Result of FASTA (omim) for
pFN21AB8561
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8561, 967 aa
1>>>pF1KB8561 967 - 967 aa - 967 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.0877+/-0.000575; mu= 1.4634+/- 0.035
mean_var=681.6520+/-155.534, 0's: 0 Z-trim(117.7): 1160 B-trim: 33 in 1/59
Lambda= 0.049124
statistics sampled from 28395 (29909) to 28395 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.351), width: 16
Scan time: 14.720
The best scores are: opt bits E(85289)
NP_775267 (OMIM: 601212) protein-tyrosine kinase 2 ( 967) 6482 476.5 2.8e-133
XP_005273505 (OMIM: 601212) PREDICTED: protein-tyr ( 997) 5012 372.4 6.5e-102
XP_016868703 (OMIM: 601212) PREDICTED: protein-tyr (1009) 5012 372.4 6.6e-102
XP_011542743 (OMIM: 601212) PREDICTED: protein-tyr (1009) 5012 372.4 6.6e-102
NP_004094 (OMIM: 601212) protein-tyrosine kinase 2 (1009) 5012 372.4 6.6e-102
NP_775266 (OMIM: 601212) protein-tyrosine kinase 2 (1009) 5012 372.4 6.6e-102
XP_005273504 (OMIM: 601212) PREDICTED: protein-tyr (1009) 5012 372.4 6.6e-102
NP_775268 (OMIM: 601212) protein-tyrosine kinase 2 (1009) 5012 372.4 6.6e-102
XP_016868705 (OMIM: 601212) PREDICTED: protein-tyr ( 984) 2546 197.6 2.6e-49
XP_016868704 (OMIM: 601212) PREDICTED: protein-tyr ( 996) 2546 197.6 2.7e-49
XP_011542744 (OMIM: 601212) PREDICTED: protein-tyr ( 996) 2546 197.6 2.7e-49
XP_016869148 (OMIM: 600758) PREDICTED: focal adhes (1031) 2266 177.8 2.5e-43
XP_016869165 (OMIM: 600758) PREDICTED: focal adhes (1034) 2266 177.8 2.6e-43
NP_722560 (OMIM: 600758) focal adhesion kinase 1 i (1052) 2266 177.8 2.6e-43
XP_016869162 (OMIM: 600758) PREDICTED: focal adhes (1052) 2266 177.8 2.6e-43
XP_016869160 (OMIM: 600758) PREDICTED: focal adhes (1055) 2266 177.8 2.6e-43
XP_016869161 (OMIM: 600758) PREDICTED: focal adhes (1055) 2266 177.8 2.6e-43
NP_001186578 (OMIM: 600758) focal adhesion kinase (1065) 2266 177.8 2.6e-43
NP_005598 (OMIM: 600758) focal adhesion kinase 1 i (1074) 2266 177.8 2.6e-43
XP_016869146 (OMIM: 600758) PREDICTED: focal adhes (1099) 2266 177.8 2.6e-43
XP_016869175 (OMIM: 600758) PREDICTED: focal adhes ( 942) 2053 162.6 8.5e-39
XP_016869174 (OMIM: 600758) PREDICTED: focal adhes ( 948) 1438 119.1 1.1e-25
XP_016869159 (OMIM: 600758) PREDICTED: focal adhes (1058) 1438 119.1 1.2e-25
XP_016869154 (OMIM: 600758) PREDICTED: focal adhes (1061) 1438 119.1 1.2e-25
XP_016869153 (OMIM: 600758) PREDICTED: focal adhes (1061) 1438 119.1 1.2e-25
XP_016869167 (OMIM: 600758) PREDICTED: focal adhes (1016) 1409 117.1 4.9e-25
XP_016869155 (OMIM: 600758) PREDICTED: focal adhes (1060) 1409 117.1 5e-25
XP_016869173 (OMIM: 600758) PREDICTED: focal adhes ( 949) 1400 116.4 7.3e-25
XP_016869158 (OMIM: 600758) PREDICTED: focal adhes (1059) 1400 116.4 7.7e-25
XP_016869151 (OMIM: 600758) PREDICTED: focal adhes (1062) 1400 116.4 7.7e-25
XP_016869152 (OMIM: 600758) PREDICTED: focal adhes (1062) 1400 116.4 7.7e-25
XP_016869145 (OMIM: 600758) PREDICTED: focal adhes (1103) 1400 116.5 7.9e-25
XP_016869143 (OMIM: 600758) PREDICTED: focal adhes (1106) 1400 116.5 7.9e-25
XP_016869179 (OMIM: 600758) PREDICTED: focal adhes ( 913) 1354 113.1 6.9e-24
XP_016869171 (OMIM: 600758) PREDICTED: focal adhes ( 976) 1243 105.3 1.7e-21
XP_016869147 (OMIM: 600758) PREDICTED: focal adhes (1089) 1243 105.3 1.7e-21
XP_016869178 (OMIM: 600758) PREDICTED: focal adhes ( 919) 1212 103.0 7.4e-21
XP_016869177 (OMIM: 600758) PREDICTED: focal adhes ( 919) 1212 103.0 7.4e-21
XP_016869176 (OMIM: 600758) PREDICTED: focal adhes ( 934) 1212 103.0 7.4e-21
XP_016869172 (OMIM: 600758) PREDICTED: focal adhes ( 955) 1212 103.0 7.5e-21
NP_001303271 (OMIM: 600758) focal adhesion kinase ( 955) 1212 103.0 7.5e-21
XP_016869170 (OMIM: 600758) PREDICTED: focal adhes ( 980) 1212 103.1 7.6e-21
XP_006716672 (OMIM: 600758) PREDICTED: focal adhes ( 983) 1212 103.1 7.6e-21
XP_006716673 (OMIM: 600758) PREDICTED: focal adhes ( 983) 1212 103.1 7.6e-21
XP_005251070 (OMIM: 600758) PREDICTED: focal adhes ( 983) 1212 103.1 7.6e-21
XP_016869169 (OMIM: 600758) PREDICTED: focal adhes ( 995) 1212 103.1 7.7e-21
XP_016869168 (OMIM: 600758) PREDICTED: focal adhes (1011) 1212 103.1 7.7e-21
XP_016869166 (OMIM: 600758) PREDICTED: focal adhes (1032) 1212 103.1 7.8e-21
XP_016869164 (OMIM: 600758) PREDICTED: focal adhes (1047) 1212 103.1 7.9e-21
XP_016869163 (OMIM: 600758) PREDICTED: focal adhes (1047) 1212 103.1 7.9e-21
>>NP_775267 (OMIM: 601212) protein-tyrosine kinase 2-bet (967 aa)
initn: 6482 init1: 6482 opt: 6482 Z-score: 2513.8 bits: 476.5 E(85289): 2.8e-133
Smith-Waterman score: 6482; 99.9% identity (99.9% similar) in 967 aa overlap (1-967:1-967)
10 20 30 40 50 60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 KYRPPPQTNLLAPKLQFQEEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 KYRPPPQTNLLAPKLQFQEEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 RQEEKSLDPMVYMNDTSPLTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYL
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
NP_775 RQEEKSLDPMVYMNDKSPLTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB8 NVMELVRAVLELKNELCQLPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 NVMELVRAVLELKNELCQLPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB8 QKLLNKDLAELINKMRLAQQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 QKLLNKDLAELINKMRLAQQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLAN
910 920 930 940 950 960
pF1KB8 LAHPPAE
:::::::
NP_775 LAHPPAE
>>XP_005273505 (OMIM: 601212) PREDICTED: protein-tyrosin (997 aa)
initn: 6069 init1: 5012 opt: 5012 Z-score: 1950.6 bits: 372.4 E(85289): 6.5e-102
Smith-Waterman score: 6275; 94.6% identity (94.6% similar) in 1009 aa overlap (1-967:1-997)
10 20 30 40 50 60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
670 680 690 700 710 720
730
pF1KB8 KYRPPPQTNLLAPKLQFQ------------------------------------------
::::::::::::::::::
XP_005 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
730 740 750 760 770 780
740 750 760 770 780 790
pF1KB8 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDTSP
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSL-----------
790 800 810 820
800 810 820 830 840 850
pF1KB8 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 -TPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
830 840 850 860 870 880
860 870 880 890 900 910
pF1KB8 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
890 900 910 920 930 940
920 930 940 950 960
pF1KB8 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
950 960 970 980 990
>>XP_016868703 (OMIM: 601212) PREDICTED: protein-tyrosin (1009 aa)
initn: 5012 init1: 5012 opt: 5012 Z-score: 1950.6 bits: 372.4 E(85289): 6.6e-102
Smith-Waterman score: 6320; 95.7% identity (95.7% similar) in 999 aa overlap (1-957:1-999)
10 20 30 40 50 60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
670 680 690 700 710 720
730
pF1KB8 KYRPPPQTNLLAPKLQFQ------------------------------------------
::::::::::::::::::
XP_016 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
730 740 750 760 770 780
740 750 760 770 780 790
pF1KB8 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
790 800 810 820 830 840
800 810 820 830 840 850
pF1KB8 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
850 860 870 880 890 900
860 870 880 890 900 910
pF1KB8 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
910 920 930 940 950 960
920 930 940 950 960
pF1KB8 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
:::::::::::::::::::::::::::::::::::::::
XP_016 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
970 980 990 1000
>>XP_011542743 (OMIM: 601212) PREDICTED: protein-tyrosin (1009 aa)
initn: 5012 init1: 5012 opt: 5012 Z-score: 1950.6 bits: 372.4 E(85289): 6.6e-102
Smith-Waterman score: 6320; 95.7% identity (95.7% similar) in 999 aa overlap (1-957:1-999)
10 20 30 40 50 60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
670 680 690 700 710 720
730
pF1KB8 KYRPPPQTNLLAPKLQFQ------------------------------------------
::::::::::::::::::
XP_011 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
730 740 750 760 770 780
740 750 760 770 780 790
pF1KB8 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_011 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
790 800 810 820 830 840
800 810 820 830 840 850
pF1KB8 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
850 860 870 880 890 900
860 870 880 890 900 910
pF1KB8 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
910 920 930 940 950 960
920 930 940 950 960
pF1KB8 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
:::::::::::::::::::::::::::::::::::::::
XP_011 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
970 980 990 1000
>>NP_004094 (OMIM: 601212) protein-tyrosine kinase 2-bet (1009 aa)
initn: 5012 init1: 5012 opt: 5012 Z-score: 1950.6 bits: 372.4 E(85289): 6.6e-102
Smith-Waterman score: 6320; 95.7% identity (95.7% similar) in 999 aa overlap (1-957:1-999)
10 20 30 40 50 60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
670 680 690 700 710 720
730
pF1KB8 KYRPPPQTNLLAPKLQFQ------------------------------------------
::::::::::::::::::
NP_004 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
730 740 750 760 770 780
740 750 760 770 780 790
pF1KB8 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_004 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
790 800 810 820 830 840
800 810 820 830 840 850
pF1KB8 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
850 860 870 880 890 900
860 870 880 890 900 910
pF1KB8 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
910 920 930 940 950 960
920 930 940 950 960
pF1KB8 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
:::::::::::::::::::::::::::::::::::::::
NP_004 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
970 980 990 1000
>>NP_775266 (OMIM: 601212) protein-tyrosine kinase 2-bet (1009 aa)
initn: 5012 init1: 5012 opt: 5012 Z-score: 1950.6 bits: 372.4 E(85289): 6.6e-102
Smith-Waterman score: 6320; 95.7% identity (95.7% similar) in 999 aa overlap (1-957:1-999)
10 20 30 40 50 60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
670 680 690 700 710 720
730
pF1KB8 KYRPPPQTNLLAPKLQFQ------------------------------------------
::::::::::::::::::
NP_775 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
730 740 750 760 770 780
740 750 760 770 780 790
pF1KB8 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_775 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
790 800 810 820 830 840
800 810 820 830 840 850
pF1KB8 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
850 860 870 880 890 900
860 870 880 890 900 910
pF1KB8 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
910 920 930 940 950 960
920 930 940 950 960
pF1KB8 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
:::::::::::::::::::::::::::::::::::::::
NP_775 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
970 980 990 1000
>>XP_005273504 (OMIM: 601212) PREDICTED: protein-tyrosin (1009 aa)
initn: 5012 init1: 5012 opt: 5012 Z-score: 1950.6 bits: 372.4 E(85289): 6.6e-102
Smith-Waterman score: 6320; 95.7% identity (95.7% similar) in 999 aa overlap (1-957:1-999)
10 20 30 40 50 60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
670 680 690 700 710 720
730
pF1KB8 KYRPPPQTNLLAPKLQFQ------------------------------------------
::::::::::::::::::
XP_005 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
730 740 750 760 770 780
740 750 760 770 780 790
pF1KB8 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_005 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
790 800 810 820 830 840
800 810 820 830 840 850
pF1KB8 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
850 860 870 880 890 900
860 870 880 890 900 910
pF1KB8 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
910 920 930 940 950 960
920 930 940 950 960
pF1KB8 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
:::::::::::::::::::::::::::::::::::::::
XP_005 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
970 980 990 1000
>>NP_775268 (OMIM: 601212) protein-tyrosine kinase 2-bet (1009 aa)
initn: 5012 init1: 5012 opt: 5012 Z-score: 1950.6 bits: 372.4 E(85289): 6.6e-102
Smith-Waterman score: 6320; 95.7% identity (95.7% similar) in 999 aa overlap (1-957:1-999)
10 20 30 40 50 60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
670 680 690 700 710 720
730
pF1KB8 KYRPPPQTNLLAPKLQFQ------------------------------------------
::::::::::::::::::
NP_775 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
730 740 750 760 770 780
740 750 760 770 780 790
pF1KB8 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_775 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
790 800 810 820 830 840
800 810 820 830 840 850
pF1KB8 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
850 860 870 880 890 900
860 870 880 890 900 910
pF1KB8 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
910 920 930 940 950 960
920 930 940 950 960
pF1KB8 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
:::::::::::::::::::::::::::::::::::::::
NP_775 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
970 980 990 1000
>>XP_016868705 (OMIM: 601212) PREDICTED: protein-tyrosin (984 aa)
initn: 3603 init1: 2546 opt: 2546 Z-score: 1006.1 bits: 197.6 E(85289): 2.6e-49
Smith-Waterman score: 6147; 93.4% identity (93.4% similar) in 1009 aa overlap (1-967:1-984)
10 20 30 40 50 60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQ-----
310 320 330 340 350
370 380 390 400 410 420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --------DGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
360 370 380 390 400
430 440 450 460 470 480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
650 660 670 680 690 700
730
pF1KB8 KYRPPPQTNLLAPKLQFQ------------------------------------------
::::::::::::::::::
XP_016 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
710 720 730 740 750 760
740 750 760 770 780 790
pF1KB8 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDTSP
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSL-----------
770 780 790 800 810
800 810 820 830 840 850
pF1KB8 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -TPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
820 830 840 850 860 870
860 870 880 890 900 910
pF1KB8 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
880 890 900 910 920 930
920 930 940 950 960
pF1KB8 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
940 950 960 970 980
>>XP_016868704 (OMIM: 601212) PREDICTED: protein-tyrosin (996 aa)
initn: 3846 init1: 2546 opt: 2546 Z-score: 1006.1 bits: 197.6 E(85289): 2.7e-49
Smith-Waterman score: 6192; 94.4% identity (94.4% similar) in 999 aa overlap (1-957:1-986)
10 20 30 40 50 60
pF1KB8 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQ-----
310 320 330 340 350
370 380 390 400 410 420
pF1KB8 SLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --------DGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGI
360 370 380 390 400
430 440 450 460 470 480
pF1KB8 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB8 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB8 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFR
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB8 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB8 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRP
650 660 670 680 690 700
730
pF1KB8 KYRPPPQTNLLAPKLQFQ------------------------------------------
::::::::::::::::::
XP_016 KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
710 720 730 740 750 760
740 750 760 770 780 790
pF1KB8 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 EEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
770 780 790 800 810 820
800 810 820 830 840 850
pF1KB8 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQ
830 840 850 860 870 880
860 870 880 890 900 910
pF1KB8 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
890 900 910 920 930 940
920 930 940 950 960
pF1KB8 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
:::::::::::::::::::::::::::::::::::::::
XP_016 QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
950 960 970 980 990
967 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:49:02 2016 done: Sat Nov 5 11:49:04 2016
Total Scan time: 14.720 Total Display time: 0.410
Function used was FASTA [36.3.4 Apr, 2011]