Result of FASTA (omim) for
pFN21AB6548
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6548, 392 aa
1>>>pF1KB6548 392 - 392 aa - 392 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.9915+/-0.000332; mu= 0.9232+/- 0.021
mean_var=208.9687+/-41.020, 0's: 0 Z-trim(122.1): 7 B-trim: 0 in 0/57
Lambda= 0.088722
statistics sampled from 39578 (39585) to 39578 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.788), E-opt: 0.2 (0.464), width: 16
Scan time: 9.160
The best scores are: opt bits E(85289)
NP_071905 (OMIM: 609359) HCLS1-binding protein 3 [ ( 392) 2589 343.6 4.9e-94
XP_016860189 (OMIM: 609359) PREDICTED: HCLS1-bindi ( 359) 2375 316.2 8.1e-86
XP_016860187 (OMIM: 609359) PREDICTED: HCLS1-bindi ( 388) 2016 270.2 5.9e-72
XP_016860186 (OMIM: 609359) PREDICTED: HCLS1-bindi ( 395) 2016 270.2 5.9e-72
XP_016860185 (OMIM: 609359) PREDICTED: HCLS1-bindi ( 396) 2016 270.2 6e-72
XP_016860190 (OMIM: 609359) PREDICTED: HCLS1-bindi ( 313) 2009 269.3 9.2e-72
XP_016860188 (OMIM: 609359) PREDICTED: HCLS1-bindi ( 363) 1802 242.8 9.8e-64
>>NP_071905 (OMIM: 609359) HCLS1-binding protein 3 [Homo (392 aa)
initn: 2589 init1: 2589 opt: 2589 Z-score: 1809.2 bits: 343.6 E(85289): 4.9e-94
Smith-Waterman score: 2589; 99.7% identity (100.0% similar) in 392 aa overlap (1-392:1-392)
10 20 30 40 50 60
pF1KB6 MQSPAVLVTSRRLQNAHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MQSPAVLVTSRRLQNAHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 DVVQFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESDIRERRAVFNEILRCVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 DVVQFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESDIRERRAVFNEILRCVS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KDAELAGSPELLEFLGTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 KDAELAGSPELLEFLGTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 PPVQSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 PPVQSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LFGPGRKLSPQDPSEDVSSMDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRD
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
NP_071 LFGPGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 ASKELFRVEEDLDQILNLGAEPKPKPQLKPKPPVAAKPVIPRKPAVPPKAGPAEAVAGQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 ASKELFRVEEDLDQILNLGAEPKPKPQLKPKPPVAAKPVIPRKPAVPPKAGPAEAVAGQQ
310 320 330 340 350 360
370 380 390
pF1KB6 KPQEQIQAMDEMDILQYIQDHDTPAQAAPSLF
::::::::::::::::::::::::::::::::
NP_071 KPQEQIQAMDEMDILQYIQDHDTPAQAAPSLF
370 380 390
>>XP_016860189 (OMIM: 609359) PREDICTED: HCLS1-binding p (359 aa)
initn: 2375 init1: 2375 opt: 2375 Z-score: 1661.7 bits: 316.2 E(85289): 8.1e-86
Smith-Waterman score: 2375; 99.7% identity (100.0% similar) in 359 aa overlap (34-392:1-359)
10 20 30 40 50 60
pF1KB6 PAVLVTSRRLQNAHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPEDVV
::::::::::::::::::::::::::::::
XP_016 MMSGHVEYQILVVTRLAAFKSAKHRPEDVV
10 20 30
70 80 90 100 110 120
pF1KB6 QFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESDIRERRAVFNEILRCVSKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESDIRERRAVFNEILRCVSKDA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 ELAGSPELLEFLGTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEGPPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAGSPELLEFLGTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEGPPV
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB6 QSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEGLFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEGLFG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 PGRKLSPQDPSEDVSSMDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRDASK
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
XP_016 PGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRDASK
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 ELFRVEEDLDQILNLGAEPKPKPQLKPKPPVAAKPVIPRKPAVPPKAGPAEAVAGQQKPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELFRVEEDLDQILNLGAEPKPKPQLKPKPPVAAKPVIPRKPAVPPKAGPAEAVAGQQKPQ
280 290 300 310 320 330
370 380 390
pF1KB6 EQIQAMDEMDILQYIQDHDTPAQAAPSLF
:::::::::::::::::::::::::::::
XP_016 EQIQAMDEMDILQYIQDHDTPAQAAPSLF
340 350
>>XP_016860187 (OMIM: 609359) PREDICTED: HCLS1-binding p (388 aa)
initn: 2032 init1: 2009 opt: 2016 Z-score: 1412.9 bits: 270.2 E(85289): 5.9e-72
Smith-Waterman score: 2016; 90.2% identity (94.2% similar) in 347 aa overlap (1-344:1-347)
10 20 30 40 50 60
pF1KB6 MQSPAVLVTSRRLQNAHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQSPAVLVTSRRLQNAHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 DVVQFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESDIRERRAVFNEILRCVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVVQFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESDIRERRAVFNEILRCVS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KDAELAGSPELLEFLGTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDAELAGSPELLEFLGTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 PPVQSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPVQSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LFGPGRKLSPQDPSEDVSSMDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRD
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_016 LFGPGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRD
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 ASKELFRV--EEDLDQILNLGAEPKPKPQLKP-KPPVAAKPVIPRKPAVPPKAGPAEAVA
:::::::. .. .. . .:. :.: . .::. .: :
XP_016 ASKELFRTLAHKGFQCAQSNCLLTSPRIPLQPSRRTTAASSSLPLPPGSWAGVEEEAPLQ
310 320 330 340 350 360
360 370 380 390
pF1KB6 GQQKPQEQIQAMDEMDILQYIQDHDTPAQAAPSLF
XP_016 IQYGERNLMASTRILKTTAHQFASLHKR
370 380
>>XP_016860186 (OMIM: 609359) PREDICTED: HCLS1-binding p (395 aa)
initn: 2032 init1: 2009 opt: 2016 Z-score: 1412.8 bits: 270.2 E(85289): 5.9e-72
Smith-Waterman score: 2016; 90.2% identity (94.2% similar) in 347 aa overlap (1-344:1-347)
10 20 30 40 50 60
pF1KB6 MQSPAVLVTSRRLQNAHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQSPAVLVTSRRLQNAHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 DVVQFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESDIRERRAVFNEILRCVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVVQFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESDIRERRAVFNEILRCVS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KDAELAGSPELLEFLGTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDAELAGSPELLEFLGTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 PPVQSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPVQSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LFGPGRKLSPQDPSEDVSSMDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRD
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_016 LFGPGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRD
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 ASKELFRV--EEDLDQILNLGAEPKPKPQLKP-KPPVAAKPVIPRKPAVPPKAGPAEAVA
:::::::. .. .. . .:. :.: . .::. .: :
XP_016 ASKELFRTLAHKGFQCAQSNCLLTSPRIPLQPSRRTTAASSSLPLPPGSWAGVEEEAPLQ
310 320 330 340 350 360
360 370 380 390
pF1KB6 GQQKPQEQIQAMDEMDILQYIQDHDTPAQAAPSLF
XP_016 IQYGERTVLHFQIISSPLCTPIPGCWCQEESNPLN
370 380 390
>>XP_016860185 (OMIM: 609359) PREDICTED: HCLS1-binding p (396 aa)
initn: 2032 init1: 2009 opt: 2016 Z-score: 1412.7 bits: 270.2 E(85289): 6e-72
Smith-Waterman score: 2016; 90.2% identity (94.2% similar) in 347 aa overlap (1-344:1-347)
10 20 30 40 50 60
pF1KB6 MQSPAVLVTSRRLQNAHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQSPAVLVTSRRLQNAHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 DVVQFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESDIRERRAVFNEILRCVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVVQFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESDIRERRAVFNEILRCVS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KDAELAGSPELLEFLGTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDAELAGSPELLEFLGTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 PPVQSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPVQSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LFGPGRKLSPQDPSEDVSSMDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRD
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_016 LFGPGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRD
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 ASKELFRV--EEDLDQILNLGAEPKPKPQLKP-KPPVAAKPVIPRKPAVPPKAGPAEAVA
:::::::. .. .. . .:. :.: . .::. .: :
XP_016 ASKELFRTLAHKGFQCAQSNCLLTSPRIPLQPSRRTTAASSSLPLPPGSWAGVEEEAPLQ
310 320 330 340 350 360
360 370 380 390
pF1KB6 GQQKPQEQIQAMDEMDILQYIQDHDTPAQAAPSLF
XP_016 IQYGESFLRGTQRLPEGSFPLLIVDKGWLLYPIQML
370 380 390
>>XP_016860190 (OMIM: 609359) PREDICTED: HCLS1-binding p (313 aa)
initn: 2031 init1: 2009 opt: 2009 Z-score: 1409.4 bits: 269.3 E(85289): 9.2e-72
Smith-Waterman score: 2009; 99.7% identity (100.0% similar) in 307 aa overlap (1-307:1-307)
10 20 30 40 50 60
pF1KB6 MQSPAVLVTSRRLQNAHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQSPAVLVTSRRLQNAHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 DVVQFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESDIRERRAVFNEILRCVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVVQFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESDIRERRAVFNEILRCVS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KDAELAGSPELLEFLGTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDAELAGSPELLEFLGTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 PPVQSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPVQSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LFGPGRKLSPQDPSEDVSSMDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRD
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_016 LFGPGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 ASKELFRVEEDLDQILNLGAEPKPKPQLKPKPPVAAKPVIPRKPAVPPKAGPAEAVAGQQ
:::::::
XP_016 ASKELFRQIQKEP
310
>>XP_016860188 (OMIM: 609359) PREDICTED: HCLS1-binding p (363 aa)
initn: 1818 init1: 1795 opt: 1802 Z-score: 1265.2 bits: 242.8 E(85289): 9.8e-64
Smith-Waterman score: 1802; 89.2% identity (93.6% similar) in 314 aa overlap (34-344:1-314)
10 20 30 40 50 60
pF1KB6 PAVLVTSRRLQNAHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPEDVV
::::::::::::::::::::::::::::::
XP_016 MMSGHVEYQILVVTRLAAFKSAKHRPEDVV
10 20 30
70 80 90 100 110 120
pF1KB6 QFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESDIRERRAVFNEILRCVSKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESDIRERRAVFNEILRCVSKDA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 ELAGSPELLEFLGTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEGPPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAGSPELLEFLGTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEGPPV
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB6 QSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEGLFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEGLFG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 PGRKLSPQDPSEDVSSMDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRDASK
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
XP_016 PGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRDASK
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 ELFRV--EEDLDQILNLGAEPKPKPQLKP-KPPVAAKPVIPRKPAVPPKAGPAEAVAGQQ
::::. .. .. . .:. :.: . .::. .: :
XP_016 ELFRTLAHKGFQCAQSNCLLTSPRIPLQPSRRTTAASSSLPLPPGSWAGVEEEAPLQIQY
280 290 300 310 320 330
370 380 390
pF1KB6 KPQEQIQAMDEMDILQYIQDHDTPAQAAPSLF
XP_016 GESFLRGTQRLPEGSFPLLIVDKGWLLYPIQML
340 350 360
392 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:26:38 2016 done: Sat Nov 5 11:26:40 2016
Total Scan time: 9.160 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]