Result of FASTA (omim) for
pFN21AB6676
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6676, 454 aa
1>>>pF1KB6676 454 - 454 aa - 454 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.6232+/-0.000375; mu= -1.2949+/- 0.024
mean_var=254.6483+/-54.375, 0's: 0 Z-trim(120.4): 32 B-trim: 0 in 0/52
Lambda= 0.080372
statistics sampled from 35653 (35697) to 35653 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.747), E-opt: 0.2 (0.419), width: 16
Scan time: 10.830
The best scores are: opt bits E(85289)
NP_071354 (OMIM: 614968) SH2 domain-containing pro ( 454) 3021 363.4 7.3e-100
NP_001167630 (OMIM: 614968) SH2 domain-containing ( 454) 3021 363.4 7.3e-100
NP_001167631 (OMIM: 614968) SH2 domain-containing ( 409) 2643 319.5 1.1e-86
XP_011542912 (OMIM: 614968) PREDICTED: SH2 domain- ( 427) 1708 211.1 4.7e-54
XP_016869218 (OMIM: 614968) PREDICTED: SH2 domain- ( 427) 1708 211.1 4.7e-54
XP_011526692 (OMIM: 608349) PREDICTED: hematopoiet ( 187) 273 44.4 0.00031
XP_016882892 (OMIM: 608349) PREDICTED: hematopoiet ( 218) 273 44.5 0.00034
XP_016882891 (OMIM: 608349) PREDICTED: hematopoiet ( 225) 273 44.5 0.00035
NP_116244 (OMIM: 608349) hematopoietic SH2 domain- ( 352) 273 44.6 0.0005
XP_016882893 (OMIM: 608349) PREDICTED: hematopoiet ( 176) 249 41.6 0.002
XP_011526688 (OMIM: 608349) PREDICTED: hematopoiet ( 405) 249 41.9 0.0038
>>NP_071354 (OMIM: 614968) SH2 domain-containing protein (454 aa)
initn: 3021 init1: 3021 opt: 3021 Z-score: 1913.8 bits: 363.4 E(85289): 7.3e-100
Smith-Waterman score: 3021; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454)
10 20 30 40 50 60
pF1KB6 MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 ENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 FTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 FTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 QQMLADSINRMKAYAFHQKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 QQMLADSINRMKAYAFHQKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 AADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 AADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 PQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 LLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLV
370 380 390 400 410 420
430 440 450
pF1KB6 EYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE
::::::::::::::::::::::::::::::::::
NP_071 EYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE
430 440 450
>>NP_001167630 (OMIM: 614968) SH2 domain-containing prot (454 aa)
initn: 3021 init1: 3021 opt: 3021 Z-score: 1913.8 bits: 363.4 E(85289): 7.3e-100
Smith-Waterman score: 3021; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454)
10 20 30 40 50 60
pF1KB6 MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 FTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 QQMLADSINRMKAYAFHQKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQMLADSINRMKAYAFHQKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 AADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 LLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLV
370 380 390 400 410 420
430 440 450
pF1KB6 EYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE
::::::::::::::::::::::::::::::::::
NP_001 EYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE
430 440 450
>>NP_001167631 (OMIM: 614968) SH2 domain-containing prot (409 aa)
initn: 2639 init1: 2639 opt: 2643 Z-score: 1677.6 bits: 319.5 E(85289): 1.1e-86
Smith-Waterman score: 2643; 98.5% identity (98.8% similar) in 402 aa overlap (53-454:8-409)
30 40 50 60 70 80
pF1KB6 QKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKKENGKSVHWKLGADKEVWVWVMG
: :. ::::::::::::::::::::::
NP_001 MWRVIEPPCPGAPSTENGKSVHWKLGADKEVWVWVMG
10 20 30
90 100 110 120 130 140
pF1KB6 EHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEEFTNSLKTKSQYHDLQAPDNQQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEEFTNSLKTKSQYHDLQAPDNQQT
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 KDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNIQQMLADSINRMKAYAFHQKKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNIQQMLADSINRMKAYAFHQKKES
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB6 MKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSKAADEKRRSLAKQAREDYKRLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSKAADEKRRSLAKQAREDYKRLSL
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB6 GAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAYPQKPLRNQGVVRTLSSSAQEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAYPQKPLRNQGVVRTLSSSAQEDI
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB6 IRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKGYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKGYA
280 290 300 310 320 330
390 400 410 420 430 440
pF1KB6 LSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQ
340 350 360 370 380 390
450
pF1KB6 QDQLPDYLELFE
::::::::::::
NP_001 QDQLPDYLELFE
400
>>XP_011542912 (OMIM: 614968) PREDICTED: SH2 domain-cont (427 aa)
initn: 1708 init1: 1708 opt: 1708 Z-score: 1091.4 bits: 211.1 E(85289): 4.7e-54
Smith-Waterman score: 2789; 94.1% identity (94.1% similar) in 454 aa overlap (1-454:1-427)
10 20 30 40 50 60
pF1KB6 MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 FTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNI
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIR---------
130 140 150 160 170
190 200 210 220 230 240
pF1KB6 QQMLADSINRMKAYAFHQKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSK
::::::::::::::::::::::::::::::::::::::::::
XP_011 ------------------KKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSK
180 190 200 210
250 260 270 280 290 300
pF1KB6 AADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAY
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 PQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANEL
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB6 LLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLV
340 350 360 370 380 390
430 440 450
pF1KB6 EYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE
::::::::::::::::::::::::::::::::::
XP_011 EYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE
400 410 420
>>XP_016869218 (OMIM: 614968) PREDICTED: SH2 domain-cont (427 aa)
initn: 1708 init1: 1708 opt: 1708 Z-score: 1091.4 bits: 211.1 E(85289): 4.7e-54
Smith-Waterman score: 2789; 94.1% identity (94.1% similar) in 454 aa overlap (1-454:1-427)
10 20 30 40 50 60
pF1KB6 MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 FTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNI
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIR---------
130 140 150 160 170
190 200 210 220 230 240
pF1KB6 QQMLADSINRMKAYAFHQKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSK
::::::::::::::::::::::::::::::::::::::::::
XP_016 ------------------KKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSK
180 190 200 210
250 260 270 280 290 300
pF1KB6 AADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAY
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 PQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANEL
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB6 LLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLV
340 350 360 370 380 390
430 440 450
pF1KB6 EYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE
::::::::::::::::::::::::::::::::::
XP_016 EYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE
400 410 420
>>XP_011526692 (OMIM: 608349) PREDICTED: hematopoietic S (187 aa)
initn: 249 init1: 165 opt: 273 Z-score: 197.1 bits: 44.4 E(85289): 0.00031
Smith-Waterman score: 273; 36.9% identity (63.1% similar) in 130 aa overlap (325-453:17-139)
300 310 320 330 340 350
pF1KB6 LNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTL
:: . :. : ..: . :::: ..
XP_011 MTEAGKLPLPLPPRLDWFVHTQMG-----QLAQDGVPEWFHGAISR
10 20 30 40
360 370 380 390 400 410
pF1KB6 KKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHA
. :..:: : . ::::::::. ::.::: ....: ::.. :. .. ... :.
XP_011 EDAENLLESQPL-GSFLIRVSHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHT
50 60 70 80 90 100
420 430 440 450
pF1KB6 TLADLVEYHKEEPITSLGKELLLYPCGQQDQLP-DYLELFE
.: :: .:...:: .::: :: :.: :: .::
XP_011 SLDALVTFHQQKPIEPR-RELLTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEER
110 120 130 140 150
XP_011 TSQKCSSKSYLLMGLHAPWLPFQSDCEL
160 170 180
>>XP_016882892 (OMIM: 608349) PREDICTED: hematopoietic S (218 aa)
initn: 249 init1: 165 opt: 273 Z-score: 196.2 bits: 44.5 E(85289): 0.00034
Smith-Waterman score: 273; 36.9% identity (63.1% similar) in 130 aa overlap (325-453:17-139)
300 310 320 330 340 350
pF1KB6 LNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTL
:: . :. : ..: . :::: ..
XP_016 MTEAGKLPLPLPPRLDWFVHTQMG-----QLAQDGVPEWFHGAISR
10 20 30 40
360 370 380 390 400 410
pF1KB6 KKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHA
. :..:: : . ::::::::. ::.::: ....: ::.. :. .. ... :.
XP_016 EDAENLLESQPL-GSFLIRVSHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHT
50 60 70 80 90 100
420 430 440 450
pF1KB6 TLADLVEYHKEEPITSLGKELLLYPCGQQDQLP-DYLELFE
.: :: .:...:: .::: :: :.: :: .::
XP_016 SLDALVTFHQQKPIEPR-RELLTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEET
110 120 130 140 150
XP_016 ESCFVDQAGVEWHSLGSLQPPPPRFKRFSCLSLLSSWDYRPPQSQSCVTNQRKGSRQQR
160 170 180 190 200 210
>>XP_016882891 (OMIM: 608349) PREDICTED: hematopoietic S (225 aa)
initn: 249 init1: 165 opt: 273 Z-score: 196.0 bits: 44.5 E(85289): 0.00035
Smith-Waterman score: 273; 36.9% identity (63.1% similar) in 130 aa overlap (325-453:17-139)
300 310 320 330 340 350
pF1KB6 LNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTL
:: . :. : ..: . :::: ..
XP_016 MTEAGKLPLPLPPRLDWFVHTQMG-----QLAQDGVPEWFHGAISR
10 20 30 40
360 370 380 390 400 410
pF1KB6 KKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHA
. :..:: : . ::::::::. ::.::: ....: ::.. :. .. ... :.
XP_016 EDAENLLESQPL-GSFLIRVSHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHT
50 60 70 80 90 100
420 430 440 450
pF1KB6 TLADLVEYHKEEPITSLGKELLLYPCGQQDQLP-DYLELFE
.: :: .:...:: .::: :: :.: :: .::
XP_016 SLDALVTFHQQKPIEPR-RELLTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEET
110 120 130 140 150
XP_016 ESCFVDQAGVEWHSLGSLQPPPPRFKRFSCLSLLSSWDYRCVLIFVFLVETGFHHVGQTG
160 170 180 190 200 210
>>NP_116244 (OMIM: 608349) hematopoietic SH2 domain-cont (352 aa)
initn: 249 init1: 165 opt: 273 Z-score: 193.3 bits: 44.6 E(85289): 0.0005
Smith-Waterman score: 273; 36.9% identity (63.1% similar) in 130 aa overlap (325-453:17-139)
300 310 320 330 340 350
pF1KB6 LNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTL
:: . :. : ..: . :::: ..
NP_116 MTEAGKLPLPLPPRLDWFVHTQMG-----QLAQDGVPEWFHGAISR
10 20 30 40
360 370 380 390 400 410
pF1KB6 KKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHA
. :..:: : . ::::::::. ::.::: ....: ::.. :. .. ... :.
NP_116 EDAENLLESQPL-GSFLIRVSHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHT
50 60 70 80 90 100
420 430 440 450
pF1KB6 TLADLVEYHKEEPITSLGKELLLYPCGQQDQLP-DYLELFE
.: :: .:...:: .::: :: :.: :: .::
NP_116 SLDALVTFHQQKPIEPR-RELLTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEEA
110 120 130 140 150
NP_116 SPKPVLCHQSKERKPSAEMNRITTKEATSSCPPKSPLGETRQKLWRSLKMLPERGQRVRQ
160 170 180 190 200 210
>>XP_016882893 (OMIM: 608349) PREDICTED: hematopoietic S (176 aa)
initn: 238 init1: 165 opt: 249 Z-score: 182.5 bits: 41.6 E(85289): 0.002
Smith-Waterman score: 249; 36.4% identity (63.6% similar) in 121 aa overlap (325-445:17-130)
300 310 320 330 340 350
pF1KB6 LNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTL
:: . :. : : ..: . :::: ..
XP_016 MTEAGKLPLPLPPRLDWFVHTQM----G-QLAQDGVPEWFHGAISR
10 20 30 40
360 370 380 390 400 410
pF1KB6 KKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHA
. :..:: : . ::::::::. ::.::: ....: ::.. :. .. ... :.
XP_016 EDAENLLESQPL-GSFLIRVSHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHT
50 60 70 80 90 100
420 430 440 450
pF1KB6 TLADLVEYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE
.: :: .:...:: .::: :: . :
XP_016 SLDALVTFHQQKPIEPR-RELLTQPCRRIPQTWITRISSSTPTQWPRKLPARCLPLRRPP
110 120 130 140 150
XP_016 QSQSCVTNQRKGSRQQR
160 170
454 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:21:31 2016 done: Sat Nov 5 11:21:32 2016
Total Scan time: 10.830 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]