Result of FASTA (ccds) for
pFN21AF0386
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KF0386, 674 aa
1>>>pF1KF0386 674 - 674 aa - 674 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.9882+/-0.0012; mu= -30.8245+/- 0.073
mean_var=735.1097+/-152.164, 0's: 0 Z-trim(117.2): 84 B-trim: 60 in 1/55
Lambda= 0.047304
statistics sampled from 17872 (17947) to 17872 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.797), E-opt: 0.2 (0.551), width: 16
Scan time: 4.970
The best scores are: opt bits E(32554)
CCDS74824.1 MED15 gene_id:51586|Hs108|chr22 ( 677) 4579 327.5 3.8e-89
CCDS77653.1 MED15 gene_id:51586|Hs108|chr22 ( 722) 4081 293.6 6.7e-79
CCDS13781.1 MED15 gene_id:51586|Hs108|chr22 ( 748) 4081 293.6 6.9e-79
CCDS33602.1 MED15 gene_id:51586|Hs108|chr22 ( 788) 2922 214.5 4.7e-55
>>CCDS74824.1 MED15 gene_id:51586|Hs108|chr22 (677 aa)
initn: 3858 init1: 3858 opt: 4579 Z-score: 1714.0 bits: 327.5 E(32554): 3.8e-89
Smith-Waterman score: 4579; 99.6% identity (99.6% similar) in 677 aa overlap (1-674:1-677)
10 20 30 40 50 60
pF1KF0 MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
10 20 30 40 50 60
70 80 90 100 110
pF1KF0 RLIIHFRDIHNKKSQASVSAQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQ--FQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
CCDS74 RLIIHFRDIHNKKSQASVSAQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KF0 QQSAMQQQFQAVVQQQQQLQQQQQQQ-HLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQ
:::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
CCDS74 QQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQ
130 140 150 160 170 180
180 190 200 210 220 230
pF1KF0 QQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 QQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KF0 QNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 QNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQ
250 260 270 280 290 300
300 310 320 330 340 350
pF1KF0 TAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 TAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSS
310 320 330 340 350 360
360 370 380 390 400 410
pF1KF0 GPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 GPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQ
370 380 390 400 410 420
420 430 440 450 460 470
pF1KF0 YLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 YLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIA
430 440 450 460 470 480
480 490 500 510 520 530
pF1KF0 LEKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 LEKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHG
490 500 510 520 530 540
540 550 560 570 580 590
pF1KF0 PPITAPVVCTRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 PPITAPVVCTRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLD
550 560 570 580 590 600
600 610 620 630 640 650
pF1KF0 DKDLPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 DKDLPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTA
610 620 630 640 650 660
660 670
pF1KF0 LLNTWAQSVHQACLSAA
:::::::::::::::::
CCDS74 LLNTWAQSVHQACLSAA
670
>>CCDS77653.1 MED15 gene_id:51586|Hs108|chr22 (722 aa)
initn: 3858 init1: 3858 opt: 4081 Z-score: 1530.0 bits: 293.6 E(32554): 6.7e-79
Smith-Waterman score: 4151; 89.4% identity (89.5% similar) in 706 aa overlap (43-674:17-722)
20 30 40 50 60 70
pF1KF0 TAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNK
::::::::::::::::::::::::::::::
CCDS77 MRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNK
10 20 30 40
pF1KF0 KSQASVS-----------------------------------------------------
:::::::
CCDS77 KSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPG
50 60 70 80 90 100
80 90 100 110
pF1KF0 ------------------AQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQ--FQAQ
.::::::::::::::::::::::::::::::::::: ::::
CCDS77 TSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQ
110 120 130 140 150 160
120 130 140 150 160 170
pF1KF0 QSAMQQQFQAVVQQQQQLQQQQQQQ-HLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQ
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
CCDS77 QSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQ
170 180 190 200 210 220
180 190 200 210 220 230
pF1KF0 QQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 QQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQ
230 240 250 260 270 280
240 250 260 270 280 290
pF1KF0 NQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 NQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQT
290 300 310 320 330 340
300 310 320 330 340 350
pF1KF0 AQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 AQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG
350 360 370 380 390 400
360 370 380 390 400 410
pF1KF0 PAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 PAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQY
410 420 430 440 450 460
420 430 440 450 460 470
pF1KF0 LDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 LDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIAL
470 480 490 500 510 520
480 490 500 510 520 530
pF1KF0 EKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 EKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGP
530 540 550 560 570 580
540 550 560 570 580 590
pF1KF0 PITAPVVCTRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 PITAPVVCTRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDD
590 600 610 620 630 640
600 610 620 630 640 650
pF1KF0 KDLPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 KDLPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTAL
650 660 670 680 690 700
660 670
pF1KF0 LNTWAQSVHQACLSAA
::::::::::::::::
CCDS77 LNTWAQSVHQACLSAA
710 720
>>CCDS13781.1 MED15 gene_id:51586|Hs108|chr22 (748 aa)
initn: 3858 init1: 3858 opt: 4081 Z-score: 1529.7 bits: 293.6 E(32554): 6.9e-79
Smith-Waterman score: 4151; 89.4% identity (89.5% similar) in 706 aa overlap (43-674:43-748)
20 30 40 50 60 70
pF1KF0 TAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNK
::::::::::::::::::::::::::::::
CCDS13 TAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNK
20 30 40 50 60 70
pF1KF0 KSQASVS-----------------------------------------------------
:::::::
CCDS13 KSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPG
80 90 100 110 120 130
80 90 100 110
pF1KF0 ------------------AQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQ--FQAQ
.::::::::::::::::::::::::::::::::::: ::::
CCDS13 TSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQ
140 150 160 170 180 190
120 130 140 150 160 170
pF1KF0 QSAMQQQFQAVVQQQQQLQQQQQQQ-HLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQ
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
CCDS13 QSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQ
200 210 220 230 240 250
180 190 200 210 220 230
pF1KF0 QQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 QQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQ
260 270 280 290 300 310
240 250 260 270 280 290
pF1KF0 NQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 NQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQT
320 330 340 350 360 370
300 310 320 330 340 350
pF1KF0 AQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 AQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG
380 390 400 410 420 430
360 370 380 390 400 410
pF1KF0 PAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 PAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQY
440 450 460 470 480 490
420 430 440 450 460 470
pF1KF0 LDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIAL
500 510 520 530 540 550
480 490 500 510 520 530
pF1KF0 EKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 EKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGP
560 570 580 590 600 610
540 550 560 570 580 590
pF1KF0 PITAPVVCTRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 PITAPVVCTRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDD
620 630 640 650 660 670
600 610 620 630 640 650
pF1KF0 KDLPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 KDLPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTAL
680 690 700 710 720 730
660 670
pF1KF0 LNTWAQSVHQACLSAA
::::::::::::::::
CCDS13 LNTWAQSVHQACLSAA
740
>>CCDS33602.1 MED15 gene_id:51586|Hs108|chr22 (788 aa)
initn: 2710 init1: 2710 opt: 2922 Z-score: 1101.9 bits: 214.5 E(32554): 4.7e-55
Smith-Waterman score: 3991; 92.5% identity (93.0% similar) in 644 aa overlap (74-674:145-788)
50 60 70 80 90 100
pF1KF0 HVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSAQLQLQQVALQQQQQQQQFQQQQQ
: :. ..:::::::::::::::::::::::
CCDS33 SLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQ
120 130 140 150 160 170
110 120 130 140 150 160
pF1KF0 AALQQQQQQQQQ--FQAQQSAMQQQFQAVVQQQQQLQQQQQQQ-HLIKLHHQNQQQIQQQ
:::::::::::: ::::::::::::::::::::::::::::: ::::::::::::::::
CCDS33 AALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQ
180 190 200 210 220 230
170 180 190 200 210 220
pF1KF0 QQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 QQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMH
240 250 260 270 280 290
230 240 250 260 270 280
pF1KF0 HTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 HTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVV
300 310 320 330 340 350
290 300 310
pF1KF0 QQPPVQPQVQQQQTAVQTAQAAQMVAPGVQ------------------------------
::::::::::::::::::::::::::::::
CCDS33 QQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSS
360 370 380 390 400 410
320 330 340 350 360
pF1KF0 ----------VSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPA
::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 IPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPA
420 430 440 450 460 470
370 380 390 400 410 420
pF1KF0 PSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 PSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLD
480 490 500 510 520 530
430 440 450 460 470 480
pF1KF0 KLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 KLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEK
540 550 560 570 580 590
490 500 510 520 530 540
pF1KF0 LKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGPPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGPPI
600 610 620 630 640 650
550 560 570 580 590 600
pF1KF0 TAPVVCTRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDDKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 TAPVVCTRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDDKD
660 670 680 690 700 710
610 620 630 640 650 660
pF1KF0 LPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTALLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTALLN
720 730 740 750 760 770
670
pF1KF0 TWAQSVHQACLSAA
::::::::::::::
CCDS33 TWAQSVHQACLSAA
780
674 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:11:36 2016 done: Fri Nov 4 20:11:37 2016
Total Scan time: 4.970 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]