Result of FASTA (omim) for
pFN21AB0405
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0405, 465 aa
1>>>pF1KB0405 465 - 465 aa - 465 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2814+/-0.00032; mu= 14.3742+/- 0.020
mean_var=119.2606+/-23.741, 0's: 0 Z-trim(119.4): 412 B-trim: 53 in 1/54
Lambda= 0.117443
statistics sampled from 32883 (33306) to 32883 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.741), E-opt: 0.2 (0.391), width: 16
Scan time: 9.700
The best scores are: opt bits E(85289)
NP_002823 (OMIM: 176889) tyrosine-protein phosphat ( 465) 3242 560.2 4.1e-159
XP_016857425 (OMIM: 176889) PREDICTED: tyrosine-pr ( 464) 3224 557.2 3.4e-158
XP_011508121 (OMIM: 176889) PREDICTED: tyrosine-pr ( 511) 3036 525.4 1.4e-148
XP_016857424 (OMIM: 176889) PREDICTED: tyrosine-pr ( 510) 3018 522.3 1.2e-147
NP_542155 (OMIM: 176889) tyrosine-protein phosphat ( 399) 2599 451.2 2.3e-126
NP_001186726 (OMIM: 176889) tyrosine-protein phosp ( 434) 2588 449.4 8.9e-126
XP_016857426 (OMIM: 176889) PREDICTED: tyrosine-pr ( 359) 2451 426.1 7.5e-119
XP_011508125 (OMIM: 176889) PREDICTED: tyrosine-pr ( 311) 2141 373.5 4.4e-103
XP_011508122 (OMIM: 176889) PREDICTED: tyrosine-pr ( 400) 2130 371.8 1.9e-102
XP_011508123 (OMIM: 176889) PREDICTED: tyrosine-pr ( 354) 1887 330.6 4.4e-90
XP_011508124 (OMIM: 176889) PREDICTED: tyrosine-pr ( 354) 1887 330.6 4.4e-90
NP_570897 (OMIM: 602853) receptor-type tyrosine-pr ( 412) 1293 230.0 9.7e-60
NP_001193945 (OMIM: 602853) receptor-type tyrosine ( 451) 1293 230.0 1e-59
NP_001193944 (OMIM: 602853) receptor-type tyrosine ( 545) 1293 230.1 1.2e-59
XP_011536917 (OMIM: 602853) PREDICTED: receptor-ty ( 649) 1293 230.1 1.4e-59
NP_002840 (OMIM: 602853) receptor-type tyrosine-pr ( 657) 1293 230.1 1.4e-59
NP_001265168 (OMIM: 176879) tyrosine-protein phosp ( 509) 1134 203.1 1.5e-51
NP_001035059 (OMIM: 176879) tyrosine-protein phosp ( 533) 1134 203.1 1.5e-51
NP_001265165 (OMIM: 176879) tyrosine-protein phosp ( 533) 1134 203.1 1.5e-51
NP_001265167 (OMIM: 176879) tyrosine-protein phosp ( 541) 1134 203.1 1.5e-51
NP_008837 (OMIM: 176879) tyrosine-protein phosphat ( 565) 1134 203.2 1.6e-51
NP_116170 (OMIM: 176879) tyrosine-protein phosphat ( 565) 1134 203.2 1.6e-51
XP_011508126 (OMIM: 176889) PREDICTED: tyrosine-pr ( 235) 1104 197.7 2.8e-50
XP_011518713 (OMIM: 176879) PREDICTED: tyrosine-pr ( 553) 1001 180.6 9.4e-45
XP_016873929 (OMIM: 176879) PREDICTED: tyrosine-pr ( 527) 658 122.5 2.8e-27
NP_109595 (OMIM: 600579,614196) receptor-type tyro ( 377) 653 121.5 4e-27
NP_109593 (OMIM: 600579,614196) receptor-type tyro ( 377) 653 121.5 4e-27
NP_109596 (OMIM: 600579,614196) receptor-type tyro ( 405) 653 121.5 4.2e-27
NP_109594 (OMIM: 600579,614196) receptor-type tyro ( 405) 653 121.5 4.2e-27
XP_016875213 (OMIM: 176882) PREDICTED: receptor-ty (1446) 657 122.7 6.7e-27
NP_001193900 (OMIM: 176882) receptor-type tyrosine (1907) 657 122.8 8.2e-27
NP_001193901 (OMIM: 176882) receptor-type tyrosine (1907) 657 122.8 8.2e-27
NP_002828 (OMIM: 176882) receptor-type tyrosine-pr (1997) 657 122.8 8.5e-27
XP_006719592 (OMIM: 176882) PREDICTED: receptor-ty (2012) 657 122.8 8.6e-27
NP_001317133 (OMIM: 176882) receptor-type tyrosine (2127) 657 122.8 8.9e-27
XP_011536916 (OMIM: 176882) PREDICTED: receptor-ty (2142) 657 122.8 9e-27
NP_001103224 (OMIM: 176882) receptor-type tyrosine (2215) 657 122.8 9.2e-27
XP_006719591 (OMIM: 176882) PREDICTED: receptor-ty (2230) 657 122.9 9.2e-27
NP_002839 (OMIM: 600579,614196) receptor-type tyro (1188) 653 121.9 9.3e-27
NP_109592 (OMIM: 600579,614196) receptor-type tyro (1216) 653 121.9 9.4e-27
NP_563578 (OMIM: 151460,608971,609532) receptor-ty (1145) 647 120.9 1.8e-26
XP_006711537 (OMIM: 151460,608971,609532) PREDICTE (1192) 647 120.9 1.9e-26
XP_016883102 (OMIM: 608712) PREDICTED: receptor-ty (1436) 648 121.2 1.9e-26
XP_006711536 (OMIM: 151460,608971,609532) PREDICTE (1240) 647 120.9 1.9e-26
XP_006711535 (OMIM: 151460,608971,609532) PREDICTE (1258) 647 120.9 2e-26
NP_002829 (OMIM: 151460,608971,609532) receptor-ty (1306) 647 121.0 2e-26
XP_016866637 (OMIM: 602545) PREDICTED: receptor-ty (1368) 646 120.8 2.3e-26
NP_001278913 (OMIM: 602545) receptor-type tyrosine (1439) 646 120.8 2.4e-26
NP_002835 (OMIM: 602545) receptor-type tyrosine-pr (1440) 646 120.8 2.4e-26
NP_008981 (OMIM: 608712) receptor-type tyrosine-pr (1441) 646 120.8 2.4e-26
>>NP_002823 (OMIM: 176889) tyrosine-protein phosphatase (465 aa)
initn: 3242 init1: 3242 opt: 3242 Z-score: 2977.5 bits: 560.2 E(85289): 4.1e-159
Smith-Waterman score: 3242; 99.6% identity (99.8% similar) in 465 aa overlap (1-465:1-465)
10 20 30 40 50 60
pF1KB0 MVGKAWPLTHSQGMGPWAPEGHRREAADPWWQRQQAREGRMQLGCAWVAARRGGGRKLAS
::::::::::::: ::::::::::::::::::::::.:::::::::::::::::::::::
NP_002 MVGKAWPLTHSQGTGPWAPEGHRREAADPWWQRQQAQEGRMQLGCAWVAARRGGGRKLAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 RTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 QLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 PDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARG
370 380 390 400 410 420
430 440 450 460
pF1KB0 EVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
:::::::::::::::::::::::::::::::::::::::::::::
NP_002 EVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
430 440 450 460
>>XP_016857425 (OMIM: 176889) PREDICTED: tyrosine-protei (464 aa)
initn: 1785 init1: 1785 opt: 3224 Z-score: 2961.1 bits: 557.2 E(85289): 3.4e-158
Smith-Waterman score: 3224; 99.4% identity (99.6% similar) in 465 aa overlap (1-465:1-464)
10 20 30 40 50 60
pF1KB0 MVGKAWPLTHSQGMGPWAPEGHRREAADPWWQRQQAREGRMQLGCAWVAARRGGGRKLAS
::::::::::::: ::::::::::::::::::::::.:::::::::::::::::::::::
XP_016 MVGKAWPLTHSQGTGPWAPEGHRREAADPWWQRQQAQEGRMQLGCAWVAARRGGGRKLAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 RTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_016 RTAGHPLTRWALQRQPPSPKQLEEEFL-IPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
190 200 210 220 230
250 260 270 280 290 300
pF1KB0 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB0 QLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAW
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB0 PDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARG
360 370 380 390 400 410
430 440 450 460
pF1KB0 EVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
420 430 440 450 460
>>XP_011508121 (OMIM: 176889) PREDICTED: tyrosine-protei (511 aa)
initn: 3228 init1: 3036 opt: 3036 Z-score: 2788.4 bits: 525.4 E(85289): 1.4e-148
Smith-Waterman score: 3045; 90.3% identity (90.5% similar) in 497 aa overlap (1-451:1-497)
10 20 30 40 50 60
pF1KB0 MVGKAWPLTHSQGMGPWAPEGHRREAADPWWQRQQAREGRMQLGCAWVAARRGGGRKLAS
::::::::::::: ::::::::::::::::::::::.:::::::::::::::::::::::
XP_011 MVGKAWPLTHSQGTGPWAPEGHRREAADPWWQRQQAQEGRMQLGCAWVAARRGGGRKLAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 RTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 QLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 PDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARG
370 380 390 400 410 420
430
pF1KB0 EVDILGIVCQLRLDR---------------------------------------------
:::::::::::::::
XP_011 EVDILGIVCQLRLDRLLERRKLEAQEYSWPDPRLQRSGFVPGAEWIKEDQVSTWGITPQH
430 440 450 460 470 480
440 450 460
pF1KB0 -GGMIQTAEQYQFLHHTLALYAGQLPEEPSP
::::::::::::::::
XP_011 VGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
490 500 510
>>XP_016857424 (OMIM: 176889) PREDICTED: tyrosine-protei (510 aa)
initn: 1771 init1: 1579 opt: 3018 Z-score: 2771.9 bits: 522.3 E(85289): 1.2e-147
Smith-Waterman score: 3027; 90.1% identity (90.3% similar) in 497 aa overlap (1-451:1-496)
10 20 30 40 50 60
pF1KB0 MVGKAWPLTHSQGMGPWAPEGHRREAADPWWQRQQAREGRMQLGCAWVAARRGGGRKLAS
::::::::::::: ::::::::::::::::::::::.:::::::::::::::::::::::
XP_016 MVGKAWPLTHSQGTGPWAPEGHRREAADPWWQRQQAQEGRMQLGCAWVAARRGGGRKLAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 RTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_016 RTAGHPLTRWALQRQPPSPKQLEEEFL-IPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
190 200 210 220 230
250 260 270 280 290 300
pF1KB0 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB0 QLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAW
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB0 PDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARG
360 370 380 390 400 410
430
pF1KB0 EVDILGIVCQLRLDR---------------------------------------------
:::::::::::::::
XP_016 EVDILGIVCQLRLDRLLERRKLEAQEYSWPDPRLQRSGFVPGAEWIKEDQVSTWGITPQH
420 430 440 450 460 470
440 450 460
pF1KB0 -GGMIQTAEQYQFLHHTLALYAGQLPEEPSP
::::::::::::::::
XP_016 VGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
480 490 500 510
>>NP_542155 (OMIM: 176889) tyrosine-protein phosphatase (399 aa)
initn: 2597 init1: 2597 opt: 2599 Z-score: 2389.6 bits: 451.2 E(85289): 2.3e-126
Smith-Waterman score: 2599; 96.7% identity (98.0% similar) in 394 aa overlap (72-465:9-399)
50 60 70 80 90 100
pF1KB0 QLGCAWVAARRGGGRKLASWSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPA
::. :. : . ..:::::::::::::
NP_542 MGASFWPIRQAREQQRRALS---FRQTSWLSEPPLGPA
10 20 30
110 120 130 140 150 160
pF1KB0 PHLSMVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 PHLSMVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLG
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB0 AVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 AVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDI
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB0 PGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 PGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTV
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB0 SDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 SDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQL
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB0 TIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 TIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIG
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB0 RTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 RTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPE
340 350 360 370 380 390
pF1KB0 EPSP
::::
NP_542 EPSP
>>NP_001186726 (OMIM: 176889) tyrosine-protein phosphata (434 aa)
initn: 2588 init1: 2588 opt: 2588 Z-score: 2379.1 bits: 449.4 E(85289): 8.9e-126
Smith-Waterman score: 2594; 90.1% identity (92.8% similar) in 433 aa overlap (42-465:3-434)
20 30 40 50 60
pF1KB0 QGMGPWAPEGHRREAADPWWQRQQAREGRMQLGCAWVA-----ARRGGG-RKLASWSLLS
.::: : : . ::.: :.:. . :
NP_001 MNRLGC-WPARSLPRSGRGSGQRSLGLGGHPS
10 20 30
70 80 90 100 110 120
pF1KB0 PQRQ--TDRQTDSWQEAAWGPQLLQ-QTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLTLS
:. : .:. . . .:::::::::::::::::::::::::::::::::
NP_001 GPRHPGTPAAKRTWESPGVRARDCPLSTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLTLS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB0 LGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRT
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB0 AGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVC
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB0 LGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB0 REGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPD
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB0 HQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEV
340 350 360 370 380 390
430 440 450 460
pF1KB0 DILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
:::::::::::::::::::::::::::::::::::::::::::
NP_001 DILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
400 410 420 430
>>XP_016857426 (OMIM: 176889) PREDICTED: tyrosine-protei (359 aa)
initn: 1785 init1: 1785 opt: 2451 Z-score: 2254.7 bits: 426.1 E(85289): 7.5e-119
Smith-Waterman score: 2451; 99.7% identity (99.7% similar) in 360 aa overlap (106-465:1-359)
80 90 100 110 120 130
pF1KB0 SWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLTLSLGAAMTQPPPEKT
::::::::::::::::::::::::::::::
XP_016 MVQAHGGRSRAQPLTLSLGAAMTQPPPEKT
10 20 30
140 150 160 170 180 190
pF1KB0 PAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQ
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB0 PPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYI
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSPKQLEEEFL-IPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYI
100 110 120 130 140
260 270 280 290 300 310
pF1KB0 NANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPT
150 160 170 180 190 200
320 330 340 350 360 370
pF1KB0 EEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRL
210 220 230 240 250 260
380 390 400 410 420 430
pF1KB0 VAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR
270 280 290 300 310 320
440 450 460
pF1KB0 GGMIQTAEQYQFLHHTLALYAGQLPEEPSP
::::::::::::::::::::::::::::::
XP_016 GGMIQTAEQYQFLHHTLALYAGQLPEEPSP
330 340 350
>>XP_011508125 (OMIM: 176889) PREDICTED: tyrosine-protei (311 aa)
initn: 2141 init1: 2141 opt: 2141 Z-score: 1971.7 bits: 373.5 E(85289): 4.4e-103
Smith-Waterman score: 2141; 99.3% identity (99.7% similar) in 307 aa overlap (1-307:1-307)
10 20 30 40 50 60
pF1KB0 MVGKAWPLTHSQGMGPWAPEGHRREAADPWWQRQQAREGRMQLGCAWVAARRGGGRKLAS
::::::::::::: ::::::::::::::::::::::.:::::::::::::::::::::::
XP_011 MVGKAWPLTHSQGTGPWAPEGHRREAADPWWQRQQAQEGRMQLGCAWVAARRGGGRKLAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 RTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 QLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAW
:::::::
XP_011 QLREGKELPPS
310
>>XP_011508122 (OMIM: 176889) PREDICTED: tyrosine-protei (400 aa)
initn: 2322 init1: 2130 opt: 2130 Z-score: 1960.1 bits: 371.8 E(85289): 1.9e-102
Smith-Waterman score: 2139; 87.4% identity (87.6% similar) in 372 aa overlap (126-451:15-386)
100 110 120 130 140 150
pF1KB0 PPLGPAPHLSMVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALML
.:::::::::::::::::::::::::::::
XP_011 MGVPWCEGQRLSTVSMTQPPPEKTPAKKHVRLQERRGSNVALML
10 20 30 40
160 170 180 190 200 210
pF1KB0 DVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVS
50 60 70 80 90 100
220 230 240 250 260 270
pF1KB0 PEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQG
110 120 130 140 150 160
280 290 300 310 320 330
pF1KB0 PMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPE
170 180 190 200 210 220
340 350 360 370 380 390
pF1KB0 YTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVH
230 240 250 260 270 280
400 410 420 430
pF1KB0 CSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR--------------------
::::::::::::::::::::::::::::::::::::::::
XP_011 CSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRLLERRKLEAQEYSWPDPRLQ
290 300 310 320 330 340
440 450 460
pF1KB0 --------------------------GGMIQTAEQYQFLHHTLALYAGQLPEEPSP
::::::::::::::::
XP_011 RSGFVPGAEWIKEDQVSTWGITPQHVGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
350 360 370 380 390 400
>>XP_011508123 (OMIM: 176889) PREDICTED: tyrosine-protei (354 aa)
initn: 2079 init1: 1887 opt: 1887 Z-score: 1738.3 bits: 330.6 E(85289): 4.4e-90
Smith-Waterman score: 1896; 86.2% identity (86.2% similar) in 334 aa overlap (164-451:7-340)
140 150 160 170 180 190
pF1KB0 KTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQ
::::::::::::::::::::::::::::::
XP_011 MCDCRREPICSVNTPREVTLHFLRTAGHPLTRWALQ
10 20 30
200 210 220 230 240 250
pF1KB0 RQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGD
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB0 YINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYW
100 110 120 130 140 150
320 330 340 350 360 370
pF1KB0 PTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLL
160 170 180 190 200 210
380 390 400 410 420 430
pF1KB0 RLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRL
220 230 240 250 260 270
440
pF1KB0 DR----------------------------------------------GGMIQTAEQYQF
:: ::::::::::::
XP_011 DRLLERRKLEAQEYSWPDPRLQRSGFVPGAEWIKEDQVSTWGITPQHVGGMIQTAEQYQF
280 290 300 310 320 330
450 460
pF1KB0 LHHTLALYAGQLPEEPSP
::::
XP_011 LHHTLALYAGQLPEEPSP
340 350
465 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:50:43 2016 done: Sat Nov 5 11:50:44 2016
Total Scan time: 9.700 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]