Result of FASTA (omim) for
pFN21AB5842
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5842, 483 aa
1>>>pF1KB5842 483 - 483 aa - 483 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1347+/-0.000397; mu= 14.2278+/- 0.025
mean_var=75.8665+/-15.389, 0's: 0 Z-trim(112.8): 161 B-trim: 730 in 2/49
Lambda= 0.147248
statistics sampled from 21632 (21815) to 21632 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.606), E-opt: 0.2 (0.256), width: 16
Scan time: 8.660
The best scores are: opt bits E(85289)
NP_004388 (OMIM: 600326) probable ATP-dependent RN ( 483) 3164 681.7 1.2e-195
NP_001244120 (OMIM: 600326) probable ATP-dependent ( 483) 3164 681.7 1.2e-195
XP_005271474 (OMIM: 600326) PREDICTED: probable AT ( 483) 3164 681.7 1.2e-195
XP_016872740 (OMIM: 600326) PREDICTED: probable AT ( 440) 1873 407.4 4.1e-113
XP_011540946 (OMIM: 600326) PREDICTED: probable AT ( 440) 1873 407.4 4.1e-113
XP_011540947 (OMIM: 600326) PREDICTED: probable AT ( 434) 1760 383.4 6.8e-106
NP_055555 (OMIM: 268305,608546) eukaryotic initiat ( 411) 948 210.9 5.4e-54
NP_001407 (OMIM: 602641) eukaryotic initiation fac ( 406) 943 209.9 1.1e-53
NP_001958 (OMIM: 601102) eukaryotic initiation fac ( 407) 930 207.1 7.6e-53
NP_542165 (OMIM: 142560) spliceosome RNA helicase ( 428) 838 187.6 6.1e-47
NP_004631 (OMIM: 142560) spliceosome RNA helicase ( 428) 838 187.6 6.1e-47
NP_057439 (OMIM: 615428) probable ATP-dependent RN ( 455) 744 167.6 6.6e-41
XP_011541093 (OMIM: 607663) PREDICTED: ATP-depende ( 482) 734 165.5 3e-40
NP_037396 (OMIM: 607663) ATP-dependent RNA helicas ( 483) 734 165.5 3e-40
XP_011541092 (OMIM: 607663) PREDICTED: ATP-depende ( 486) 734 165.5 3.1e-40
NP_009173 (OMIM: 605812) ATP-dependent RNA helicas ( 479) 719 162.3 2.8e-39
XP_011521136 (OMIM: 605812) PREDICTED: ATP-depende ( 484) 719 162.3 2.8e-39
XP_011521134 (OMIM: 605812) PREDICTED: ATP-depende ( 539) 719 162.3 3.1e-39
XP_011523824 (OMIM: 268305,608546) PREDICTED: euka ( 390) 699 158.0 4.3e-38
NP_001191439 (OMIM: 602641) eukaryotic initiation ( 347) 697 157.6 5.3e-38
XP_016857920 (OMIM: 174300,615464) PREDICTED: prob ( 619) 686 155.3 4.5e-37
XP_016857921 (OMIM: 174300,615464) PREDICTED: prob ( 619) 686 155.3 4.5e-37
XP_011508337 (OMIM: 174300,615464) PREDICTED: prob ( 619) 686 155.3 4.5e-37
NP_001026895 (OMIM: 174300,615464) probable ATP-de ( 619) 686 155.3 4.5e-37
NP_001317367 (OMIM: 607663) ATP-dependent RNA heli ( 369) 681 154.2 5.9e-37
XP_011534229 (OMIM: 606286) PREDICTED: probable AT ( 529) 683 154.7 6e-37
XP_011534230 (OMIM: 606286) PREDICTED: probable AT ( 529) 683 154.7 6e-37
XP_011534228 (OMIM: 606286) PREDICTED: probable AT ( 604) 683 154.7 6.8e-37
NP_061135 (OMIM: 606286) probable ATP-dependent RN ( 648) 683 154.7 7.3e-37
XP_016866492 (OMIM: 606286) PREDICTED: probable AT ( 439) 679 153.8 9.2e-37
NP_076977 (OMIM: 611665) ATP-dependent RNA helicas ( 881) 681 154.3 1.3e-36
NP_001104792 (OMIM: 611665) ATP-dependent RNA heli ( 882) 681 154.3 1.3e-36
NP_001244102 (OMIM: 605812) ATP-dependent RNA heli ( 370) 671 152.1 2.6e-36
NP_001014449 (OMIM: 605812) ATP-dependent RNA heli ( 370) 671 152.1 2.6e-36
XP_016878379 (OMIM: 605812) PREDICTED: ATP-depende ( 370) 671 152.1 2.6e-36
NP_001244103 (OMIM: 605812) ATP-dependent RNA heli ( 370) 671 152.1 2.6e-36
XP_006721190 (OMIM: 605812) PREDICTED: ATP-depende ( 370) 671 152.1 2.6e-36
NP_004389 (OMIM: 601235) probable ATP-dependent RN ( 875) 667 151.3 1e-35
NP_060365 (OMIM: 616621) probable ATP-dependent RN ( 796) 636 144.7 8.8e-34
XP_016879601 (OMIM: 613369) PREDICTED: ATP-depende ( 775) 621 141.5 7.9e-33
NP_987095 (OMIM: 613369) ATP-dependent RNA helicas ( 938) 621 141.6 9.3e-33
XP_016879600 (OMIM: 613369) PREDICTED: ATP-depende ( 938) 621 141.6 9.3e-33
NP_031398 (OMIM: 613369) ATP-dependent RNA helicas ( 938) 621 141.6 9.3e-33
XP_006721720 (OMIM: 613369) PREDICTED: ATP-depende ( 938) 621 141.6 9.3e-33
NP_001014451 (OMIM: 605812) ATP-dependent RNA heli ( 448) 616 140.4 1e-32
NP_001244101 (OMIM: 605812) ATP-dependent RNA heli ( 453) 616 140.4 1e-32
XP_011521135 (OMIM: 605812) PREDICTED: ATP-depende ( 508) 616 140.4 1.1e-32
NP_001307110 (OMIM: 174300,615464) probable ATP-de ( 567) 610 139.2 3e-32
XP_006711625 (OMIM: 174300,615464) PREDICTED: prob ( 557) 607 138.5 4.6e-32
XP_011522561 (OMIM: 613369) PREDICTED: ATP-depende ( 674) 599 136.8 1.8e-31
>>NP_004388 (OMIM: 600326) probable ATP-dependent RNA he (483 aa)
initn: 3164 init1: 3164 opt: 3164 Z-score: 3633.3 bits: 681.7 E(85289): 1.2e-195
Smith-Waterman score: 3164; 100.0% identity (100.0% similar) in 483 aa overlap (1-483:1-483)
10 20 30 40 50 60
pF1KB5 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
430 440 450 460 470 480
pF1KB5 EKP
:::
NP_004 EKP
>>NP_001244120 (OMIM: 600326) probable ATP-dependent RNA (483 aa)
initn: 3164 init1: 3164 opt: 3164 Z-score: 3633.3 bits: 681.7 E(85289): 1.2e-195
Smith-Waterman score: 3164; 100.0% identity (100.0% similar) in 483 aa overlap (1-483:1-483)
10 20 30 40 50 60
pF1KB5 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
430 440 450 460 470 480
pF1KB5 EKP
:::
NP_001 EKP
>>XP_005271474 (OMIM: 600326) PREDICTED: probable ATP-de (483 aa)
initn: 3164 init1: 3164 opt: 3164 Z-score: 3633.3 bits: 681.7 E(85289): 1.2e-195
Smith-Waterman score: 3164; 100.0% identity (100.0% similar) in 483 aa overlap (1-483:1-483)
10 20 30 40 50 60
pF1KB5 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
430 440 450 460 470 480
pF1KB5 EKP
:::
XP_005 EKP
>>XP_016872740 (OMIM: 600326) PREDICTED: probable ATP-de (440 aa)
initn: 2869 init1: 1867 opt: 1873 Z-score: 2151.8 bits: 407.4 E(85289): 4.1e-113
Smith-Waterman score: 2787; 91.1% identity (91.1% similar) in 483 aa overlap (1-483:1-440)
10 20 30 40 50 60
pF1KB5 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFM------------
250 260 270 280
310 320 330 340 350 360
pF1KB5 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
:::::::::::::::::::::::::::::
XP_016 -------------------------------LQINQSIIFCNSSQRVELLAKKISQLGYS
290 300 310
370 380 390 400 410 420
pF1KB5 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
320 330 340 350 360 370
430 440 450 460 470 480
pF1KB5 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
380 390 400 410 420 430
pF1KB5 EKP
:::
XP_016 EKP
440
>>XP_011540946 (OMIM: 600326) PREDICTED: probable ATP-de (440 aa)
initn: 2869 init1: 1867 opt: 1873 Z-score: 2151.8 bits: 407.4 E(85289): 4.1e-113
Smith-Waterman score: 2787; 91.1% identity (91.1% similar) in 483 aa overlap (1-483:1-440)
10 20 30 40 50 60
pF1KB5 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFM------------
250 260 270 280
310 320 330 340 350 360
pF1KB5 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
:::::::::::::::::::::::::::::
XP_011 -------------------------------LQINQSIIFCNSSQRVELLAKKISQLGYS
290 300 310
370 380 390 400 410 420
pF1KB5 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
320 330 340 350 360 370
430 440 450 460 470 480
pF1KB5 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
380 390 400 410 420 430
pF1KB5 EKP
:::
XP_011 EKP
440
>>XP_011540947 (OMIM: 600326) PREDICTED: probable ATP-de (434 aa)
initn: 1753 init1: 1753 opt: 1760 Z-score: 2022.2 bits: 383.4 E(85289): 6.8e-106
Smith-Waterman score: 2744; 89.9% identity (89.9% similar) in 483 aa overlap (1-483:1-434)
10 20 30 40 50 60
pF1KB5 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQ--------------
130 140 150 160
190 200 210 220 230 240
pF1KB5 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
:::::::::::::::::::::::::
XP_011 -----------------------------------VHVVIATPGRILDLIKKGVAKVDHV
170 180 190
250 260 270 280 290 300
pF1KB5 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB5 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
260 270 280 290 300 310
370 380 390 400 410 420
pF1KB5 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
320 330 340 350 360 370
430 440 450 460 470 480
pF1KB5 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
380 390 400 410 420 430
pF1KB5 EKP
:::
XP_011 EKP
>>NP_055555 (OMIM: 268305,608546) eukaryotic initiation (411 aa)
initn: 865 init1: 372 opt: 948 Z-score: 1090.3 bits: 210.9 E(85289): 5.4e-54
Smith-Waterman score: 948; 36.8% identity (71.7% similar) in 410 aa overlap (63-464:4-407)
40 50 60 70 80
pF1KB5 GGGTQTQQQMNQLKNTNTINNGTQQQAQSMTTTIKPGDDWKKTLKLPPKDL---RIKTS-
:.:. . . .: : : .:. ...::
NP_055 MATTATMATSGSARKRL-LKEEDMTKVEFETSE
10 20 30
90 100 110 120 130 140
pF1KB5 --DVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGK
::: : :. . :...:: ::. .:.:::: ::...: ..:::..:....::::
NP_055 EVDVTPT----FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGK
40 50 60 70 80
150 160 170 180 190 200
pF1KB5 SGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLR
.... : .:. ::.. . ::....::::::.:... . .. .:. .. : ::::.
NP_055 TATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMN-VQCHACIGGTNVG
90 100 110 120 130 140
210 220 230 240 250 260
pF1KB5 DDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILT
.:: .:: ::: .::::..:.:.. .. ..:.::::::..:.. : . . :.
NP_055 EDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRY
150 160 170 180 190 200
270 280 290 300 310 320
pF1KB5 LPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLM-EELTLKGVTQYYAYVT-ERQKVHC
:: :..: :::.: . .. :. . : .: . .::::.:. :... : :. :
NP_055 LPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDT
210 220 230 240 250 260
330 340 350 360 370 380
pF1KB5 LNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGL
: :.. : :.:..::::....:. :..:. . ... .:. : :..:. ....::.:
NP_055 LCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGA
270 280 290 300 310 320
390 400 410 420 430 440
pF1KB5 CRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRF
: :. ::...::.:. :...::.:.:. : :.::::::::.:. :.:::.. ::
NP_055 SRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIR
330 340 350 360 370 380
450 460 470 480
pF1KB5 NLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVEDEKP
:..::. .:.: .: :.
NP_055 ILRDIEQYYSTQIDEMPMNVADLI
390 400 410
>>NP_001407 (OMIM: 602641) eukaryotic initiation factor (406 aa)
initn: 790 init1: 446 opt: 943 Z-score: 1084.6 bits: 209.9 E(85289): 1.1e-53
Smith-Waterman score: 943; 38.7% identity (74.2% similar) in 372 aa overlap (96-464:32-402)
70 80 90 100 110 120
pF1KB5 IKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEE
. :.:. :.. :: ::. .:.:::: ::..
NP_001 SASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQR
10 20 30 40 50 60
130 140 150 160 170 180
pF1KB5 SIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICI
.: ..: :..:.:..::::.... : .:....: ::.:..:::::: :.... .
NP_001 AILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVM
70 80 90 100 110 120
190 200 210 220 230 240
pF1KB5 QVSKHMGGAKVMATTGGTNLRDDIMRLD-DTVHVVIATPGRILDLIKKGVAKVDHVQMIV
.. .:: :. : ::::.: ....:. .. :....::::..:.... . ...:.:
NP_001 ALGDYMG-ASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFV
130 140 150 160 170 180
250 260 270 280 290 300
pF1KB5 LDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLM-EE
:::::..::. : . . ::. : .: :..: :::.: .: . .. .. : .: . ::
NP_001 LDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE
190 200 210 220 230 240
310 320 330 340 350 360
pF1KB5 LTLKGVTQYYAYVT-ERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCF
:::.:. :.: : :. :. : :. : :.:..:: :. ..:. :..:. ..
NP_001 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS
250 260 270 280 290 300
370 380 390 400 410 420
pF1KB5 YIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRI
.:. : :..:. ....::.: : :. :::..::::.: :..:::.:.: :.:.:::
NP_001 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI
310 320 330 340 350 360
430 440 450 460 470 480
pF1KB5 GRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVEDEK
::.::::. :.:::..: .:. .:..:: .: :. .: :.
NP_001 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI
370 380 390 400
pF1KB5 P
>>NP_001958 (OMIM: 601102) eukaryotic initiation factor (407 aa)
initn: 778 init1: 439 opt: 930 Z-score: 1069.7 bits: 207.1 E(85289): 7.6e-53
Smith-Waterman score: 930; 38.4% identity (74.2% similar) in 372 aa overlap (96-464:33-403)
70 80 90 100 110 120
pF1KB5 IKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEE
..:.:. ::. :: ::. .:.:::: ::..
NP_001 GGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQR
10 20 30 40 50 60
130 140 150 160 170 180
pF1KB5 SIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICI
.: ..: :..:.:..::::.... : .:..:... . ::.:..:::::: :.... .
NP_001 AIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVIL
70 80 90 100 110 120
190 200 210 220 230 240
pF1KB5 QVSKHMGGAKVMATTGGTNLRDDIMRLD-DTVHVVIATPGRILDLIKKGVAKVDHVQMIV
.. .:: : : ::::.:.....:. .. :.:..::::..:.... . ..:.:
NP_001 ALGDYMG-ATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFV
130 140 150 160 170 180
250 260 270 280 290 300
pF1KB5 LDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLM-EE
:::::..::. : . . .:. : . :..: :::.: .: . .. .. : .: . ::
NP_001 LDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEE
190 200 210 220 230 240
310 320 330 340 350 360
pF1KB5 LTLKGVTQYYAYVT-ERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCF
:::.:. :.: : :. :. : :. : :.:..:: :. ..:. :..:. ..
NP_001 LTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVS
250 260 270 280 290 300
370 380 390 400 410 420
pF1KB5 YIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRI
.:. : :..:. ....::.: : :. :::..::::.: :..:::.:.: :.:.:::
NP_001 ALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI
310 320 330 340 350 360
430 440 450 460 470 480
pF1KB5 GRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVEDEK
::.::::. :.:::..: .:. :..:: .: .. .: :.
NP_001 GRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI
370 380 390 400
pF1KB5 P
>>NP_542165 (OMIM: 142560) spliceosome RNA helicase DDX3 (428 aa)
initn: 723 init1: 349 opt: 838 Z-score: 963.7 bits: 187.6 E(85289): 6.1e-47
Smith-Waterman score: 838; 34.7% identity (67.8% similar) in 429 aa overlap (49-472:4-426)
20 30 40 50 60 70
pF1KB5 GQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQSMTTTIKPGDDWKKTLKL
: ..: . .. . : :: . :
NP_542 MAENDVDNELLDYEDDEVETAAGGDGAEAPAK-
10 20 30
80 90 100 110 120 130
pF1KB5 PPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILA
:: .: : : : ... :.:. :: ::: .: . :.:.:: .:.: :: :. : :.:
NP_542 --KD--VKGSYV-SIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLC
40 50 60 70 80
140 150 160 170 180 190
pF1KB5 RAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMA
.::.: ::...... :..:. .....:. :::::.:.:. . ::.: ..:: .
NP_542 QAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAV
90 100 110 120 130 140
200 210 220 230 240 250
pF1KB5 TTGGTNLRDDIMRLDDTV-HVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQ-DF
:: ... : : . :.:..:::::: : .. .. :.. ..::: ::.: : :.
NP_542 FFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDM
150 160 170 180 190 200
260 270 280 290 300 310
pF1KB5 VQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEE--LTLKGVTQYYA
. ...:. :...:....:::. .. . .: :.:: . .: :::.:. :::.
NP_542 RRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYV
210 220 230 240 250 260
320 330 340 350 360 370
pF1KB5 YVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRN
. . .: . : :.. :..:: .:: .: :: ::. . . .. . :: : ::.:
NP_542 KLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERL
270 280 290 300 310 320
380 390 400 410 420 430
pF1KB5 RVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLA
...:.. : :: :.:: ::.::. ::...:.:.:. ..:::::..:.:::: :::
NP_542 SRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLA
330 340 350 360 370 380
440 450 460 470 480
pF1KB5 INLIT-YDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVEDEKP
:.... .: :....... ..:. .:..:: : :. .
NP_542 ITFVSDENDAKILNDVQDRFEVNISELPDEIDISSYIEQTR
390 400 410 420
483 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 10:28:47 2016 done: Sat Nov 5 10:28:49 2016
Total Scan time: 8.660 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]