Result of FASTA (omim) for
pFN21AB6570
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6570, 400 aa
1>>>pF1KB6570 400 - 400 aa - 400 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6331+/-0.000362; mu= 15.5849+/- 0.023
mean_var=77.2689+/-15.544, 0's: 0 Z-trim(113.9): 9 B-trim: 0 in 0/55
Lambda= 0.145906
statistics sampled from 23512 (23519) to 23512 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.663), E-opt: 0.2 (0.276), width: 16
Scan time: 8.900
The best scores are: opt bits E(85289)
NP_002452 (OMIM: 603236,614714) diphosphomevalonat ( 400) 2677 573.1 4.1e-163
XP_011521390 (OMIM: 603236,614714) PREDICTED: diph ( 379) 2519 539.8 4.1e-153
XP_011521391 (OMIM: 603236,614714) PREDICTED: diph ( 283) 1790 386.3 5e-107
XP_011521389 (OMIM: 603236,614714) PREDICTED: diph ( 413) 1790 386.4 6.8e-107
XP_011521388 (OMIM: 603236,614714) PREDICTED: diph ( 434) 1790 386.4 7.1e-107
>>NP_002452 (OMIM: 603236,614714) diphosphomevalonate de (400 aa)
initn: 2677 init1: 2677 opt: 2677 Z-score: 3049.3 bits: 573.1 E(85289): 4.1e-163
Smith-Waterman score: 2677; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KB6 MASEKPLAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MASEKPLAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 AAGLASSAAGYACLAYTLARVYGVESDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AAGLASSAAGYACLAYTLARVYGVESDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 SIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLLRFRAESVVPARMAEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLLRFRAESVVPARMAEM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 ARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 AYTFDAGPNAVIFTLDDTVAEFVAAVWHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AYTFDAGPNAVIFTLDDTVAEFVAAVWHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAM
310 320 330 340 350 360
370 380 390 400
pF1KB6 EPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKPAA
::::::::::::::::::::::::::::::::::::::::
NP_002 EPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKPAA
370 380 390 400
>>XP_011521390 (OMIM: 603236,614714) PREDICTED: diphosph (379 aa)
initn: 2519 init1: 2519 opt: 2519 Z-score: 2869.9 bits: 539.8 E(85289): 4.1e-153
Smith-Waterman score: 2519; 100.0% identity (100.0% similar) in 376 aa overlap (25-400:4-379)
10 20 30 40 50 60
pF1KB6 MASEKPLAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDF
::::::::::::::::::::::::::::::::::::
XP_011 MNRGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDF
10 20 30
70 80 90 100 110 120
pF1KB6 TEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPT
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 AAGLASSAAGYACLAYTLARVYGVESDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAGLASSAAGYACLAYTLARVYGVESDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKD
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB6 SIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLLRFRAESVVPARMAEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLLRFRAESVVPARMAEM
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 ARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKV
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 AYTFDAGPNAVIFTLDDTVAEFVAAVWHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYTFDAGPNAVIFTLDDTVAEFVAAVWHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAM
280 290 300 310 320 330
370 380 390 400
pF1KB6 EPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKPAA
::::::::::::::::::::::::::::::::::::::::
XP_011 EPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKPAA
340 350 360 370
>>XP_011521391 (OMIM: 603236,614714) PREDICTED: diphosph (283 aa)
initn: 1790 init1: 1790 opt: 1790 Z-score: 2042.5 bits: 386.3 E(85289): 5e-107
Smith-Waterman score: 1790; 100.0% identity (100.0% similar) in 265 aa overlap (136-400:19-283)
110 120 130 140 150 160
pF1KB6 LSCKVHVASVNNFPTAAGLASSAAGYACLAYTLARVYGVESDLSEVARRGSGSACRSLYG
::::::::::::::::::::::::::::::
XP_011 MGEKHCRPGVQDQPGQHTYTLARVYGVESDLSEVARRGSGSACRSLYG
10 20 30 40
170 180 190 200 210 220
pF1KB6 GFVEWQMGEQADGKDSIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFVEWQMGEQADGKDSIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLL
50 60 70 80 90 100
230 240 250 260 270 280
pF1KB6 RFRAESVVPARMAEMARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISYLNAISWRII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFRAESVVPARMAEMARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISYLNAISWRII
110 120 130 140 150 160
290 300 310 320 330 340
pF1KB6 HLVHRFNAHHGDTKVAYTFDAGPNAVIFTLDDTVAEFVAAVWHGFPPGSNGDTFLKGLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLVHRFNAHHGDTKVAYTFDAGPNAVIFTLDDTVAEFVAAVWHGFPPGSNGDTFLKGLQV
170 180 190 200 210 220
350 360 370 380 390 400
pF1KB6 RPAPLSAELQAALAMEPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKPAA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPAPLSAELQAALAMEPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKPAA
230 240 250 260 270 280
>>XP_011521389 (OMIM: 603236,614714) PREDICTED: diphosph (413 aa)
initn: 2500 init1: 1790 opt: 1790 Z-score: 2040.1 bits: 386.4 E(85289): 6.8e-107
Smith-Waterman score: 2436; 91.5% identity (91.7% similar) in 410 aa overlap (25-400:4-413)
10 20 30 40 50 60
pF1KB6 MASEKPLAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDF
::::::::::::::::::::::::::::::::::::
XP_011 MNRGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDF
10 20 30
70 80 90 100 110 120
pF1KB6 TEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPT
40 50 60 70 80 90
130 140
pF1KB6 AAGLASSAAGYACLA----------------------------------YTLARVYGVES
::::::::::::::. :::::::::::
XP_011 AAGLASSAAGYACLVAAGVGLSPVIPVLKRLMGEKHCRPGVQDQPGQHTYTLARVYGVES
100 110 120 130 140 150
150 160 170 180 190 200
pF1KB6 DLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQVAPESHWPELRVLILVVSAEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQVAPESHWPELRVLILVVSAEK
160 170 180 190 200 210
210 220 230 240 250 260
pF1KB6 KLTGSTVGMRASVETSPLLRFRAESVVPARMAEMARCIRERDFPSFAQLTMKDSNQFHAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLTGSTVGMRASVETSPLLRFRAESVVPARMAEMARCIRERDFPSFAQLTMKDSNQFHAT
220 230 240 250 260 270
270 280 290 300 310 320
pF1KB6 CLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKVAYTFDAGPNAVIFTLDDTVAEFVAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKVAYTFDAGPNAVIFTLDDTVAEFVAAV
280 290 300 310 320 330
330 340 350 360 370 380
pF1KB6 WHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAMEPTPGGVKYIIVTQVGPGPQILDDPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAMEPTPGGVKYIIVTQVGPGPQILDDPC
340 350 360 370 380 390
390 400
pF1KB6 AHLLGPDGLPKPAA
::::::::::::::
XP_011 AHLLGPDGLPKPAA
400 410
>>XP_011521388 (OMIM: 603236,614714) PREDICTED: diphosph (434 aa)
initn: 2658 init1: 1790 opt: 1790 Z-score: 2039.7 bits: 386.4 E(85289): 7.1e-107
Smith-Waterman score: 2582; 91.9% identity (92.1% similar) in 432 aa overlap (3-400:3-434)
10 20 30 40 50 60
pF1KB6 MASEKPLAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASEKPLAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPT
70 80 90 100 110 120
130 140
pF1KB6 AAGLASSAAGYACLA----------------------------------YTLARVYGVES
::::::::::::::. :::::::::::
XP_011 AAGLASSAAGYACLVAAGVGLSPVIPVLKRLMGEKHCRPGVQDQPGQHTYTLARVYGVES
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB6 DLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQVAPESHWPELRVLILVVSAEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQVAPESHWPELRVLILVVSAEK
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB6 KLTGSTVGMRASVETSPLLRFRAESVVPARMAEMARCIRERDFPSFAQLTMKDSNQFHAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLTGSTVGMRASVETSPLLRFRAESVVPARMAEMARCIRERDFPSFAQLTMKDSNQFHAT
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB6 CLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKVAYTFDAGPNAVIFTLDDTVAEFVAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKVAYTFDAGPNAVIFTLDDTVAEFVAAV
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB6 WHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAMEPTPGGVKYIIVTQVGPGPQILDDPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAMEPTPGGVKYIIVTQVGPGPQILDDPC
370 380 390 400 410 420
390 400
pF1KB6 AHLLGPDGLPKPAA
::::::::::::::
XP_011 AHLLGPDGLPKPAA
430
400 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:29:20 2016 done: Sat Nov 5 11:29:22 2016
Total Scan time: 8.900 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]