Result of FASTA (ccds) for
pFN21AB9824
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9824, 315 aa
1>>>pF1KB9824 315 - 315 aa - 315 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.9752+/-0.000781; mu= 5.5556+/- 0.048
mean_var=175.3239+/-33.809, 0's: 0 Z-trim(115.7): 20 B-trim: 48 in 1/50
Lambda= 0.096862
statistics sampled from 16202 (16219) to 16202 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.815), E-opt: 0.2 (0.498), width: 16
Scan time: 3.020
The best scores are: opt bits E(32554)
CCDS9463.1 SPRY2 gene_id:10253|Hs108|chr13 ( 315) 2291 331.4 5.6e-91
CCDS3731.1 SPRY1 gene_id:10252|Hs108|chr4 ( 319) 1131 169.3 3.5e-42
CCDS14769.4 SPRY3 gene_id:10251|Hs108|chrY ( 288) 885 134.9 7.3e-32
CCDS14769.4 SPRY3 gene_id:10251|Hs108|chrX ( 288) 885 134.9 7.3e-32
CCDS47296.1 SPRY4 gene_id:81848|Hs108|chr5 ( 299) 830 127.2 1.5e-29
CCDS4274.1 SPRY4 gene_id:81848|Hs108|chr5 ( 322) 830 127.2 1.6e-29
>>CCDS9463.1 SPRY2 gene_id:10253|Hs108|chr13 (315 aa)
initn: 2291 init1: 2291 opt: 2291 Z-score: 1746.8 bits: 331.4 E(32554): 5.6e-91
Smith-Waterman score: 2291; 100.0% identity (100.0% similar) in 315 aa overlap (1-315:1-315)
10 20 30 40 50 60
pF1KB9 MEARAQSGNGSQPLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 MEARAQSGNGSQPLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 VVPRPGLKPAPRPSTQHKHERLHGLPEHRQPPRLQHSQVHSSARAPLSRSISTVSSGSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 VVPRPGLKPAPRPSTQHKHERLHGLPEHRQPPRLQHSQVHSSARAPLSRSISTVSSGSRS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 STRTSTSSSSSEQRLLGSSFSSGPVADGIIRVQPKSELKPGELKPLSKEDLGLHAYRCED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 STRTSTSSSSSEQRLLGSSFSSGPVADGIIRVQPKSELKPGELKPLSKEDLGLHAYRCED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 CGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSNDDEDNCADN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 CGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSNDDEDNCADN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 PCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCKNSNTVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS94 PCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCKNSNTVC
250 260 270 280 290 300
310
pF1KB9 CKVPTVPPRNFEKPT
:::::::::::::::
CCDS94 CKVPTVPPRNFEKPT
310
>>CCDS3731.1 SPRY1 gene_id:10252|Hs108|chr4 (319 aa)
initn: 1013 init1: 461 opt: 1131 Z-score: 870.7 bits: 169.3 E(32554): 3.5e-42
Smith-Waterman score: 1152; 55.2% identity (73.0% similar) in 330 aa overlap (1-315:1-319)
10 20 30 40 50
pF1KB9 MEARAQSGNGSQ-PLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGP
:. . : :.::. ..: : .::: . . :. : . .::::::.:::..:::::::
CCDS37 MDPQNQHGSGSSLVVIQQPSLDSRQRLDYE-RE--IQPTAILSLDQIKAIRGSNEYTEGP
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 TVVPRPGLKPAPRPSTQHKHERLHGL-P-------EHRQPPRLQHSQVHSSARAP-LSRS
.:: ::. . ::: :.:::: : . : :::. .: :. . :.::.: ::::
CCDS37 SVVKRPAPRTAPR---QEKHERTHEIIPINVNNNYEHRHTSHLGHAVLPSNARGPILSRS
60 70 80 90 100 110
120 130 140 150 160
pF1KB9 ISTVSSGSRSSTRTSTSSSSSEQRLLGSSFSSGPV----ADGIIRVQPKSELKPGELKPL
:: :: .:. :.::.:::: ::: : . :: .. ::.::: .: .::
CCDS37 TST---GSAASS-GSNSSASSEQGLLGRSPPTRPVPGHRSERAIRTQPK-QLIVDDLKGS
120 130 140 150 160
170 180 190 200 210 220
pF1KB9 SKEDLGLHAYRCEDCGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLF
:::: : . ::.:::::: ::: :: ::: :..::::::.....::::.: :::.:
CCDS37 LKEDLTQHKFICEQCGKCKCGECTAPRTLPSCLACNRQCLCSAESMVEYGTCMCLVKGIF
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB9 YHCSNDDE-DNCADNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDR
:::::::: :. .::::::::::::.:. ::.:::::::: :: :::::::::. :::
CCDS37 YHCSNDDEGDSYSDNPCSCSQSHCCSRYLCMGAMSLFLPCLLCYPPAKGCLKLCRRCYDW
230 240 250 260 270 280
290 300 310
pF1KB9 VNRPGCRCKNSNTVCCKVPTVPPRNFEKPT
..:::::::::::: ::. . : :. ::.
CCDS37 IHRPGCRCKNSNTVYCKLESCPSRGQGKPS
290 300 310
>>CCDS14769.4 SPRY3 gene_id:10251|Hs108|chrY (288 aa)
initn: 851 init1: 727 opt: 885 Z-score: 685.5 bits: 134.9 E(32554): 7.3e-32
Smith-Waterman score: 885; 46.4% identity (69.9% similar) in 289 aa overlap (39-313:11-286)
10 20 30 40 50 60
pF1KB9 NGSQPLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPTVVPRPGLK
..: ..:.:. . .:.:.: : : : .
CCDS14 MDAAVTDDFQQILPIEQLRSTHASNDYVERP---PAPCKQ
10 20 30
70 80 90 100 110 120
pF1KB9 PAPRPST---QHKHE-RLHGLPEHRQPPRLQHSQVHSSARAPLSRSISTVSSGSRSSTRT
:: :: . : .: :: . :: :. : : :...:.
CCDS14 ALSSPSLIVQTHKSDWSLATMPTSL--PR-SLSQCHQLQPLPQHLSQSSIASS------M
40 50 60 70 80
130 140 150 160 170
pF1KB9 STSSSSSEQRLLGSSFSSGPVADGIIRVQPKSELKP---GELKPLSKEDLGL---HAYRC
: :...:.:::: .:.. .: ...:::.:: . ..: : :: .... : : . :
CCDS14 SHSTTASDQRLL-ASITPSPSGQSIIRTQPGAGVHPKADGALKGEAEQSAGHPSEHLFIC
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB9 EDCGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSNDDEDNCA
:.::.::: :: ::::: :.:...:::::....:::::.:::::::::::.:::::::
CCDS14 EECGRCKCVPCTAARPLPSCWLCNQRCLCSAESLLDYGTCLCCVKGLFYHCSTDDEDNCA
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB9 DNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCK-NSN
:.::::. : : .::.::...::::::: ::::..:::.::: :: . ::::::: ..:
CCDS14 DEPCSCGPSSCFVRWAAMSLISLFLPCLCCYLPTRGCLHLCQQGYDSLRRPGCRCKRHTN
210 220 230 240 250 260
300 310
pF1KB9 TVCCKVPT--VP-PRNFEKPT
::: :. . .: :. ::
CCDS14 TVCRKISSGSAPFPKAQEKSV
270 280
>>CCDS14769.4 SPRY3 gene_id:10251|Hs108|chrX (288 aa)
initn: 851 init1: 727 opt: 885 Z-score: 685.5 bits: 134.9 E(32554): 7.3e-32
Smith-Waterman score: 885; 46.4% identity (69.9% similar) in 289 aa overlap (39-313:11-286)
10 20 30 40 50 60
pF1KB9 NGSQPLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPTVVPRPGLK
..: ..:.:. . .:.:.: : : : .
CCDS14 MDAAVTDDFQQILPIEQLRSTHASNDYVERP---PAPCKQ
10 20 30
70 80 90 100 110 120
pF1KB9 PAPRPST---QHKHE-RLHGLPEHRQPPRLQHSQVHSSARAPLSRSISTVSSGSRSSTRT
:: :: . : .: :: . :: :. : : :...:.
CCDS14 ALSSPSLIVQTHKSDWSLATMPTSL--PR-SLSQCHQLQPLPQHLSQSSIASS------M
40 50 60 70 80
130 140 150 160 170
pF1KB9 STSSSSSEQRLLGSSFSSGPVADGIIRVQPKSELKP---GELKPLSKEDLGL---HAYRC
: :...:.:::: .:.. .: ...:::.:: . ..: : :: .... : : . :
CCDS14 SHSTTASDQRLL-ASITPSPSGQSIIRTQPGAGVHPKADGALKGEAEQSAGHPSEHLFIC
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB9 EDCGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSNDDEDNCA
:.::.::: :: ::::: :.:...:::::....:::::.:::::::::::.:::::::
CCDS14 EECGRCKCVPCTAARPLPSCWLCNQRCLCSAESLLDYGTCLCCVKGLFYHCSTDDEDNCA
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB9 DNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCK-NSN
:.::::. : : .::.::...::::::: ::::..:::.::: :: . ::::::: ..:
CCDS14 DEPCSCGPSSCFVRWAAMSLISLFLPCLCCYLPTRGCLHLCQQGYDSLRRPGCRCKRHTN
210 220 230 240 250 260
300 310
pF1KB9 TVCCKVPT--VP-PRNFEKPT
::: :. . .: :. ::
CCDS14 TVCRKISSGSAPFPKAQEKSV
270 280
>>CCDS47296.1 SPRY4 gene_id:81848|Hs108|chr5 (299 aa)
initn: 795 init1: 401 opt: 830 Z-score: 643.7 bits: 127.2 E(32554): 1.5e-29
Smith-Waterman score: 854; 45.5% identity (68.1% similar) in 279 aa overlap (34-305:31-287)
10 20 30 40 50 60
pF1KB9 RAQSGNGSQPLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPTVVP
: . . .: .::... . :.: ..:...
CCDS47 MEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTILPIDQVKTSHVENDYIDNPSLA-
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 RPGLKPAPRPSTQHKHERLHGLPEHRQPPRLQHSQVHSSARAPLSRSISTVSSGSRSSTR
: .: :. : : :: : :: . . .: ..: :.
CCDS47 ---LTTGP------KRTR-GGAPELAPTP----------ARCDQDVTHHWISFSGRPSSV
60 70 80 90
130 140 150 160 170
pF1KB9 TSTSSSSSEQRLLGSSFSSGPVADGI----IRVQPKS-ELKPGELK-PLSKEDLGLHAYR
.:.::.::.:::: . .. :::: .:.::: . .: .:: : .: :
CCDS47 SSSSSTSSDQRLL-DHMAPPPVADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFLL
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB9 CEDCGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSN-DDEDN
:: :::::::::. :: ::: :.:...::::::....::::.: :.:.::::.: ::: .
CCDS47 CEACGKCKCKECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGS
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB9 CADNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCKNS
:::.:::::.:.::.::: ::..:. :::: ::::: ::.:: : :::. :::::::..
CCDS47 CADHPCSCSRSNCCARWSFMGALSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHT
220 230 240 250 260 270
300 310
pF1KB9 NTVCCKVPTVPPRNFEKPT
:.: ::. .
CCDS47 NSVICKAASGDAKTSRPDKPF
280 290
>>CCDS4274.1 SPRY4 gene_id:81848|Hs108|chr5 (322 aa)
initn: 795 init1: 401 opt: 830 Z-score: 643.3 bits: 127.2 E(32554): 1.6e-29
Smith-Waterman score: 854; 45.5% identity (68.1% similar) in 279 aa overlap (34-305:54-310)
10 20 30 40 50 60
pF1KB9 RAQSGNGSQPLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPTVVP
: . . .: .::... . :.: ..:...
CCDS42 MEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTILPIDQVKTSHVENDYIDNPSLA-
30 40 50 60 70 80
70 80 90 100 110 120
pF1KB9 RPGLKPAPRPSTQHKHERLHGLPEHRQPPRLQHSQVHSSARAPLSRSISTVSSGSRSSTR
: .: :. : : :: : :: . . .: ..: :.
CCDS42 ---LTTGP------KRTR-GGAPELAPTP----------ARCDQDVTHHWISFSGRPSSV
90 100 110 120
130 140 150 160 170
pF1KB9 TSTSSSSSEQRLLGSSFSSGPVADGI----IRVQPKS-ELKPGELK-PLSKEDLGLHAYR
.:.::.::.:::: . .. :::: .:.::: . .: .:: : .: :
CCDS42 SSSSSTSSDQRLL-DHMAPPPVADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFLL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 CEDCGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSN-DDEDN
:: :::::::::. :: ::: :.:...::::::....::::.: :.:.::::.: ::: .
CCDS42 CEACGKCKCKECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 CADNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCKNS
:::.:::::.:.::.::: ::..:. :::: ::::: ::.:: : :::. :::::::..
CCDS42 CADHPCSCSRSNCCARWSFMGALSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHT
250 260 270 280 290 300
300 310
pF1KB9 NTVCCKVPTVPPRNFEKPT
:.: ::. .
CCDS42 NSVICKAASGDAKTSRPDKPF
310 320
315 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 19:29:14 2016 done: Fri Nov 4 19:29:14 2016
Total Scan time: 3.020 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]