Result of FASTA (omim) for
pFN21AB9866
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9866, 435 aa
1>>>pF1KB9866 435 - 435 aa - 435 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.8005+/-0.00031; mu= 3.7946+/- 0.020
mean_var=238.2198+/-49.014, 0's: 0 Z-trim(124.1): 51 B-trim: 0 in 0/55
Lambda= 0.083097
statistics sampled from 44984 (45043) to 44984 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.81), E-opt: 0.2 (0.528), width: 16
Scan time: 11.160
The best scores are: opt bits E(85289)
NP_068773 (OMIM: 121015,601885) gap junction alpha ( 435) 2966 368.0 2.7e-101
XP_011533350 (OMIM: 121015,601885) PREDICTED: gap ( 435) 2966 368.0 2.7e-101
NP_005258 (OMIM: 116200,600897,612474) gap junctio ( 433) 1176 153.4 1.1e-36
XP_011507718 (OMIM: 116200,600897,612474) PREDICTE ( 433) 1176 153.4 1.1e-36
XP_011507719 (OMIM: 116200,600897,612474) PREDICTE ( 427) 1158 151.2 4.7e-36
XP_005273008 (OMIM: 108770,121013,612474,614049) P ( 358) 1023 135.0 3.1e-31
XP_016856533 (OMIM: 108770,121013,612474,614049) P ( 358) 1023 135.0 3.1e-31
NP_859054 (OMIM: 108770,121013,612474,614049) gap ( 358) 1023 135.0 3.1e-31
NP_005257 (OMIM: 108770,121013,612474,614049) gap ( 358) 1023 135.0 3.1e-31
XP_005270807 (OMIM: 121012) PREDICTED: gap junctio ( 333) 989 130.9 4.9e-30
NP_002051 (OMIM: 121012) gap junction alpha-4 prot ( 333) 989 130.9 4.9e-30
XP_016856532 (OMIM: 121012) PREDICTED: gap junctio ( 333) 989 130.9 4.9e-30
NP_115991 (OMIM: 611924) gap junction alpha-10 pro ( 543) 955 127.0 1.2e-28
NP_110399 (OMIM: 611923) gap junction alpha-9 prot ( 515) 949 126.3 1.9e-28
NP_000156 (OMIM: 104100,121014,133200,164200,18610 ( 382) 942 125.3 2.7e-28
NP_699199 (OMIM: 611922) gap junction delta-4 prot ( 370) 534 76.4 1.4e-13
NP_003995 (OMIM: 121011,124500,148210,148350,14920 ( 226) 477 69.3 1.1e-11
XP_011533351 (OMIM: 121011,124500,148210,148350,14 ( 226) 477 69.3 1.1e-11
NP_065168 (OMIM: 608803,608804,613206,613480) gap ( 439) 471 68.9 3e-11
XP_016875849 (OMIM: 129500,220290,304400,604418,61 ( 261) 466 68.1 3.1e-11
NP_001103690 (OMIM: 129500,220290,304400,604418,61 ( 261) 466 68.1 3.1e-11
NP_006774 (OMIM: 129500,220290,304400,604418,61264 ( 261) 466 68.1 3.1e-11
NP_001103689 (OMIM: 129500,220290,304400,604418,61 ( 261) 466 68.1 3.1e-11
XP_016875847 (OMIM: 129500,220290,304400,604418,61 ( 261) 466 68.1 3.1e-11
XP_016875848 (OMIM: 129500,220290,304400,604418,61 ( 261) 466 68.1 3.1e-11
XP_016875846 (OMIM: 129500,220290,304400,604418,61 ( 261) 466 68.1 3.1e-11
NP_001103691 (OMIM: 129500,220290,304400,604418,61 ( 261) 466 68.1 3.1e-11
XP_005256978 (OMIM: 608655) PREDICTED: gap junctio ( 396) 462 67.8 5.8e-11
XP_005256977 (OMIM: 608655) PREDICTED: gap junctio ( 396) 462 67.8 5.8e-11
NP_005488 (OMIM: 608655) gap junction gamma-1 prot ( 396) 462 67.8 5.8e-11
NP_001073852 (OMIM: 608655) gap junction gamma-1 p ( 396) 462 67.8 5.8e-11
NP_000157 (OMIM: 302800,304040) gap junction beta- ( 283) 447 65.8 1.6e-10
XP_011529209 (OMIM: 302800,304040) PREDICTED: gap ( 283) 447 65.8 1.6e-10
XP_016884897 (OMIM: 302800,304040) PREDICTED: gap ( 283) 447 65.8 1.6e-10
NP_001091111 (OMIM: 302800,304040) gap junction be ( 283) 447 65.8 1.6e-10
NP_694944 (OMIM: 133200,605425) gap junction beta- ( 266) 446 65.7 1.7e-10
XP_011538981 (OMIM: 133200,605425) PREDICTED: gap ( 266) 446 65.7 1.7e-10
NP_001005752 (OMIM: 133200,220290,603324,612644) g ( 270) 443 65.3 2.1e-10
NP_076872 (OMIM: 133200,220290,603324,612644) gap ( 270) 443 65.3 2.1e-10
NP_689343 (OMIM: 607425) gap junction delta-3 prot ( 294) 426 63.3 9.4e-10
NP_065711 (OMIM: 607058) gap junction delta-2 prot ( 321) 422 62.9 1.4e-09
NP_005259 (OMIM: 604493) gap junction beta-5 prote ( 273) 406 60.9 4.7e-09
XP_005270808 (OMIM: 604493) PREDICTED: gap junctio ( 273) 406 60.9 4.7e-09
XP_005248773 (OMIM: 611921) PREDICTED: gap junctio ( 223) 399 60.0 7.2e-09
NP_940970 (OMIM: 611921) gap junction beta-7 prote ( 223) 399 60.0 7.2e-09
XP_016877927 (OMIM: 607058) PREDICTED: gap junctio ( 270) 385 58.4 2.7e-08
NP_853516 (OMIM: 611925) gap junction gamma-3 prot ( 279) 346 53.7 6.9e-07
>>NP_068773 (OMIM: 121015,601885) gap junction alpha-3 p (435 aa)
initn: 2966 init1: 2966 opt: 2966 Z-score: 1939.6 bits: 368.0 E(85289): 2.7e-101
Smith-Waterman score: 2966; 99.8% identity (100.0% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 SPKEPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKPLYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 SPKEPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKPLYR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 CDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSRLGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 CDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSRLGP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 DASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADFKML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
NP_068 DASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADFKLL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQPPALKAYPAASTPAAPSPVGSSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 ALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQPPALKAYPAASTPAAPSPVGSSSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 PLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQPPLPLGDPGRASKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 PLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQPPLPLGDPGRASKA
370 380 390 400 410 420
430
pF1KB9 SRASSGRARPEDLAI
:::::::::::::::
NP_068 SRASSGRARPEDLAI
430
>>XP_011533350 (OMIM: 121015,601885) PREDICTED: gap junc (435 aa)
initn: 2966 init1: 2966 opt: 2966 Z-score: 1939.6 bits: 368.0 E(85289): 2.7e-101
Smith-Waterman score: 2966; 99.8% identity (100.0% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 SPKEPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKPLYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPKEPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKPLYR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 CDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSRLGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSRLGP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 DASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADFKML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_011 DASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADFKLL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQPPALKAYPAASTPAAPSPVGSSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQPPALKAYPAASTPAAPSPVGSSSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 PLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQPPLPLGDPGRASKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQPPLPLGDPGRASKA
370 380 390 400 410 420
430
pF1KB9 SRASSGRARPEDLAI
:::::::::::::::
XP_011 SRASSGRARPEDLAI
430
>>NP_005258 (OMIM: 116200,600897,612474) gap junction al (433 aa)
initn: 1171 init1: 657 opt: 1176 Z-score: 779.8 bits: 153.4 E(85289): 1.1e-36
Smith-Waterman score: 1176; 45.5% identity (66.4% similar) in 446 aa overlap (1-435:1-433)
10 20 30 40 50 60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
:::::::: .::...:::::::.::::::::::::.::.::: :::::::::.:::::::
NP_005 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
:::::::.::::::::.:.:::::::::.:.:.::..: ::::::.: :: :: : ...
NP_005 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEE-LGQQAG
70 80 90 100 110
130 140 150 160 170
pF1KB9 SPKEPPQDN-PSSRDDRG--RVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKP
. : : . .: ..: . :. :.:::::. .::::::::::::.:.::::::.. :
NP_005 TNGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 LYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSR
::::.::::::.::::.::::::::::.:::.:: .::.::..:. ::: : .....
NP_005 LYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 LGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADF
. .: : . . .. . . . :: .. : .: :: :
NP_005 VEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMV--ETSPLPAKPF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 KMLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQ-PPALKAYPAASTPAAPSPVG
... : . : . : :... : . . . : .: . ::: .. . : .
NP_005 NQFE--EKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEG----AEPEVGEKKE
300 310 320 330 340 350
360 370 380 390 400
pF1KB9 SSSPPLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQ-------PPL
. ..: : :.: .: : : :: .. .. . : :
NP_005 EAERLTTEEQEKVAVP---EGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPEL
360 370 380 390 400
410 420 430
pF1KB9 PLGDPGRASKASRASSGRARPEDLAI
: :. :.::: ::: .::..
NP_005 TTDDARPLSRLSKASS-RARSDDLTV
410 420 430
>>XP_011507718 (OMIM: 116200,600897,612474) PREDICTED: g (433 aa)
initn: 1171 init1: 657 opt: 1176 Z-score: 779.8 bits: 153.4 E(85289): 1.1e-36
Smith-Waterman score: 1176; 45.5% identity (66.4% similar) in 446 aa overlap (1-435:1-433)
10 20 30 40 50 60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
:::::::: .::...:::::::.::::::::::::.::.::: :::::::::.:::::::
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
:::::::.::::::::.:.:::::::::.:.:.::..: ::::::.: :: :: : ...
XP_011 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEE-LGQQAG
70 80 90 100 110
130 140 150 160 170
pF1KB9 SPKEPPQDN-PSSRDDRG--RVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKP
. : : . .: ..: . :. :.:::::. .::::::::::::.:.::::::.. :
XP_011 TNGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 LYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSR
::::.::::::.::::.::::::::::.:::.:: .::.::..:. ::: : .....
XP_011 LYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 LGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADF
. .: : . . .. . . . :: .. : .: :: :
XP_011 VEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMV--ETSPLPAKPF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 KMLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQ-PPALKAYPAASTPAAPSPVG
... : . : . : :... : . . . : .: . ::: .. . : .
XP_011 NQFE--EKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEG----AEPEVGEKKE
300 310 320 330 340 350
360 370 380 390 400
pF1KB9 SSSPPLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQ-------PPL
. ..: : :.: .: : : :: .. .. . : :
XP_011 EAERLTTEEQEKVAVP---EGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPEL
360 370 380 390 400
410 420 430
pF1KB9 PLGDPGRASKASRASSGRARPEDLAI
: :. :.::: ::: .::..
XP_011 TTDDARPLSRLSKASS-RARSDDLTV
410 420 430
>>XP_011507719 (OMIM: 116200,600897,612474) PREDICTED: g (427 aa)
initn: 1148 init1: 657 opt: 1158 Z-score: 768.3 bits: 151.2 E(85289): 4.7e-36
Smith-Waterman score: 1158; 45.7% identity (66.1% similar) in 440 aa overlap (1-429:1-427)
10 20 30 40 50 60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
:::::::: .::...:::::::.::::::::::::.::.::: :::::::::.:::::::
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
:::::::.::::::::.:.:::::::::.:.:.::..: ::::::.: :: :: : ...
XP_011 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEE-LGQQAG
70 80 90 100 110
130 140 150 160 170
pF1KB9 SPKEPPQDN-PSSRDDRG--RVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKP
. : : . .: ..: . :. :.:::::. .::::::::::::.:.::::::.. :
XP_011 TNGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 LYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSR
::::.::::::.::::.::::::::::.:::.:: .::.::..:. ::: : .....
XP_011 LYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 LGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADF
. .: : . . .. . . . :: .. : .: :: :
XP_011 VEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMV--ETSPLPAKPF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 KMLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQ-PPALKAYPAASTPAAPSPVG
... : . : . : :... : . . . : .: . ::: .. . : .
XP_011 NQFE--EKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEG----AEPEVGEKKE
300 310 320 330 340 350
360 370 380 390 400
pF1KB9 SSSPPLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQ-------PPL
. ..: : :.: .: : : :: .. .. . : :
XP_011 EAERLTTEEQEKVAVP---EGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPEL
360 370 380 390 400
410 420 430
pF1KB9 PLGDPGRASKASRASSGRARPEDLAI
: :. :.::: :::
XP_011 TTDDARPLSRLSKASS-RAR
410 420
>>XP_005273008 (OMIM: 108770,121013,612474,614049) PREDI (358 aa)
initn: 1032 init1: 627 opt: 1023 Z-score: 681.8 bits: 135.0 E(85289): 3.1e-31
Smith-Waterman score: 1023; 61.0% identity (83.5% similar) in 236 aa overlap (1-232:1-236)
10 20 30 40 50 60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
:::::::: .::....::::.::::::::::::.::::.:::. :::::.:: :.: :::
XP_005 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
10 20 30 40 50 60
70 80 90 100 110
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLK-RES
:.:::::.::::::::.:.:::::::::.:.:.::..: :::.::.: :: :. . : :
XP_005 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 PSPKEPPQDNPSS---RDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELK
: . : .. .. ::. . :.:: ::: .:...: .:::::.::::.::. :
XP_005 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 PLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTS
:. : : :::. :.:..::::::..::.:::::: ::::.. :.:::::::..:
XP_005 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 RLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAAD
XP_005 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
250 260 270 280 290 300
>>XP_016856533 (OMIM: 108770,121013,612474,614049) PREDI (358 aa)
initn: 1032 init1: 627 opt: 1023 Z-score: 681.8 bits: 135.0 E(85289): 3.1e-31
Smith-Waterman score: 1023; 61.0% identity (83.5% similar) in 236 aa overlap (1-232:1-236)
10 20 30 40 50 60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
:::::::: .::....::::.::::::::::::.::::.:::. :::::.:: :.: :::
XP_016 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
10 20 30 40 50 60
70 80 90 100 110
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLK-RES
:.:::::.::::::::.:.:::::::::.:.:.::..: :::.::.: :: :. . : :
XP_016 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 PSPKEPPQDNPSS---RDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELK
: . : .. .. ::. . :.:: ::: .:...: .:::::.::::.::. :
XP_016 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 PLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTS
:. : : :::. :.:..::::::..::.:::::: ::::.. :.:::::::..:
XP_016 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 RLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAAD
XP_016 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
250 260 270 280 290 300
>>NP_859054 (OMIM: 108770,121013,612474,614049) gap junc (358 aa)
initn: 1032 init1: 627 opt: 1023 Z-score: 681.8 bits: 135.0 E(85289): 3.1e-31
Smith-Waterman score: 1023; 61.0% identity (83.5% similar) in 236 aa overlap (1-232:1-236)
10 20 30 40 50 60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
:::::::: .::....::::.::::::::::::.::::.:::. :::::.:: :.: :::
NP_859 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
10 20 30 40 50 60
70 80 90 100 110
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLK-RES
:.:::::.::::::::.:.:::::::::.:.:.::..: :::.::.: :: :. . : :
NP_859 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 PSPKEPPQDNPSS---RDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELK
: . : .. .. ::. . :.:: ::: .:...: .:::::.::::.::. :
NP_859 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 PLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTS
:. : : :::. :.:..::::::..::.:::::: ::::.. :.:::::::..:
NP_859 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 RLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAAD
NP_859 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
250 260 270 280 290 300
>>NP_005257 (OMIM: 108770,121013,612474,614049) gap junc (358 aa)
initn: 1032 init1: 627 opt: 1023 Z-score: 681.8 bits: 135.0 E(85289): 3.1e-31
Smith-Waterman score: 1023; 61.0% identity (83.5% similar) in 236 aa overlap (1-232:1-236)
10 20 30 40 50 60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
:::::::: .::....::::.::::::::::::.::::.:::. :::::.:: :.: :::
NP_005 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
10 20 30 40 50 60
70 80 90 100 110
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLK-RES
:.:::::.::::::::.:.:::::::::.:.:.::..: :::.::.: :: :. . : :
NP_005 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 PSPKEPPQDNPSS---RDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELK
: . : .. .. ::. . :.:: ::: .:...: .:::::.::::.::. :
NP_005 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 PLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTS
:. : : :::. :.:..::::::..::.:::::: ::::.. :.:::::::..:
NP_005 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 RLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAAD
NP_005 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
250 260 270 280 290 300
>>XP_005270807 (OMIM: 121012) PREDICTED: gap junction al (333 aa)
initn: 1070 init1: 603 opt: 989 Z-score: 660.2 bits: 130.9 E(85289): 4.9e-30
Smith-Waterman score: 1018; 46.6% identity (66.6% similar) in 371 aa overlap (1-359:1-328)
10 20 30 40 50 60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
::::.:: .::...::::::.::.:::::::::::.:: :.:.::::::::: ::: :::
XP_005 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
10 20 30 40 50 60
70 80 90 100 110
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEE-EQLKRES
: :::::.::::::::.:.::..:::::::.:::::... : ::. ...: : . : ..
XP_005 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 PSPKEP-----PQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFE
:. .. : : . ::.:. :::. ::: ... :...:.::. ::. :::.
XP_005 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 LKPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGV
..:.. :.: ::: ::::.::::::::::::::.:. ::.::.::. :: . :..:.
XP_005 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 TSRLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPA
.: : :: :: :: : . . : : :.::. :..::
XP_005 RARQGQDA---------PPTQGTSSDPYTDQVFF--YL-----PVGQG-----PSSPP--
250 260 270
300 310 320 330 340
pF1KB9 ADFKMLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQ-----PPALKAYPAASTP
::: : .:::::: ..:.. :: . : .
XP_005 -----------------CPTYNG---LSSSEQNWANLTTEERLASSRPPLFLDPPPQNGQ
280 290 300 310
350 360 370 380 390 400
pF1KB9 AAPS-PVGSSSPPLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQPP
:: : .:.:
XP_005 KPPSRPSSSASKKQYV
320 330
435 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 19:52:18 2016 done: Fri Nov 4 19:52:20 2016
Total Scan time: 11.160 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]