Result of FASTA (omim) for
pFN21AB6167
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6167, 649 aa
1>>>pF1KB6167 649 - 649 aa - 649 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0513+/-0.000467; mu= 15.8759+/- 0.029
mean_var=85.4507+/-16.593, 0's: 0 Z-trim(110.4): 115 B-trim: 332 in 1/48
Lambda= 0.138745
statistics sampled from 18648 (18770) to 18648 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.551), E-opt: 0.2 (0.22), width: 16
Scan time: 9.390
The best scores are: opt bits E(85289)
NP_116559 (OMIM: 600537) ATP-dependent DNA helicas ( 649) 4277 866.8 0
NP_002898 (OMIM: 600537) ATP-dependent DNA helicas ( 649) 4277 866.8 0
XP_005253518 (OMIM: 600537) PREDICTED: ATP-depende ( 649) 4277 866.8 0
XP_005253520 (OMIM: 600537) PREDICTED: ATP-depende ( 649) 4277 866.8 0
XP_005253521 (OMIM: 600537) PREDICTED: ATP-depende ( 649) 4277 866.8 0
XP_005253519 (OMIM: 600537) PREDICTED: ATP-depende ( 649) 4277 866.8 0
XP_011520183 (OMIM: 210900,604610) PREDICTED: Bloo ( 979) 1156 242.2 6.8e-63
NP_001274177 (OMIM: 210900,604610) Bloom syndrome (1042) 1156 242.2 7.2e-63
NP_001274176 (OMIM: 210900,604610) Bloom syndrome (1286) 1156 242.2 8.6e-63
NP_001274175 (OMIM: 210900,604610) Bloom syndrome (1417) 1156 242.3 9.3e-63
NP_000048 (OMIM: 210900,604610) Bloom syndrome pro (1417) 1156 242.3 9.3e-63
XP_006720695 (OMIM: 210900,604610) PREDICTED: Bloo ( 763) 1142 239.3 3.9e-62
NP_001003716 (OMIM: 603781) ATP-dependent DNA heli ( 410) 882 187.1 1.1e-46
NP_001003715 (OMIM: 603781) ATP-dependent DNA heli ( 435) 882 187.1 1.1e-46
XP_016880833 (OMIM: 603781) PREDICTED: ATP-depende ( 435) 882 187.1 1.1e-46
XP_005257880 (OMIM: 603781) PREDICTED: ATP-depende ( 549) 882 187.2 1.4e-46
NP_004250 (OMIM: 603781) ATP-dependent DNA helicas ( 991) 882 187.3 2.2e-46
XP_016880832 (OMIM: 603781) PREDICTED: ATP-depende ( 991) 882 187.3 2.2e-46
XP_005257875 (OMIM: 603781) PREDICTED: ATP-depende (1012) 882 187.3 2.3e-46
XP_011523784 (OMIM: 603781) PREDICTED: ATP-depende (1012) 882 187.3 2.3e-46
XP_011542941 (OMIM: 277700,604611) PREDICTED: Wern (1405) 841 179.2 8.8e-44
NP_000544 (OMIM: 277700,604611) Werner syndrome AT (1432) 841 179.2 9e-44
XP_011542942 (OMIM: 277700,604611) PREDICTED: Wern ( 899) 778 166.5 3.8e-40
XP_011520184 (OMIM: 210900,604610) PREDICTED: Bloo ( 907) 583 127.5 2.2e-28
XP_011515686 (OMIM: 218600,266280,268400,603780) P (1142) 386 88.1 1.9e-16
XP_016869488 (OMIM: 218600,266280,268400,603780) P (1224) 386 88.1 2.1e-16
XP_016869486 (OMIM: 218600,266280,268400,603780) P (1254) 386 88.1 2.1e-16
XP_016869490 (OMIM: 218600,266280,268400,603780) P ( 911) 254 61.6 1.4e-08
XP_016869489 (OMIM: 218600,266280,268400,603780) P ( 941) 254 61.6 1.5e-08
NP_004251 (OMIM: 218600,266280,268400,603780) ATP- (1208) 254 61.7 1.8e-08
XP_016869487 (OMIM: 218600,266280,268400,603780) P (1238) 254 61.7 1.9e-08
XP_016869485 (OMIM: 218600,266280,268400,603780) P (1263) 254 61.7 1.9e-08
XP_016869484 (OMIM: 218600,266280,268400,603780) P (1265) 254 61.7 1.9e-08
XP_016869483 (OMIM: 218600,266280,268400,603780) P (1288) 254 61.7 1.9e-08
XP_016869482 (OMIM: 218600,266280,268400,603780) P (1290) 254 61.7 1.9e-08
XP_016869481 (OMIM: 218600,266280,268400,603780) P (1295) 254 61.7 1.9e-08
XP_016869480 (OMIM: 218600,266280,268400,603780) P (1320) 254 61.7 2e-08
XP_016866492 (OMIM: 606286) PREDICTED: probable AT ( 439) 212 53.0 2.7e-06
XP_011534230 (OMIM: 606286) PREDICTED: probable AT ( 529) 212 53.1 3.1e-06
XP_011534229 (OMIM: 606286) PREDICTED: probable AT ( 529) 212 53.1 3.1e-06
XP_011534228 (OMIM: 606286) PREDICTED: probable AT ( 604) 212 53.1 3.5e-06
NP_061135 (OMIM: 606286) probable ATP-dependent RN ( 648) 212 53.1 3.7e-06
NP_001243839 (OMIM: 606357) nucleolar RNA helicase ( 715) 209 52.5 6.1e-06
NP_004719 (OMIM: 606357) nucleolar RNA helicase 2 ( 783) 209 52.6 6.5e-06
NP_055555 (OMIM: 268305,608546) eukaryotic initiat ( 411) 203 51.2 8.7e-06
NP_006377 (OMIM: 608469) probable ATP-dependent RN ( 729) 206 51.9 9.3e-06
NP_001091974 (OMIM: 608469) probable ATP-dependent ( 731) 206 51.9 9.4e-06
NP_057439 (OMIM: 615428) probable ATP-dependent RN ( 455) 200 50.6 1.4e-05
NP_060365 (OMIM: 616621) probable ATP-dependent RN ( 796) 198 50.4 3e-05
NP_001307525 (OMIM: 180630) probable ATP-dependent ( 614) 194 49.5 4.3e-05
>>NP_116559 (OMIM: 600537) ATP-dependent DNA helicase Q1 (649 aa)
initn: 4277 init1: 4277 opt: 4277 Z-score: 4629.0 bits: 866.8 E(85289): 0
Smith-Waterman score: 4277; 100.0% identity (100.0% similar) in 649 aa overlap (1-649:1-649)
10 20 30 40 50 60
pF1KB6 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
550 560 570 580 590 600
610 620 630 640
pF1KB6 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
610 620 630 640
>>NP_002898 (OMIM: 600537) ATP-dependent DNA helicase Q1 (649 aa)
initn: 4277 init1: 4277 opt: 4277 Z-score: 4629.0 bits: 866.8 E(85289): 0
Smith-Waterman score: 4277; 100.0% identity (100.0% similar) in 649 aa overlap (1-649:1-649)
10 20 30 40 50 60
pF1KB6 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
550 560 570 580 590 600
610 620 630 640
pF1KB6 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
610 620 630 640
>>XP_005253518 (OMIM: 600537) PREDICTED: ATP-dependent D (649 aa)
initn: 4277 init1: 4277 opt: 4277 Z-score: 4629.0 bits: 866.8 E(85289): 0
Smith-Waterman score: 4277; 100.0% identity (100.0% similar) in 649 aa overlap (1-649:1-649)
10 20 30 40 50 60
pF1KB6 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
550 560 570 580 590 600
610 620 630 640
pF1KB6 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
610 620 630 640
>>XP_005253520 (OMIM: 600537) PREDICTED: ATP-dependent D (649 aa)
initn: 4277 init1: 4277 opt: 4277 Z-score: 4629.0 bits: 866.8 E(85289): 0
Smith-Waterman score: 4277; 100.0% identity (100.0% similar) in 649 aa overlap (1-649:1-649)
10 20 30 40 50 60
pF1KB6 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
550 560 570 580 590 600
610 620 630 640
pF1KB6 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
610 620 630 640
>>XP_005253521 (OMIM: 600537) PREDICTED: ATP-dependent D (649 aa)
initn: 4277 init1: 4277 opt: 4277 Z-score: 4629.0 bits: 866.8 E(85289): 0
Smith-Waterman score: 4277; 100.0% identity (100.0% similar) in 649 aa overlap (1-649:1-649)
10 20 30 40 50 60
pF1KB6 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
550 560 570 580 590 600
610 620 630 640
pF1KB6 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
610 620 630 640
>>XP_005253519 (OMIM: 600537) PREDICTED: ATP-dependent D (649 aa)
initn: 4277 init1: 4277 opt: 4277 Z-score: 4629.0 bits: 866.8 E(85289): 0
Smith-Waterman score: 4277; 100.0% identity (100.0% similar) in 649 aa overlap (1-649:1-649)
10 20 30 40 50 60
pF1KB6 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
550 560 570 580 590 600
610 620 630 640
pF1KB6 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
610 620 630 640
>>XP_011520183 (OMIM: 210900,604610) PREDICTED: Bloom sy (979 aa)
initn: 1215 init1: 632 opt: 1156 Z-score: 1250.1 bits: 242.2 E(85289): 6.8e-63
Smith-Waterman score: 1265; 38.1% identity (69.5% similar) in 567 aa overlap (73-604:211-772)
50 60 70 80 90 100
pF1KB6 TKKIKQCLEDSDAGASNEYDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINV
:: . .. :... : :..:: :::.::.
XP_011 FSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINA
190 200 210 220 230 240
110 120 130 140 150 160
pF1KB6 TMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLN
.. :.. :..::::::::::::::: : : :.:: :: ::. ::.. : .: : ::.:.
XP_011 ALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLT
250 260 270 280 290 300
170 180 190 200 210 220
pF1KB6 ASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVH
.... .. .. .. .:. .::.::::::: :. ..: ::. :: . ..:...::.:
XP_011 GDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAH
310 320 330 340 350 360
230 240 250 260 270 280
pF1KB6 CCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFN
: :::::::: ::: ...:...::.. ...:::::. .: : : : . .:. :::
XP_011 CVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFN
370 380 390 400 410 420
290 300 310 320 330 340
pF1KB6 RPNL-YYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHA
: :: :: . .::... : : .. : .. .::::::.:... . .. .:: :. :
XP_011 RHNLKYYVLPKKPKKVA-F--DCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAA
430 440 450 460 470
350 360 370 380 390 400
pF1KB6 GAYHANLEPEDKTTVHRKW-SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQ
::::.: . :..:: . . ::. ::.:::::::::::::::: :. ::.:.:::
XP_011 LAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQ
480 490 500 510 520 530
410 420 430 440 450
pF1KB6 ESGRAGRDDMKADCILYYGFGDIFRISSMVVMENVGQQK--------LYEMVSYCQNISK
:::::::: . :.:.: . :. :.. ...::. :... :: :: ::.::..
XP_011 ESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITE
540 550 560 570 580 590
460 470 480 490 500
pF1KB6 CRRVLMAQHFDEV-WNSEACNKM----CDNCCKDSAFERKNITEYCRDLIKILKQAEELN
:::. . .: : .: . :.: :::::: . .. ...:. ....... : . .
XP_011 CRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFV-QEHSSS
600 610 620 630 640 650
510 520 530 540 550
pF1KB6 EKLTPLK------------LIDSWMGKGAAKLRVAGVVAP--TLPREDLEKIIAHFLIQQ
. . .: :.: ..:. .::.. .:. . . :.. :... ......
XP_011 QGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQ-SGIFGKGSAYSRHNAERLFKKLILDK
660 670 680 690 700 710
560 570 580 590 600
pF1KB6 YLKEDYSFTAY-ATISYLKIGPKAN-LLNNEAHAITMQVTKST----QNSFRAESSQTCH
: :: ..: .:.:. .: ::. .::.. .. :.. .:. :... :. ::
XP_011 ILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREE
720 730 740 750 760 770
610 620 630 640
pF1KB6 SEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
XP_011 MVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEK
780 790 800 810 820 830
>>NP_001274177 (OMIM: 210900,604610) Bloom syndrome prot (1042 aa)
initn: 1215 init1: 632 opt: 1156 Z-score: 1249.7 bits: 242.2 E(85289): 7.2e-63
Smith-Waterman score: 1265; 38.1% identity (69.5% similar) in 567 aa overlap (73-604:274-835)
50 60 70 80 90 100
pF1KB6 TKKIKQCLEDSDAGASNEYDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINV
:: . .. :... : :..:: :::.::.
NP_001 FSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINA
250 260 270 280 290 300
110 120 130 140 150 160
pF1KB6 TMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLN
.. :.. :..::::::::::::::: : : :.:: :: ::. ::.. : .: : ::.:.
NP_001 ALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLT
310 320 330 340 350 360
170 180 190 200 210 220
pF1KB6 ASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVH
.... .. .. .. .:. .::.::::::: :. ..: ::. :: . ..:...::.:
NP_001 GDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAH
370 380 390 400 410 420
230 240 250 260 270 280
pF1KB6 CCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFN
: :::::::: ::: ...:...::.. ...:::::. .: : : : . .:. :::
NP_001 CVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFN
430 440 450 460 470 480
290 300 310 320 330 340
pF1KB6 RPNL-YYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHA
: :: :: . .::... : : .. : .. .::::::.:... . .. .:: :. :
NP_001 RHNLKYYVLPKKPKKVA-F--DCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAA
490 500 510 520 530 540
350 360 370 380 390 400
pF1KB6 GAYHANLEPEDKTTVHRKW-SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQ
::::.: . :..:: . . ::. ::.:::::::::::::::: :. ::.:.:::
NP_001 LAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQ
550 560 570 580 590 600
410 420 430 440 450
pF1KB6 ESGRAGRDDMKADCILYYGFGDIFRISSMVVMENVGQQK--------LYEMVSYCQNISK
:::::::: . :.:.: . :. :.. ...::. :... :: :: ::.::..
NP_001 ESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITE
610 620 630 640 650 660
460 470 480 490 500
pF1KB6 CRRVLMAQHFDEV-WNSEACNKM----CDNCCKDSAFERKNITEYCRDLIKILKQAEELN
:::. . .: : .: . :.: :::::: . .. ...:. ....... : . .
NP_001 CRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFV-QEHSSS
670 680 690 700 710
510 520 530 540 550
pF1KB6 EKLTPLK------------LIDSWMGKGAAKLRVAGVVAP--TLPREDLEKIIAHFLIQQ
. . .: :.: ..:. .::.. .:. . . :.. :... ......
NP_001 QGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQ-SGIFGKGSAYSRHNAERLFKKLILDK
720 730 740 750 760 770
560 570 580 590 600
pF1KB6 YLKEDYSFTAY-ATISYLKIGPKAN-LLNNEAHAITMQVTKST----QNSFRAESSQTCH
: :: ..: .:.:. .: ::. .::.. .. :.. .:. :... :. ::
NP_001 ILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREE
780 790 800 810 820 830
610 620 630 640
pF1KB6 SEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
NP_001 MVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEK
840 850 860 870 880 890
>>NP_001274176 (OMIM: 210900,604610) Bloom syndrome prot (1286 aa)
initn: 1215 init1: 632 opt: 1156 Z-score: 1248.3 bits: 242.2 E(85289): 8.6e-63
Smith-Waterman score: 1210; 42.5% identity (72.4% similar) in 445 aa overlap (73-502:649-1090)
50 60 70 80 90 100
pF1KB6 TKKIKQCLEDSDAGASNEYDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINV
:: . .. :... : :..:: :::.::.
NP_001 FSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINA
620 630 640 650 660 670
110 120 130 140 150 160
pF1KB6 TMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLN
.. :.. :..::::::::::::::: : : :.:: :: ::. ::.. : .: : ::.:.
NP_001 ALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLT
680 690 700 710 720 730
170 180 190 200 210 220
pF1KB6 ASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVH
.... .. .. .. .:. .::.::::::: :. ..: ::. :: . ..:...::.:
NP_001 GDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAH
740 750 760 770 780 790
230 240 250 260 270 280
pF1KB6 CCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFN
: :::::::: ::: ...:...::.. ...:::::. .: : : : . .:. :::
NP_001 CVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFN
800 810 820 830 840 850
290 300 310 320 330 340
pF1KB6 RPNL-YYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHA
: :: :: . .::... : : .. : .. .::::::.:... . .. .:: :. :
NP_001 RHNLKYYVLPKKPKKVA-F--DCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAA
860 870 880 890 900 910
350 360 370 380 390 400
pF1KB6 GAYHANLEPEDKTTVHRKW-SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQ
::::.: . :..:: . . ::. ::.:::::::::::::::: :. ::.:.:::
NP_001 LAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQ
920 930 940 950 960 970
410 420 430 440 450
pF1KB6 ESGRAGRDDMKADCILYYGFGDIFRISSMVVMENVGQQK--------LYEMVSYCQNISK
:::::::: . :.:.: . :. :.. ...::. :... :: :: ::.::..
NP_001 ESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITE
980 990 1000 1010 1020 1030
460 470 480 490 500
pF1KB6 CRRVLMAQHFDEV-WNSEACNKM----CDNCCKDSAFERKNITEYCRDLIKILKQAEELN
:::. . .: : .: . :.: :::::: . .. ...:. .........
NP_001 CRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQ
1040 1050 1060 1070 1080 1090
510 520 530 540 550 560
pF1KB6 EKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPREDLEKIIAHFLIQQYLKEDYSFTAYATI
NP_001 GMRNIKHVGPSGRFTMNMLVDIFLESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYS
1100 1110 1120 1130 1140 1150
>>NP_001274175 (OMIM: 210900,604610) Bloom syndrome prot (1417 aa)
initn: 1215 init1: 632 opt: 1156 Z-score: 1247.7 bits: 242.3 E(85289): 9.3e-63
Smith-Waterman score: 1265; 38.1% identity (69.5% similar) in 567 aa overlap (73-604:649-1210)
50 60 70 80 90 100
pF1KB6 TKKIKQCLEDSDAGASNEYDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINV
:: . .. :... : :..:: :::.::.
NP_001 FSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINA
620 630 640 650 660 670
110 120 130 140 150 160
pF1KB6 TMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLN
.. :.. :..::::::::::::::: : : :.:: :: ::. ::.. : .: : ::.:.
NP_001 ALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLT
680 690 700 710 720 730
170 180 190 200 210 220
pF1KB6 ASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVH
.... .. .. .. .:. .::.::::::: :. ..: ::. :: . ..:...::.:
NP_001 GDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAH
740 750 760 770 780 790
230 240 250 260 270 280
pF1KB6 CCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFN
: :::::::: ::: ...:...::.. ...:::::. .: : : : . .:. :::
NP_001 CVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFN
800 810 820 830 840 850
290 300 310 320 330 340
pF1KB6 RPNL-YYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHA
: :: :: . .::... : : .. : .. .::::::.:... . .. .:: :. :
NP_001 RHNLKYYVLPKKPKKVA-F--DCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAA
860 870 880 890 900 910
350 360 370 380 390 400
pF1KB6 GAYHANLEPEDKTTVHRKW-SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQ
::::.: . :..:: . . ::. ::.:::::::::::::::: :. ::.:.:::
NP_001 LAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQ
920 930 940 950 960 970
410 420 430 440 450
pF1KB6 ESGRAGRDDMKADCILYYGFGDIFRISSMVVMENVGQQK--------LYEMVSYCQNISK
:::::::: . :.:.: . :. :.. ...::. :... :: :: ::.::..
NP_001 ESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITE
980 990 1000 1010 1020 1030
460 470 480 490 500
pF1KB6 CRRVLMAQHFDEV-WNSEACNKM----CDNCCKDSAFERKNITEYCRDLIKILKQAEELN
:::. . .: : .: . :.: :::::: . .. ...:. ....... : . .
NP_001 CRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFV-QEHSSS
1040 1050 1060 1070 1080 1090
510 520 530 540 550
pF1KB6 EKLTPLK------------LIDSWMGKGAAKLRVAGVVAP--TLPREDLEKIIAHFLIQQ
. . .: :.: ..:. .::.. .:. . . :.. :... ......
NP_001 QGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQ-SGIFGKGSAYSRHNAERLFKKLILDK
1100 1110 1120 1130 1140 1150
560 570 580 590 600
pF1KB6 YLKEDYSFTAY-ATISYLKIGPKAN-LLNNEAHAITMQVTKST----QNSFRAESSQTCH
: :: ..: .:.:. .: ::. .::.. .. :.. .:. :... :. ::
NP_001 ILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREE
1160 1170 1180 1190 1200 1210
610 620 630 640
pF1KB6 SEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
NP_001 MVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEK
1220 1230 1240 1250 1260 1270
649 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 13:39:07 2016 done: Sat Nov 5 13:39:08 2016
Total Scan time: 9.390 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]