Result of FASTA (omim) for
pFN21AB5289
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5289, 418 aa
1>>>pF1KB5289 418 - 418 aa - 418 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5066+/-0.000346; mu= 16.9489+/- 0.022
mean_var=71.6530+/-14.510, 0's: 0 Z-trim(115.1): 126 B-trim: 800 in 1/58
Lambda= 0.151515
statistics sampled from 25181 (25326) to 25181 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.672), E-opt: 0.2 (0.297), width: 16
Scan time: 9.610
The best scores are: opt bits E(85289)
NP_002606 (OMIM: 172860,613982) pigment epithelium ( 418) 2703 599.9 3.9e-171
NP_001316832 (OMIM: 172860,613982) pigment epithel ( 418) 2703 599.9 3.9e-171
NP_001316833 (OMIM: 172860,613982) pigment epithel ( 231) 1509 338.7 8.8e-93
NP_001316834 (OMIM: 172860,613982) pigment epithel ( 231) 1509 338.7 8.8e-93
NP_000925 (OMIM: 262850,613168) alpha-2-antiplasmi ( 491) 607 141.8 3.7e-33
NP_001159392 (OMIM: 262850,613168) alpha-2-antipla ( 491) 607 141.8 3.7e-33
XP_016880254 (OMIM: 262850,613168) PREDICTED: alph ( 495) 607 141.8 3.8e-33
XP_005256758 (OMIM: 262850,613168) PREDICTED: alph ( 507) 607 141.8 3.8e-33
XP_016876859 (OMIM: 107400,606963,613490) PREDICTE ( 418) 567 133.0 1.4e-30
NP_001121177 (OMIM: 107400,606963,613490) alpha-1- ( 418) 567 133.0 1.4e-30
NP_001121172 (OMIM: 107400,606963,613490) alpha-1- ( 418) 567 133.0 1.4e-30
NP_001121175 (OMIM: 107400,606963,613490) alpha-1- ( 418) 567 133.0 1.4e-30
NP_001121176 (OMIM: 107400,606963,613490) alpha-1- ( 418) 567 133.0 1.4e-30
NP_001121179 (OMIM: 107400,606963,613490) alpha-1- ( 418) 567 133.0 1.4e-30
NP_001002235 (OMIM: 107400,606963,613490) alpha-1- ( 418) 567 133.0 1.4e-30
NP_001121178 (OMIM: 107400,606963,613490) alpha-1- ( 418) 567 133.0 1.4e-30
NP_000286 (OMIM: 107400,606963,613490) alpha-1-ant ( 418) 567 133.0 1.4e-30
NP_001002236 (OMIM: 107400,606963,613490) alpha-1- ( 418) 567 133.0 1.4e-30
NP_001121173 (OMIM: 107400,606963,613490) alpha-1- ( 418) 567 133.0 1.4e-30
NP_001121174 (OMIM: 107400,606963,613490) alpha-1- ( 418) 567 133.0 1.4e-30
NP_006211 (OMIM: 107410) putative alpha-1-antitryp ( 421) 536 126.2 1.5e-28
NP_001747 (OMIM: 122500,611489) corticosteroid-bin ( 405) 534 125.7 2e-28
NP_001076 (OMIM: 107280) alpha-1-antichymotrypsin ( 423) 527 124.2 6e-28
XP_005267790 (OMIM: 605271) PREDICTED: protein Z-d ( 444) 525 123.8 8.5e-28
NP_001094077 (OMIM: 605271) protein Z-dependent pr ( 444) 525 123.8 8.5e-28
NP_057270 (OMIM: 605271) protein Z-dependent prote ( 444) 525 123.8 8.5e-28
XP_016876842 (OMIM: 605271) PREDICTED: protein Z-d ( 484) 525 123.8 9.2e-28
NP_000053 (OMIM: 106100,120790,606860) plasma prot ( 500) 522 123.2 1.5e-27
NP_001027466 (OMIM: 106100,120790,606860) plasma p ( 500) 522 123.2 1.5e-27
NP_006206 (OMIM: 147935) kallistatin isoform 2 pre ( 427) 521 122.9 1.5e-27
NP_001275962 (OMIM: 147935) kallistatin isoform 2 ( 427) 521 122.9 1.5e-27
NP_001275961 (OMIM: 147935) kallistatin isoform 1 ( 464) 521 122.9 1.6e-27
XP_011535016 (OMIM: 615677) PREDICTED: serpin A9 i ( 417) 516 121.8 3.2e-27
XP_011535017 (OMIM: 615677) PREDICTED: serpin A9 i ( 417) 516 121.8 3.2e-27
NP_783866 (OMIM: 615677) serpin A9 isoform A [Homo ( 435) 516 121.8 3.3e-27
NP_000615 (OMIM: 601841) plasma serine protease in ( 406) 500 118.3 3.5e-26
NP_001159393 (OMIM: 262850,613168) alpha-2-antipla ( 427) 500 118.3 3.6e-26
NP_000345 (OMIM: 300932,314200) thyroxine-binding ( 415) 492 116.6 1.2e-25
NP_001271204 (OMIM: 615677) serpin A9 isoform C [H ( 399) 467 111.1 5.1e-24
NP_001193943 (OMIM: 600943,610504,613848) serpin H ( 418) 448 107.0 9.5e-23
XP_011543629 (OMIM: 600943,610504,613848) PREDICTE ( 418) 448 107.0 9.5e-23
NP_001226 (OMIM: 600943,610504,613848) serpin H1 p ( 418) 448 107.0 9.5e-23
NP_006208 (OMIM: 605587) serpin I2 isoform 2 precu ( 405) 419 100.6 7.5e-21
NP_001012303 (OMIM: 605587) serpin I2 isoform 1 pr ( 415) 419 100.6 7.6e-21
XP_005245255 (OMIM: 107300,613118) PREDICTED: anti ( 416) 418 100.4 8.9e-21
NP_000479 (OMIM: 107300,613118) antithrombin-III p ( 464) 418 100.4 9.7e-21
XP_006724746 (OMIM: 300932,314200) PREDICTED: thyr ( 425) 415 99.7 1.4e-20
XP_005262237 (OMIM: 300932,314200) PREDICTED: thyr ( 371) 411 98.8 2.3e-20
XP_011535018 (OMIM: 615677) PREDICTED: serpin A9 i ( 337) 403 97.1 7.2e-20
XP_011535019 (OMIM: 615677) PREDICTED: serpin A9 i ( 337) 403 97.1 7.2e-20
>>NP_002606 (OMIM: 172860,613982) pigment epithelium-der (418 aa)
initn: 2703 init1: 2703 opt: 2703 Z-score: 3193.4 bits: 599.9 E(85289): 3.9e-171
Smith-Waterman score: 2703; 99.8% identity (99.8% similar) in 418 aa overlap (1-418:1-418)
10 20 30 40 50 60
pF1KB5 MQALVLLLCIGALLGHSSCQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MQALVLLLCIGALLGHSSCQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 FGYDLYRVRSSMSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPDIHG
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPDIHG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 TYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGNPRLDLQEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGNPRLDLQEI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 VPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGKPIKLTQVEHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGKPIKLTQVEHRA
310 320 330 340 350 360
370 380 390 400 410
pF1KB5 GFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDPRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDPRGP
370 380 390 400 410
>>NP_001316832 (OMIM: 172860,613982) pigment epithelium- (418 aa)
initn: 2703 init1: 2703 opt: 2703 Z-score: 3193.4 bits: 599.9 E(85289): 3.9e-171
Smith-Waterman score: 2703; 99.8% identity (99.8% similar) in 418 aa overlap (1-418:1-418)
10 20 30 40 50 60
pF1KB5 MQALVLLLCIGALLGHSSCQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQALVLLLCIGALLGHSSCQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 FGYDLYRVRSSMSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPDIHG
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPDIHG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 TYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGNPRLDLQEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGNPRLDLQEI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 NNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 VPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGKPIKLTQVEHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGKPIKLTQVEHRA
310 320 330 340 350 360
370 380 390 400 410
pF1KB5 GFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDPRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDPRGP
370 380 390 400 410
>>NP_001316833 (OMIM: 172860,613982) pigment epithelium- (231 aa)
initn: 1509 init1: 1509 opt: 1509 Z-score: 1786.7 bits: 338.7 E(85289): 8.8e-93
Smith-Waterman score: 1509; 100.0% identity (100.0% similar) in 231 aa overlap (188-418:1-231)
160 170 180 190 200 210
pF1KB5 LEKSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQW
::::::::::::::::::::::::::::::
NP_001 MKGKLARSTKEIPDEISILLLGVAHFKGQW
10 20 30
220 230 240 250 260 270
pF1KB5 VTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFF
40 50 60 70 80 90
280 290 300 310 320 330
pF1KB5 LPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSL
100 110 120 130 140 150
340 350 360 370 380 390
pF1KB5 FDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFV
160 170 180 190 200 210
400 410
pF1KB5 LRDTDTGALLFIGKILDPRGP
:::::::::::::::::::::
NP_001 LRDTDTGALLFIGKILDPRGP
220 230
>>NP_001316834 (OMIM: 172860,613982) pigment epithelium- (231 aa)
initn: 1509 init1: 1509 opt: 1509 Z-score: 1786.7 bits: 338.7 E(85289): 8.8e-93
Smith-Waterman score: 1509; 100.0% identity (100.0% similar) in 231 aa overlap (188-418:1-231)
160 170 180 190 200 210
pF1KB5 LEKSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQW
::::::::::::::::::::::::::::::
NP_001 MKGKLARSTKEIPDEISILLLGVAHFKGQW
10 20 30
220 230 240 250 260 270
pF1KB5 VTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFF
40 50 60 70 80 90
280 290 300 310 320 330
pF1KB5 LPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSL
100 110 120 130 140 150
340 350 360 370 380 390
pF1KB5 FDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFV
160 170 180 190 200 210
400 410
pF1KB5 LRDTDTGALLFIGKILDPRGP
:::::::::::::::::::::
NP_001 LRDTDTGALLFIGKILDPRGP
220 230
>>NP_000925 (OMIM: 262850,613168) alpha-2-antiplasmin is (491 aa)
initn: 599 init1: 326 opt: 607 Z-score: 716.2 bits: 141.8 E(85289): 3.7e-33
Smith-Waterman score: 607; 29.0% identity (63.5% similar) in 414 aa overlap (10-415:31-436)
10 20 30
pF1KB5 MQALVLLLCIGALLGHSSCQNPASPP---EEGSPDPDST
.: : . :. .:: . :. .: .
NP_000 MALLWGLLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQEPGGQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 GAL-----VEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSMSPTTNVLLSPLSVATALSA
:: : .:: . ...:: :. : ::. . .. : :..::::::: :::
NP_000 TALKSPPGVCSRDPTPE-QTHRLARAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSH
70 80 90 100 110
100 110 120 130 140 150
pF1KB5 LSLGAEQRTESIIHRALYYDLISSPDIHGTYKELLDTVTAPQKNLKSASRIVFEKKLRIK
:.:::...: . ....:. :.: . ..: . . .: .. :.:. ..: . ::
NP_000 LALGAQNHTLQRLQQVLHAG--SGPCLPHLLSRLCQDL-GPGA-FRLAARMYLQKGFPIK
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB5 SSFVAPLEKSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVA
.:. :. .:..: :::. . :: .::.::. .::. . . .:.. .:::..
NP_000 EDFLEQSEQLFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAI
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB5 HFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGS
::.: : .::: :. ..:.:::. :: : ::. ::. : . ..:..:. ..
NP_000 HFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNN
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 MSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQE
::.. ..: . :.. . .:. . .: . ... : ::: :... ... .:..
NP_000 MSFVVLVPTHFEWNVSQVLANLSWDTLHPPLVWERPTKVRL--PKLYLKHQMDLVATLSQ
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB5 MKLQSLFDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLN
. :: ::..::. :. . . .. :.:.. .: .: :. .. . .. ..... .. .:
NP_000 LGLQELFQAPDLRGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLS-SFSVN
360 370 380 390 400 410
400 410
pF1KB5 QPFIFVLRDTDTGALLFIGKILDPRGP
.::.: . . :: ::.:.. .:
NP_000 RPFLFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGP
420 430 440 450 460 470
>>NP_001159392 (OMIM: 262850,613168) alpha-2-antiplasmin (491 aa)
initn: 599 init1: 326 opt: 607 Z-score: 716.2 bits: 141.8 E(85289): 3.7e-33
Smith-Waterman score: 607; 29.0% identity (63.5% similar) in 414 aa overlap (10-415:31-436)
10 20 30
pF1KB5 MQALVLLLCIGALLGHSSCQNPASPP---EEGSPDPDST
.: : . :. .:: . :. .: .
NP_001 MALLWGLLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQEPGGQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 GAL-----VEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSMSPTTNVLLSPLSVATALSA
:: : .:: . ...:: :. : ::. . .. : :..::::::: :::
NP_001 TALKSPPGVCSRDPTPE-QTHRLARAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSH
70 80 90 100 110
100 110 120 130 140 150
pF1KB5 LSLGAEQRTESIIHRALYYDLISSPDIHGTYKELLDTVTAPQKNLKSASRIVFEKKLRIK
:.:::...: . ....:. :.: . ..: . . .: .. :.:. ..: . ::
NP_001 LALGAQNHTLQRLQQVLHAG--SGPCLPHLLSRLCQDL-GPGA-FRLAARMYLQKGFPIK
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB5 SSFVAPLEKSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVA
.:. :. .:..: :::. . :: .::.::. .::. . . .:.. .:::..
NP_001 EDFLEQSEQLFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAI
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB5 HFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGS
::.: : .::: :. ..:.:::. :: : ::. ::. : . ..:..:. ..
NP_001 HFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNN
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 MSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQE
::.. ..: . :.. . .:. . .: . ... : ::: :... ... .:..
NP_001 MSFVVLVPTHFEWNVSQVLANLSWDTLHPPLVWERPTKVRL--PKLYLKHQMDLVATLSQ
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB5 MKLQSLFDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLN
. :: ::..::. :. . . .. :.:.. .: .: :. .. . .. ..... .. .:
NP_001 LGLQELFQAPDLRGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLS-SFSVN
360 370 380 390 400 410
400 410
pF1KB5 QPFIFVLRDTDTGALLFIGKILDPRGP
.::.: . . :: ::.:.. .:
NP_001 RPFLFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGP
420 430 440 450 460 470
>>XP_016880254 (OMIM: 262850,613168) PREDICTED: alpha-2- (495 aa)
initn: 599 init1: 326 opt: 607 Z-score: 716.2 bits: 141.8 E(85289): 3.8e-33
Smith-Waterman score: 607; 29.0% identity (63.5% similar) in 414 aa overlap (10-415:35-440)
10 20 30
pF1KB5 MQALVLLLCIGALLGHSSCQNPASPP---EEGSPDPDST
.: : . :. .:: . :. .: .
XP_016 MALLWGLLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQEPGGQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 GAL-----VEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSMSPTTNVLLSPLSVATALSA
:: : .:: . ...:: :. : ::. . .. : :..::::::: :::
XP_016 TALKSPPGVCSRDPTPE-QTHRLARAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSH
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB5 LSLGAEQRTESIIHRALYYDLISSPDIHGTYKELLDTVTAPQKNLKSASRIVFEKKLRIK
:.:::...: . ....:. :.: . ..: . . .: .. :.:. ..: . ::
XP_016 LALGAQNHTLQRLQQVLHAG--SGPCLPHLLSRLCQDL-GPGA-FRLAARMYLQKGFPIK
130 140 150 160 170
160 170 180 190 200 210
pF1KB5 SSFVAPLEKSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVA
.:. :. .:..: :::. . :: .::.::. .::. . . .:.. .:::..
XP_016 EDFLEQSEQLFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAI
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB5 HFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGS
::.: : .::: :. ..:.:::. :: : ::. ::. : . ..:..:. ..
XP_016 HFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNN
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 MSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQE
::.. ..: . :.. . .:. . .: . ... : ::: :... ... .:..
XP_016 MSFVVLVPTHFEWNVSQVLANLSWDTLHPPLVWERPTKVRL--PKLYLKHQMDLVATLSQ
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB5 MKLQSLFDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLN
. :: ::..::. :. . . .. :.:.. .: .: :. .. . .. ..... .. .:
XP_016 LGLQELFQAPDLRGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLS-SFSVN
360 370 380 390 400 410
400 410
pF1KB5 QPFIFVLRDTDTGALLFIGKILDPRGP
.::.: . . :: ::.:.. .:
XP_016 RPFLFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGP
420 430 440 450 460 470
>>XP_005256758 (OMIM: 262850,613168) PREDICTED: alpha-2- (507 aa)
initn: 599 init1: 326 opt: 607 Z-score: 716.0 bits: 141.8 E(85289): 3.8e-33
Smith-Waterman score: 607; 29.0% identity (63.5% similar) in 414 aa overlap (10-415:47-452)
10 20 30
pF1KB5 MQALVLLLCIGALLGHSSCQNPASPP---EEGSPDPDST
.: : . :. .:: . :. .: .
XP_005 MALLWGLLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQEPGGQ
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB5 GAL-----VEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSMSPTTNVLLSPLSVATALSA
:: : .:: . ...:: :. : ::. . .. : :..::::::: :::
XP_005 TALKSPPGVCSRDPTPE-QTHRLARAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSH
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB5 LSLGAEQRTESIIHRALYYDLISSPDIHGTYKELLDTVTAPQKNLKSASRIVFEKKLRIK
:.:::...: . ....:. :.: . ..: . . .: .. :.:. ..: . ::
XP_005 LALGAQNHTLQRLQQVLHAG--SGPCLPHLLSRLCQDL-GPGA-FRLAARMYLQKGFPIK
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB5 SSFVAPLEKSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVA
.:. :. .:..: :::. . :: .::.::. .::. . . .:.. .:::..
XP_005 EDFLEQSEQLFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAI
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB5 HFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGS
::.: : .::: :. ..:.:::. :: : ::. ::. : . ..:..:. ..
XP_005 HFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNN
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB5 MSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQE
::.. ..: . :.. . .:. . .: . ... : ::: :... ... .:..
XP_005 MSFVVLVPTHFEWNVSQVLANLSWDTLHPPLVWERPTKVRL--PKLYLKHQMDLVATLSQ
320 330 340 350 360
340 350 360 370 380 390
pF1KB5 MKLQSLFDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLN
. :: ::..::. :. . . .. :.:.. .: .: :. .. . .. ..... .. .:
XP_005 LGLQELFQAPDLRGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLS-SFSVN
370 380 390 400 410 420
400 410
pF1KB5 QPFIFVLRDTDTGALLFIGKILDPRGP
.::.: . . :: ::.:.. .:
XP_005 RPFLFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGP
430 440 450 460 470 480
>>XP_016876859 (OMIM: 107400,606963,613490) PREDICTED: a (418 aa)
initn: 434 init1: 165 opt: 567 Z-score: 670.0 bits: 133.0 E(85289): 1.4e-30
Smith-Waterman score: 567; 28.1% identity (63.1% similar) in 417 aa overlap (13-415:11-415)
10 20 30 40 50
pF1KB5 MQALVLLLCIGALLGHSSCQNPASPPEEGSPDP-DSTGALVEEED-PFFKVPVNKLAAAV
::. : :.: :. . : ..: . ...: : : ::.. .
XP_016 MPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTF----NKITPNL
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 SNFGYDLYRVRSSMSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPD-
..:...::: . .: .::...::.:.:::.. ::::.. :.. : ..: ..: :.
XP_016 AEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 -IHGTYKELLDTVTAP--QKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLT-GNP
:: ..::: :.. : : .: ... . . . :.. ..:. ..: : .. ... :.
XP_016 QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 RLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYL
. ..::..:. .::.. .::. . . :.. :::.: :. . : :::..
XP_016 EEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHV
180 190 200 210 220 230
240 250 260 270 280
pF1KB5 DEERTVRVPMMSDPKAVLRYGLDSDLSCK-----IAQLPLTGSMSIIFFLPLKVTQNLTL
:. ::.::::. : :. . :: . . :. . ::::: . .:
XP_016 DQVTTVKVPMMK------RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQH
240 250 260 270 280
290 300 310 320 330 340
pF1KB5 IEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLF-DSPDFSKIT
.:. :: ..: . .. .: : .:::... .. . : .. . ..: .. :.: .:
XP_016 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVT
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB5 GK-PIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGAL
. :.::... :.: . .: :. .. . :. ...: . ..:.::.:.. . .: .
XP_016 EEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSP
350 360 370 380 390 400
410
pF1KB5 LFIGKILDPRGP
::.::...:
XP_016 LFMGKVVNPTQK
410
>>NP_001121177 (OMIM: 107400,606963,613490) alpha-1-anti (418 aa)
initn: 434 init1: 165 opt: 567 Z-score: 670.0 bits: 133.0 E(85289): 1.4e-30
Smith-Waterman score: 567; 28.1% identity (63.1% similar) in 417 aa overlap (13-415:11-415)
10 20 30 40 50
pF1KB5 MQALVLLLCIGALLGHSSCQNPASPPEEGSPDP-DSTGALVEEED-PFFKVPVNKLAAAV
::. : :.: :. . : ..: . ...: : : ::.. .
NP_001 MPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTF----NKITPNL
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 SNFGYDLYRVRSSMSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPD-
..:...::: . .: .::...::.:.:::.. ::::.. :.. : ..: ..: :.
NP_001 AEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 -IHGTYKELLDTVTAP--QKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLT-GNP
:: ..::: :.. : : .: ... . . . :.. ..:. ..: : .. ... :.
NP_001 QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 RLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYL
. ..::..:. .::.. .::. . . :.. :::.: :. . : :::..
NP_001 EEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHV
180 190 200 210 220 230
240 250 260 270 280
pF1KB5 DEERTVRVPMMSDPKAVLRYGLDSDLSCK-----IAQLPLTGSMSIIFFLPLKVTQNLTL
:. ::.::::. : :. . :: . . :. . ::::: . .:
NP_001 DQVTTVKVPMMK------RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE--GKLQH
240 250 260 270 280
290 300 310 320 330 340
pF1KB5 IEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLF-DSPDFSKIT
.:. :: ..: . .. .: : .:::... .. . : .. . ..: .. :.: .:
NP_001 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVT
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB5 GK-PIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGAL
. :.::... :.: . .: :. .. . :. ...: . ..:.::.:.. . .: .
NP_001 EEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSP
350 360 370 380 390 400
410
pF1KB5 LFIGKILDPRGP
::.::...:
NP_001 LFMGKVVNPTQK
410
418 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 12:24:42 2016 done: Sat Nov 5 12:24:43 2016
Total Scan time: 9.610 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]