Result of FASTA (omim) for
pFN21AB7322
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7322, 2352 aa
1>>>pF1KB7322 2352 - 2352 aa - 2352 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.6597+/-0.000575; mu= -26.6452+/- 0.036
mean_var=792.5601+/-163.990, 0's: 0 Z-trim(122.3): 428 B-trim: 0 in 0/61
Lambda= 0.045557
statistics sampled from 39780 (40254) to 39780 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.733), E-opt: 0.2 (0.472), width: 16
Scan time: 20.020
The best scores are: opt bits E(85289)
NP_942592 (OMIM: 615929) ankyrin repeat domain-con (2352) 15375 1028.1 0
XP_005265728 (OMIM: 615929) PREDICTED: ankyrin rep (2351) 15358 1027.0 0
XP_016863501 (OMIM: 615929) PREDICTED: ankyrin rep (2239) 14514 971.5 0
XP_016863502 (OMIM: 615929) PREDICTED: ankyrin rep (2238) 14497 970.4 0
NP_001273700 (OMIM: 615929) ankyrin repeat domain- (2490) 10338 697.1 7.3e-199
NP_115593 (OMIM: 615929) ankyrin repeat domain-con (2603) 10338 697.1 7.6e-199
XP_016863500 (OMIM: 615929) PREDICTED: ankyrin rep (2489) 10333 696.7 9.2e-199
NP_056389 (OMIM: 615929) ankyrin repeat domain-con (2602) 10333 696.7 9.5e-199
XP_016863505 (OMIM: 615929) PREDICTED: ankyrin rep (1229) 7847 533.1 8.3e-150
XP_016863506 (OMIM: 615929) PREDICTED: ankyrin rep (1116) 6986 476.5 8.3e-133
XP_016863503 (OMIM: 615929) PREDICTED: ankyrin rep (1479) 5066 350.4 1e-94
XP_005265730 (OMIM: 615929) PREDICTED: ankyrin rep (1480) 5066 350.4 1e-94
XP_005265729 (OMIM: 615929) PREDICTED: ankyrin rep (1543) 5066 350.4 1e-94
XP_016863504 (OMIM: 615929) PREDICTED: ankyrin rep (1367) 4205 293.8 1e-77
NP_060217 (OMIM: 610500) ankyrin repeat and KH dom (2542) 3796 267.1 2e-69
NP_078944 (OMIM: 610500) ankyrin repeat and KH dom ( 627) 2991 213.7 5.9e-54
NP_001183959 (OMIM: 610500) ankyrin repeat and KH ( 581) 2750 197.8 3.3e-49
NP_060448 (OMIM: 610500) ankyrin repeat and KH dom ( 616) 2600 188.0 3.2e-46
XP_016863601 (OMIM: 106410,600919) PREDICTED: anky (1689) 847 73.1 3.3e-11
XP_016863597 (OMIM: 106410,600919) PREDICTED: anky (1772) 847 73.1 3.4e-11
XP_016863600 (OMIM: 106410,600919) PREDICTED: anky (1755) 842 72.8 4.3e-11
XP_016863599 (OMIM: 106410,600919) PREDICTED: anky (1763) 842 72.8 4.3e-11
XP_016863598 (OMIM: 106410,600919) PREDICTED: anky (1770) 842 72.8 4.3e-11
XP_016863594 (OMIM: 106410,600919) PREDICTED: anky (1810) 842 72.8 4.4e-11
XP_016863592 (OMIM: 106410,600919) PREDICTED: anky (1816) 842 72.8 4.4e-11
XP_016863593 (OMIM: 106410,600919) PREDICTED: anky (1818) 842 72.8 4.4e-11
XP_016863590 (OMIM: 106410,600919) PREDICTED: anky (1839) 842 72.8 4.4e-11
XP_016863588 (OMIM: 106410,600919) PREDICTED: anky (1850) 842 72.8 4.4e-11
XP_016863587 (OMIM: 106410,600919) PREDICTED: anky (1851) 842 72.8 4.4e-11
XP_016863585 (OMIM: 106410,600919) PREDICTED: anky (1862) 842 72.8 4.5e-11
NP_001120965 (OMIM: 106410,600919) ankyrin-2 isofo (1863) 842 72.8 4.5e-11
XP_016863583 (OMIM: 106410,600919) PREDICTED: anky (1871) 842 72.8 4.5e-11
XP_016863584 (OMIM: 106410,600919) PREDICTED: anky (1871) 842 72.8 4.5e-11
NP_066187 (OMIM: 106410,600919) ankyrin-2 isoform (1872) 842 72.8 4.5e-11
XP_016863582 (OMIM: 106410,600919) PREDICTED: anky (1881) 842 72.8 4.5e-11
XP_016863581 (OMIM: 106410,600919) PREDICTED: anky (1882) 842 72.8 4.5e-11
XP_016863579 (OMIM: 106410,600919) PREDICTED: anky (1886) 842 72.8 4.5e-11
XP_016863578 (OMIM: 106410,600919) PREDICTED: anky (1887) 842 72.8 4.5e-11
XP_016863577 (OMIM: 106410,600919) PREDICTED: anky (1893) 842 72.8 4.5e-11
XP_016863576 (OMIM: 106410,600919) PREDICTED: anky (1898) 842 72.8 4.5e-11
XP_016863575 (OMIM: 106410,600919) PREDICTED: anky (1899) 842 72.8 4.5e-11
XP_016863574 (OMIM: 106410,600919) PREDICTED: anky (1902) 842 72.8 4.5e-11
XP_016863573 (OMIM: 106410,600919) PREDICTED: anky (1915) 842 72.8 4.6e-11
XP_016863572 (OMIM: 106410,600919) PREDICTED: anky (1917) 842 72.8 4.6e-11
XP_016863571 (OMIM: 106410,600919) PREDICTED: anky (1926) 842 72.8 4.6e-11
XP_016863570 (OMIM: 106410,600919) PREDICTED: anky (1931) 842 72.8 4.6e-11
XP_016863569 (OMIM: 106410,600919) PREDICTED: anky (1970) 842 72.8 4.7e-11
XP_016863568 (OMIM: 106410,600919) PREDICTED: anky (2006) 842 72.9 4.7e-11
XP_016863567 (OMIM: 106410,600919) PREDICTED: anky (2020) 842 72.9 4.7e-11
XP_016863596 (OMIM: 106410,600919) PREDICTED: anky (1797) 839 72.6 5e-11
>>NP_942592 (OMIM: 615929) ankyrin repeat domain-contain (2352 aa)
initn: 15375 init1: 15375 opt: 15375 Z-score: 5480.7 bits: 1028.1 E(85289): 0
Smith-Waterman score: 15375; 100.0% identity (100.0% similar) in 2352 aa overlap (1-2352:1-2352)
10 20 30 40 50 60
pF1KB7 MEKATVPVAAATAAEGEGSPPAVAAVAGPPAAAEVGGGVGGSSRARSASSPRGMVRVCDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MEKATVPVAAATAAEGEGSPPAVAAVAGPPAAAEVGGGVGGSSRARSASSPRGMVRVCDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 LLKKKPPQQQHHKAKRNRTCRPPSSSESSSDSDNSGGGGGGGGGGGGGGGTSSNNSEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 LLKKKPPQQQHHKAKRNRTCRPPSSSESSSDSDNSGGGGGGGGGGGGGGGTSSNNSEEEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 DDDDEEEEVSEVESFILDQDDLENPMLETASKLLLSGTADGADLRTVDPETQARLEALLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 DDDDEEEEVSEVESFILDQDDLENPMLETASKLLLSGTADGADLRTVDPETQARLEALLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 AAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 AAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 DITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 DITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 EDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 LEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 LEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 ELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 ELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 ACCGGFLEVADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 ACCGGFLEVADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 LTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 LTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 ANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 ANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 NNLLSAPPPDVTQLTPPSHDLNRAPRVPVQALPMVVPPQEPDKPPANVATTLPIRNKAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 NNLLSAPPPDVTQLTPPSHDLNRAPRVPVQALPMVVPPQEPDKPPANVATTLPIRNKAVS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 GRASAMSNTPTHSIAASISQPQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTLAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 GRASAMSNTPTHSIAASISQPQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTLAC
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 AGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 AGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 TPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 TPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 RTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 RTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB7 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB7 HYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 HYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLM
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB7 AAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 AAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQAAE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB7 ANKNASILLEELDLEKLREESRRLALAAKREKRKEKRRKKKEEQRRKLEEIEAKNKENFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 ANKNASILLEELDLEKLREESRRLALAAKREKRKEKRRKKKEEQRRKLEEIEAKNKENFE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB7 LQAAQEKEKLKVEDEPEVLTEPPSATTTTTIGISATWTTLAGSHGKRNNTITTTSSKRKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 LQAAQEKEKLKVEDEPEVLTEPPSATTTTTIGISATWTTLAGSHGKRNNTITTTSSKRKN
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB7 RKNKITPENVQIIFDDPLPISYSQPEKVNGESKSSSTSESGDSDNMRISSCSDESSNSNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 RKNKITPENVQIIFDDPLPISYSQPEKVNGESKSSSTSESGDSDNMRISSCSDESSNSNS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB7 SRKSDNHSPAVVTTTVSSKKQPSVLVTFPKEERKSVSGKASIKLSETISEGTSNSLSTCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 SRKSDNHSPAVVTTTVSSKKQPSVLVTFPKEERKSVSGKASIKLSETISEGTSNSLSTCT
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB7 KSGPSPLSSPNGKLTVASPKRGQKREEGWKEVVRRSKKVSVPSTVISRVIGRGGCNINAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 KSGPSPLSSPNGKLTVASPKRGQKREEGWKEVVRRSKKVSVPSTVISRVIGRGGCNINAI
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB7 REFTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALIKDPDKEIDELIPKNRLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 REFTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALIKDPDKEIDELIPKNRLKS
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB7 SSANSKIGSSAPTTTAANTSLMGIKMTTVALSSTSQTATALTVPAISSASTHKTIKNPVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 SSANSKIGSSAPTTTAANTSLMGIKMTTVALSSTSQTATALTVPAISSASTHKTIKNPVN
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB7 NVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQSTWGPFPVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 NVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQSTWGPFPVRP
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB7 LSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGTSTNGSPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 LSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGTSTNGSPSS
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB7 PSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMPTAKEHYPVSSPSSPSPPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 PSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMPTAKEHYPVSSPSSPSPPAQ
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB7 PGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTNTRPPNSSSSSGSSSAHSNQQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 PGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTNTRPPNSSSSSGSSSAHSNQQQP
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KB7 PGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYPMPQTPMGCPQPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 PGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYPMPQTPMGCPQPTP
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KB7 KMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNHIKRPHSVPSSVQLPSTLSTQSACQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 KMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNHIKRPHSVPSSVQLPSTLSTQSACQ
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KB7 NSVHPANKPIAPNFSAPLPFGPFSTLFENSPTSAHAFWGGSVVSSQSTPESMLSGKSSYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 NSVHPANKPIAPNFSAPLPFGPFSTLFENSPTSAHAFWGGSVVSSQSTPESMLSGKSSYL
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KB7 PNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDSPYGSVTPSSTHLGNFASNISGGQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 PNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDSPYGSVTPSSTHLGNFASNISGGQM
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KB7 YGPGAPLGGAPAAANFNRQHFSPLSLLTPCSSASNDSSAQSVSSGVRAPSPAPSSVPLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 YGPGAPLGGAPAAANFNRQHFSPLSLLTPCSSASNDSSAQSVSSGVRAPSPAPSSVPLGS
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KB7 EKPSNVSQDRKVPVPIGTERSARIRQTGTSAPSVIGSNLSTSVGHSGIWSFEGIGGNQDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 EKPSNVSQDRKVPVPIGTERSARIRQTGTSAPSVIGSNLSTSVGHSGIWSFEGIGGNQDK
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KB7 VDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGIVTPSGTFHQHVPAGYMDFPKVGGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 VDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGIVTPSGTFHQHVPAGYMDFPKVGGM
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KB7 PFSVYGNAMIPPVAPIPDGAGGPIFNGPHAADPSWNSLIKMVSSSTENNGPQTVWTGPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 PFSVYGNAMIPPVAPIPDGAGGPIFNGPHAADPSWNSLIKMVSSSTENNGPQTVWTGPWA
2290 2300 2310 2320 2330 2340
2350
pF1KB7 PHMNSVHMNQLG
::::::::::::
NP_942 PHMNSVHMNQLG
2350
>>XP_005265728 (OMIM: 615929) PREDICTED: ankyrin repeat (2351 aa)
initn: 10334 init1: 10334 opt: 15358 Z-score: 5474.7 bits: 1027.0 E(85289): 0
Smith-Waterman score: 15358; 100.0% identity (100.0% similar) in 2352 aa overlap (1-2352:1-2351)
10 20 30 40 50 60
pF1KB7 MEKATVPVAAATAAEGEGSPPAVAAVAGPPAAAEVGGGVGGSSRARSASSPRGMVRVCDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEKATVPVAAATAAEGEGSPPAVAAVAGPPAAAEVGGGVGGSSRARSASSPRGMVRVCDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 LLKKKPPQQQHHKAKRNRTCRPPSSSESSSDSDNSGGGGGGGGGGGGGGGTSSNNSEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLKKKPPQQQHHKAKRNRTCRPPSSSESSSDSDNSGGGGGGGGGGGGGGGTSSNNSEEEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 DDDDEEEEVSEVESFILDQDDLENPMLETASKLLLSGTADGADLRTVDPETQARLEALLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDDDEEEEVSEVESFILDQDDLENPMLETASKLLLSGTADGADLRTVDPETQARLEALLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 AAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 DITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 LEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 ELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 ACCGGFLEVADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ACCGGFLEVADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 LTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 ANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 NNLLSAPPPDVTQLTPPSHDLNRAPRVPVQALPMVVPPQEPDKPPANVATTLPIRNKAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_005 NNLLSAPPPDVTQLTPPSHDLNRAPRVPVQALPMVVPPQEPDKPPANVATTLPIRNK-VS
730 740 750 760 770
790 800 810 820 830 840
pF1KB7 GRASAMSNTPTHSIAASISQPQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTLAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRASAMSNTPTHSIAASISQPQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTLAC
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB7 AGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKD
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB7 TPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINS
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB7 RTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLL
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB7 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKG
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KB7 HYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLM
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KB7 AAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQAAE
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KB7 ANKNASILLEELDLEKLREESRRLALAAKREKRKEKRRKKKEEQRRKLEEIEAKNKENFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ANKNASILLEELDLEKLREESRRLALAAKREKRKEKRRKKKEEQRRKLEEIEAKNKENFE
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KB7 LQAAQEKEKLKVEDEPEVLTEPPSATTTTTIGISATWTTLAGSHGKRNNTITTTSSKRKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQAAQEKEKLKVEDEPEVLTEPPSATTTTTIGISATWTTLAGSHGKRNNTITTTSSKRKN
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KB7 RKNKITPENVQIIFDDPLPISYSQPEKVNGESKSSSTSESGDSDNMRISSCSDESSNSNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKNKITPENVQIIFDDPLPISYSQPEKVNGESKSSSTSESGDSDNMRISSCSDESSNSNS
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KB7 SRKSDNHSPAVVTTTVSSKKQPSVLVTFPKEERKSVSGKASIKLSETISEGTSNSLSTCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRKSDNHSPAVVTTTVSSKKQPSVLVTFPKEERKSVSGKASIKLSETISEGTSNSLSTCT
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KB7 KSGPSPLSSPNGKLTVASPKRGQKREEGWKEVVRRSKKVSVPSTVISRVIGRGGCNINAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSGPSPLSSPNGKLTVASPKRGQKREEGWKEVVRRSKKVSVPSTVISRVIGRGGCNINAI
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KB7 REFTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALIKDPDKEIDELIPKNRLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REFTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALIKDPDKEIDELIPKNRLKS
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KB7 SSANSKIGSSAPTTTAANTSLMGIKMTTVALSSTSQTATALTVPAISSASTHKTIKNPVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSANSKIGSSAPTTTAANTSLMGIKMTTVALSSTSQTATALTVPAISSASTHKTIKNPVN
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670 1680
pF1KB7 NVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQSTWGPFPVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQSTWGPFPVRP
1620 1630 1640 1650 1660 1670
1690 1700 1710 1720 1730 1740
pF1KB7 LSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGTSTNGSPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGTSTNGSPSS
1680 1690 1700 1710 1720 1730
1750 1760 1770 1780 1790 1800
pF1KB7 PSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMPTAKEHYPVSSPSSPSPPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMPTAKEHYPVSSPSSPSPPAQ
1740 1750 1760 1770 1780 1790
1810 1820 1830 1840 1850 1860
pF1KB7 PGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTNTRPPNSSSSSGSSSAHSNQQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTNTRPPNSSSSSGSSSAHSNQQQP
1800 1810 1820 1830 1840 1850
1870 1880 1890 1900 1910 1920
pF1KB7 PGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYPMPQTPMGCPQPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYPMPQTPMGCPQPTP
1860 1870 1880 1890 1900 1910
1930 1940 1950 1960 1970 1980
pF1KB7 KMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNHIKRPHSVPSSVQLPSTLSTQSACQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNHIKRPHSVPSSVQLPSTLSTQSACQ
1920 1930 1940 1950 1960 1970
1990 2000 2010 2020 2030 2040
pF1KB7 NSVHPANKPIAPNFSAPLPFGPFSTLFENSPTSAHAFWGGSVVSSQSTPESMLSGKSSYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSVHPANKPIAPNFSAPLPFGPFSTLFENSPTSAHAFWGGSVVSSQSTPESMLSGKSSYL
1980 1990 2000 2010 2020 2030
2050 2060 2070 2080 2090 2100
pF1KB7 PNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDSPYGSVTPSSTHLGNFASNISGGQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDSPYGSVTPSSTHLGNFASNISGGQM
2040 2050 2060 2070 2080 2090
2110 2120 2130 2140 2150 2160
pF1KB7 YGPGAPLGGAPAAANFNRQHFSPLSLLTPCSSASNDSSAQSVSSGVRAPSPAPSSVPLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YGPGAPLGGAPAAANFNRQHFSPLSLLTPCSSASNDSSAQSVSSGVRAPSPAPSSVPLGS
2100 2110 2120 2130 2140 2150
2170 2180 2190 2200 2210 2220
pF1KB7 EKPSNVSQDRKVPVPIGTERSARIRQTGTSAPSVIGSNLSTSVGHSGIWSFEGIGGNQDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKPSNVSQDRKVPVPIGTERSARIRQTGTSAPSVIGSNLSTSVGHSGIWSFEGIGGNQDK
2160 2170 2180 2190 2200 2210
2230 2240 2250 2260 2270 2280
pF1KB7 VDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGIVTPSGTFHQHVPAGYMDFPKVGGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGIVTPSGTFHQHVPAGYMDFPKVGGM
2220 2230 2240 2250 2260 2270
2290 2300 2310 2320 2330 2340
pF1KB7 PFSVYGNAMIPPVAPIPDGAGGPIFNGPHAADPSWNSLIKMVSSSTENNGPQTVWTGPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PFSVYGNAMIPPVAPIPDGAGGPIFNGPHAADPSWNSLIKMVSSSTENNGPQTVWTGPWA
2280 2290 2300 2310 2320 2330
2350
pF1KB7 PHMNSVHMNQLG
::::::::::::
XP_005 PHMNSVHMNQLG
2340 2350
>>XP_016863501 (OMIM: 615929) PREDICTED: ankyrin repeat (2239 aa)
initn: 14514 init1: 14514 opt: 14514 Z-score: 5175.2 bits: 971.5 E(85289): 0
Smith-Waterman score: 14514; 99.9% identity (100.0% similar) in 2226 aa overlap (127-2352:14-2239)
100 110 120 130 140 150
pF1KB7 GGGGGGGGGGGGGGTSSNNSEEEEDDDDEEEEVSEVESFILDQDDLENPMLETASKLLLS
:.. ::::::::::::::::::::::::::
XP_016 MVETAAEMEAYVLEDILEVESFILDQDDLENPMLETASKLLLS
10 20 30 40
160 170 180 190 200 210
pF1KB7 GTADGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTADGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAA
50 60 70 80 90 100
220 230 240 250 260 270
pF1KB7 AALTRMRAESTANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AALTRMRAESTANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACS
110 120 130 140 150 160
280 290 300 310 320 330
pF1KB7 AGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNT
170 180 190 200 210 220
340 350 360 370 380 390
pF1KB7 ALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTH
230 240 250 260 270 280
400 410 420 430 440 450
pF1KB7 SNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDS
290 300 310 320 330 340
460 470 480 490 500 510
pF1KB7 GAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMV
350 360 370 380 390 400
520 530 540 550 560 570
pF1KB7 ALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADIELGCSTPLMEAAQEGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADIELGCSTPLMEAAQEGH
410 420 430 440 450 460
580 590 600 610 620 630
pF1KB7 LELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMK
470 480 490 500 510 520
640 650 660 670 680 690
pF1KB7 AARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKD
530 540 550 560 570 580
700 710 720 730 740 750
pF1KB7 GSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPPPDVTQLTPPSHDLNRAPRVPVQALPMVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPPPDVTQLTPPSHDLNRAPRVPVQALPMVV
590 600 610 620 630 640
760 770 780 790 800 810
pF1KB7 PPQEPDKPPANVATTLPIRNKAVSGRASAMSNTPTHSIAASISQPQTPTPSPIISPSAML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPQEPDKPPANVATTLPIRNKAVSGRASAMSNTPTHSIAASISQPQTPTPSPIISPSAML
650 660 670 680 690 700
820 830 840 850 860 870
pF1KB7 PIYPAIDIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIYPAIDIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAG
710 720 730 740 750 760
880 890 900 910 920 930
pF1KB7 HVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPL
770 780 790 800 810 820
940 950 960 970 980 990
pF1KB7 SLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQ
830 840 850 860 870 880
1000 1010 1020 1030 1040 1050
pF1KB7 IETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDK
890 900 910 920 930 940
1060 1070 1080 1090 1100 1110
pF1KB7 GADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLD
950 960 970 980 990 1000
1120 1130 1140 1150 1160 1170
pF1KB7 VVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITD
1010 1020 1030 1040 1050 1060
1180 1190 1200 1210 1220 1230
pF1KB7 KEMLKKCHLCMESIVQAKDRQAAEANKNASILLEELDLEKLREESRRLALAAKREKRKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEMLKKCHLCMESIVQAKDRQAAEANKNASILLEELDLEKLREESRRLALAAKREKRKEK
1070 1080 1090 1100 1110 1120
1240 1250 1260 1270 1280 1290
pF1KB7 RRKKKEEQRRKLEEIEAKNKENFELQAAQEKEKLKVEDEPEVLTEPPSATTTTTIGISAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRKKKEEQRRKLEEIEAKNKENFELQAAQEKEKLKVEDEPEVLTEPPSATTTTTIGISAT
1130 1140 1150 1160 1170 1180
1300 1310 1320 1330 1340 1350
pF1KB7 WTTLAGSHGKRNNTITTTSSKRKNRKNKITPENVQIIFDDPLPISYSQPEKVNGESKSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WTTLAGSHGKRNNTITTTSSKRKNRKNKITPENVQIIFDDPLPISYSQPEKVNGESKSSS
1190 1200 1210 1220 1230 1240
1360 1370 1380 1390 1400 1410
pF1KB7 TSESGDSDNMRISSCSDESSNSNSSRKSDNHSPAVVTTTVSSKKQPSVLVTFPKEERKSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSESGDSDNMRISSCSDESSNSNSSRKSDNHSPAVVTTTVSSKKQPSVLVTFPKEERKSV
1250 1260 1270 1280 1290 1300
1420 1430 1440 1450 1460 1470
pF1KB7 SGKASIKLSETISEGTSNSLSTCTKSGPSPLSSPNGKLTVASPKRGQKREEGWKEVVRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGKASIKLSETISEGTSNSLSTCTKSGPSPLSSPNGKLTVASPKRGQKREEGWKEVVRRS
1310 1320 1330 1340 1350 1360
1480 1490 1500 1510 1520 1530
pF1KB7 KKVSVPSTVISRVIGRGGCNINAIREFTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKVSVPSTVISRVIGRGGCNINAIREFTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQ
1370 1380 1390 1400 1410 1420
1540 1550 1560 1570 1580 1590
pF1KB7 LINALIKDPDKEIDELIPKNRLKSSSANSKIGSSAPTTTAANTSLMGIKMTTVALSSTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LINALIKDPDKEIDELIPKNRLKSSSANSKIGSSAPTTTAANTSLMGIKMTTVALSSTSQ
1430 1440 1450 1460 1470 1480
1600 1610 1620 1630 1640 1650
pF1KB7 TATALTVPAISSASTHKTIKNPVNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TATALTVPAISSASTHKTIKNPVNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPR
1490 1500 1510 1520 1530 1540
1660 1670 1680 1690 1700 1710
pF1KB7 LPMTHFGGTFPPAQSTWGPFPVRPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPMTHFGGTFPPAQSTWGPFPVRPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTS
1550 1560 1570 1580 1590 1600
1720 1730 1740 1750 1760 1770
pF1KB7 SPTTTTSSSASTVPGTSTNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPTTTTSSSASTVPGTSTNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNA
1610 1620 1630 1640 1650 1660
1780 1790 1800 1810 1820 1830
pF1KB7 TYPMPTAKEHYPVSSPSSPSPPAQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYPMPTAKEHYPVSSPSSPSPPAQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVET
1670 1680 1690 1700 1710 1720
1840 1850 1860 1870 1880 1890
pF1KB7 TNTRPPNSSSSSGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNTRPPNSSSSSGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPV
1730 1740 1750 1760 1770 1780
1900 1910 1920 1930 1940 1950
pF1KB7 AVPSTAPVTYPMPQTPMGCPQPTPKMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVPSTAPVTYPMPQTPMGCPQPTPKMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNH
1790 1800 1810 1820 1830 1840
1960 1970 1980 1990 2000 2010
pF1KB7 IKRPHSVPSSVQLPSTLSTQSACQNSVHPANKPIAPNFSAPLPFGPFSTLFENSPTSAHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKRPHSVPSSVQLPSTLSTQSACQNSVHPANKPIAPNFSAPLPFGPFSTLFENSPTSAHA
1850 1860 1870 1880 1890 1900
2020 2030 2040 2050 2060 2070
pF1KB7 FWGGSVVSSQSTPESMLSGKSSYLPNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FWGGSVVSSQSTPESMLSGKSSYLPNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDS
1910 1920 1930 1940 1950 1960
2080 2090 2100 2110 2120 2130
pF1KB7 PYGSVTPSSTHLGNFASNISGGQMYGPGAPLGGAPAAANFNRQHFSPLSLLTPCSSASND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYGSVTPSSTHLGNFASNISGGQMYGPGAPLGGAPAAANFNRQHFSPLSLLTPCSSASND
1970 1980 1990 2000 2010 2020
2140 2150 2160 2170 2180 2190
pF1KB7 SSAQSVSSGVRAPSPAPSSVPLGSEKPSNVSQDRKVPVPIGTERSARIRQTGTSAPSVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSAQSVSSGVRAPSPAPSSVPLGSEKPSNVSQDRKVPVPIGTERSARIRQTGTSAPSVIG
2030 2040 2050 2060 2070 2080
2200 2210 2220 2230 2240 2250
pF1KB7 SNLSTSVGHSGIWSFEGIGGNQDKVDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNLSTSVGHSGIWSFEGIGGNQDKVDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGI
2090 2100 2110 2120 2130 2140
2260 2270 2280 2290 2300 2310
pF1KB7 VTPSGTFHQHVPAGYMDFPKVGGMPFSVYGNAMIPPVAPIPDGAGGPIFNGPHAADPSWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTPSGTFHQHVPAGYMDFPKVGGMPFSVYGNAMIPPVAPIPDGAGGPIFNGPHAADPSWN
2150 2160 2170 2180 2190 2200
2320 2330 2340 2350
pF1KB7 SLIKMVSSSTENNGPQTVWTGPWAPHMNSVHMNQLG
::::::::::::::::::::::::::::::::::::
XP_016 SLIKMVSSSTENNGPQTVWTGPWAPHMNSVHMNQLG
2210 2220 2230
>>XP_016863502 (OMIM: 615929) PREDICTED: ankyrin repeat (2238 aa)
initn: 14495 init1: 10328 opt: 14497 Z-score: 5169.1 bits: 970.4 E(85289): 0
Smith-Waterman score: 14497; 99.8% identity (99.9% similar) in 2226 aa overlap (127-2352:14-2238)
100 110 120 130 140 150
pF1KB7 GGGGGGGGGGGGGGTSSNNSEEEEDDDDEEEEVSEVESFILDQDDLENPMLETASKLLLS
:.. ::::::::::::::::::::::::::
XP_016 MVETAAEMEAYVLEDILEVESFILDQDDLENPMLETASKLLLS
10 20 30 40
160 170 180 190 200 210
pF1KB7 GTADGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTADGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAA
50 60 70 80 90 100
220 230 240 250 260 270
pF1KB7 AALTRMRAESTANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AALTRMRAESTANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACS
110 120 130 140 150 160
280 290 300 310 320 330
pF1KB7 AGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNT
170 180 190 200 210 220
340 350 360 370 380 390
pF1KB7 ALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTH
230 240 250 260 270 280
400 410 420 430 440 450
pF1KB7 SNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDS
290 300 310 320 330 340
460 470 480 490 500 510
pF1KB7 GAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMV
350 360 370 380 390 400
520 530 540 550 560 570
pF1KB7 ALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADIELGCSTPLMEAAQEGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADIELGCSTPLMEAAQEGH
410 420 430 440 450 460
580 590 600 610 620 630
pF1KB7 LELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMK
470 480 490 500 510 520
640 650 660 670 680 690
pF1KB7 AARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKD
530 540 550 560 570 580
700 710 720 730 740 750
pF1KB7 GSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPPPDVTQLTPPSHDLNRAPRVPVQALPMVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPPPDVTQLTPPSHDLNRAPRVPVQALPMVV
590 600 610 620 630 640
760 770 780 790 800 810
pF1KB7 PPQEPDKPPANVATTLPIRNKAVSGRASAMSNTPTHSIAASISQPQTPTPSPIISPSAML
::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_016 PPQEPDKPPANVATTLPIRNK-VSGRASAMSNTPTHSIAASISQPQTPTPSPIISPSAML
650 660 670 680 690 700
820 830 840 850 860 870
pF1KB7 PIYPAIDIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIYPAIDIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAG
710 720 730 740 750 760
880 890 900 910 920 930
pF1KB7 HVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPL
770 780 790 800 810 820
940 950 960 970 980 990
pF1KB7 SLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQ
830 840 850 860 870 880
1000 1010 1020 1030 1040 1050
pF1KB7 IETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDK
890 900 910 920 930 940
1060 1070 1080 1090 1100 1110
pF1KB7 GADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLD
950 960 970 980 990 1000
1120 1130 1140 1150 1160 1170
pF1KB7 VVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITD
1010 1020 1030 1040 1050 1060
1180 1190 1200 1210 1220 1230
pF1KB7 KEMLKKCHLCMESIVQAKDRQAAEANKNASILLEELDLEKLREESRRLALAAKREKRKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEMLKKCHLCMESIVQAKDRQAAEANKNASILLEELDLEKLREESRRLALAAKREKRKEK
1070 1080 1090 1100 1110 1120
1240 1250 1260 1270 1280 1290
pF1KB7 RRKKKEEQRRKLEEIEAKNKENFELQAAQEKEKLKVEDEPEVLTEPPSATTTTTIGISAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRKKKEEQRRKLEEIEAKNKENFELQAAQEKEKLKVEDEPEVLTEPPSATTTTTIGISAT
1130 1140 1150 1160 1170 1180
1300 1310 1320 1330 1340 1350
pF1KB7 WTTLAGSHGKRNNTITTTSSKRKNRKNKITPENVQIIFDDPLPISYSQPEKVNGESKSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WTTLAGSHGKRNNTITTTSSKRKNRKNKITPENVQIIFDDPLPISYSQPEKVNGESKSSS
1190 1200 1210 1220 1230 1240
1360 1370 1380 1390 1400 1410
pF1KB7 TSESGDSDNMRISSCSDESSNSNSSRKSDNHSPAVVTTTVSSKKQPSVLVTFPKEERKSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSESGDSDNMRISSCSDESSNSNSSRKSDNHSPAVVTTTVSSKKQPSVLVTFPKEERKSV
1250 1260 1270 1280 1290 1300
1420 1430 1440 1450 1460 1470
pF1KB7 SGKASIKLSETISEGTSNSLSTCTKSGPSPLSSPNGKLTVASPKRGQKREEGWKEVVRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGKASIKLSETISEGTSNSLSTCTKSGPSPLSSPNGKLTVASPKRGQKREEGWKEVVRRS
1310 1320 1330 1340 1350 1360
1480 1490 1500 1510 1520 1530
pF1KB7 KKVSVPSTVISRVIGRGGCNINAIREFTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKVSVPSTVISRVIGRGGCNINAIREFTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQ
1370 1380 1390 1400 1410 1420
1540 1550 1560 1570 1580 1590
pF1KB7 LINALIKDPDKEIDELIPKNRLKSSSANSKIGSSAPTTTAANTSLMGIKMTTVALSSTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LINALIKDPDKEIDELIPKNRLKSSSANSKIGSSAPTTTAANTSLMGIKMTTVALSSTSQ
1430 1440 1450 1460 1470 1480
1600 1610 1620 1630 1640 1650
pF1KB7 TATALTVPAISSASTHKTIKNPVNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TATALTVPAISSASTHKTIKNPVNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPR
1490 1500 1510 1520 1530 1540
1660 1670 1680 1690 1700 1710
pF1KB7 LPMTHFGGTFPPAQSTWGPFPVRPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPMTHFGGTFPPAQSTWGPFPVRPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTS
1550 1560 1570 1580 1590 1600
1720 1730 1740 1750 1760 1770
pF1KB7 SPTTTTSSSASTVPGTSTNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPTTTTSSSASTVPGTSTNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNA
1610 1620 1630 1640 1650 1660
1780 1790 1800 1810 1820 1830
pF1KB7 TYPMPTAKEHYPVSSPSSPSPPAQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYPMPTAKEHYPVSSPSSPSPPAQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVET
1670 1680 1690 1700 1710 1720
1840 1850 1860 1870 1880 1890
pF1KB7 TNTRPPNSSSSSGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNTRPPNSSSSSGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPV
1730 1740 1750 1760 1770 1780
1900 1910 1920 1930 1940 1950
pF1KB7 AVPSTAPVTYPMPQTPMGCPQPTPKMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVPSTAPVTYPMPQTPMGCPQPTPKMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNH
1790 1800 1810 1820 1830 1840
1960 1970 1980 1990 2000 2010
pF1KB7 IKRPHSVPSSVQLPSTLSTQSACQNSVHPANKPIAPNFSAPLPFGPFSTLFENSPTSAHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKRPHSVPSSVQLPSTLSTQSACQNSVHPANKPIAPNFSAPLPFGPFSTLFENSPTSAHA
1850 1860 1870 1880 1890 1900
2020 2030 2040 2050 2060 2070
pF1KB7 FWGGSVVSSQSTPESMLSGKSSYLPNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FWGGSVVSSQSTPESMLSGKSSYLPNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDS
1910 1920 1930 1940 1950 1960
2080 2090 2100 2110 2120 2130
pF1KB7 PYGSVTPSSTHLGNFASNISGGQMYGPGAPLGGAPAAANFNRQHFSPLSLLTPCSSASND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYGSVTPSSTHLGNFASNISGGQMYGPGAPLGGAPAAANFNRQHFSPLSLLTPCSSASND
1970 1980 1990 2000 2010 2020
2140 2150 2160 2170 2180 2190
pF1KB7 SSAQSVSSGVRAPSPAPSSVPLGSEKPSNVSQDRKVPVPIGTERSARIRQTGTSAPSVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSAQSVSSGVRAPSPAPSSVPLGSEKPSNVSQDRKVPVPIGTERSARIRQTGTSAPSVIG
2030 2040 2050 2060 2070 2080
2200 2210 2220 2230 2240 2250
pF1KB7 SNLSTSVGHSGIWSFEGIGGNQDKVDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNLSTSVGHSGIWSFEGIGGNQDKVDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGI
2090 2100 2110 2120 2130 2140
2260 2270 2280 2290 2300 2310
pF1KB7 VTPSGTFHQHVPAGYMDFPKVGGMPFSVYGNAMIPPVAPIPDGAGGPIFNGPHAADPSWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTPSGTFHQHVPAGYMDFPKVGGMPFSVYGNAMIPPVAPIPDGAGGPIFNGPHAADPSWN
2150 2160 2170 2180 2190 2200
2320 2330 2340 2350
pF1KB7 SLIKMVSSSTENNGPQTVWTGPWAPHMNSVHMNQLG
::::::::::::::::::::::::::::::::::::
XP_016 SLIKMVSSSTENNGPQTVWTGPWAPHMNSVHMNQLG
2210 2220 2230
>>NP_001273700 (OMIM: 615929) ankyrin repeat domain-cont (2490 aa)
initn: 10333 init1: 10333 opt: 10338 Z-score: 3691.2 bits: 697.1 E(85289): 7.3e-199
Smith-Waterman score: 13449; 89.5% identity (89.5% similar) in 2384 aa overlap (220-2352:107-2490)
190 200 210 220 230 240
pF1KB7 ADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAEACSEGDVNA
::::::::::::::::::::::::::::::
NP_001 ADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAEACSEGDVNA
80 90 100 110 120 130
250 260 270 280 290 300
pF1KB7 VRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAA
140 150 160 170 180 190
310 320 330 340 350 360
pF1KB7 NGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHT
200 210 220 230 240 250
370 380 390 400 410 420
pF1KB7 PLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEH
260 270 280 290 300 310
430 440 450 460 470 480
pF1KB7 KTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIER
320 330 340 350 360 370
490 500 510 520 530 540
pF1KB7 GASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEV
380 390 400 410 420 430
550 560 570 580 590 600
pF1KB7 ADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGH
440 450 460 470 480 490
610 620 630 640 650 660
pF1KB7 TDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLS
500 510 520 530 540 550
670 680 690 700 710 720
pF1KB7 LACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPPP
560 570 580 590 600 610
730 740 750 760 770
pF1KB7 DVTQLTPPSHDLNRAPRVPVQALPMVVPPQEPDKPPANVATTLPIRNKA-----------
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVTQLTPPSHDLNRAPRVPVQALPMVVPPQEPDKPPANVATTLPIRNKAASKQKSSSHLP
620 630 640 650 660 670
pF1KB7 ------------------------------------------------------------
NP_001 ANSQDVQGYITNQSPESIVEEAQGKLTELEQRIKEAIEKNAQLQSLELAHADQLTKEKIE
680 690 700 710 720 730
pF1KB7 ------------------------------------------------------------
NP_001 ELNKTREEQIQKKQKILEELQKVERELQLKTQQQLKKQYLEVKAQRIQLQQQQQQSCQHL
740 750 760 770 780 790
pF1KB7 ------------------------------------------------------------
NP_001 GLLTPVGVGEQLSEGDYARLQQVDPVLLKDEPQQTAAQMGFAPIQPLAMPQALPLAAGPL
800 810 820 830 840 850
pF1KB7 ------------------------------------------------------------
NP_001 PPGSIANLTELQGVIVGQPVLGQAQLAGLGQGILTETQQGLMVASPAQTLNDTLDDIMAA
860 870 880 890 900 910
780 790 800 810 820 830
pF1KB7 VSGRASAMSNTPTHSIAASISQPQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSGRASAMSNTPTHSIAASISQPQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTL
920 930 940 950 960 970
840 850 860 870 880 890
pF1KB7 ACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERT
980 990 1000 1010 1020 1030
900 910 920 930 940 950
pF1KB7 KDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEI
1040 1050 1060 1070 1080 1090
960 970 980 990 1000 1010
pF1KB7 NSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVS
1100 1110 1120 1130 1140 1150
1020 1030 1040 1050 1060 1070
pF1KB7 LLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAAD
1160 1170 1180 1190 1200 1210
1080 1090 1100 1110 1120 1130
pF1KB7 KGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITP
1220 1230 1240 1250 1260 1270
1140 1150 1160 1170 1180 1190
pF1KB7 LMAAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMAAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQA
1280 1290 1300 1310 1320 1330
1200 1210 1220 1230 1240 1250
pF1KB7 AEANKNASILLEELDLEKLREESRRLALAAKREKRKEKRRKKKEEQRRKLEEIEAKNKEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEANKNASILLEELDLEKLREESRRLALAAKREKRKEKRRKKKEEQRRKLEEIEAKNKEN
1340 1350 1360 1370 1380 1390
1260 1270 1280 1290 1300 1310
pF1KB7 FELQAAQEKEKLKVEDEPEVLTEPPSATTTTTIGISATWTTLAGSHGKRNNTITTTSSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FELQAAQEKEKLKVEDEPEVLTEPPSATTTTTIGISATWTTLAGSHGKRNNTITTTSSKR
1400 1410 1420 1430 1440 1450
1320 1330 1340 1350 1360 1370
pF1KB7 KNRKNKITPENVQIIFDDPLPISYSQPEKVNGESKSSSTSESGDSDNMRISSCSDESSNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNRKNKITPENVQIIFDDPLPISYSQPEKVNGESKSSSTSESGDSDNMRISSCSDESSNS
1460 1470 1480 1490 1500 1510
1380 1390 1400 1410 1420 1430
pF1KB7 NSSRKSDNHSPAVVTTTVSSKKQPSVLVTFPKEERKSVSGKASIKLSETISEGTSNSLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSSRKSDNHSPAVVTTTVSSKKQPSVLVTFPKEERKSVSGKASIKLSETISEGTSNSLST
1520 1530 1540 1550 1560 1570
1440 1450 1460 1470 1480 1490
pF1KB7 CTKSGPSPLSSPNGKLTVASPKRGQKREEGWKEVVRRSKKVSVPSTVISRVIGRGGCNIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTKSGPSPLSSPNGKLTVASPKRGQKREEGWKEVVRRSKKVSVPSTVISRVIGRGGCNIN
1580 1590 1600 1610 1620 1630
1500 1510 1520 1530 1540 1550
pF1KB7 AIREFTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALIKDPDKEIDELIPKNRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIREFTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALIKDPDKEIDELIPKNRL
1640 1650 1660 1670 1680 1690
1560 1570 1580 1590 1600 1610
pF1KB7 KSSSANSKIGSSAPTTTAANTSLMGIKMTTVALSSTSQTATALTVPAISSASTHKTIKNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSSSANSKIGSSAPTTTAANTSLMGIKMTTVALSSTSQTATALTVPAISSASTHKTIKNP
1700 1710 1720 1730 1740 1750
1620 1630 1640 1650 1660 1670
pF1KB7 VNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQSTWGPFPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQSTWGPFPV
1760 1770 1780 1790 1800 1810
1680 1690 1700 1710 1720 1730
pF1KB7 RPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGTSTNGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGTSTNGSP
1820 1830 1840 1850 1860 1870
1740 1750 1760 1770 1780 1790
pF1KB7 SSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMPTAKEHYPVSSPSSPSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMPTAKEHYPVSSPSSPSPP
1880 1890 1900 1910 1920 1930
1800 1810 1820 1830 1840 1850
pF1KB7 AQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTNTRPPNSSSSSGSSSAHSNQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTNTRPPNSSSSSGSSSAHSNQQ
1940 1950 1960 1970 1980 1990
1860 1870 1880 1890 1900 1910
pF1KB7 QPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYPMPQTPMGCPQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYPMPQTPMGCPQP
2000 2010 2020 2030 2040 2050
1920 1930 1940 1950 1960 1970
pF1KB7 TPKMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNHIKRPHSVPSSVQLPSTLSTQSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPKMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNHIKRPHSVPSSVQLPSTLSTQSA
2060 2070 2080 2090 2100 2110
1980 1990 2000 2010 2020 2030
pF1KB7 CQNSVHPANKPIAPNFSAPLPFGPFSTLFENSPTSAHAFWGGSVVSSQSTPESMLSGKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQNSVHPANKPIAPNFSAPLPFGPFSTLFENSPTSAHAFWGGSVVSSQSTPESMLSGKSS
2120 2130 2140 2150 2160 2170
2040 2050 2060 2070 2080 2090
pF1KB7 YLPNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDSPYGSVTPSSTHLGNFASNISGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLPNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDSPYGSVTPSSTHLGNFASNISGG
2180 2190 2200 2210 2220 2230
2100 2110 2120 2130 2140 2150
pF1KB7 QMYGPGAPLGGAPAAANFNRQHFSPLSLLTPCSSASNDSSAQSVSSGVRAPSPAPSSVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QMYGPGAPLGGAPAAANFNRQHFSPLSLLTPCSSASNDSSAQSVSSGVRAPSPAPSSVPL
2240 2250 2260 2270 2280 2290
2160 2170 2180 2190 2200 2210
pF1KB7 GSEKPSNVSQDRKVPVPIGTERSARIRQTGTSAPSVIGSNLSTSVGHSGIWSFEGIGGNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSEKPSNVSQDRKVPVPIGTERSARIRQTGTSAPSVIGSNLSTSVGHSGIWSFEGIGGNQ
2300 2310 2320 2330 2340 2350
2220 2230 2240 2250 2260 2270
pF1KB7 DKVDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGIVTPSGTFHQHVPAGYMDFPKVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKVDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGIVTPSGTFHQHVPAGYMDFPKVG
2360 2370 2380 2390 2400 2410
2280 2290 2300 2310 2320 2330
pF1KB7 GMPFSVYGNAMIPPVAPIPDGAGGPIFNGPHAADPSWNSLIKMVSSSTENNGPQTVWTGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMPFSVYGNAMIPPVAPIPDGAGGPIFNGPHAADPSWNSLIKMVSSSTENNGPQTVWTGP
2420 2430 2440 2450 2460 2470
2340 2350
pF1KB7 WAPHMNSVHMNQLG
::::::::::::::
NP_001 WAPHMNSVHMNQLG
2480 2490
>--
initn: 553 init1: 553 opt: 553 Z-score: 215.5 bits: 53.9 E(85289): 2.9e-05
Smith-Waterman score: 553; 96.8% identity (98.9% similar) in 93 aa overlap (127-219:14-106)
100 110 120 130 140 150
pF1KB7 GGGGGGGGGGGGGGTSSNNSEEEEDDDDEEEEVSEVESFILDQDDLENPMLETASKLLLS
:.. ::::::::::::::::::::::::::
NP_001 MVETAAEMEAYVLEDILEVESFILDQDDLENPMLETASKLLLS
10 20 30 40
160 170 180 190 200 210
pF1KB7 GTADGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTADGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAA
50 60 70 80 90 100
220 230 240 250 260 270
pF1KB7 AALTRMRAESTANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACS
:::
NP_001 AALTRMRAESTANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACS
110 120 130 140 150 160
>>NP_115593 (OMIM: 615929) ankyrin repeat domain-contain (2603 aa)
initn: 10333 init1: 10333 opt: 10338 Z-score: 3690.9 bits: 697.1 E(85289): 7.6e-199
Smith-Waterman score: 13449; 89.5% identity (89.5% similar) in 2384 aa overlap (220-2352:220-2603)
190 200 210 220 230 240
pF1KB7 ADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAEACSEGDVNA
::::::::::::::::::::::::::::::
NP_115 ADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAEACSEGDVNA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 VRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 NGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 NGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 PLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 PLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 KTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 KTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIER
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 GASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 ADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 ADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 TDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 TDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 LACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPPP
670 680 690 700 710 720
730 740 750 760 770
pF1KB7 DVTQLTPPSHDLNRAPRVPVQALPMVVPPQEPDKPPANVATTLPIRNKA-----------
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 DVTQLTPPSHDLNRAPRVPVQALPMVVPPQEPDKPPANVATTLPIRNKAASKQKSSSHLP
730 740 750 760 770 780
pF1KB7 ------------------------------------------------------------
NP_115 ANSQDVQGYITNQSPESIVEEAQGKLTELEQRIKEAIEKNAQLQSLELAHADQLTKEKIE
790 800 810 820 830 840
pF1KB7 ------------------------------------------------------------
NP_115 ELNKTREEQIQKKQKILEELQKVERELQLKTQQQLKKQYLEVKAQRIQLQQQQQQSCQHL
850 860 870 880 890 900
pF1KB7 ------------------------------------------------------------
NP_115 GLLTPVGVGEQLSEGDYARLQQVDPVLLKDEPQQTAAQMGFAPIQPLAMPQALPLAAGPL
910 920 930 940 950 960
pF1KB7 ------------------------------------------------------------
NP_115 PPGSIANLTELQGVIVGQPVLGQAQLAGLGQGILTETQQGLMVASPAQTLNDTLDDIMAA
970 980 990 1000 1010 1020
780 790 800 810 820 830
pF1KB7 VSGRASAMSNTPTHSIAASISQPQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 VSGRASAMSNTPTHSIAASISQPQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTL
1030 1040 1050 1060 1070 1080
840 850 860 870 880 890
pF1KB7 ACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 ACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERT
1090 1100 1110 1120 1130 1140
900 910 920 930 940 950
pF1KB7 KDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 KDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEI
1150 1160 1170 1180 1190 1200
960 970 980 990 1000 1010
pF1KB7 NSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 NSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVS
1210 1220 1230 1240 1250 1260
1020 1030 1040 1050 1060 1070
pF1KB7 LLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAAD
1270 1280 1290 1300 1310 1320
1080 1090 1100 1110 1120 1130
pF1KB7 KGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 KGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITP
1330 1340 1350 1360 1370 1380
1140 1150 1160 1170 1180 1190
pF1KB7 LMAAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LMAAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQA
1390 1400 1410 1420 1430 1440
1200 1210 1220 1230 1240 1250
pF1KB7 AEANKNASILLEELDLEKLREESRRLALAAKREKRKEKRRKKKEEQRRKLEEIEAKNKEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 AEANKNASILLEELDLEKLREESRRLALAAKREKRKEKRRKKKEEQRRKLEEIEAKNKEN
1450 1460 1470 1480 1490 1500
1260 1270 1280 1290 1300 1310
pF1KB7 FELQAAQEKEKLKVEDEPEVLTEPPSATTTTTIGISATWTTLAGSHGKRNNTITTTSSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 FELQAAQEKEKLKVEDEPEVLTEPPSATTTTTIGISATWTTLAGSHGKRNNTITTTSSKR
1510 1520 1530 1540 1550 1560
1320 1330 1340 1350 1360 1370
pF1KB7 KNRKNKITPENVQIIFDDPLPISYSQPEKVNGESKSSSTSESGDSDNMRISSCSDESSNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 KNRKNKITPENVQIIFDDPLPISYSQPEKVNGESKSSSTSESGDSDNMRISSCSDESSNS
1570 1580 1590 1600 1610 1620
1380 1390 1400 1410 1420 1430
pF1KB7 NSSRKSDNHSPAVVTTTVSSKKQPSVLVTFPKEERKSVSGKASIKLSETISEGTSNSLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 NSSRKSDNHSPAVVTTTVSSKKQPSVLVTFPKEERKSVSGKASIKLSETISEGTSNSLST
1630 1640 1650 1660 1670 1680
1440 1450 1460 1470 1480 1490
pF1KB7 CTKSGPSPLSSPNGKLTVASPKRGQKREEGWKEVVRRSKKVSVPSTVISRVIGRGGCNIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 CTKSGPSPLSSPNGKLTVASPKRGQKREEGWKEVVRRSKKVSVPSTVISRVIGRGGCNIN
1690 1700 1710 1720 1730 1740
1500 1510 1520 1530 1540 1550
pF1KB7 AIREFTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALIKDPDKEIDELIPKNRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 AIREFTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALIKDPDKEIDELIPKNRL
1750 1760 1770 1780 1790 1800
1560 1570 1580 1590 1600 1610
pF1KB7 KSSSANSKIGSSAPTTTAANTSLMGIKMTTVALSSTSQTATALTVPAISSASTHKTIKNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 KSSSANSKIGSSAPTTTAANTSLMGIKMTTVALSSTSQTATALTVPAISSASTHKTIKNP
1810 1820 1830 1840 1850 1860
1620 1630 1640 1650 1660 1670
pF1KB7 VNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQSTWGPFPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 VNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQSTWGPFPV
1870 1880 1890 1900 1910 1920
1680 1690 1700 1710 1720 1730
pF1KB7 RPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGTSTNGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 RPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGTSTNGSP
1930 1940 1950 1960 1970 1980
1740 1750 1760 1770 1780 1790
pF1KB7 SSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMPTAKEHYPVSSPSSPSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 SSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMPTAKEHYPVSSPSSPSPP
1990 2000 2010 2020 2030 2040
1800 1810 1820 1830 1840 1850
pF1KB7 AQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTNTRPPNSSSSSGSSSAHSNQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 AQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTNTRPPNSSSSSGSSSAHSNQQ
2050 2060 2070 2080 2090 2100
1860 1870 1880 1890 1900 1910
pF1KB7 QPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYPMPQTPMGCPQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 QPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYPMPQTPMGCPQP
2110 2120 2130 2140 2150 2160
1920 1930 1940 1950 1960 1970
pF1KB7 TPKMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNHIKRPHSVPSSVQLPSTLSTQSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 TPKMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNHIKRPHSVPSSVQLPSTLSTQSA
2170 2180 2190 2200 2210 2220
1980 1990 2000 2010 2020 2030
pF1KB7 CQNSVHPANKPIAPNFSAPLPFGPFSTLFENSPTSAHAFWGGSVVSSQSTPESMLSGKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 CQNSVHPANKPIAPNFSAPLPFGPFSTLFENSPTSAHAFWGGSVVSSQSTPESMLSGKSS
2230 2240 2250 2260 2270 2280
2040 2050 2060 2070 2080 2090
pF1KB7 YLPNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDSPYGSVTPSSTHLGNFASNISGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 YLPNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDSPYGSVTPSSTHLGNFASNISGG
2290 2300 2310 2320 2330 2340
2100 2110 2120 2130 2140 2150
pF1KB7 QMYGPGAPLGGAPAAANFNRQHFSPLSLLTPCSSASNDSSAQSVSSGVRAPSPAPSSVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 QMYGPGAPLGGAPAAANFNRQHFSPLSLLTPCSSASNDSSAQSVSSGVRAPSPAPSSVPL
2350 2360 2370 2380 2390 2400
2160 2170 2180 2190 2200 2210
pF1KB7 GSEKPSNVSQDRKVPVPIGTERSARIRQTGTSAPSVIGSNLSTSVGHSGIWSFEGIGGNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GSEKPSNVSQDRKVPVPIGTERSARIRQTGTSAPSVIGSNLSTSVGHSGIWSFEGIGGNQ
2410 2420 2430 2440 2450 2460
2220 2230 2240 2250 2260 2270
pF1KB7 DKVDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGIVTPSGTFHQHVPAGYMDFPKVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 DKVDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGIVTPSGTFHQHVPAGYMDFPKVG
2470 2480 2490 2500 2510 2520
2280 2290 2300 2310 2320 2330
pF1KB7 GMPFSVYGNAMIPPVAPIPDGAGGPIFNGPHAADPSWNSLIKMVSSSTENNGPQTVWTGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GMPFSVYGNAMIPPVAPIPDGAGGPIFNGPHAADPSWNSLIKMVSSSTENNGPQTVWTGP
2530 2540 2550 2560 2570 2580
2340 2350
pF1KB7 WAPHMNSVHMNQLG
::::::::::::::
NP_115 WAPHMNSVHMNQLG
2590 2600
>--
initn: 1414 init1: 1414 opt: 1414 Z-score: 521.0 bits: 110.5 E(85289): 2.8e-22
Smith-Waterman score: 1414; 100.0% identity (100.0% similar) in 219 aa overlap (1-219:1-219)
10 20 30 40 50 60
pF1KB7 MEKATVPVAAATAAEGEGSPPAVAAVAGPPAAAEVGGGVGGSSRARSASSPRGMVRVCDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MEKATVPVAAATAAEGEGSPPAVAAVAGPPAAAEVGGGVGGSSRARSASSPRGMVRVCDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 LLKKKPPQQQHHKAKRNRTCRPPSSSESSSDSDNSGGGGGGGGGGGGGGGTSSNNSEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LLKKKPPQQQHHKAKRNRTCRPPSSSESSSDSDNSGGGGGGGGGGGGGGGTSSNNSEEEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 DDDDEEEEVSEVESFILDQDDLENPMLETASKLLLSGTADGADLRTVDPETQARLEALLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 DDDDEEEEVSEVESFILDQDDLENPMLETASKLLLSGTADGADLRTVDPETQARLEALLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 AAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAE
:::::::::::::::::::::::::::::::::::::::
NP_115 AAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG
NP_115 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG
250 260 270 280 290 300
>>XP_016863500 (OMIM: 615929) PREDICTED: ankyrin repeat (2489 aa)
initn: 10333 init1: 10333 opt: 10333 Z-score: 3689.4 bits: 696.7 E(85289): 9.2e-199
Smith-Waterman score: 13456; 89.5% identity (89.5% similar) in 2384 aa overlap (219-2352:106-2489)
190 200 210 220 230 240
pF1KB7 TADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAEACSEGDVN
::::::::::::::::::::::::::::::
XP_016 TADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAEACSEGDVN
80 90 100 110 120 130
250 260 270 280 290 300
pF1KB7 AVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAA
140 150 160 170 180 190
310 320 330 340 350 360
pF1KB7 ANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGH
200 210 220 230 240 250
370 380 390 400 410 420
pF1KB7 TPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQE
260 270 280 290 300 310
430 440 450 460 470 480
pF1KB7 HKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIE
320 330 340 350 360 370
490 500 510 520 530 540
pF1KB7 RGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLE
380 390 400 410 420 430
550 560 570 580 590 600
pF1KB7 VADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENG
440 450 460 470 480 490
610 620 630 640 650 660
pF1KB7 HTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVL
500 510 520 530 540 550
670 680 690 700 710 720
pF1KB7 SLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPP
560 570 580 590 600 610
730 740 750 760 770
pF1KB7 PDVTQLTPPSHDLNRAPRVPVQALPMVVPPQEPDKPPANVATTLPIRNKA----------
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDVTQLTPPSHDLNRAPRVPVQALPMVVPPQEPDKPPANVATTLPIRNKAASKQKSSSHL
620 630 640 650 660 670
pF1KB7 ------------------------------------------------------------
XP_016 PANSQDVQGYITNQSPESIVEEAQGKLTELEQRIKEAIEKNAQLQSLELAHADQLTKEKI
680 690 700 710 720 730
pF1KB7 ------------------------------------------------------------
XP_016 EELNKTREEQIQKKQKILEELQKVERELQLKTQQQLKKQYLEVKAQRIQLQQQQQQSCQH
740 750 760 770 780 790
pF1KB7 ------------------------------------------------------------
XP_016 LGLLTPVGVGEQLSEGDYARLQQVDPVLLKDEPQQTAAQMGFAPIQPLAMPQALPLAAGP
800 810 820 830 840 850
pF1KB7 ------------------------------------------------------------
XP_016 LPPGSIANLTELQGVIVGQPVLGQAQLAGLGQGILTETQQGLMVASPAQTLNDTLDDIMA
860 870 880 890 900 910
780 790 800 810 820 830
pF1KB7 VSGRASAMSNTPTHSIAASISQPQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSGRASAMSNTPTHSIAASISQPQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTL
920 930 940 950 960 970
840 850 860 870 880 890
pF1KB7 ACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERT
980 990 1000 1010 1020 1030
900 910 920 930 940 950
pF1KB7 KDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEI
1040 1050 1060 1070 1080 1090
960 970 980 990 1000 1010
pF1KB7 NSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVS
1100 1110 1120 1130 1140 1150
1020 1030 1040 1050 1060 1070
pF1KB7 LLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAAD
1160 1170 1180 1190 1200 1210
1080 1090 1100 1110 1120 1130
pF1KB7 KGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITP
1220 1230 1240 1250 1260 1270
1140 1150 1160 1170 1180 1190
pF1KB7 LMAAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMAAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQA
1280 1290 1300 1310 1320 1330
1200 1210 1220 1230 1240 1250
pF1KB7 AEANKNASILLEELDLEKLREESRRLALAAKREKRKEKRRKKKEEQRRKLEEIEAKNKEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEANKNASILLEELDLEKLREESRRLALAAKREKRKEKRRKKKEEQRRKLEEIEAKNKEN
1340 1350 1360 1370 1380 1390
1260 1270 1280 1290 1300 1310
pF1KB7 FELQAAQEKEKLKVEDEPEVLTEPPSATTTTTIGISATWTTLAGSHGKRNNTITTTSSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FELQAAQEKEKLKVEDEPEVLTEPPSATTTTTIGISATWTTLAGSHGKRNNTITTTSSKR
1400 1410 1420 1430 1440 1450
1320 1330 1340 1350 1360 1370
pF1KB7 KNRKNKITPENVQIIFDDPLPISYSQPEKVNGESKSSSTSESGDSDNMRISSCSDESSNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNRKNKITPENVQIIFDDPLPISYSQPEKVNGESKSSSTSESGDSDNMRISSCSDESSNS
1460 1470 1480 1490 1500 1510
1380 1390 1400 1410 1420 1430
pF1KB7 NSSRKSDNHSPAVVTTTVSSKKQPSVLVTFPKEERKSVSGKASIKLSETISEGTSNSLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSRKSDNHSPAVVTTTVSSKKQPSVLVTFPKEERKSVSGKASIKLSETISEGTSNSLST
1520 1530 1540 1550 1560 1570
1440 1450 1460 1470 1480 1490
pF1KB7 CTKSGPSPLSSPNGKLTVASPKRGQKREEGWKEVVRRSKKVSVPSTVISRVIGRGGCNIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTKSGPSPLSSPNGKLTVASPKRGQKREEGWKEVVRRSKKVSVPSTVISRVIGRGGCNIN
1580 1590 1600 1610 1620 1630
1500 1510 1520 1530 1540 1550
pF1KB7 AIREFTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALIKDPDKEIDELIPKNRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIREFTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALIKDPDKEIDELIPKNRL
1640 1650 1660 1670 1680 1690
1560 1570 1580 1590 1600 1610
pF1KB7 KSSSANSKIGSSAPTTTAANTSLMGIKMTTVALSSTSQTATALTVPAISSASTHKTIKNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSSSANSKIGSSAPTTTAANTSLMGIKMTTVALSSTSQTATALTVPAISSASTHKTIKNP
1700 1710 1720 1730 1740 1750
1620 1630 1640 1650 1660 1670
pF1KB7 VNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQSTWGPFPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQSTWGPFPV
1760 1770 1780 1790 1800 1810
1680 1690 1700 1710 1720 1730
pF1KB7 RPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGTSTNGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGTSTNGSP
1820 1830 1840 1850 1860 1870
1740 1750 1760 1770 1780 1790
pF1KB7 SSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMPTAKEHYPVSSPSSPSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMPTAKEHYPVSSPSSPSPP
1880 1890 1900 1910 1920 1930
1800 1810 1820 1830 1840 1850
pF1KB7 AQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTNTRPPNSSSSSGSSSAHSNQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTNTRPPNSSSSSGSSSAHSNQQ
1940 1950 1960 1970 1980 1990
1860 1870 1880 1890 1900 1910
pF1KB7 QPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYPMPQTPMGCPQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYPMPQTPMGCPQP
2000 2010 2020 2030 2040 2050
1920 1930 1940 1950 1960 1970
pF1KB7 TPKMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNHIKRPHSVPSSVQLPSTLSTQSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPKMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNHIKRPHSVPSSVQLPSTLSTQSA
2060 2070 2080 2090 2100 2110
1980 1990 2000 2010 2020 2030
pF1KB7 CQNSVHPANKPIAPNFSAPLPFGPFSTLFENSPTSAHAFWGGSVVSSQSTPESMLSGKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQNSVHPANKPIAPNFSAPLPFGPFSTLFENSPTSAHAFWGGSVVSSQSTPESMLSGKSS
2120 2130 2140 2150 2160 2170
2040 2050 2060 2070 2080 2090
pF1KB7 YLPNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDSPYGSVTPSSTHLGNFASNISGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLPNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDSPYGSVTPSSTHLGNFASNISGG
2180 2190 2200 2210 2220 2230
2100 2110 2120 2130 2140 2150
pF1KB7 QMYGPGAPLGGAPAAANFNRQHFSPLSLLTPCSSASNDSSAQSVSSGVRAPSPAPSSVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMYGPGAPLGGAPAAANFNRQHFSPLSLLTPCSSASNDSSAQSVSSGVRAPSPAPSSVPL
2240 2250 2260 2270 2280 2290
2160 2170 2180 2190 2200 2210
pF1KB7 GSEKPSNVSQDRKVPVPIGTERSARIRQTGTSAPSVIGSNLSTSVGHSGIWSFEGIGGNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSEKPSNVSQDRKVPVPIGTERSARIRQTGTSAPSVIGSNLSTSVGHSGIWSFEGIGGNQ
2300 2310 2320 2330 2340 2350
2220 2230 2240 2250 2260 2270
pF1KB7 DKVDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGIVTPSGTFHQHVPAGYMDFPKVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKVDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGIVTPSGTFHQHVPAGYMDFPKVG
2360 2370 2380 2390 2400 2410
2280 2290 2300 2310 2320 2330
pF1KB7 GMPFSVYGNAMIPPVAPIPDGAGGPIFNGPHAADPSWNSLIKMVSSSTENNGPQTVWTGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GMPFSVYGNAMIPPVAPIPDGAGGPIFNGPHAADPSWNSLIKMVSSSTENNGPQTVWTGP
2420 2430 2440 2450 2460 2470
2340 2350
pF1KB7 WAPHMNSVHMNQLG
::::::::::::::
XP_016 WAPHMNSVHMNQLG
2480
>--
initn: 548 init1: 548 opt: 548 Z-score: 213.7 bits: 53.6 E(85289): 3.6e-05
Smith-Waterman score: 548; 96.7% identity (98.9% similar) in 92 aa overlap (127-218:14-105)
100 110 120 130 140 150
pF1KB7 GGGGGGGGGGGGGGTSSNNSEEEEDDDDEEEEVSEVESFILDQDDLENPMLETASKLLLS
:.. ::::::::::::::::::::::::::
XP_016 MVETAAEMEAYVLEDILEVESFILDQDDLENPMLETASKLLLS
10 20 30 40
160 170 180 190 200 210
pF1KB7 GTADGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTADGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAA
50 60 70 80 90 100
220 230 240 250 260 270
pF1KB7 AALTRMRAESTANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACS
::
XP_016 AALTRMRAESTANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACS
110 120 130 140 150 160
>>NP_056389 (OMIM: 615929) ankyrin repeat domain-contain (2602 aa)
initn: 10333 init1: 10333 opt: 10333 Z-score: 3689.2 bits: 696.7 E(85289): 9.5e-199
Smith-Waterman score: 13456; 89.5% identity (89.5% similar) in 2384 aa overlap (219-2352:219-2602)
190 200 210 220 230 240
pF1KB7 TADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAEACSEGDVN
::::::::::::::::::::::::::::::
NP_056 TADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAEACSEGDVN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 AVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 TPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 HKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 RGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 VADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 HTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 SLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPP
670 680 690 700 710 720
730 740 750 760 770
pF1KB7 PDVTQLTPPSHDLNRAPRVPVQALPMVVPPQEPDKPPANVATTLPIRNKA----------
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PDVTQLTPPSHDLNRAPRVPVQALPMVVPPQEPDKPPANVATTLPIRNKAASKQKSSSHL
730 740 750 760 770 780
pF1KB7 ------------------------------------------------------------
NP_056 PANSQDVQGYITNQSPESIVEEAQGKLTELEQRIKEAIEKNAQLQSLELAHADQLTKEKI
790 800 810 820 830 840
pF1KB7 ------------------------------------------------------------
NP_056 EELNKTREEQIQKKQKILEELQKVERELQLKTQQQLKKQYLEVKAQRIQLQQQQQQSCQH
850 860 870 880 890 900
pF1KB7 ------------------------------------------------------------
NP_056 LGLLTPVGVGEQLSEGDYARLQQVDPVLLKDEPQQTAAQMGFAPIQPLAMPQALPLAAGP
910 920 930 940 950 960
pF1KB7 ------------------------------------------------------------
NP_056 LPPGSIANLTELQGVIVGQPVLGQAQLAGLGQGILTETQQGLMVASPAQTLNDTLDDIMA
970 980 990 1000 1010 1020
780 790 800 810 820 830
pF1KB7 VSGRASAMSNTPTHSIAASISQPQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VSGRASAMSNTPTHSIAASISQPQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTL
1030 1040 1050 1060 1070 1080
840 850 860 870 880 890
pF1KB7 ACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERT
1090 1100 1110 1120 1130 1140
900 910 920 930 940 950
pF1KB7 KDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEI
1150 1160 1170 1180 1190 1200
960 970 980 990 1000 1010
pF1KB7 NSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVS
1210 1220 1230 1240 1250 1260
1020 1030 1040 1050 1060 1070
pF1KB7 LLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAAD
1270 1280 1290 1300 1310 1320
1080 1090 1100 1110 1120 1130
pF1KB7 KGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITP
1330 1340 1350 1360 1370 1380
1140 1150 1160 1170 1180 1190
pF1KB7 LMAAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LMAAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQA
1390 1400 1410 1420 1430 1440
1200 1210 1220 1230 1240 1250
pF1KB7 AEANKNASILLEELDLEKLREESRRLALAAKREKRKEKRRKKKEEQRRKLEEIEAKNKEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AEANKNASILLEELDLEKLREESRRLALAAKREKRKEKRRKKKEEQRRKLEEIEAKNKEN
1450 1460 1470 1480 1490 1500
1260 1270 1280 1290 1300 1310
pF1KB7 FELQAAQEKEKLKVEDEPEVLTEPPSATTTTTIGISATWTTLAGSHGKRNNTITTTSSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FELQAAQEKEKLKVEDEPEVLTEPPSATTTTTIGISATWTTLAGSHGKRNNTITTTSSKR
1510 1520 1530 1540 1550 1560
1320 1330 1340 1350 1360 1370
pF1KB7 KNRKNKITPENVQIIFDDPLPISYSQPEKVNGESKSSSTSESGDSDNMRISSCSDESSNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KNRKNKITPENVQIIFDDPLPISYSQPEKVNGESKSSSTSESGDSDNMRISSCSDESSNS
1570 1580 1590 1600 1610 1620
1380 1390 1400 1410 1420 1430
pF1KB7 NSSRKSDNHSPAVVTTTVSSKKQPSVLVTFPKEERKSVSGKASIKLSETISEGTSNSLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NSSRKSDNHSPAVVTTTVSSKKQPSVLVTFPKEERKSVSGKASIKLSETISEGTSNSLST
1630 1640 1650 1660 1670 1680
1440 1450 1460 1470 1480 1490
pF1KB7 CTKSGPSPLSSPNGKLTVASPKRGQKREEGWKEVVRRSKKVSVPSTVISRVIGRGGCNIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 CTKSGPSPLSSPNGKLTVASPKRGQKREEGWKEVVRRSKKVSVPSTVISRVIGRGGCNIN
1690 1700 1710 1720 1730 1740
1500 1510 1520 1530 1540 1550
pF1KB7 AIREFTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALIKDPDKEIDELIPKNRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AIREFTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALIKDPDKEIDELIPKNRL
1750 1760 1770 1780 1790 1800
1560 1570 1580 1590 1600 1610
pF1KB7 KSSSANSKIGSSAPTTTAANTSLMGIKMTTVALSSTSQTATALTVPAISSASTHKTIKNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KSSSANSKIGSSAPTTTAANTSLMGIKMTTVALSSTSQTATALTVPAISSASTHKTIKNP
1810 1820 1830 1840 1850 1860
1620 1630 1640 1650 1660 1670
pF1KB7 VNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQSTWGPFPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQSTWGPFPV
1870 1880 1890 1900 1910 1920
1680 1690 1700 1710 1720 1730
pF1KB7 RPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGTSTNGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGTSTNGSP
1930 1940 1950 1960 1970 1980
1740 1750 1760 1770 1780 1790
pF1KB7 SSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMPTAKEHYPVSSPSSPSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMPTAKEHYPVSSPSSPSPP
1990 2000 2010 2020 2030 2040
1800 1810 1820 1830 1840 1850
pF1KB7 AQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTNTRPPNSSSSSGSSSAHSNQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTNTRPPNSSSSSGSSSAHSNQQ
2050 2060 2070 2080 2090 2100
1860 1870 1880 1890 1900 1910
pF1KB7 QPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYPMPQTPMGCPQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYPMPQTPMGCPQP
2110 2120 2130 2140 2150 2160
1920 1930 1940 1950 1960 1970
pF1KB7 TPKMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNHIKRPHSVPSSVQLPSTLSTQSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TPKMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNHIKRPHSVPSSVQLPSTLSTQSA
2170 2180 2190 2200 2210 2220
1980 1990 2000 2010 2020 2030
pF1KB7 CQNSVHPANKPIAPNFSAPLPFGPFSTLFENSPTSAHAFWGGSVVSSQSTPESMLSGKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 CQNSVHPANKPIAPNFSAPLPFGPFSTLFENSPTSAHAFWGGSVVSSQSTPESMLSGKSS
2230 2240 2250 2260 2270 2280
2040 2050 2060 2070 2080 2090
pF1KB7 YLPNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDSPYGSVTPSSTHLGNFASNISGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 YLPNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDSPYGSVTPSSTHLGNFASNISGG
2290 2300 2310 2320 2330 2340
2100 2110 2120 2130 2140 2150
pF1KB7 QMYGPGAPLGGAPAAANFNRQHFSPLSLLTPCSSASNDSSAQSVSSGVRAPSPAPSSVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QMYGPGAPLGGAPAAANFNRQHFSPLSLLTPCSSASNDSSAQSVSSGVRAPSPAPSSVPL
2350 2360 2370 2380 2390 2400
2160 2170 2180 2190 2200 2210
pF1KB7 GSEKPSNVSQDRKVPVPIGTERSARIRQTGTSAPSVIGSNLSTSVGHSGIWSFEGIGGNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GSEKPSNVSQDRKVPVPIGTERSARIRQTGTSAPSVIGSNLSTSVGHSGIWSFEGIGGNQ
2410 2420 2430 2440 2450 2460
2220 2230 2240 2250 2260 2270
pF1KB7 DKVDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGIVTPSGTFHQHVPAGYMDFPKVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DKVDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGIVTPSGTFHQHVPAGYMDFPKVG
2470 2480 2490 2500 2510 2520
2280 2290 2300 2310 2320 2330
pF1KB7 GMPFSVYGNAMIPPVAPIPDGAGGPIFNGPHAADPSWNSLIKMVSSSTENNGPQTVWTGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GMPFSVYGNAMIPPVAPIPDGAGGPIFNGPHAADPSWNSLIKMVSSSTENNGPQTVWTGP
2530 2540 2550 2560 2570 2580
2340 2350
pF1KB7 WAPHMNSVHMNQLG
::::::::::::::
NP_056 WAPHMNSVHMNQLG
2590 2600
>--
initn: 1409 init1: 1409 opt: 1409 Z-score: 519.3 bits: 110.2 E(85289): 3.5e-22
Smith-Waterman score: 1409; 100.0% identity (100.0% similar) in 218 aa overlap (1-218:1-218)
10 20 30 40 50 60
pF1KB7 MEKATVPVAAATAAEGEGSPPAVAAVAGPPAAAEVGGGVGGSSRARSASSPRGMVRVCDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MEKATVPVAAATAAEGEGSPPAVAAVAGPPAAAEVGGGVGGSSRARSASSPRGMVRVCDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 LLKKKPPQQQHHKAKRNRTCRPPSSSESSSDSDNSGGGGGGGGGGGGGGGTSSNNSEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LLKKKPPQQQHHKAKRNRTCRPPSSSESSSDSDNSGGGGGGGGGGGGGGGTSSNNSEEEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 DDDDEEEEVSEVESFILDQDDLENPMLETASKLLLSGTADGADLRTVDPETQARLEALLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DDDDEEEEVSEVESFILDQDDLENPMLETASKLLLSGTADGADLRTVDPETQARLEALLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 AAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAE
::::::::::::::::::::::::::::::::::::::
NP_056 AAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG
NP_056 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG
250 260 270 280 290 300
>>XP_016863505 (OMIM: 615929) PREDICTED: ankyrin repeat (1229 aa)
initn: 7847 init1: 7847 opt: 7847 Z-score: 2810.5 bits: 533.1 E(85289): 8.3e-150
Smith-Waterman score: 7847; 100.0% identity (100.0% similar) in 1216 aa overlap (1-1216:1-1216)
10 20 30 40 50 60
pF1KB7 MEKATVPVAAATAAEGEGSPPAVAAVAGPPAAAEVGGGVGGSSRARSASSPRGMVRVCDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEKATVPVAAATAAEGEGSPPAVAAVAGPPAAAEVGGGVGGSSRARSASSPRGMVRVCDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 LLKKKPPQQQHHKAKRNRTCRPPSSSESSSDSDNSGGGGGGGGGGGGGGGTSSNNSEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKKKPPQQQHHKAKRNRTCRPPSSSESSSDSDNSGGGGGGGGGGGGGGGTSSNNSEEEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 DDDDEEEEVSEVESFILDQDDLENPMLETASKLLLSGTADGADLRTVDPETQARLEALLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDDDEEEEVSEVESFILDQDDLENPMLETASKLLLSGTADGADLRTVDPETQARLEALLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 AAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 DITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 LEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 ELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 ACCGGFLEVADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACCGGFLEVADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 LTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 ANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 NNLLSAPPPDVTQLTPPSHDLNRAPRVPVQALPMVVPPQEPDKPPANVATTLPIRNKAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNLLSAPPPDVTQLTPPSHDLNRAPRVPVQALPMVVPPQEPDKPPANVATTLPIRNKAVS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 GRASAMSNTPTHSIAASISQPQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTLAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRASAMSNTPTHSIAASISQPQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTLAC
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 AGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 TPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 RTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB7 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB7 HYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLM
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB7 AAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQAAE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB7 ANKNASILLEELDLEKLREESRRLALAAKREKRKEKRRKKKEEQRRKLEEIEAKNKENFE
::::::::::::::::
XP_016 ANKNASILLEELDLEKADYNIIPIYSHGE
1210 1220
>>XP_016863506 (OMIM: 615929) PREDICTED: ankyrin repeat (1116 aa)
initn: 6986 init1: 6986 opt: 6986 Z-score: 2505.3 bits: 476.5 E(85289): 8.3e-133
Smith-Waterman score: 6986; 99.7% identity (99.9% similar) in 1090 aa overlap (127-1216:14-1103)
100 110 120 130 140 150
pF1KB7 GGGGGGGGGGGGGGTSSNNSEEEEDDDDEEEEVSEVESFILDQDDLENPMLETASKLLLS
:.. ::::::::::::::::::::::::::
XP_016 MVETAAEMEAYVLEDILEVESFILDQDDLENPMLETASKLLLS
10 20 30 40
160 170 180 190 200 210
pF1KB7 GTADGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTADGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAA
50 60 70 80 90 100
220 230 240 250 260 270
pF1KB7 AALTRMRAESTANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AALTRMRAESTANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACS
110 120 130 140 150 160
280 290 300 310 320 330
pF1KB7 AGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNT
170 180 190 200 210 220
340 350 360 370 380 390
pF1KB7 ALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTH
230 240 250 260 270 280
400 410 420 430 440 450
pF1KB7 SNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDS
290 300 310 320 330 340
460 470 480 490 500 510
pF1KB7 GAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMV
350 360 370 380 390 400
520 530 540 550 560 570
pF1KB7 ALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADIELGCSTPLMEAAQEGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADIELGCSTPLMEAAQEGH
410 420 430 440 450 460
580 590 600 610 620 630
pF1KB7 LELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMK
470 480 490 500 510 520
640 650 660 670 680 690
pF1KB7 AARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKD
530 540 550 560 570 580
700 710 720 730 740 750
pF1KB7 GSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPPPDVTQLTPPSHDLNRAPRVPVQALPMVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPPPDVTQLTPPSHDLNRAPRVPVQALPMVV
590 600 610 620 630 640
760 770 780 790 800 810
pF1KB7 PPQEPDKPPANVATTLPIRNKAVSGRASAMSNTPTHSIAASISQPQTPTPSPIISPSAML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPQEPDKPPANVATTLPIRNKAVSGRASAMSNTPTHSIAASISQPQTPTPSPIISPSAML
650 660 670 680 690 700
820 830 840 850 860 870
pF1KB7 PIYPAIDIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIYPAIDIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAG
710 720 730 740 750 760
880 890 900 910 920 930
pF1KB7 HVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPL
770 780 790 800 810 820
940 950 960 970 980 990
pF1KB7 SLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQ
830 840 850 860 870 880
1000 1010 1020 1030 1040 1050
pF1KB7 IETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDK
890 900 910 920 930 940
1060 1070 1080 1090 1100 1110
pF1KB7 GADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLD
950 960 970 980 990 1000
1120 1130 1140 1150 1160 1170
pF1KB7 VVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITD
1010 1020 1030 1040 1050 1060
1180 1190 1200 1210 1220 1230
pF1KB7 KEMLKKCHLCMESIVQAKDRQAAEANKNASILLEELDLEKLREESRRLALAAKREKRKEK
::::::::::::::::::::::::::::::::::::::::
XP_016 KEMLKKCHLCMESIVQAKDRQAAEANKNASILLEELDLEKADYNIIPIYSHGE
1070 1080 1090 1100 1110
1240 1250 1260 1270 1280 1290
pF1KB7 RRKKKEEQRRKLEEIEAKNKENFELQAAQEKEKLKVEDEPEVLTEPPSATTTTTIGISAT
2352 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 13:32:25 2016 done: Sat Nov 5 13:32:28 2016
Total Scan time: 20.020 Total Display time: 1.640
Function used was FASTA [36.3.4 Apr, 2011]