
:: : ::::::::.::: ::::::.:.::. ::.:::::
NP_002 GDKLQCVQKGEKEGRGWTQWIEGDELHLEMRVEGVVCKQVFKKVQ
160 170 180 190
>>NP_113679 (OMIM: 611866) retinol-binding protein 5 iso (135 aa)
initn: 437 init1: 421 opt: 460 Z-score: 637.6 bits: 123.7 E(85289): 9e-29
Smith-Waterman score: 460; 51.1% identity (80.5% similar) in 133 aa overlap (1-133:1-133)
10 20 30 40 50 60
pF1KB6 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN
: . .: ... :..:.: :..::.:..:.::::. : : :...:... ..: :::::
NP_113 MPPNLTGYYRFVSQKNMEDYLQALNISLAVRKIALLLKPDKEIEHQGNHMTVRTLSTFRN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLEL
: :.: :::::.: .:.:.:. ...:::: . :::::::: ::::..:.::. :::::
NP_113 YTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLEL
70 80 90 100 110 120
130
pF1KB6 TCGDQVCRQVFKKK
: : ::.:::.:
NP_113 TARDAVCEQVFRKVR
130
>>XP_016875491 (OMIM: 611866) PREDICTED: retinol-binding (126 aa)
initn: 433 init1: 417 opt: 417 Z-score: 579.4 bits: 112.8 E(85289): 1.6e-25
Smith-Waterman score: 417; 56.0% identity (81.7% similar) in 109 aa overlap (25-133:16-124)
10 20 30 40 50 60
pF1KB6 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN
::..:.::::. : : :...:... ..: :::::
XP_016 MMNQAQWILKPGTMADISLAVRKIALLLKPDKEIEHQGNHMTVRTLSTFRN
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLEL
: :.: :::::.: .:.:.:. ...:::: . :::::::: ::::..:.::. :::::
XP_016 YTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLEL
60 70 80 90 100 110
130
pF1KB6 TCGDQVCRQVFKKK
: : ::.:::.:
XP_016 TARDAVCEQVFRKVR
120
>>NP_001316383 (OMIM: 611866) retinol-binding protein 5 (86 aa)
initn: 363 init1: 347 opt: 354 Z-score: 496.0 bits: 96.9 E(85289): 6.9e-21
Smith-Waterman score: 354; 61.7% identity (82.7% similar) in 81 aa overlap (53-133:4-84)
30 40 50 60 70 80
pF1KB6 ALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRNYDVDFTVGVEFDEYTKSLDNRH
.: :::::: :.: :::::.: .:.:.:.
NP_001 MTVRTLSTFRNYTVQFDVGVEFEEDLRSVDGRK
10 20 30
90 100 110 120 130
pF1KB6 VKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLELTCGDQVCRQVFKKK
...:::: . :::::::: ::::..:.::. :::::: : ::.:::.:
NP_001 CQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLELTARDAVCEQVFRKVR
40 50 60 70 80
>>NP_004093 (OMIM: 134651) fatty acid-binding protein, h (133 aa)
initn: 306 init1: 229 opt: 330 Z-score: 460.4 bits: 90.9 E(85289): 6.6e-19
Smith-Waterman score: 330; 42.6% identity (71.3% similar) in 129 aa overlap (7-134:7-132)
10 20 30 40 50 60
pF1KB6 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN
:::.. ...::. :::.: . ::::..: : .:...:: . :: :::.:
NP_004 MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKN
10 20 30 40 50 60
70 80 90 100 110
pF1KB6 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGE-KENRGWKQWIEGDKLYLE
...: .:::::: : :.:.::..:: .: :: .:: . .:. .. :.: :: :
NP_004 TEISFKLGVEFDETTA--DDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDG-KLILT
70 80 90 100 110
120 130
pF1KB6 LTCGDQVCRQVFKKK
:: : :: ....:.
NP_004 LTHGTAVCTRTYEKEA
120 130
>>NP_001437 (OMIM: 602965) fatty acid-binding protein, b (132 aa)
initn: 310 init1: 210 opt: 301 Z-score: 420.9 bits: 83.6 E(85289): 1e-16
Smith-Waterman score: 301; 38.1% identity (69.0% similar) in 126 aa overlap (8-133:8-131)
10 20 30 40 50 60
pF1KB6 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN
::.. ...::. ::::: . ::::... : .:.:.::. .: :::.:
NP_001 MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTFKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLEL
...: .: :::: : :.:. :..:. .:: :: .:: . .. .. . :. :. . :
NP_001 TEISFQLGEEFDETTA--DDRNCKSVVSLDGDKLVHIQKWDGKETNFVREIKDGKMVMTL
70 80 90 100 110
130
pF1KB6 TCGDQVCRQVFKKK
: :: : . ..:
NP_001 TFGDVVAVRHYEKA
120 130
>>NP_001433 (OMIM: 600434) fatty acid-binding protein, a (132 aa)
initn: 294 init1: 211 opt: 295 Z-score: 412.7 bits: 82.1 E(85289): 3e-16
Smith-Waterman score: 295; 39.4% identity (66.1% similar) in 127 aa overlap (7-133:7-131)
10 20 30 40 50 60
pF1KB6 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN
:::.. :.:::. ::: . . :::::.: . .:. .:: . :. :::.:
NP_001 MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLEL
...: .: :::: : :.:.::. .: .: ::: ::: . .. :. : ::: .:
NP_001 TEISFILGQEFDEVTA--DDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVEC
70 80 90 100 110
130
pF1KB6 TCGDQVCRQVFKKK
. . .:...
NP_001 VMKGVTSTRVYERA
120 130
>>XP_011539309 (OMIM: 134651) PREDICTED: fatty acid-bind (126 aa)
initn: 281 init1: 229 opt: 291 Z-score: 407.6 bits: 81.0 E(85289): 5.8e-16
Smith-Waterman score: 291; 41.2% identity (71.1% similar) in 114 aa overlap (7-119:7-118)
10 20 30 40 50 60
pF1KB6 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN
:::.. ...::. :::.: . ::::..: : .:...:: . :: :::.:
XP_011 MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKN
10 20 30 40 50 60
70 80 90 100 110
pF1KB6 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGE-KENRGWKQWIEGDKLYLE
...: .:::::: : :.:.::..:: .: :: .:: . .:. .. :.: . .:
XP_011 TEISFKLGVEFDETTA--DDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILME
70 80 90 100 110
120 130
pF1KB6 LTCGDQVCRQVFKKK
XP_011 KLQLRNVK
120
134 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 13:52:35 2016 done: Sat Nov 5 13:52:36 2016
Total Scan time: 4.100 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]