Result of FASTA (omim) for
pFN21AB5635
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5635, 474 aa
1>>>pF1KB5635 474 - 474 aa - 474 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9915+/-0.000503; mu= 15.2209+/- 0.031
mean_var=132.4603+/-28.313, 0's: 0 Z-trim(111.0): 192 B-trim: 59 in 1/54
Lambda= 0.111438
statistics sampled from 19169 (19433) to 19169 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.586), E-opt: 0.2 (0.228), width: 16
Scan time: 6.850
The best scores are: opt bits E(85289)
XP_016874611 (OMIM: 605269) PREDICTED: coronin-1C ( 474) 3208 528.1 2e-149
XP_016874612 (OMIM: 605269) PREDICTED: coronin-1C ( 474) 3208 528.1 2e-149
NP_055140 (OMIM: 605269) coronin-1C isoform b [Hom ( 474) 3208 528.1 2e-149
NP_001263400 (OMIM: 605269) coronin-1C isoform b [ ( 474) 3208 528.1 2e-149
NP_001098707 (OMIM: 605269) coronin-1C isoform a [ ( 527) 3208 528.2 2.2e-149
XP_016874610 (OMIM: 605269) PREDICTED: coronin-1C ( 527) 3208 528.2 2.2e-149
NP_001018080 (OMIM: 609849) coronin-1B [Homo sapie ( 489) 2474 410.1 6.9e-114
NP_065174 (OMIM: 609849) coronin-1B [Homo sapiens] ( 489) 2474 410.1 6.9e-114
XP_011544016 (OMIM: 605000,615401) PREDICTED: coro ( 461) 2155 358.8 1.8e-98
NP_001180262 (OMIM: 605000,615401) coronin-1A [Hom ( 461) 2155 358.8 1.8e-98
NP_009005 (OMIM: 605000,615401) coronin-1A [Homo s ( 461) 2155 358.8 1.8e-98
XP_016878374 (OMIM: 605000,615401) PREDICTED: coro ( 463) 2150 358.0 3.2e-98
XP_016878375 (OMIM: 605000,615401) PREDICTED: coro ( 463) 2150 358.0 3.2e-98
XP_011536427 (OMIM: 605269) PREDICTED: coronin-1C ( 286) 1764 295.7 1.1e-79
NP_001177385 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 1429 242.1 2.5e-63
NP_001310944 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 1429 242.1 2.5e-63
NP_001177386 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 1429 242.1 2.5e-63
NP_001310943 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 1429 242.1 2.5e-63
NP_006082 (OMIM: 605002) coronin-2B isoform 1 [Hom ( 480) 1429 242.1 2.5e-63
NP_438171 (OMIM: 602159) coronin-2A [Homo sapiens] ( 525) 1385 235.1 3.6e-61
XP_011517288 (OMIM: 602159) PREDICTED: coronin-2A ( 525) 1385 235.1 3.6e-61
NP_003380 (OMIM: 602159) coronin-2A [Homo sapiens] ( 525) 1385 235.1 3.6e-61
NP_078811 (OMIM: 611668) coronin-7 isoform 1 [Homo ( 925) 719 128.3 9.1e-29
NP_001188401 (OMIM: 611668) coronin-7 isoform 2 [H ( 907) 619 112.2 6.2e-24
NP_001188402 (OMIM: 611668) coronin-7 isoform 3 [H ( 840) 506 94.0 1.7e-18
NP_599027 (OMIM: 610091) WD repeat and SOCS box-co ( 275) 255 53.1 1.2e-06
NP_056441 (OMIM: 610091) WD repeat and SOCS box-co ( 421) 254 53.1 1.7e-06
XP_016879923 (OMIM: 610091) PREDICTED: WD repeat a ( 216) 193 43.0 0.00098
XP_005258020 (OMIM: 610091) PREDICTED: WD repeat a ( 216) 193 43.0 0.00098
NP_115737 (OMIM: 606929) THO complex subunit 3 [Ho ( 351) 194 43.4 0.0012
NP_004805 (OMIM: 607797) U5 small nuclear ribonucl ( 357) 191 42.9 0.0017
NP_001333155 (OMIM: 612167) WD repeat-containing p ( 620) 192 43.4 0.0022
NP_065890 (OMIM: 612167) WD repeat-containing prot ( 677) 192 43.4 0.0024
XP_005265403 (OMIM: 612167) PREDICTED: WD repeat-c ( 707) 192 43.4 0.0024
NP_001333157 (OMIM: 612167) WD repeat-containing p ( 607) 191 43.2 0.0024
XP_011532273 (OMIM: 612167) PREDICTED: WD repeat-c ( 637) 191 43.2 0.0025
NP_001309195 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 186 42.0 0.0025
NP_001309196 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 186 42.0 0.0025
NP_001231855 (OMIM: 607795,615922) U4/U6 small nuc ( 521) 186 42.3 0.0039
NP_004688 (OMIM: 607795,615922) U4/U6 small nuclea ( 522) 186 42.3 0.0039
XP_005262782 (OMIM: 609005) PREDICTED: WD repeat-c (1216) 184 42.4 0.0085
NP_001246 (OMIM: 603618) cell division cycle prote ( 499) 178 41.0 0.0091
>>XP_016874611 (OMIM: 605269) PREDICTED: coronin-1C isof (474 aa)
initn: 3208 init1: 3208 opt: 3208 Z-score: 2803.6 bits: 528.1 E(85289): 2e-149
Smith-Waterman score: 3208; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474)
10 20 30 40 50 60
pF1KB5 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 EPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 SERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 YVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 LYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANKKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANKKC
370 380 390 400 410 420
430 440 450 460 470
pF1KB5 DLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA
430 440 450 460 470
>>XP_016874612 (OMIM: 605269) PREDICTED: coronin-1C isof (474 aa)
initn: 3208 init1: 3208 opt: 3208 Z-score: 2803.6 bits: 528.1 E(85289): 2e-149
Smith-Waterman score: 3208; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474)
10 20 30 40 50 60
pF1KB5 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 EPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 SERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 YVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 LYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANKKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANKKC
370 380 390 400 410 420
430 440 450 460 470
pF1KB5 DLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA
430 440 450 460 470
>>NP_055140 (OMIM: 605269) coronin-1C isoform b [Homo sa (474 aa)
initn: 3208 init1: 3208 opt: 3208 Z-score: 2803.6 bits: 528.1 E(85289): 2e-149
Smith-Waterman score: 3208; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474)
10 20 30 40 50 60
pF1KB5 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 EPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 SERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 YVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 LYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANKKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANKKC
370 380 390 400 410 420
430 440 450 460 470
pF1KB5 DLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA
430 440 450 460 470
>>NP_001263400 (OMIM: 605269) coronin-1C isoform b [Homo (474 aa)
initn: 3208 init1: 3208 opt: 3208 Z-score: 2803.6 bits: 528.1 E(85289): 2e-149
Smith-Waterman score: 3208; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474)
10 20 30 40 50 60
pF1KB5 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 EPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 SERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 YVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 LYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANKKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANKKC
370 380 390 400 410 420
430 440 450 460 470
pF1KB5 DLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA
430 440 450 460 470
>>NP_001098707 (OMIM: 605269) coronin-1C isoform a [Homo (527 aa)
initn: 3208 init1: 3208 opt: 3208 Z-score: 2803.0 bits: 528.2 E(85289): 2.2e-149
Smith-Waterman score: 3208; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:54-527)
10 20 30
pF1KB5 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVS
::::::::::::::::::::::::::::::
NP_001 IACQGSLTSARLHAPSIGERPLSHMRWKDTMRRVVRQSKFRHVFGQAVKNDQCYDDIRVS
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB5 RVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCP
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB5 HNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAG
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB5 CDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKDKKVRVIDPRKQEIVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKDKKVRVIDPRKQEIVA
210 220 230 240 250 260
220 230 240 250 260 270
pF1KB5 EKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMQEPIALHEMDTSNGVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMQEPIALHEMDTSNGVLL
270 280 290 300 310 320
280 290 300 310 320 330
pF1KB5 PFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKC
330 340 350 360 370 380
340 350 360 370 380 390
pF1KB5 EIARFFKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNADPILISL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIARFFKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNADPILISL
390 400 410 420 430 440
400 410 420 430 440 450
pF1KB5 KHGYIPGKNRDLKVVKKNILDSKPTANKKCDLISIPKKTTDTASVQNEAKLDEILKEIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHGYIPGKNRDLKVVKKNILDSKPTANKKCDLISIPKKTTDTASVQNEAKLDEILKEIKS
450 460 470 480 490 500
460 470
pF1KB5 IKDTICNQDERISKLEQQMAKIAA
::::::::::::::::::::::::
NP_001 IKDTICNQDERISKLEQQMAKIAA
510 520
>>XP_016874610 (OMIM: 605269) PREDICTED: coronin-1C isof (527 aa)
initn: 3208 init1: 3208 opt: 3208 Z-score: 2803.0 bits: 528.2 E(85289): 2.2e-149
Smith-Waterman score: 3208; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:54-527)
10 20 30
pF1KB5 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVS
::::::::::::::::::::::::::::::
XP_016 IACQGSLTSARLHAPSIGERPLSHMRWKDTMRRVVRQSKFRHVFGQAVKNDQCYDDIRVS
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB5 RVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCP
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB5 HNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAG
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB5 CDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKDKKVRVIDPRKQEIVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKDKKVRVIDPRKQEIVA
210 220 230 240 250 260
220 230 240 250 260 270
pF1KB5 EKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMQEPIALHEMDTSNGVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMQEPIALHEMDTSNGVLL
270 280 290 300 310 320
280 290 300 310 320 330
pF1KB5 PFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKC
330 340 350 360 370 380
340 350 360 370 380 390
pF1KB5 EIARFFKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNADPILISL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIARFFKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNADPILISL
390 400 410 420 430 440
400 410 420 430 440 450
pF1KB5 KHGYIPGKNRDLKVVKKNILDSKPTANKKCDLISIPKKTTDTASVQNEAKLDEILKEIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHGYIPGKNRDLKVVKKNILDSKPTANKKCDLISIPKKTTDTASVQNEAKLDEILKEIKS
450 460 470 480 490 500
460 470
pF1KB5 IKDTICNQDERISKLEQQMAKIAA
::::::::::::::::::::::::
XP_016 IKDTICNQDERISKLEQQMAKIAA
510 520
>>NP_001018080 (OMIM: 609849) coronin-1B [Homo sapiens] (489 aa)
initn: 2445 init1: 2445 opt: 2474 Z-score: 2165.7 bits: 410.1 E(85289): 6.9e-114
Smith-Waterman score: 2538; 73.2% identity (91.5% similar) in 481 aa overlap (2-472:4-484)
10 20 30 40 50
pF1KB5 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAF
:.::::::::::::: :::::::.:::::::::::.::::::.:.:.:.::::::::
NP_001 MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 LVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLS
::::: :::::::.:::::::::::::::::::::.::::::::::::::::::::::
NP_001 LVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 LTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIY
::::::.::::.:::::.:::::::::::::::::...::::::.: : ::..: :.::
NP_001 LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIY
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 NVSWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFS
:::::.::::.:.: :::.::.::::. .:::.::::::::::::::::::.:::::::
NP_001 NVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 RMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDE
::::::::::.:.:..::.::.:.:.:::.::::::::::..:.::::::::::::::.:
NP_001 RMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 SPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQ
::.:.::::.::::::::: ::::::.:.:::::::.::::::::::.:::::::::::
NP_001 PPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQ
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 DDLYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNIL-DSKPTAN
::::::::::::::::::: :..::::::::...:.:.:.::::. ..:.: ::.:.
NP_001 DDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMA
370 380 390 400 410 420
420 430 440 450 460
pF1KB5 KKCDLISIPKKTTDTASVQ--------NEA-KLDEILKEIKSIKDTICNQDERISKLEQQ
. .. : .:: .:.. .:: ::.:...:..... . .: .:: .::.:
NP_001 PGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQ
430 440 450 460 470 480
470
pF1KB5 MAKIAA
....
NP_001 LGRMENGDA
>>NP_065174 (OMIM: 609849) coronin-1B [Homo sapiens] (489 aa)
initn: 2445 init1: 2445 opt: 2474 Z-score: 2165.7 bits: 410.1 E(85289): 6.9e-114
Smith-Waterman score: 2538; 73.2% identity (91.5% similar) in 481 aa overlap (2-472:4-484)
10 20 30 40 50
pF1KB5 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAF
:.::::::::::::: :::::::.:::::::::::.::::::.:.:.:.::::::::
NP_065 MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 LVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLS
::::: :::::::.:::::::::::::::::::::.::::::::::::::::::::::
NP_065 LVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 LTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIY
::::::.::::.:::::.:::::::::::::::::...::::::.: : ::..: :.::
NP_065 LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIY
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 NVSWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFS
:::::.::::.:.: :::.::.::::. .:::.::::::::::::::::::.:::::::
NP_065 NVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 RMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDE
::::::::::.:.:..::.::.:.:.:::.::::::::::..:.::::::::::::::.:
NP_065 RMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 SPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQ
::.:.::::.::::::::: ::::::.:.:::::::.::::::::::.:::::::::::
NP_065 PPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQ
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 DDLYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNIL-DSKPTAN
::::::::::::::::::: :..::::::::...:.:.:.::::. ..:.: ::.:.
NP_065 DDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMA
370 380 390 400 410 420
420 430 440 450 460
pF1KB5 KKCDLISIPKKTTDTASVQ--------NEA-KLDEILKEIKSIKDTICNQDERISKLEQQ
. .. : .:: .:.. .:: ::.:...:..... . .: .:: .::.:
NP_065 PGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQ
430 440 450 460 470 480
470
pF1KB5 MAKIAA
....
NP_065 LGRMENGDA
>>XP_011544016 (OMIM: 605000,615401) PREDICTED: coronin- (461 aa)
initn: 2122 init1: 1198 opt: 2155 Z-score: 1888.8 bits: 358.8 E(85289): 1.8e-98
Smith-Waterman score: 2170; 65.3% identity (88.0% similar) in 467 aa overlap (2-467:3-456)
10 20 30 40 50
pF1KB5 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFL
:.:::.::::::::: .: ::::.:.:::..::::.::::::.:::.: :::::::::
XP_011 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 VLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSL
:::: ::::.::. :::::::.::::: ::::::.::::::::::::::.::..:: : :
XP_011 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 TEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLD-DMHSDMIY
:::: ::::.::::::::: ::.::::::::::.:..:.:::: :...: ..: : ::
XP_011 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 NVSWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFS
.:.:.:.:.::::. .::.::.:.::: .::::.. :::.::.::.:...:...:::::
XP_011 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 RMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDE
::::::.:::. :...::..:.:.:::.::::::.::::.:.::::::::::::::::.:
XP_011 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 SPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQ
.:..:::. ::::: ::::::::::::.:::::::::.:::::.:::: :::::::::::
XP_011 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 DDLYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANK
.:::: ::::. :: ::::. :..: :.::::: ::.: :.:.:.: . :: :. .
XP_011 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LD---TGRR
370 380 390 400 410
420 430 440 450 460 470
pF1KB5 KCDLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA
. . :. .. : : . ..:.: :..... :. . ..:...::.
XP_011 R----AAPE-ASGTPSSDAVSRLEE---EMRKLQATVQELQKRLDRLEETVQAK
420 430 440 450 460
>>NP_001180262 (OMIM: 605000,615401) coronin-1A [Homo sa (461 aa)
initn: 2122 init1: 1198 opt: 2155 Z-score: 1888.8 bits: 358.8 E(85289): 1.8e-98
Smith-Waterman score: 2170; 65.3% identity (88.0% similar) in 467 aa overlap (2-467:3-456)
10 20 30 40 50
pF1KB5 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFL
:.:::.::::::::: .: ::::.:.:::..::::.::::::.:::.: :::::::::
NP_001 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 VLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSL
:::: ::::.::. :::::::.::::: ::::::.::::::::::::::.::..:: : :
NP_001 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 TEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLD-DMHSDMIY
:::: ::::.::::::::: ::.::::::::::.:..:.:::: :...: ..: : ::
NP_001 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 NVSWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFS
.:.:.:.:.::::. .::.::.:.::: .::::.. :::.::.::.:...:...:::::
NP_001 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 RMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDE
::::::.:::. :...::..:.:.:::.::::::.::::.:.::::::::::::::::.:
NP_001 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 SPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQ
.:..:::. ::::: ::::::::::::.:::::::::.:::::.:::: :::::::::::
NP_001 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 DDLYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANK
.:::: ::::. :: ::::. :..: :.::::: ::.: :.:.:.: . :: :. .
NP_001 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LD---TGRR
370 380 390 400 410
420 430 440 450 460 470
pF1KB5 KCDLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA
. . :. .. : : . ..:.: :..... :. . ..:...::.
NP_001 R----AAPE-ASGTPSSDAVSRLEE---EMRKLQATVQELQKRLDRLEETVQAK
420 430 440 450 460
474 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 13:09:05 2016 done: Sat Nov 5 13:09:06 2016
Total Scan time: 6.850 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]