Result of FASTA (ccds) for
pFN21AB9747
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9747, 545 aa
1>>>pF1KB9747 545 - 545 aa - 545 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2680+/-0.000832; mu= 11.3607+/- 0.050
mean_var=138.1616+/-27.182, 0's: 0 Z-trim(112.7): 35 B-trim: 5 in 1/49
Lambda= 0.109114
statistics sampled from 13415 (13446) to 13415 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.744), E-opt: 0.2 (0.413), width: 16
Scan time: 3.840
The best scores are: opt bits E(32554)
CCDS11629.1 TBX4 gene_id:9496|Hs108|chr17 ( 545) 3739 599.9 2.5e-171
CCDS82180.1 TBX4 gene_id:9496|Hs108|chr17 ( 546) 3727 598.0 9.4e-171
CCDS9173.1 TBX5 gene_id:6910|Hs108|chr12 ( 518) 1710 280.5 3.4e-75
CCDS9174.1 TBX5 gene_id:6910|Hs108|chr12 ( 468) 1677 275.2 1.2e-73
CCDS13767.1 TBX1 gene_id:6899|Hs108|chr22 ( 495) 897 152.5 1.1e-36
CCDS11627.2 TBX2 gene_id:6909|Hs108|chr17 ( 712) 899 152.9 1.2e-36
CCDS13766.1 TBX1 gene_id:6899|Hs108|chr22 ( 398) 874 148.8 1.2e-35
CCDS13765.1 TBX1 gene_id:6899|Hs108|chr22 ( 372) 866 147.5 2.6e-35
CCDS9175.1 TBX3 gene_id:6926|Hs108|chr12 ( 723) 843 144.1 5.4e-34
CCDS31621.1 TBX10 gene_id:347853|Hs108|chr11 ( 385) 824 140.9 2.6e-33
CCDS10670.1 TBX6 gene_id:6911|Hs108|chr16 ( 436) 819 140.2 5e-33
CCDS43568.1 TBX20 gene_id:57057|Hs108|chr7 ( 447) 804 137.8 2.6e-32
CCDS34495.1 TBX18 gene_id:9096|Hs108|chr6 ( 607) 786 135.1 2.4e-31
CCDS81360.1 TBX15 gene_id:6913|Hs108|chr1 ( 602) 775 133.3 7.9e-31
CCDS30816.1 TBX15 gene_id:6913|Hs108|chr1 ( 496) 767 132.0 1.6e-30
CCDS14445.1 TBX22 gene_id:50945|Hs108|chrX ( 520) 724 125.2 1.8e-28
CCDS11514.1 TBX21 gene_id:30009|Hs108|chr17 ( 535) 713 123.5 6.2e-28
CCDS5290.1 T gene_id:6862|Hs108|chr6 ( 435) 689 119.7 7.2e-27
CCDS59045.1 T gene_id:6862|Hs108|chr6 ( 377) 674 117.3 3.3e-26
CCDS55960.1 MGA gene_id:23269|Hs108|chr15 (2856) 682 119.1 6.9e-26
CCDS55959.1 MGA gene_id:23269|Hs108|chr15 (3065) 682 119.2 7.3e-26
CCDS1272.1 TBX19 gene_id:9095|Hs108|chr1 ( 448) 653 114.0 3.8e-25
CCDS63585.1 EOMES gene_id:8320|Hs108|chr3 ( 705) 654 114.3 4.8e-25
CCDS33310.1 TBR1 gene_id:10716|Hs108|chr2 ( 682) 648 113.4 9e-25
CCDS2646.1 EOMES gene_id:8320|Hs108|chr3 ( 686) 642 112.4 1.7e-24
CCDS9176.1 TBX3 gene_id:6926|Hs108|chr12 ( 743) 551 98.1 3.8e-20
CCDS63584.1 EOMES gene_id:8320|Hs108|chr3 ( 410) 544 96.8 5.1e-20
>>CCDS11629.1 TBX4 gene_id:9496|Hs108|chr17 (545 aa)
initn: 3739 init1: 3739 opt: 3739 Z-score: 3189.3 bits: 599.9 E(32554): 2.5e-171
Smith-Waterman score: 3739; 100.0% identity (100.0% similar) in 545 aa overlap (1-545:1-545)
10 20 30 40 50 60
pF1KB9 MLQDKGLSESEEAFRAPGPALGEASAANAPEPALAAPGLSGAALGSPPGPGADVVAAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MLQDKGLSESEEAFRAPGPALGEASAANAPEPALAAPGLSGAALGSPPGPGADVVAAAAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 EQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 PADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 FGHIILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 FGHIILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 ENNPFAKGFRGSDDSDLRVARLQSKEYPVISKSIMRQRLISPQLSATPDVGPLLGTHQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ENNPFAKGFRGSDDSDLRVARLQSKEYPVISKSIMRQRLISPQLSATPDVGPLLGTHQAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 QHYQHENGAHSQLAEPQDLPLSTFPTQRDSSLFYHCLKRRDGTRHLDLPCKRSYLEAPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 QHYQHENGAHSQLAEPQDLPLSTFPTQRDSSLFYHCLKRRDGTRHLDLPCKRSYLEAPSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 VGEDHYFRSPPPYDQQMLSPSYCSEVTPREACMYSGSGPEIAGVSGVDDLPPPPLSCNMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 VGEDHYFRSPPPYDQQMLSPSYCSEVTPREACMYSGSGPEIAGVSGVDDLPPPPLSCNMW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 TSVSPYTSYSVQTMETVPYQPFPTHFTATTMMPRLPTLSAQSSQPPGNAHFSVYNQLSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TSVSPYTSYSVQTMETVPYQPFPTHFTATTMMPRLPTLSAQSSQPPGNAHFSVYNQLSQS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 QVRERGPSASFPRERGLPQGCERKPPSPHLNAANEFLYSQTFSLSRESSLQYHSGMGTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 QVRERGPSASFPRERGLPQGCERKPPSPHLNAANEFLYSQTFSLSRESSLQYHSGMGTVE
490 500 510 520 530 540
pF1KB9 NWTDG
:::::
CCDS11 NWTDG
>>CCDS82180.1 TBX4 gene_id:9496|Hs108|chr17 (546 aa)
initn: 2294 init1: 2294 opt: 3727 Z-score: 3179.0 bits: 598.0 E(32554): 9.4e-171
Smith-Waterman score: 3727; 99.8% identity (99.8% similar) in 546 aa overlap (1-545:1-546)
10 20 30 40 50 60
pF1KB9 MLQDKGLSESEEAFRAPGPALGEASAANAPEPALAAPGLSGAALGSPPGPGADVVAAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MLQDKGLSESEEAFRAPGPALGEASAANAPEPALAAPGLSGAALGSPPGPGADVVAAAAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 EQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 EQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 PADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 PADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 FGHIILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 FGHIILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 ENNPFAKGFRGSDDSDLRVARLQSKEYPVISKSIMRQRLISPQLSATPDVGPLLGTHQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 ENNPFAKGFRGSDDSDLRVARLQSKEYPVISKSIMRQRLISPQLSATPDVGPLLGTHQAL
250 260 270 280 290 300
310 320 330 340 350
pF1KB9 QHYQHENGAHSQLAEPQDLPLSTFPTQRDSSLFYHCLKRR-DGTRHLDLPCKRSYLEAPS
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
CCDS82 QHYQHENGAHSQLAEPQDLPLSTFPTQRDSSLFYHCLKRRADGTRHLDLPCKRSYLEAPS
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB9 SVGEDHYFRSPPPYDQQMLSPSYCSEVTPREACMYSGSGPEIAGVSGVDDLPPPPLSCNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SVGEDHYFRSPPPYDQQMLSPSYCSEVTPREACMYSGSGPEIAGVSGVDDLPPPPLSCNM
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB9 WTSVSPYTSYSVQTMETVPYQPFPTHFTATTMMPRLPTLSAQSSQPPGNAHFSVYNQLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 WTSVSPYTSYSVQTMETVPYQPFPTHFTATTMMPRLPTLSAQSSQPPGNAHFSVYNQLSQ
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB9 SQVRERGPSASFPRERGLPQGCERKPPSPHLNAANEFLYSQTFSLSRESSLQYHSGMGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SQVRERGPSASFPRERGLPQGCERKPPSPHLNAANEFLYSQTFSLSRESSLQYHSGMGTV
490 500 510 520 530 540
540
pF1KB9 ENWTDG
::::::
CCDS82 ENWTDG
>>CCDS9173.1 TBX5 gene_id:6910|Hs108|chr12 (518 aa)
initn: 1586 init1: 1297 opt: 1710 Z-score: 1463.4 bits: 280.5 E(32554): 3.4e-75
Smith-Waterman score: 1761; 54.0% identity (71.5% similar) in 554 aa overlap (7-544:1-516)
10 20 30 40 50
pF1KB9 MLQDKGLSESEEAF---RAP-GPALGEASAANAPEPALAAPGLSGAALGSPPGPGADVVA
.....:.: ..: : . . :: ::.::. :: .:
CCDS91 MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPS------KSPSSP-----Q
10 20 30 40
60 70 80 90 100 110
pF1KB9 AAAAEQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILL
:: ..: .:.::: :::.::: ::::.:::::::::::::::::::::::.:::::::::
CCDS91 AAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILL
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB9 IDIVPADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNN
.:::::::::::: :::: :.:::::::::::::::::::::::::::::::::::::::
CCDS91 MDIVPADDHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNN
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB9 HLDPFGHIILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVFPETSFISVTSYQNHKIT
:::::::::::::::::::::::::::::.::::::::::::::::.::.::::::::::
CCDS91 HLDPFGHIILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKIT
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB9 QLKIENNPFAKGFRGSDDSDL-RVARLQSKEYPVISKSIMRQRLISPQLSATPDVGPLLG
:::::::::::::::::: .: :..:.:::::::. .: .::.. : . . . :
CCDS91 QLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALST
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB9 THQALQHYQHENGAHSQLAEPQDL--PLSTFPTQRDSSLFYHCLKRRDGT-RHLDLPCKR
. . ..:: :::. . ::: : . .: .. : .::: ::.. : : :.
CCDS91 SSNLGSQYQCENGVSGP---SQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKK
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB9 SYLE-APSSVGEDHYFRSPPPYDQQMLSPSYCSEVTPREACMYSGSGPEIAGVSGVDDLP
:.: .:: :: ..:: : .:: :. :: .: . :.::::..:.: : ...:.
CCDS91 PYMETSPSE--EDSFYRSSYP-QQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDI-
350 360 370 380 390
420 430 440 450 460
pF1KB9 PPPLSCNMWTSVSPYTS---YSVQTMETVPYQPFPTHFTATTMMPRLPTLSAQSSQPPGN
::: : :. :.: .:: :. .::: : .:::. ..::: .. ..: :.
CCDS91 ----SCNTWPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGE
400 410 420 430 440 450
470 480 490 500 510 520
pF1KB9 AHFSVYNQLS-QSQVRERGPSASFPRERGLPQGCERKPPSPHLNAANEFLYSQTFSLSRE
. :. .... : ::. :: . :: . .:: :::::. .. :
CCDS91 GMFQHQTSVAHQPVVRQCGP------QTGLQSPGTLQPP--------EFLYSH--GVPRT
460 470 480 490
530 540
pF1KB9 -SSLQYHS--GMGTVENWTDG
: :::: :.: : .:.:
CCDS91 LSPHQYHSVHGVGMVPEWSDNS
500 510
>>CCDS9174.1 TBX5 gene_id:6910|Hs108|chr12 (468 aa)
initn: 1564 init1: 1275 opt: 1677 Z-score: 1435.9 bits: 275.2 E(32554): 1.2e-73
Smith-Waterman score: 1726; 57.3% identity (73.8% similar) in 492 aa overlap (64-544:1-466)
40 50 60 70 80 90
pF1KB9 LAAPGLSGAALGSPPGPGADVVAAAAAEQTIENIKVGLHEKELWKKFHEAGTEMIITKAG
.:.::: :::.::: ::::.::::::::::
CCDS91 MEGIKVFLHERELWLKFHEVGTEMIITKAG
10 20 30
100 110 120 130 140 150
pF1KB9 RRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPD
:::::::::::::.:::::::::.:::::::::::: :::: :.::::::::::::::::
CCDS91 RRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNKWSVTGKAEPAMPGRLYVHPD
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB9 SPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNAFGSKNTA
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
CCDS91 SPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNGFGSKNTA
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB9 FCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSDL-RVARLQSKEYPVISK
:::::::::.::.:::::::::::::::::::::::::::: .: :..:.:::::::. .
CCDS91 FCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPR
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB9 SIMRQRLISPQLSATPDVGPLLGTHQALQHYQHENGAHSQLAEPQDL--PLSTFPTQRDS
: .::.. : . . . : . . ..:: :::. . ::: : . .: ..
CCDS91 STVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSG---PSQDLLPPPNPYPLPQEH
220 230 240 250 260
340 350 360 370 380
pF1KB9 SLFYHCLKRRDGT-RHLDLPCKRSYLE-APSSVGEDHYFRSPPPYDQQMLSPSYCSEVTP
: .::: ::.. : : :. :.: .:: :: ..:: : .:: :. :: .: .
CCDS91 SQIYHCTKRKEEECSTTDHPYKKPYMETSPSE--EDSFYRSSYP-QQQGLGASYRTESAQ
270 280 290 300 310 320
390 400 410 420 430 440
pF1KB9 REACMYSGSGPEIAGVSGVDDLPPPPLSCNMWTSVSPYTS---YSVQTMETVPYQPFPTH
:.::::..:.: : ...:. ::: : :. :.: .:: :. .::: : .:
CCDS91 RQACMYASSAPPSEPVPSLEDI-----SCNTWPSMPSYSSCTVTTVQPMDRLPYQHFSAH
330 340 350 360 370
450 460 470 480 490 500
pF1KB9 FTATTMMPRLPTLSAQSSQPPGNAHFSVYNQLS-QSQVRERGPSASFPRERGLPQGCERK
::. ..::: .. ..: :.. :. .... : ::. :: . :: . .
CCDS91 FTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQCGP------QTGLQSPGTLQ
380 390 400 410 420 430
510 520 530 540
pF1KB9 PPSPHLNAANEFLYSQTFSLSRESSLQYHS--GMGTVENWTDG
:: :::::. . : :::: :.: : .:.:
CCDS91 PP--------EFLYSHGVPRTL-SPHQYHSVHGVGMVPEWSDNS
440 450 460
>>CCDS13767.1 TBX1 gene_id:6899|Hs108|chr22 (495 aa)
initn: 924 init1: 392 opt: 897 Z-score: 772.0 bits: 152.5 E(32554): 1.1e-36
Smith-Waterman score: 897; 47.6% identity (69.8% similar) in 315 aa overlap (16-320:60-362)
10 20 30 40
pF1KB9 MLQDKGLSESEEAFRAPGPALGEASAANAPEPALAAPGLSGAALG
:::: . :: : : . .: .
CCDS13 AASPGADPYGPREPPPPPPRYDPCAAAAPGAPGPPPPPHAYPFAP-----AAGAATSAAA
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB9 SPPGPGADVVAAAAA----EQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYK
: ::::. .::: : . . ...: :. : :: .:.. :::::.:::::::::...
CCDS13 EPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQ
90 100 110 120 130 140
110 120 130 140 150
pF1KB9 VKVTGMNPKTKYILLIDIVPADDHRYK--FCDNKWMVAGKAEPAMPGRLYVHPDSPATGA
::. ::.: . :.::.:.::.::.::. : ...:.:::::.:: :::.. :::::: ::
CCDS13 VKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGA
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB9 HWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKAD---ENNAFGSKNTAFCT
.::.:.:::.::::::: :: :::::::::.::::.:.: .: ... .. .: : :
CCDS13 QWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FKT
210 220 230 240 250 260
220 230 240 250 260 270
pF1KB9 HVFPETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSDL-RVARLQSKEYPVISKSIM
:: :: : .::.::::.:::::: .:::::::: : : : : :..: ..
CCDS13 FVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHR--PGALPLMS-AFA
270 280 290 300 310
280 290 300 310 320 330
pF1KB9 RQRLISPQLSATPDVGPLLGTHQALQHYQHENGAHSQLAEPQDLPLSTFPTQRDSSLFYH
:.: .: : : : . .: ...:.. :. . :..: :
CCDS13 RSR--NPVASPTQPSGTEKDAAEARREFQRDAGGPAVLGDPAHPPQLLARVLSPSLPGAG
320 330 340 350 360 370
340 350 360 370 380 390
pF1KB9 CLKRRDGTRHLDLPCKRSYLEAPSSVGEDHYFRSPPPYDQQMLSPSYCSEVTPREACMYS
CCDS13 GAGGLVPLPGAPGGRPSPPNPELRLEAPGASEPLHHHPYKYPAAAYDHYLGAKSRPAPYP
380 390 400 410 420 430
>>CCDS11627.2 TBX2 gene_id:6909|Hs108|chr17 (712 aa)
initn: 887 init1: 671 opt: 899 Z-score: 771.4 bits: 152.9 E(32554): 1.2e-36
Smith-Waterman score: 899; 57.9% identity (76.7% similar) in 240 aa overlap (17-254:53-290)
10 20 30 40
pF1KB9 MLQDKGLSESEEAFRAPGPALGEASAANAPEPALAAPGLSGAALGS
: :.:. :.:: : : : :: .:::
CCDS11 DFPMSAFLAAAQPSFFPALALPPGALAKPLPDPGLAGAAAAAAAAAAAAEAGLHVSALGP
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB9 -PPGPGADVVAAAAAEQTIEN-IKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKV
::. . . :. .:. :: :. :::: .::. ::::.:::.:::::: .::.:
CCDS11 HPPAAHLRSLKSLEPEDEVEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRV
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB9 TGMNPKTKYILLIDIVPADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQ
.:.. :.:::::.::: ::: :::: ...:::::::.: :: :.:.:::::::: .:: .
CCDS11 SGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAK
150 160 170 180 190 200
170 180 190 200 210 220
pF1KB9 LVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVFPETSF
:.:.::::::: : : :::::::::::.:::.: :. . ..: :.:::::.:
CCDS11 PVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRA--NDILKLPYSTFRTYVFPETDF
210 220 230 240 250 260
230 240 250 260 270 280
pF1KB9 ISVTSYQNHKITQLKIENNPFAKGFRGSDDSDLRVARLQSKEYPVISKSIMRQRLISPQL
:.::.::: :::::::.::::::::: . .
CCDS11 IAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLPSLRLYEEHCKPERDGAES
270 280 290 300 310 320
>>CCDS13766.1 TBX1 gene_id:6899|Hs108|chr22 (398 aa)
initn: 898 init1: 392 opt: 874 Z-score: 753.8 bits: 148.8 E(32554): 1.2e-35
Smith-Waterman score: 874; 50.0% identity (70.2% similar) in 292 aa overlap (16-297:60-339)
10 20 30 40
pF1KB9 MLQDKGLSESEEAFRAPGPALGEASAANAPEPALAAPGLSGAALG
:::: . :: : : . .: .
CCDS13 AASPGADPYGPREPPPPPPRYDPCAAAAPGAPGPPPPPHAYPFAP-----AAGAATSAAA
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB9 SPPGPGADVVAAAAA----EQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYK
: ::::. .::: : . . ...: :. : :: .:.. :::::.:::::::::...
CCDS13 EPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQ
90 100 110 120 130 140
110 120 130 140 150
pF1KB9 VKVTGMNPKTKYILLIDIVPADDHRYK--FCDNKWMVAGKAEPAMPGRLYVHPDSPATGA
::. ::.: . :.::.:.::.::.::. : ...:.:::::.:: :::.. :::::: ::
CCDS13 VKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGA
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB9 HWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKAD---ENNAFGSKNTAFCT
.::.:.:::.::::::: :: :::::::::.::::.:.: .: ... .. .: : :
CCDS13 QWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FKT
210 220 230 240 250 260
220 230 240 250 260 270
pF1KB9 HVFPETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSDL-RVARLQSKEYPVISKSIM
:: :: : .::.::::.:::::: .:::::::: : : : : :..: ..
CCDS13 FVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHR--PGALPLMS-AFA
270 280 290 300 310
280 290 300 310 320 330
pF1KB9 RQRLISPQLSATPDVGPLLGTHQALQHYQHENGAHSQLAEPQDLPLSTFPTQRDSSLFYH
:.: .: : : : : :
CCDS13 RSR--NPVASPTQPSGTEKGGHVLKDKEVKAETSRNTPEREVELLRDAGGCVNLGLPCPA
320 330 340 350 360 370
>>CCDS13765.1 TBX1 gene_id:6899|Hs108|chr22 (372 aa)
initn: 644 init1: 394 opt: 866 Z-score: 747.4 bits: 147.5 E(32554): 2.6e-35
Smith-Waterman score: 866; 50.0% identity (70.3% similar) in 290 aa overlap (16-295:60-337)
10 20 30 40
pF1KB9 MLQDKGLSESEEAFRAPGPALGEASAANAPEPALAAPGLSGAALG
:::: . :: : : . .: .
CCDS13 AASPGADPYGPREPPPPPPRYDPCAAAAPGAPGPPPPPHAYPFAP-----AAGAATSAAA
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB9 SPPGPGADVVAAAAA----EQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYK
: ::::. .::: : . . ...: :. : :: .:.. :::::.:::::::::...
CCDS13 EPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQ
90 100 110 120 130 140
110 120 130 140 150
pF1KB9 VKVTGMNPKTKYILLIDIVPADDHRYK--FCDNKWMVAGKAEPAMPGRLYVHPDSPATGA
::. ::.: . :.::.:.::.::.::. : ...:.:::::.:: :::.. :::::: ::
CCDS13 VKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGA
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB9 HWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKAD---ENNAFGSKNTAFCT
.::.:.:::.::::::: :: :::::::::.::::.:.: .: ... .. .: : :
CCDS13 QWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FKT
210 220 230 240 250 260
220 230 240 250 260 270
pF1KB9 HVFPETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSDL-RVARLQSKEYPVISKSIM
:: :: : .::.::::.:::::: .:::::::: : : : : :..: ..
CCDS13 FVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHR--PGALPLMS-AFA
270 280 290 300 310
280 290 300 310 320 330
pF1KB9 RQRLISPQLSATPDVGPLLGTHQALQHYQHENGAHSQLAEPQDLPLSTFPTQRDSSLFYH
:.: .: : : : :
CCDS13 RSR--NPVASPTQPSGTEKGLVTEGSGLQPGLLDVLLKPPSKKSESLRPPHCKDT
320 330 340 350 360 370
>>CCDS9175.1 TBX3 gene_id:6926|Hs108|chr12 (723 aa)
initn: 860 init1: 646 opt: 843 Z-score: 723.7 bits: 144.1 E(32554): 5.4e-34
Smith-Waterman score: 857; 52.4% identity (71.8% similar) in 273 aa overlap (17-278:42-308)
10 20 30 40
pF1KB9 MLQDKGLSESEEAFRAPGPALGEASAANAPEP-ALAAP---GLSGA
:. .: .:: : ::: : : ::
CCDS91 GTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALTLPPNGAAALSLPGALAKPIMDQLVGA
20 30 40 50 60 70
50 60 70 80 90
pF1KB9 ALGSPP----GPGADV--VAAAAAEQTIEN-IKVGLHEKELWKKFHEAGTEMIITKAGRR
: . : :: : . . . :. .:. :: :. :::: .::. ::::.:::.:::
CCDS91 AETGIPFSSLGPQAHLRPLKTMEPEEEVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRR
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB9 MFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSP
::: .::. .:.. :.:::::.::. ::: :::: ...:::::::.: :: :.:.:::::
CCDS91 MFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSP
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB9 ATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNAFGSKNTAFC
::: .:: ..:.:.::::::: : : :::::::::::.:::.: :. . ..:
CCDS91 ATGEQWMSKVVTFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRA--NDILKLPYSTFR
200 210 220 230 240
220 230 240 250 260 270
pF1KB9 THVFPETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSDLRVARLQSKEYPVISKSIM
:..:::: ::.::.::: :::::::.::::::::: : .. : : . :. . : ..
CCDS91 TYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFR--DTGNGR--REKRKQLTLQSMRVF
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB9 RQRLISPQLSATPDVGPLLGTHQALQHYQHENGAHSQLAEPQDLPLSTFPTQRDSSLFYH
.:
CCDS91 DERHKKENGTSDESSSEQAAFNCFAQASSPAASTVGTSNLKDLCPSEGESDAEAESKEEH
310 320 330 340 350 360
>>CCDS31621.1 TBX10 gene_id:347853|Hs108|chr11 (385 aa)
initn: 621 init1: 395 opt: 824 Z-score: 711.4 bits: 140.9 E(32554): 2.6e-33
Smith-Waterman score: 824; 39.9% identity (63.2% similar) in 378 aa overlap (16-381:13-374)
10 20 30 40 50 60
pF1KB9 MLQDKGLSESEEAFRAPGPALGEASAANAPEPALAAPGLSGAALGSPPGPGADVVAAAAA
::. . ..... :: :..: :: .: ::..:: ..
CCDS31 MAAFLSAGLGILAPSETYPLPTTSSGWEPRLGSPFPSGPCTSST---GAQAVAEPTG
10 20 30 40 50
70 80 90 100 110
pF1KB9 E----QTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILL
. . . : :. : ::..:.. :::::.::::::::: ..::. ::. . : ::
CCDS31 QGPKNPRVSRVTVQLEMKPLWEEFNQLGTEMIVTKAGRRMFPPFQVKILGMDSLADYALL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 IDIVPADDHRYK--FCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLT
.:..: ::.::. : .. :.:::::.:: :::.. :::::: ::.::::.:::.:::::
CCDS31 MDFIPLDDKRYRYAFHSSAWLVAGKADPATPGRVHFHPDSPAKGAQWMRQIVSFDKLKLT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 NNHLDPFGHIILNSMHKYQPRLHIVKAD---ENNAFGSKNTAFCTHVFPETSFISVTSYQ
:: :: :::::::::.::::.:.: .: ... ....: : . .: ::.: .::.::
CCDS31 NNLLDDNGHIILNSMHRYQPRFHVVFVDPRKDSERYAQEN--FKSFIFTETQFTAVTAYQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 NHKITQLKIENNPFAKGFRGSDDSDLRVARLQSKEYPVISKSIMRQRLISPQLSATPDVG
::.:::::: .:::::::: :: .. :: :. :.: . ... . : .
CCDS31 NHRITQLKIASNPFAKGFRESDLDSWPVAPRPLLSVPARSHSSLSPCVLKGATDREKDPN
240 250 260 270 280 290
300 310 320 330 340
pF1KB9 PLLGTHQALQHYQHENGAHSQLAEPQDL--PLSTFPTQRDSSLFYHCLKRRDGTRHLDLP
.. . . : :. : :. : : . :. .: .: . :: .:
CCDS31 KASASTSKTPAWLH----HQLLPPPEVLLAPATYRPVTYQS--LYS-----GAPSHLGIP
300 310 320 330 340
350 360 370 380 390 400
pF1KB9 CKR-SYLEAPSSVGEDHYFRSPPPYDQQMLSPSYCSEVTPREACMYSGSGPEIAGVSGVD
: . :. .. : : .:::.
CCDS31 RTRPAPYPLPNIRADRDQGGLPLPAGLGLLSPTVVCLGPGQDSQ
350 360 370 380
410 420 430 440 450 460
pF1KB9 DLPPPPLSCNMWTSVSPYTSYSVQTMETVPYQPFPTHFTATTMMPRLPTLSAQSSQPPGN
545 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 18:40:22 2016 done: Fri Nov 4 18:40:23 2016
Total Scan time: 3.840 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]