Result of FASTA (omim) for
pFN21AB6212
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6212, 698 aa
1>>>pF1KB6212 698 - 698 aa - 698 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.2032+/-0.000395; mu= 6.3964+/- 0.025
mean_var=166.8911+/-35.330, 0's: 0 Z-trim(117.0): 56 B-trim: 191 in 1/55
Lambda= 0.099279
statistics sampled from 28640 (28696) to 28640 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.336), width: 16
Scan time: 9.510
The best scores are: opt bits E(85289)
NP_602309 (OMIM: 142765) DNA-binding protein RFX2 ( 698) 4661 680.3 6.8e-195
XP_016882597 (OMIM: 142765) PREDICTED: DNA-binding ( 653) 4369 638.4 2.5e-182
XP_011526473 (OMIM: 142765) PREDICTED: DNA-binding ( 723) 3540 519.7 1.5e-146
NP_000626 (OMIM: 142765) DNA-binding protein RFX2 ( 723) 3540 519.7 1.5e-146
XP_016882596 (OMIM: 142765) PREDICTED: DNA-binding ( 678) 3528 518.0 4.7e-146
XP_011526474 (OMIM: 142765) PREDICTED: DNA-binding ( 687) 3279 482.3 2.6e-135
XP_016870490 (OMIM: 601337) PREDICTED: transcripti ( 724) 2891 426.8 1.5e-118
XP_011516302 (OMIM: 601337) PREDICTED: transcripti ( 745) 2820 416.6 1.7e-115
NP_001269045 (OMIM: 601337) transcription factor R ( 749) 2555 378.7 4.6e-104
NP_602304 (OMIM: 601337) transcription factor RFX3 ( 749) 2555 378.7 4.6e-104
XP_011516300 (OMIM: 601337) PREDICTED: transcripti ( 770) 2484 368.5 5.4e-101
XP_006716907 (OMIM: 601337) PREDICTED: transcripti ( 770) 2484 368.5 5.4e-101
XP_011516301 (OMIM: 601337) PREDICTED: transcripti ( 770) 2484 368.5 5.4e-101
XP_006716908 (OMIM: 601337) PREDICTED: transcripti ( 770) 2484 368.5 5.4e-101
XP_016870489 (OMIM: 601337) PREDICTED: transcripti ( 770) 2484 368.5 5.4e-101
XP_006716906 (OMIM: 601337) PREDICTED: transcripti ( 770) 2484 368.5 5.4e-101
XP_006716903 (OMIM: 601337) PREDICTED: transcripti ( 780) 2484 368.5 5.5e-101
NP_002910 (OMIM: 601337) transcription factor RFX3 ( 707) 2479 367.8 8.3e-101
XP_011516303 (OMIM: 601337) PREDICTED: transcripti ( 687) 2462 365.3 4.4e-100
XP_011526472 (OMIM: 600006) PREDICTED: MHC class I ( 980) 2298 341.9 6.9e-93
XP_011526471 (OMIM: 600006) PREDICTED: MHC class I ( 980) 2298 341.9 6.9e-93
XP_011526469 (OMIM: 600006) PREDICTED: MHC class I (1089) 2298 341.9 7.5e-93
XP_011526468 (OMIM: 600006) PREDICTED: MHC class I (1089) 2298 341.9 7.5e-93
XP_011526467 (OMIM: 600006) PREDICTED: MHC class I (1089) 2298 341.9 7.5e-93
NP_002909 (OMIM: 600006) MHC class II regulatory f ( 979) 2297 341.8 7.6e-93
XP_011526470 (OMIM: 600006) PREDICTED: MHC class I ( 991) 2233 332.6 4.4e-90
XP_006716910 (OMIM: 601337) PREDICTED: transcripti ( 492) 1785 268.3 5.2e-71
XP_016870491 (OMIM: 601337) PREDICTED: transcripti ( 501) 1775 266.8 1.4e-70
NP_001269046 (OMIM: 601337) transcription factor R ( 413) 1082 167.5 9.2e-41
NP_115880 (OMIM: 603958) transcription factor RFX4 ( 641) 574 94.9 1e-18
NP_998759 (OMIM: 603958) transcription factor RFX4 ( 735) 374 66.3 4.9e-10
NP_001193620 (OMIM: 603958) transcription factor R ( 744) 374 66.3 5e-10
XP_011533891 (OMIM: 612659,615710) PREDICTED: DNA- ( 892) 323 59.0 9.1e-08
NP_775831 (OMIM: 612659,615710) DNA-binding protei ( 928) 323 59.0 9.4e-08
XP_016865966 (OMIM: 612659,615710) PREDICTED: DNA- ( 802) 317 58.1 1.5e-07
XP_016877995 (OMIM: 612660) PREDICTED: DNA-binding (1460) 227 45.4 0.0019
XP_005254660 (OMIM: 612660) PREDICTED: DNA-binding (1460) 227 45.4 0.0019
NP_073752 (OMIM: 612660) DNA-binding protein RFX7 (1460) 227 45.4 0.0019
XP_016877996 (OMIM: 612660) PREDICTED: DNA-binding (1363) 219 44.2 0.0039
XP_011520227 (OMIM: 612660) PREDICTED: DNA-binding (1363) 219 44.2 0.0039
XP_016877997 (OMIM: 612660) PREDICTED: DNA-binding (1363) 219 44.2 0.0039
XP_005245463 (OMIM: 209920,601863) PREDICTED: DNA- ( 616) 204 41.9 0.0091
XP_011508149 (OMIM: 209920,601863) PREDICTED: DNA- ( 616) 204 41.9 0.0091
NP_001020774 (OMIM: 209920,601863) DNA-binding pro ( 616) 204 41.9 0.0091
NP_000440 (OMIM: 209920,601863) DNA-binding protei ( 616) 204 41.9 0.0091
XP_011508150 (OMIM: 209920,601863) PREDICTED: DNA- ( 616) 204 41.9 0.0091
XP_011508151 (OMIM: 209920,601863) PREDICTED: DNA- ( 616) 204 41.9 0.0091
XP_005245462 (OMIM: 209920,601863) PREDICTED: DNA- ( 616) 204 41.9 0.0091
XP_011508152 (OMIM: 209920,601863) PREDICTED: DNA- ( 616) 204 41.9 0.0091
>>NP_602309 (OMIM: 142765) DNA-binding protein RFX2 isof (698 aa)
initn: 4661 init1: 4661 opt: 4661 Z-score: 3619.9 bits: 680.3 E(85289): 6.8e-195
Smith-Waterman score: 4661; 99.9% identity (100.0% similar) in 698 aa overlap (1-698:1-698)
10 20 30 40 50 60
pF1KB6 MQNSEGGADSPASVALRPSAAAPPVPASPQRVLVQAASSNPKGAQMQPISLPRVQQVPQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_602 MQNSEGGADSPASVALRPSAAAPPVPASPQRVLVQAASSNPKGAQMQPISLPRVQQVPQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VQPVQHVYPAQVQYVEGGDAVYTNGTIRTAYTYNPEPQMYAPSSTASYFEAPGGAQVTVA
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
NP_602 VQPVQHVYPAQVQYVEGGDAVYTNGAIRTAYTYNPEPQMYAPSSTASYFEAPGGAQVTVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 ASSPPAVPSHSMVGITMDVGGSPIVSSAGAYLIHGGMDSTRHSLAHTSRSSPATLQWLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_602 ASSPPAVPSHSMVGITMDVGGSPIVSSAGAYLIHGGMDSTRHSLAHTSRSSPATLQWLLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 NYETAEGVSLPRSSLYNHYLRHCQEHKLDPVNAASFGKLIRSVFMGLRTRRLGTRGNSKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_602 NYETAEGVSLPRSSLYNHYLRHCQEHKLDPVNAASFGKLIRSVFMGLRTRRLGTRGNSKY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 HYYGIRLKPDSPLNRLQEDTQYMAMRQQPMHQKPRYRPAQKTDSLGDSGSHSGLHSTPEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_602 HYYGIRLKPDSPLNRLQEDTQYMAMRQQPMHQKPRYRPAQKTDSLGDSGSHSGLHSTPEQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 TMAVQSQHHQQYIDVSHVFPEFPAPDLGSFLLQDGVTLHDVKALQLVYRRHCEATVDVVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_602 TMAVQSQHHQQYIDVSHVFPEFPAPDLGSFLLQDGVTLHDVKALQLVYRRHCEATVDVVM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 NLQFHYIEKLWLSFWNSKASSSDGPTSLPASDEDPEGAVLPKDKLISLCQCDPILRWMRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_602 NLQFHYIEKLWLSFWNSKASSSDGPTSLPASDEDPEGAVLPKDKLISLCQCDPILRWMRS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 CDHILYQALVEILIPDVLRPVPSTLTQAIRNFAKSLEGWLTNAMSDFPQQVIQTKVGVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_602 CDHILYQALVEILIPDVLRPVPSTLTQAIRNFAKSLEGWLTNAMSDFPQQVIQTKVGVVS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 AFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWVCQCEESVVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_602 AFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWVCQCEESVVQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 RLEQDFKLTLQQQSSLDQWASWLDSVVTQVLKQHAGSPSFPKAARQFLLKWSFYSSMVIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_602 RLEQDFKLTLQQQSSLDQWASWLDSVVTQVLKQHAGSPSFPKAARQFLLKWSFYSSMVIR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB6 DLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAEATGETPIAVMGEFNDLASLSLTLLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_602 DLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAEATGETPIAVMGEFNDLASLSLTLLDK
610 620 630 640 650 660
670 680 690
pF1KB6 DDMGDEQRGSEAGPDARSLGEPLVKRERSDPNHSLQGI
::::::::::::::::::::::::::::::::::::::
NP_602 DDMGDEQRGSEAGPDARSLGEPLVKRERSDPNHSLQGI
670 680 690
>>XP_016882597 (OMIM: 142765) PREDICTED: DNA-binding pro (653 aa)
initn: 4369 init1: 4369 opt: 4369 Z-score: 3394.3 bits: 638.4 E(85289): 2.5e-182
Smith-Waterman score: 4369; 99.8% identity (100.0% similar) in 653 aa overlap (46-698:1-653)
20 30 40 50 60 70
pF1KB6 LRPSAAAPPVPASPQRVLVQAASSNPKGAQMQPISLPRVQQVPQQVQPVQHVYPAQVQYV
::::::::::::::::::::::::::::::
XP_016 MQPISLPRVQQVPQQVQPVQHVYPAQVQYV
10 20 30
80 90 100 110 120 130
pF1KB6 EGGDAVYTNGTIRTAYTYNPEPQMYAPSSTASYFEAPGGAQVTVAASSPPAVPSHSMVGI
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGGDAVYTNGAIRTAYTYNPEPQMYAPSSTASYFEAPGGAQVTVAASSPPAVPSHSMVGI
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB6 TMDVGGSPIVSSAGAYLIHGGMDSTRHSLAHTSRSSPATLQWLLDNYETAEGVSLPRSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMDVGGSPIVSSAGAYLIHGGMDSTRHSLAHTSRSSPATLQWLLDNYETAEGVSLPRSSL
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB6 YNHYLRHCQEHKLDPVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGIRLKPDSPLNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YNHYLRHCQEHKLDPVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGIRLKPDSPLNR
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB6 LQEDTQYMAMRQQPMHQKPRYRPAQKTDSLGDSGSHSGLHSTPEQTMAVQSQHHQQYIDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQEDTQYMAMRQQPMHQKPRYRPAQKTDSLGDSGSHSGLHSTPEQTMAVQSQHHQQYIDV
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB6 SHVFPEFPAPDLGSFLLQDGVTLHDVKALQLVYRRHCEATVDVVMNLQFHYIEKLWLSFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHVFPEFPAPDLGSFLLQDGVTLHDVKALQLVYRRHCEATVDVVMNLQFHYIEKLWLSFW
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB6 NSKASSSDGPTSLPASDEDPEGAVLPKDKLISLCQCDPILRWMRSCDHILYQALVEILIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSKASSSDGPTSLPASDEDPEGAVLPKDKLISLCQCDPILRWMRSCDHILYQALVEILIP
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB6 DVLRPVPSTLTQAIRNFAKSLEGWLTNAMSDFPQQVIQTKVGVVSAFAQTLRRYTSLNHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVLRPVPSTLTQAIRNFAKSLEGWLTNAMSDFPQQVIQTKVGVVSAFAQTLRRYTSLNHL
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB6 AQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWVCQCEESVVQRLEQDFKLTLQQQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWVCQCEESVVQRLEQDFKLTLQQQSS
460 470 480 490 500 510
560 570 580 590 600 610
pF1KB6 LDQWASWLDSVVTQVLKQHAGSPSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDQWASWLDSVVTQVLKQHAGSPSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHL
520 530 540 550 560 570
620 630 640 650 660 670
pF1KB6 IRLLYDEYMFYLVEHRVAEATGETPIAVMGEFNDLASLSLTLLDKDDMGDEQRGSEAGPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRLLYDEYMFYLVEHRVAEATGETPIAVMGEFNDLASLSLTLLDKDDMGDEQRGSEAGPD
580 590 600 610 620 630
680 690
pF1KB6 ARSLGEPLVKRERSDPNHSLQGI
:::::::::::::::::::::::
XP_016 ARSLGEPLVKRERSDPNHSLQGI
640 650
>>XP_011526473 (OMIM: 142765) PREDICTED: DNA-binding pro (723 aa)
initn: 3518 init1: 3518 opt: 3540 Z-score: 2752.0 bits: 519.7 E(85289): 1.5e-146
Smith-Waterman score: 4601; 96.4% identity (96.5% similar) in 723 aa overlap (1-698:1-723)
10 20 30 40 50 60
pF1KB6 MQNSEGGADSPASVALRPSAAAPPVPASPQRVLVQAASSNPKGAQMQPISLPRVQQVPQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQNSEGGADSPASVALRPSAAAPPVPASPQRVLVQAASSNPKGAQMQPISLPRVQQVPQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VQPVQHVYPAQVQYVEGGDAVYTNGTIRTAYTYNPEPQMYAPSSTASYFEAPGGAQVTVA
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
XP_011 VQPVQHVYPAQVQYVEGGDAVYTNGAIRTAYTYNPEPQMYAPSSTASYFEAPGGAQVTVA
70 80 90 100 110 120
130 140 150 160 170
pF1KB6 ASSPPAVPSHSMVGITMDVGGSPIVSSAGAYLIHGGMDSTRHSLAHTSRSSPATL-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASSPPAVPSHSMVGITMDVGGSPIVSSAGAYLIHGGMDSTRHSLAHTSRSSPATLEMAIE
130 140 150 160 170 180
180 190 200 210
pF1KB6 --------------------QWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKLDPVNAAS
::::::::::::::::::::::::::::::::::::::::
XP_011 NLQKSEGITSHKSGLLNSHLQWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKLDPVNAAS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB6 FGKLIRSVFMGLRTRRLGTRGNSKYHYYGIRLKPDSPLNRLQEDTQYMAMRQQPMHQKPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGKLIRSVFMGLRTRRLGTRGNSKYHYYGIRLKPDSPLNRLQEDTQYMAMRQQPMHQKPR
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB6 YRPAQKTDSLGDSGSHSGLHSTPEQTMAVQSQHHQQYIDVSHVFPEFPAPDLGSFLLQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRPAQKTDSLGDSGSHSGLHSTPEQTMAVQSQHHQQYIDVSHVFPEFPAPDLGSFLLQDG
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB6 VTLHDVKALQLVYRRHCEATVDVVMNLQFHYIEKLWLSFWNSKASSSDGPTSLPASDEDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTLHDVKALQLVYRRHCEATVDVVMNLQFHYIEKLWLSFWNSKASSSDGPTSLPASDEDP
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB6 EGAVLPKDKLISLCQCDPILRWMRSCDHILYQALVEILIPDVLRPVPSTLTQAIRNFAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGAVLPKDKLISLCQCDPILRWMRSCDHILYQALVEILIPDVLRPVPSTLTQAIRNFAKS
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB6 LEGWLTNAMSDFPQQVIQTKVGVVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEGWLTNAMSDFPQQVIQTKVGVVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSD
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB6 LNRVDFANVQEQASWVCQCEESVVQRLEQDFKLTLQQQSSLDQWASWLDSVVTQVLKQHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNRVDFANVQEQASWVCQCEESVVQRLEQDFKLTLQQQSSLDQWASWLDSVVTQVLKQHA
550 560 570 580 590 600
580 590 600 610 620 630
pF1KB6 GSPSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSPSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAEA
610 620 630 640 650 660
640 650 660 670 680 690
pF1KB6 TGETPIAVMGEFNDLASLSLTLLDKDDMGDEQRGSEAGPDARSLGEPLVKRERSDPNHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGETPIAVMGEFNDLASLSLTLLDKDDMGDEQRGSEAGPDARSLGEPLVKRERSDPNHSL
670 680 690 700 710 720
pF1KB6 QGI
:::
XP_011 QGI
>>NP_000626 (OMIM: 142765) DNA-binding protein RFX2 isof (723 aa)
initn: 3518 init1: 3518 opt: 3540 Z-score: 2752.0 bits: 519.7 E(85289): 1.5e-146
Smith-Waterman score: 4601; 96.4% identity (96.5% similar) in 723 aa overlap (1-698:1-723)
10 20 30 40 50 60
pF1KB6 MQNSEGGADSPASVALRPSAAAPPVPASPQRVLVQAASSNPKGAQMQPISLPRVQQVPQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MQNSEGGADSPASVALRPSAAAPPVPASPQRVLVQAASSNPKGAQMQPISLPRVQQVPQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VQPVQHVYPAQVQYVEGGDAVYTNGTIRTAYTYNPEPQMYAPSSTASYFEAPGGAQVTVA
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
NP_000 VQPVQHVYPAQVQYVEGGDAVYTNGAIRTAYTYNPEPQMYAPSSTASYFEAPGGAQVTVA
70 80 90 100 110 120
130 140 150 160 170
pF1KB6 ASSPPAVPSHSMVGITMDVGGSPIVSSAGAYLIHGGMDSTRHSLAHTSRSSPATL-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ASSPPAVPSHSMVGITMDVGGSPIVSSAGAYLIHGGMDSTRHSLAHTSRSSPATLEMAIE
130 140 150 160 170 180
180 190 200 210
pF1KB6 --------------------QWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKLDPVNAAS
::::::::::::::::::::::::::::::::::::::::
NP_000 NLQKSEGITSHKSGLLNSHLQWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKLDPVNAAS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB6 FGKLIRSVFMGLRTRRLGTRGNSKYHYYGIRLKPDSPLNRLQEDTQYMAMRQQPMHQKPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FGKLIRSVFMGLRTRRLGTRGNSKYHYYGIRLKPDSPLNRLQEDTQYMAMRQQPMHQKPR
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB6 YRPAQKTDSLGDSGSHSGLHSTPEQTMAVQSQHHQQYIDVSHVFPEFPAPDLGSFLLQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YRPAQKTDSLGDSGSHSGLHSTPEQTMAVQSQHHQQYIDVSHVFPEFPAPDLGSFLLQDG
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB6 VTLHDVKALQLVYRRHCEATVDVVMNLQFHYIEKLWLSFWNSKASSSDGPTSLPASDEDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VTLHDVKALQLVYRRHCEATVDVVMNLQFHYIEKLWLSFWNSKASSSDGPTSLPASDEDP
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB6 EGAVLPKDKLISLCQCDPILRWMRSCDHILYQALVEILIPDVLRPVPSTLTQAIRNFAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EGAVLPKDKLISLCQCDPILRWMRSCDHILYQALVEILIPDVLRPVPSTLTQAIRNFAKS
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB6 LEGWLTNAMSDFPQQVIQTKVGVVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LEGWLTNAMSDFPQQVIQTKVGVVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSD
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB6 LNRVDFANVQEQASWVCQCEESVVQRLEQDFKLTLQQQSSLDQWASWLDSVVTQVLKQHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LNRVDFANVQEQASWVCQCEESVVQRLEQDFKLTLQQQSSLDQWASWLDSVVTQVLKQHA
550 560 570 580 590 600
580 590 600 610 620 630
pF1KB6 GSPSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GSPSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAEA
610 620 630 640 650 660
640 650 660 670 680 690
pF1KB6 TGETPIAVMGEFNDLASLSLTLLDKDDMGDEQRGSEAGPDARSLGEPLVKRERSDPNHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TGETPIAVMGEFNDLASLSLTLLDKDDMGDEQRGSEAGPDARSLGEPLVKRERSDPNHSL
670 680 690 700 710 720
pF1KB6 QGI
:::
NP_000 QGI
>>XP_016882596 (OMIM: 142765) PREDICTED: DNA-binding pro (678 aa)
initn: 3518 init1: 3518 opt: 3528 Z-score: 2743.1 bits: 518.0 E(85289): 4.7e-146
Smith-Waterman score: 4309; 96.2% identity (96.3% similar) in 678 aa overlap (46-698:1-678)
20 30 40 50 60 70
pF1KB6 LRPSAAAPPVPASPQRVLVQAASSNPKGAQMQPISLPRVQQVPQQVQPVQHVYPAQVQYV
::::::::::::::::::::::::::::::
XP_016 MQPISLPRVQQVPQQVQPVQHVYPAQVQYV
10 20 30
80 90 100 110 120 130
pF1KB6 EGGDAVYTNGTIRTAYTYNPEPQMYAPSSTASYFEAPGGAQVTVAASSPPAVPSHSMVGI
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGGDAVYTNGAIRTAYTYNPEPQMYAPSSTASYFEAPGGAQVTVAASSPPAVPSHSMVGI
40 50 60 70 80 90
140 150 160 170
pF1KB6 TMDVGGSPIVSSAGAYLIHGGMDSTRHSLAHTSRSSPATL--------------------
::::::::::::::::::::::::::::::::::::::::
XP_016 TMDVGGSPIVSSAGAYLIHGGMDSTRHSLAHTSRSSPATLEMAIENLQKSEGITSHKSGL
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB6 -----QWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKLDPVNAASFGKLIRSVFMGLRTR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNSHLQWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKLDPVNAASFGKLIRSVFMGLRTR
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB6 RLGTRGNSKYHYYGIRLKPDSPLNRLQEDTQYMAMRQQPMHQKPRYRPAQKTDSLGDSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLGTRGNSKYHYYGIRLKPDSPLNRLQEDTQYMAMRQQPMHQKPRYRPAQKTDSLGDSGS
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB6 HSGLHSTPEQTMAVQSQHHQQYIDVSHVFPEFPAPDLGSFLLQDGVTLHDVKALQLVYRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSGLHSTPEQTMAVQSQHHQQYIDVSHVFPEFPAPDLGSFLLQDGVTLHDVKALQLVYRR
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB6 HCEATVDVVMNLQFHYIEKLWLSFWNSKASSSDGPTSLPASDEDPEGAVLPKDKLISLCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCEATVDVVMNLQFHYIEKLWLSFWNSKASSSDGPTSLPASDEDPEGAVLPKDKLISLCQ
340 350 360 370 380 390
420 430 440 450 460 470
pF1KB6 CDPILRWMRSCDHILYQALVEILIPDVLRPVPSTLTQAIRNFAKSLEGWLTNAMSDFPQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDPILRWMRSCDHILYQALVEILIPDVLRPVPSTLTQAIRNFAKSLEGWLTNAMSDFPQQ
400 410 420 430 440 450
480 490 500 510 520 530
pF1KB6 VIQTKVGVVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIQTKVGVVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASW
460 470 480 490 500 510
540 550 560 570 580 590
pF1KB6 VCQCEESVVQRLEQDFKLTLQQQSSLDQWASWLDSVVTQVLKQHAGSPSFPKAARQFLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCQCEESVVQRLEQDFKLTLQQQSSLDQWASWLDSVVTQVLKQHAGSPSFPKAARQFLLK
520 530 540 550 560 570
600 610 620 630 640 650
pF1KB6 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAEATGETPIAVMGEFNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAEATGETPIAVMGEFNDL
580 590 600 610 620 630
660 670 680 690
pF1KB6 ASLSLTLLDKDDMGDEQRGSEAGPDARSLGEPLVKRERSDPNHSLQGI
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLSLTLLDKDDMGDEQRGSEAGPDARSLGEPLVKRERSDPNHSLQGI
640 650 660 670
>>XP_011526474 (OMIM: 142765) PREDICTED: DNA-binding pro (687 aa)
initn: 3257 init1: 3257 opt: 3279 Z-score: 2550.3 bits: 482.3 E(85289): 2.6e-135
Smith-Waterman score: 4340; 96.2% identity (96.4% similar) in 685 aa overlap (1-660:1-685)
10 20 30 40 50 60
pF1KB6 MQNSEGGADSPASVALRPSAAAPPVPASPQRVLVQAASSNPKGAQMQPISLPRVQQVPQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQNSEGGADSPASVALRPSAAAPPVPASPQRVLVQAASSNPKGAQMQPISLPRVQQVPQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VQPVQHVYPAQVQYVEGGDAVYTNGTIRTAYTYNPEPQMYAPSSTASYFEAPGGAQVTVA
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
XP_011 VQPVQHVYPAQVQYVEGGDAVYTNGAIRTAYTYNPEPQMYAPSSTASYFEAPGGAQVTVA
70 80 90 100 110 120
130 140 150 160 170
pF1KB6 ASSPPAVPSHSMVGITMDVGGSPIVSSAGAYLIHGGMDSTRHSLAHTSRSSPATL-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASSPPAVPSHSMVGITMDVGGSPIVSSAGAYLIHGGMDSTRHSLAHTSRSSPATLEMAIE
130 140 150 160 170 180
180 190 200 210
pF1KB6 --------------------QWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKLDPVNAAS
::::::::::::::::::::::::::::::::::::::::
XP_011 NLQKSEGITSHKSGLLNSHLQWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKLDPVNAAS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB6 FGKLIRSVFMGLRTRRLGTRGNSKYHYYGIRLKPDSPLNRLQEDTQYMAMRQQPMHQKPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGKLIRSVFMGLRTRRLGTRGNSKYHYYGIRLKPDSPLNRLQEDTQYMAMRQQPMHQKPR
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB6 YRPAQKTDSLGDSGSHSGLHSTPEQTMAVQSQHHQQYIDVSHVFPEFPAPDLGSFLLQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRPAQKTDSLGDSGSHSGLHSTPEQTMAVQSQHHQQYIDVSHVFPEFPAPDLGSFLLQDG
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB6 VTLHDVKALQLVYRRHCEATVDVVMNLQFHYIEKLWLSFWNSKASSSDGPTSLPASDEDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTLHDVKALQLVYRRHCEATVDVVMNLQFHYIEKLWLSFWNSKASSSDGPTSLPASDEDP
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB6 EGAVLPKDKLISLCQCDPILRWMRSCDHILYQALVEILIPDVLRPVPSTLTQAIRNFAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGAVLPKDKLISLCQCDPILRWMRSCDHILYQALVEILIPDVLRPVPSTLTQAIRNFAKS
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB6 LEGWLTNAMSDFPQQVIQTKVGVVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEGWLTNAMSDFPQQVIQTKVGVVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSD
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB6 LNRVDFANVQEQASWVCQCEESVVQRLEQDFKLTLQQQSSLDQWASWLDSVVTQVLKQHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNRVDFANVQEQASWVCQCEESVVQRLEQDFKLTLQQQSSLDQWASWLDSVVTQVLKQHA
550 560 570 580 590 600
580 590 600 610 620 630
pF1KB6 GSPSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSPSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAEA
610 620 630 640 650 660
640 650 660 670 680 690
pF1KB6 TGETPIAVMGEFNDLASLSLTLLDKDDMGDEQRGSEAGPDARSLGEPLVKRERSDPNHSL
:::::::::::::::::::::::::
XP_011 TGETPIAVMGEFNDLASLSLTLLDKGR
670 680
>>XP_016870490 (OMIM: 601337) PREDICTED: transcription f (724 aa)
initn: 2615 init1: 1472 opt: 2891 Z-score: 2249.6 bits: 426.8 E(85289): 1.5e-118
Smith-Waterman score: 2923; 66.7% identity (84.7% similar) in 699 aa overlap (1-690:1-673)
10 20 30 40 50 60
pF1KB6 MQNSEGGADSPASVALRPSAAAPPVPASPQRVLVQAASSNPKGAQMQPISLPRVQQVPQQ
::.:: :.:. ..:.:. :.:. : : .:. :. : .:.: :::: :
XP_016 MQTSETGSDTGSTVTLQTSVASQA--AVPTQVVQQV----P--VQQQ------VQQV-QT
10 20 30 40
70 80 90 100 110
pF1KB6 VQPVQHVYPAQVQYVEGGDAVYTNGTIRTA-YTYNPEPQMYAPSSTASYFEAPGG-AQVT
:: ::::::::::::::.:.:::::.:::. : :. : :::. .. ..::.. :. ::::
XP_016 VQQVQHVYPAQVQYVEGSDTVYTNGAIRTTTYPYT-ETQMYSQNTGGNYFDTQGSSAQVT
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 VAASSPPAVPSHSMVG---ITMDV-GGSPIVSSAGAYLIHGGMDSTRHSLAHTSRSSPAT
...:: ::::: : : : ::. : ::.:.::: ..:... ::..::.:.::::
XP_016 TVVSS------HSMVGTGGIQMGVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPAT
110 120 130 140 150
180 190 200 210 220 230
pF1KB6 LQWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKLDPVNAASFGKLIRSVFMGLRTRRLGT
:::::::::::::::::::.::::::::::::::::::::::::::::.:::::::::::
XP_016 LQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRRLGT
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB6 RGNSKYHYYGIRLKPDSPLNRLQEDTQYMAMRQQPMHQKPRYRPAQKTDSLGDSGSHSGL
::::::::::::.:::::::::::: ::::::::::.:: ::.: ::.:...:. . ::
XP_016 RGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTGSGQ
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB6 HS--TPEQTMAVQSQHHQQYIDVSHVFPEFPAPDLGSFLLQDGVTLHDVKALQLVYRRHC
.. . :::. .:::::::..:.:...::: ...: : ::.:..:.:.:: .::.::
XP_016 QTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISS--LPDGTTFEDIKSLQSLYREHC
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB6 EATVDVVMNLQFHYIEKLWLSFWN-SKASSSDGPTSLPASDEDPEGAVLPKDKLISLCQC
:: .:::.:::: ::::: .:: : .. .:: : .:. . . ::: :::.::.
XP_016 EAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCKH
340 350 360 370 380 390
420 430 440 450 460 470
pF1KB6 DPILRWMRSCDHILYQALVEILIPDVLRPVPSTLTQAIRNFAKSLEGWLTNAMSDFPQQV
. ::.:: .::: .:::::::::::::::.::.::::::::::::::::.:::...::..
XP_016 ESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQRM
400 410 420 430 440 450
480 490 500 510 520 530
pF1KB6 IQTKVGVVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWV
:::::..:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWV
460 470 480 490 500 510
540 550 560 570 580 590
pF1KB6 CQCEESVVQRLEQDFKLTLQQQSSLDQWASWLDSVVTQVLKQHAGSPSFPKAARQFLLKW
:::....::::: :::.::::::.:.:::.:::.:. :.:: . : ::::::::::::::
XP_016 CQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLKW
520 530 540 550 560 570
600 610 620 630 640 650
pF1KB6 SFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAEATGETPIAVMGEFNDLA
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::.::
XP_016 SFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGEFGDLN
580 590 600 610 620 630
660 670 680 690
pF1KB6 SLSLTLLDKDDMGDEQRGSEAGPDARSLGEPLVKRERSDPNHSLQGI
..: ::::. :.: . :: . . .:: .:::...
XP_016 AVSPGNLDKDE-GSEVE-SEMDEELDDSSEPQAKREKTELSQAFPVGCMQPVLETGVQPS
640 650 660 670 680 690
XP_016 LLNPIHSEHIVTSTQTIRQCSATGNTYTAV
700 710 720
>>XP_011516302 (OMIM: 601337) PREDICTED: transcription f (745 aa)
initn: 2574 init1: 1431 opt: 2820 Z-score: 2194.4 bits: 416.6 E(85289): 1.7e-115
Smith-Waterman score: 2871; 64.7% identity (82.2% similar) in 720 aa overlap (1-690:1-694)
10 20 30 40 50 60
pF1KB6 MQNSEGGADSPASVALRPSAAAPPVPASPQRVLVQAASSNPKGAQMQPISLPRVQQVPQQ
::.:: :.:. ..:.:. :.:. : : .:. :. : .:.: :::: :
XP_011 MQTSETGSDTGSTVTLQTSVASQA--AVPTQVVQQV----P--VQQQ------VQQV-QT
10 20 30 40
70 80 90 100 110
pF1KB6 VQPVQHVYPAQVQYVEGGDAVYTNGTIRTA-YTYNPEPQMYAPSSTASYFEAPGG-AQVT
:: ::::::::::::::.:.:::::.:::. : :. : :::. .. ..::.. :. ::::
XP_011 VQQVQHVYPAQVQYVEGSDTVYTNGAIRTTTYPYT-ETQMYSQNTGGNYFDTQGSSAQVT
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 VAASSPPAVPSHSMVG---ITMDV-GGSPIVSSAGAYLIHGGMDSTRHSLAHTSRSSPAT
...:: ::::: : : : ::. : ::.:.::: ..:... ::..::.:.::::
XP_011 TVVSS------HSMVGTGGIQMGVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPAT
110 120 130 140 150
180 190 200 210 220 230
pF1KB6 LQWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKLDPVNAASFGKLIRSVFMGLRTRRLGT
:::::::::::::::::::.::::::::::::::::::::::::::::.:::::::::::
XP_011 LQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRRLGT
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB6 RGNSKYHYYGIRLKPDSPLNRLQEDTQYMAMRQQPMHQKPRYRPAQKTDSLGDSGSHSGL
::::::::::::.:::::::::::: ::::::::::.:: ::.: ::.:...:. . ::
XP_011 RGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTGSGQ
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB6 HS--TPEQTMAVQSQHHQQYIDVSHVFPEFPAPDLGSFLLQDGVTLHDVKALQLVYRRHC
.. . :::. .:::::::..:.:...::: ...: : ::.:..:.:.:: .::.::
XP_011 QTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISS--LPDGTTFEDIKSLQSLYREHC
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB6 EATVDVVMNLQFHYIEKLWLSFWN-SKASSSDGPTSLPASDEDPEGAVLPKDKLISLCQC
:: .:::.:::: ::::: .:: : .. .:: : .:. . . ::: :::.::.
XP_011 EAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCKH
340 350 360 370 380 390
420 430 440 450 460 470
pF1KB6 DPILRWMRSCDHILYQALVEILIPDVLRPVPSTLTQAIRNFAKSLEGWLTNAMSDFPQQV
. ::.:: .::: .:::::::::::::::.::.::::::::::::::::.:::...::..
XP_011 ESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQRM
400 410 420 430 440 450
480 490 500 510 520 530
pF1KB6 IQTKVGVVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWV
:::::..:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWV
460 470 480 490 500 510
540 550 560 570 580 590
pF1KB6 CQCEESVVQRLEQDFKLTLQQQSSLDQWASWLDSVVTQVLKQHAGSPSFPKAARQFLLKW
:::....::::: :::.::::::.:.:::.:::.:. :.:: . : ::::::::::::::
XP_011 CQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLKW
520 530 540 550 560 570
600 610 620 630 640
pF1KB6 SFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAEATGETPIAVMGE-----
::::::::::::::::::::::::::::::::::::::::::.::::::::::::
XP_011 SFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGETNLVD
580 590 600 610 620 630
650 660 670 680 690
pF1KB6 ----------------FNDLASLSLTLLDKDDMGDEQRGSEAGPDARSLGEPLVKRERSD
:.:: ..: ::::. :.: . :: . . .:: .:::...
XP_011 EKNTPIMELFISKLLNFGDLNAVSPGNLDKDE-GSEVE-SEMDEELDDSSEPQAKREKTE
640 650 660 670 680 690
pF1KB6 PNHSLQGI
XP_011 LSQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV
700 710 720 730 740
>>NP_001269045 (OMIM: 601337) transcription factor RFX3 (749 aa)
initn: 2618 init1: 1464 opt: 2555 Z-score: 1989.3 bits: 378.7 E(85289): 4.6e-104
Smith-Waterman score: 2863; 64.4% identity (81.8% similar) in 724 aa overlap (1-690:1-698)
10 20 30 40 50 60
pF1KB6 MQNSEGGADSPASVALRPSAAAPPVPASPQRVLVQAASSNPKGAQMQPISLPRVQQVPQQ
::.:: :.:. ..:.:. :.:. : : .:. :. : .:.: :::: :
NP_001 MQTSETGSDTGSTVTLQTSVASQA--AVPTQVVQQV----P--VQQQ------VQQV-QT
10 20 30 40
70 80 90 100 110
pF1KB6 VQPVQHVYPAQVQYVEGGDAVYTNGTIRTA-YTYNPEPQMYAPSSTASYFEAPGG-AQVT
:: ::::::::::::::.:.:::::.:::. : :. : :::. .. ..::.. :. ::::
NP_001 VQQVQHVYPAQVQYVEGSDTVYTNGAIRTTTYPYT-ETQMYSQNTGGNYFDTQGSSAQVT
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 VAASSPPAVPSHSMVG---ITMDV-GGSPIVSSAGAYLIHGGMDSTRHSLAHTSRSSPAT
...:: ::::: : : : ::. : ::.:.::: ..:... ::..::.:.::::
NP_001 TVVSS------HSMVGTGGIQMGVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPAT
110 120 130 140 150
180 190 200
pF1KB6 -------------------------LQWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKLD
:::::::::::::::::::.:::::::::::::::
NP_001 IEMAIETLQKSDGLSTHRSSLLNSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLD
160 170 180 190 200 210
210 220 230 240 250 260
pF1KB6 PVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGIRLKPDSPLNRLQEDTQYMAMRQQP
:::::::::::::.:::::::::::::::::::::::.:::::::::::: :::::::::
NP_001 PVNAASFGKLIRSIFMGLRTRRLGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQP
220 230 240 250 260 270
270 280 290 300 310 320
pF1KB6 MHQKPRYRPAQKTDSLGDSGSHSGLHS--TPEQTMAVQSQHHQQYIDVSHVFPEFPAPDL
:.:: ::.: ::.:...:. . :: .. . :::. .:::::::..:.:...::: ..
NP_001 MQQKQRYKPMQKVDGVADGFTGSGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEI
280 290 300 310 320 330
330 340 350 360 370 380
pF1KB6 GSFLLQDGVTLHDVKALQLVYRRHCEATVDVVMNLQFHYIEKLWLSFWN-SKASSSDGPT
.: : ::.:..:.:.:: .::.:::: .:::.:::: ::::: .:: : .. .:: :
NP_001 SS--LPDGTTFEDIKSLQSLYREHCEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTT
340 350 360 370 380 390
390 400 410 420 430 440
pF1KB6 SLPASDEDPEGAVLPKDKLISLCQCDPILRWMRSCDHILYQALVEILIPDVLRPVPSTLT
.:. . . ::: :::.::. . ::.:: .::: .:::::::::::::::.::.::
NP_001 ITESSNLSEIESRLPKAKLITLCKHESILKWMCNCDHGMYQALVEILIPDVLRPIPSALT
400 410 420 430 440 450
450 460 470 480 490 500
pF1KB6 QAIRNFAKSLEGWLTNAMSDFPQQVIQTKVGVVSAFAQTLRRYTSLNHLAQAARAVLQNT
::::::::::::::.:::...::..:::::..::::::::::::::::::::::::::::
NP_001 QAIRNFAKSLEGWLSNAMNNIPQRMIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNT
460 470 480 490 500 510
510 520 530 540 550 560
pF1KB6 SQINQMLSDLNRVDFANVQEQASWVCQCEESVVQRLEQDFKLTLQQQSSLDQWASWLDSV
::::::::::::::::::::::::::::....::::: :::.::::::.:.:::.:::.:
NP_001 SQINQMLSDLNRVDFANVQEQASWVCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNV
520 530 540 550 560 570
570 580 590 600 610 620
pF1KB6 VTQVLKQHAGSPSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFY
. :.:: . : :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMQALKPYEGRPSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFY
580 590 600 610 620 630
630 640 650 660 670 680
pF1KB6 LVEHRVAEATGETPIAVMGEFNDLASLSLTLLDKDDMGDEQRGSEAGPDARSLGEPLVKR
:::::::.:::::::::::::.:: ..: ::::. :.: . :: . . .:: .::
NP_001 LVEHRVAQATGETPIAVMGEFGDLNAVSPGNLDKDE-GSEVE-SEMDEELDDSSEPQAKR
640 650 660 670 680 690
690
pF1KB6 ERSDPNHSLQGI
:...
NP_001 EKTELSQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV
700 710 720 730 740
>>NP_602304 (OMIM: 601337) transcription factor RFX3 iso (749 aa)
initn: 2618 init1: 1464 opt: 2555 Z-score: 1989.3 bits: 378.7 E(85289): 4.6e-104
Smith-Waterman score: 2863; 64.4% identity (81.8% similar) in 724 aa overlap (1-690:1-698)
10 20 30 40 50 60
pF1KB6 MQNSEGGADSPASVALRPSAAAPPVPASPQRVLVQAASSNPKGAQMQPISLPRVQQVPQQ
::.:: :.:. ..:.:. :.:. : : .:. :. : .:.: :::: :
NP_602 MQTSETGSDTGSTVTLQTSVASQA--AVPTQVVQQV----P--VQQQ------VQQV-QT
10 20 30 40
70 80 90 100 110
pF1KB6 VQPVQHVYPAQVQYVEGGDAVYTNGTIRTA-YTYNPEPQMYAPSSTASYFEAPGG-AQVT
:: ::::::::::::::.:.:::::.:::. : :. : :::. .. ..::.. :. ::::
NP_602 VQQVQHVYPAQVQYVEGSDTVYTNGAIRTTTYPYT-ETQMYSQNTGGNYFDTQGSSAQVT
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 VAASSPPAVPSHSMVG---ITMDV-GGSPIVSSAGAYLIHGGMDSTRHSLAHTSRSSPAT
...:: ::::: : : : ::. : ::.:.::: ..:... ::..::.:.::::
NP_602 TVVSS------HSMVGTGGIQMGVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPAT
110 120 130 140 150
180 190 200
pF1KB6 -------------------------LQWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKLD
:::::::::::::::::::.:::::::::::::::
NP_602 IEMAIETLQKSDGLSTHRSSLLNSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLD
160 170 180 190 200 210
210 220 230 240 250 260
pF1KB6 PVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGIRLKPDSPLNRLQEDTQYMAMRQQP
:::::::::::::.:::::::::::::::::::::::.:::::::::::: :::::::::
NP_602 PVNAASFGKLIRSIFMGLRTRRLGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQP
220 230 240 250 260 270
270 280 290 300 310 320
pF1KB6 MHQKPRYRPAQKTDSLGDSGSHSGLHS--TPEQTMAVQSQHHQQYIDVSHVFPEFPAPDL
:.:: ::.: ::.:...:. . :: .. . :::. .:::::::..:.:...::: ..
NP_602 MQQKQRYKPMQKVDGVADGFTGSGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEI
280 290 300 310 320 330
330 340 350 360 370 380
pF1KB6 GSFLLQDGVTLHDVKALQLVYRRHCEATVDVVMNLQFHYIEKLWLSFWN-SKASSSDGPT
.: : ::.:..:.:.:: .::.:::: .:::.:::: ::::: .:: : .. .:: :
NP_602 SS--LPDGTTFEDIKSLQSLYREHCEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTT
340 350 360 370 380 390
390 400 410 420 430 440
pF1KB6 SLPASDEDPEGAVLPKDKLISLCQCDPILRWMRSCDHILYQALVEILIPDVLRPVPSTLT
.:. . . ::: :::.::. . ::.:: .::: .:::::::::::::::.::.::
NP_602 ITESSNLSEIESRLPKAKLITLCKHESILKWMCNCDHGMYQALVEILIPDVLRPIPSALT
400 410 420 430 440 450
450 460 470 480 490 500
pF1KB6 QAIRNFAKSLEGWLTNAMSDFPQQVIQTKVGVVSAFAQTLRRYTSLNHLAQAARAVLQNT
::::::::::::::.:::...::..:::::..::::::::::::::::::::::::::::
NP_602 QAIRNFAKSLEGWLSNAMNNIPQRMIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNT
460 470 480 490 500 510
510 520 530 540 550 560
pF1KB6 SQINQMLSDLNRVDFANVQEQASWVCQCEESVVQRLEQDFKLTLQQQSSLDQWASWLDSV
::::::::::::::::::::::::::::....::::: :::.::::::.:.:::.:::.:
NP_602 SQINQMLSDLNRVDFANVQEQASWVCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNV
520 530 540 550 560 570
570 580 590 600 610 620
pF1KB6 VTQVLKQHAGSPSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFY
. :.:: . : :::::::::::::::::::::::::::::::::::::::::::::::::
NP_602 MMQALKPYEGRPSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFY
580 590 600 610 620 630
630 640 650 660 670 680
pF1KB6 LVEHRVAEATGETPIAVMGEFNDLASLSLTLLDKDDMGDEQRGSEAGPDARSLGEPLVKR
:::::::.:::::::::::::.:: ..: ::::. :.: . :: . . .:: .::
NP_602 LVEHRVAQATGETPIAVMGEFGDLNAVSPGNLDKDE-GSEVE-SEMDEELDDSSEPQAKR
640 650 660 670 680 690
690
pF1KB6 ERSDPNHSLQGI
:...
NP_602 EKTELSQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV
700 710 720 730 740
698 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 13:51:11 2016 done: Sat Nov 5 13:51:12 2016
Total Scan time: 9.510 Total Display time: 0.190
Function used was FASTA [36.3.4 Apr, 2011]