Result of FASTA (omim) for
pFN21AB9854
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9854, 389 aa
1>>>pF1KB9854 389 - 389 aa - 389 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8219+/-0.00036; mu= 20.2939+/- 0.023
mean_var=66.8575+/-13.243, 0's: 0 Z-trim(113.2): 9 B-trim: 0 in 0/51
Lambda= 0.156855
statistics sampled from 22431 (22435) to 22431 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.263), width: 16
Scan time: 8.320
The best scores are: opt bits E(85289)
NP_001164045 (OMIM: 300976) protein FAM46D [Homo s ( 389) 2616 600.9 1.7e-171
NP_689843 (OMIM: 300976) protein FAM46D [Homo sapi ( 389) 2616 600.9 1.7e-171
NP_060103 (OMIM: 611357) protein FAM46A [Homo sapi ( 442) 1544 358.3 2e-98
NP_060179 (OMIM: 613952) protein FAM46C [Homo sapi ( 391) 1502 348.8 1.3e-95
>>NP_001164045 (OMIM: 300976) protein FAM46D [Homo sapie (389 aa)
initn: 2616 init1: 2616 opt: 2616 Z-score: 3199.8 bits: 600.9 E(85289): 1.7e-171
Smith-Waterman score: 2616; 99.7% identity (100.0% similar) in 389 aa overlap (1-389:1-389)
10 20 30 40 50 60
pF1KB9 MSEIRFTNLTWDQVITLDQVLDEVIPIHGKGNFPTMEVKPKDIIHVVKDQLIGQGIIVKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSEIRFTNLTWDQVITLDQVLDEVIPIHGKGNFPTMEVKPKDIIHVVKDQLIGQGIIVKD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 ARLNGSVASYILASHNGISYKDLDVIFGVELPGNEEFQVVKDAVLDCLLDFLPKDVKKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARLNGSVASYILASHNGISYKDLDVIFGVELPGNEEFQVVKDAVLDCLLDFLPKDVKKEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 LSPDIMKDAYVQKLVKVCNGHDCWSLISLSNNTGKNLELKFVSSLRRQFEFSVDSFQIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSPDIMKDAYVQKLVKVCNGHDCWSLISLSNNTGKNLELKFVSSLRRQFEFSVDSFQIVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DPMLEFYSDKNAKLTKESYPVVVAESMYGDFQEAMTHLQHKLICTRKPEEIRGGGLLKYC
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPMLDFYSDKNAKLTKESYPVVVAESMYGDFQEAMTHLQHKLICTRKPEEIRGGGLLKYC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 SLLVHGFKPACMSEIKNLERYMCSRFFIDFPHIEEQQKKIESYLHNHFIGEGMTKYDYLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLLVHGFKPACMSEIKNLERYMCSRFFIDFPHIEEQQKKIESYLHNHFIGEGMTKYDYLM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 TLHGVVNESTVCLMSYERRQILHLITMMALKVLGELNILPNTQKVTCFYQPAPYFAAEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLHGVVNESTVCLMSYERRQILHLITMMALKVLGELNILPNTQKVTCFYQPAPYFAAEAR
310 320 330 340 350 360
370 380
pF1KB9 YPIYVIPEPPPVSFQPYHPLHFRGSNGMS
:::::::::::::::::::::::::::::
NP_001 YPIYVIPEPPPVSFQPYHPLHFRGSNGMS
370 380
>>NP_689843 (OMIM: 300976) protein FAM46D [Homo sapiens] (389 aa)
initn: 2616 init1: 2616 opt: 2616 Z-score: 3199.8 bits: 600.9 E(85289): 1.7e-171
Smith-Waterman score: 2616; 99.7% identity (100.0% similar) in 389 aa overlap (1-389:1-389)
10 20 30 40 50 60
pF1KB9 MSEIRFTNLTWDQVITLDQVLDEVIPIHGKGNFPTMEVKPKDIIHVVKDQLIGQGIIVKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 MSEIRFTNLTWDQVITLDQVLDEVIPIHGKGNFPTMEVKPKDIIHVVKDQLIGQGIIVKD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 ARLNGSVASYILASHNGISYKDLDVIFGVELPGNEEFQVVKDAVLDCLLDFLPKDVKKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 ARLNGSVASYILASHNGISYKDLDVIFGVELPGNEEFQVVKDAVLDCLLDFLPKDVKKEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 LSPDIMKDAYVQKLVKVCNGHDCWSLISLSNNTGKNLELKFVSSLRRQFEFSVDSFQIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LSPDIMKDAYVQKLVKVCNGHDCWSLISLSNNTGKNLELKFVSSLRRQFEFSVDSFQIVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DPMLEFYSDKNAKLTKESYPVVVAESMYGDFQEAMTHLQHKLICTRKPEEIRGGGLLKYC
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 DPMLDFYSDKNAKLTKESYPVVVAESMYGDFQEAMTHLQHKLICTRKPEEIRGGGLLKYC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 SLLVHGFKPACMSEIKNLERYMCSRFFIDFPHIEEQQKKIESYLHNHFIGEGMTKYDYLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 SLLVHGFKPACMSEIKNLERYMCSRFFIDFPHIEEQQKKIESYLHNHFIGEGMTKYDYLM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 TLHGVVNESTVCLMSYERRQILHLITMMALKVLGELNILPNTQKVTCFYQPAPYFAAEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 TLHGVVNESTVCLMSYERRQILHLITMMALKVLGELNILPNTQKVTCFYQPAPYFAAEAR
310 320 330 340 350 360
370 380
pF1KB9 YPIYVIPEPPPVSFQPYHPLHFRGSNGMS
:::::::::::::::::::::::::::::
NP_689 YPIYVIPEPPPVSFQPYHPLHFRGSNGMS
370 380
>>NP_060103 (OMIM: 611357) protein FAM46A [Homo sapiens] (442 aa)
initn: 1524 init1: 1034 opt: 1544 Z-score: 1888.0 bits: 358.3 E(85289): 2e-98
Smith-Waterman score: 1544; 62.9% identity (85.7% similar) in 364 aa overlap (9-372:66-427)
10 20 30
pF1KB9 MSEIRFTNLTWDQVITLDQVLDEVIPIHGKGNFPTMEV
:.:.:: :: .:.:.:::::.:::::.:.
NP_060 DFGGGDFGGGGSFGGHCLDYCESPTAHCNVLNWEQVQRLDGILSETIPIHGRGNFPTLEL
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB9 KPKDIIHVVKDQLIGQGIIVKDARLNGSVASYILASHNGISYKDLDVIFGVELPGNEEFQ
.:. :..::. .: . : :.:.:::::.::..: . .:..:::::.:: ..: :. :::
NP_060 QPSLIVKVVRRRLAEKRIGVRDVRLNGSAASHVLHQDSGLGYKDLDLIFCADLRGEGEFQ
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB9 VVKDAVLDCLLDFLPKDVKKEKLSPDIMKDAYVQKLVKVCNGHDCWSLISLSNNTGKNLE
.:::.::::::::::. :.:::..: .:.:::::.::::: : :::::::::.:::.:
NP_060 TVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKVCNDSDRWSLISLSNNSGKNVE
160 170 180 190 200 210
160 170 180 190 200 210
pF1KB9 LKFVSSLRRQFEFSVDSFQIVLDPMLEFYSDKNAKLTKESYPVVVAESMYGDFQEAMTHL
::::.::::::::::::::: :: .: :: .. .:. .:....::.:::::::. ::
NP_060 LKFVDSLRRQFEFSVDSFQIKLDSLLLFYECSENPMTETFHPTIIGESVYGDFQEAFDHL
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB9 QHKLICTRKPEEIRGGGLLKYCSLLVHGFKPACMSEIKNLERYMCSRFFIDFPHIEEQQK
.:.: ::.:::::::::::::.:::.::.:: .:::.:.::::::::::: : :::.
NP_060 CNKIIATRNPEEIRGGGLLKYCNLLVRGFRPAS-DEIKTLQRYMCSRFFIDFSDIGEQQR
280 290 300 310 320 330
280 290 300 310 320 330
pF1KB9 KIESYLHNHFIGEGMTKYDYLMTLHGVVNESTVCLMSYERRQILHLITMMALKVLGELNI
:.::::.:::.: ::.:::::::::::::::::..:::: :.::::.:..::.. :.
NP_060 KLESYLQNHFVGLEDRKYEYLMTLHGVVNESTVCLMGHERRQTLNLITMLAIRVLADQNV
340 350 360 370 380 390
340 350 360 370 380
pF1KB9 LPNTQKVTCFYQPAPYFAAEARYPIYVIPEPPPVSFQPYHPLHFRGSNGMS
.::. .:::.:::::: .:.: . : : . ::
NP_060 IPNVANVTCYYQPAPY-VADANFSNYYIAQVQPVFTCQQQTYSTWLPCN
400 410 420 430 440
>>NP_060179 (OMIM: 613952) protein FAM46C [Homo sapiens] (391 aa)
initn: 1490 init1: 1465 opt: 1502 Z-score: 1837.3 bits: 348.8 E(85289): 1.3e-95
Smith-Waterman score: 1502; 59.6% identity (84.2% similar) in 374 aa overlap (4-377:12-384)
10 20 30 40 50
pF1KB9 MSEIRFTNLTWDQVITLDQVLDEVIPIHGKGNFPTMEVKPKDIIHVVKDQLI
. :. :.:::: : .:: ::.::::.:::::.:. :::...:...:
NP_060 MAEESSCTRDCMSFSVLNWDQVSRLHEVLTEVVPIHGRGNFPTLEITLKDIVQTVRSRLE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 GQGIIVKDARLNGSVASYILASHNGISYKDLDVIFGVELPGNEEFQVVKDAVLDCLLDFL
:: :.:.:::::.:...:.. ::.. ::::.:: : :: . :::.:.:.:: ::.::
NP_060 EAGIKVHDVRLNGSAAGHVLVKDNGLGCKDLDLIFHVALPTEAEFQLVRDVVLCSLLNFL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 PKDVKKEKLSPDIMKDAYVQKLVKVCNGHDCWSLISLSNNTGKNLELKFVSSLRRQFEFS
:. :.: :.:: .:.::::::::::. : ::::::::..:::.:::::.:.:::::::
NP_060 PEGVNKLKISPVTLKEAYVQKLVKVCTDTDRWSLISLSNKNGKNVELKFVDSIRRQFEFS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 VDSFQIVLDPMLEFYSDKNAKLTKESYPVVVAESMYGDFQEAMTHLQHKLICTRKPEEIR
::::::.:: .: ::. .: .... .:.:..:::::::.::. :::..:: :..:::::
NP_060 VDSFQIILDSLLFFYDCSNNPISEHFHPTVIGESMYGDFEEAFDHLQNRLIATKNPEEIR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 GGGLLKYCSLLVHGFKPACMSEIKNLERYMCSRFFIDFPHIEEQQKKIESYLHNHFIGEG
::::::: .:::. :.:. . :::.:::::::::::::: : :::.:.:.::.::: :
NP_060 GGGLLKYSNLLVRDFRPTDQEEIKTLERYMCSRFFIDFPDILEQQRKLETYLQNHFAEEE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB9 MTKYDYLMTLHGVVNESTVCLMSYERRQILHLITMMALKVLGELNILPNTQKVTCFYQPA
.:::::: :. ::::::::::..:::: :.::...::.::.: ::.:.. .:::.::::
NP_060 RSKYDYLMILRRVVNESTVCLMGHERRQTLNLISLLALRVLAEQNIIPSATNVTCYYQPA
310 320 330 340 350 360
360 370 380
pF1KB9 PYFAAEARYPIYVIPEPPPVSFQPYHPLHFRGSNGMS
:: .... . : . .:: . :::
NP_060 PY-VSDGNFSNYYVAHPPVTYSQPYPTWLPCN
370 380 390
389 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 19:48:10 2016 done: Fri Nov 4 19:48:11 2016
Total Scan time: 8.320 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]