Result of FASTA (ccds) for
pFN21AB9691
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9691, 230 aa
1>>>pF1KB9691 230 - 230 aa - 230 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3046+/-0.000779; mu= 11.4331+/- 0.048
mean_var=128.5246+/-26.797, 0's: 0 Z-trim(112.7): 162 B-trim: 772 in 2/50
Lambda= 0.113131
statistics sampled from 13221 (13409) to 13221 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.755), E-opt: 0.2 (0.412), width: 16
Scan time: 2.410
The best scores are: opt bits E(32554)
CCDS5408.1 HOXA7 gene_id:3204|Hs108|chr7 ( 230) 1557 264.5 4.2e-71
CCDS11532.1 HOXB7 gene_id:3217|Hs108|chr17 ( 217) 806 141.9 3.2e-34
CCDS41792.1 HOXC6 gene_id:3223|Hs108|chr12 ( 153) 443 82.5 1.7e-16
CCDS8871.1 HOXC6 gene_id:3223|Hs108|chr12 ( 235) 443 82.7 2.3e-16
CCDS11531.1 HOXB6 gene_id:3216|Hs108|chr17 ( 224) 436 81.5 4.9e-16
CCDS8870.1 HOXC8 gene_id:3224|Hs108|chr12 ( 242) 435 81.4 5.8e-16
CCDS5406.1 HOXA5 gene_id:3202|Hs108|chr7 ( 270) 434 81.2 7.1e-16
CCDS11530.1 HOXB5 gene_id:3215|Hs108|chr17 ( 269) 431 80.8 9.9e-16
CCDS11533.1 HOXB8 gene_id:3218|Hs108|chr17 ( 243) 428 80.2 1.3e-15
CCDS56148.1 HOXD8 gene_id:3234|Hs108|chr2 ( 289) 429 80.5 1.3e-15
CCDS5407.1 HOXA6 gene_id:3203|Hs108|chr7 ( 233) 425 79.7 1.8e-15
CCDS56149.1 HOXD8 gene_id:3234|Hs108|chr2 ( 106) 410 76.9 5.5e-15
CCDS2268.1 HOXD8 gene_id:3234|Hs108|chr2 ( 290) 411 77.5 1e-14
CCDS8873.1 HOXC4 gene_id:3221|Hs108|chr12 ( 264) 400 75.7 3.3e-14
CCDS8872.1 HOXC5 gene_id:3222|Hs108|chr12 ( 222) 391 74.1 8e-14
CCDS11529.1 HOXB4 gene_id:3214|Hs108|chr17 ( 251) 377 71.9 4.2e-13
CCDS5405.1 HOXA4 gene_id:3201|Hs108|chr7 ( 320) 378 72.2 4.5e-13
CCDS2269.1 HOXD4 gene_id:3233|Hs108|chr2 ( 255) 376 71.8 4.8e-13
CCDS2267.2 HOXD9 gene_id:3235|Hs108|chr2 ( 352) 337 65.5 5e-11
>>CCDS5408.1 HOXA7 gene_id:3204|Hs108|chr7 (230 aa)
initn: 1557 init1: 1557 opt: 1557 Z-score: 1390.0 bits: 264.5 E(32554): 4.2e-71
Smith-Waterman score: 1557; 99.6% identity (100.0% similar) in 230 aa overlap (1-230:1-230)
10 20 30 40 50 60
pF1KB9 MSSSYYVNALFSKYTAGTSLFQNAEPTSCSFAPNSQRSGYGAGAGAFASTVPGLYNVNSP
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
CCDS54 MSSSYYVNALFSKYTAGASLFQNAEPTSCSFAPNSQRSGYGAGAGAFASTVPGLYNVNSP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LYQSPFASGYGLGADAYGNLPCASYDQNIPGLCSDLAKGACDKTDEGALHGAAEANFRIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LYQSPFASGYGLGADAYGNLPCASYDQNIPGLCSDLAKGACDKTDEGALHGAAEANFRIY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 PWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQN
130 140 150 160 170 180
190 200 210 220 230
pF1KB9 RRMKWKKEHKDEGPTAAAAPEGAVPSAAATAAADKADEEDDDEEEEDEEE
::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 RRMKWKKEHKDEGPTAAAAPEGAVPSAAATAAADKADEEDDDEEEEDEEE
190 200 210 220 230
>>CCDS11532.1 HOXB7 gene_id:3217|Hs108|chr17 (217 aa)
initn: 787 init1: 586 opt: 806 Z-score: 727.9 bits: 141.9 E(32554): 3.2e-34
Smith-Waterman score: 813; 58.4% identity (76.4% similar) in 233 aa overlap (1-224:1-217)
10 20 30 40 50
pF1KB9 MSSSYYVNALFSKYTAGTSLFQNA---EPTSCSFAPNSQRSGYGAGAGA-FASTVPGLYN
::: ::.:.::::: :..:.: .. : :::.:: : :: :::::.:: ::... :::
CCDS11 MSSLYYANTLFSKYPASSSVFATGAFPEQTSCAFASNPQRPGYGAGSGASFAASMQGLYP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 VNSPLY-QSP---FASGYGLGADAYGNLPCASYDQNIPGLC-SDLAKGACDKTDEGALHG
.. . :: .:.:::: ... :. :: ..::. :.: .: ::.: : .. .
CCDS11 GGGGMAGQSAAGVYAAGYGLEPSSF-NMHCAPFEQNLSGVCPGDSAKAAGAKEQRDS-DL
70 80 90 100 110
120 130 140 150 160 170
pF1KB9 AAEANFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTE
:::.:::::::::::: ::::::::::::::::::::::.::::::::::::::.:::::
CCDS11 AAESNFRIYPWMRSSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 RQIKIWFQNRRMKWKKEHKDEGPTAAAAPEGAVPSAAATAAADKADEEDDDEEEEDEEE
:::::::::::::::::.: :: .:.. :.:. :...::
CCDS11 RQIKIWFQNRRMKWKKENKTAGP--------------GTTGQDRAEAEEEEEE
180 190 200 210
>>CCDS41792.1 HOXC6 gene_id:3223|Hs108|chr12 (153 aa)
initn: 480 init1: 398 opt: 443 Z-score: 409.6 bits: 82.5 E(32554): 1.7e-16
Smith-Waterman score: 443; 57.3% identity (78.2% similar) in 124 aa overlap (114-229:35-153)
90 100 110 120 130
pF1KB9 SYDQNIPGLCSDLAKGACDKTDEGALHGAAEANFRIYPWMR--------SSGPDRKRGRQ
.:...:::::. . : ::.::::
CCDS41 CRQNTLGHNTQTSIAQDFSSEQGRTAPQDQKASIQIYPWMQRMNSHSGVGYGADRRRGRQ
10 20 30 40 50 60
140 150 160 170 180 190
pF1KB9 TYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEGPT
:.::::::::::::::::::::::::::.::::::::::::::::::::::: .
CCDS41 IYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKESN-----
70 80 90 100 110
200 210 220 230
pF1KB9 AAAAPEGAVPSAAATAAADKADEEDDDEEEEDEEE
... :. .:.: . . : ..... :::...:
CCDS41 LTSTLSGGGGGATADSLGGKEEKREETEEEKQKE
120 130 140 150
>>CCDS8871.1 HOXC6 gene_id:3223|Hs108|chr12 (235 aa)
initn: 504 init1: 398 opt: 443 Z-score: 407.2 bits: 82.7 E(32554): 2.3e-16
Smith-Waterman score: 477; 39.9% identity (65.0% similar) in 243 aa overlap (3-229:2-235)
10 20 30 40 50
pF1KB9 MSSSYYVNALFSKYTAG-TSLFQNAEPTSCSFAPNSQRSGYGAG-AGAFASTVPGLYNVN
.::..: .: . :: ... :. .: .. : . : :::. : ..: .:
CCDS88 MNSYFTNPSLSCHLAGGQDVLPNVALNSTAYDPVRHFSTYGAAVAQNRIYSTP-FY---
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 SPLYQSPFASGYG---LGADAYGNLP--CASYDQNIPGLCSDLAKGACDKTDEGALHGAA
:: . :.:. : :.... . .. :: : .. . . ....:
CCDS88 SPQENVVFSSSRGPYDYGSNSFYQEKDMLSNCRQNTLGHNTQTSIAQDFSSEQGRTAPQD
60 70 80 90 100 110
120 130 140 150 160
pF1KB9 E-ANFRIYPWMR--------SSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIA
. :...:::::. . : ::.:::: :.::::::::::::::::::::::::::
CCDS88 QKASIQIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIA
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB9 HALCLTERQIKIWFQNRRMKWKKEHKDEGPTAAAAPEGAVPSAAATAAADKADEEDDDEE
.::::::::::::::::::::::: . ... :. .:.: . . : ..... ::
CCDS88 NALCLTERQIKIWFQNRRMKWKKE-----SNLTSTLSGGGGGATADSLGGKEEKREETEE
180 190 200 210 220 230
230
pF1KB9 EEDEEE
:...:
CCDS88 EKQKE
>>CCDS11531.1 HOXB6 gene_id:3216|Hs108|chr17 (224 aa)
initn: 491 init1: 410 opt: 436 Z-score: 401.3 bits: 81.5 E(32554): 4.9e-16
Smith-Waterman score: 481; 44.9% identity (57.3% similar) in 227 aa overlap (3-201:2-217)
10 20 30 40 50
pF1KB9 MSSSYYVNALFSKYTA-GTSLFQNAEPTSCSFAPNSQR---SGYGAGAG---AFASTVPG
:::.::. : : : : . : : . : . :: : : .::..
CCDS11 MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPGPGQDKGFATSS--
10 20 30 40 50
60 70 80 90 100
pF1KB9 LYNVNSPLYQSPFASGYGLGADA-YGNLP---------CA-SYDQNIPGLCSDLAKGAC-
: : ..::: .: :: : :: : .. : . . :. :
CCDS11 --------YYPPAGGGYGRAAPCDYGPAPAFYREKESACALSGADEQPPFHPEPRKSDCA
60 70 80 90 100
110 120 130 140 150
pF1KB9 -DKTDEGALHGAAEANFRIYPWMR--------SSGPDRKRGRQTYTRYQTLELEKEFHFN
::. : . . . .::::. : ::. .:::::::::::::::::::.:
CCDS11 QDKSVFGETE-EQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYN
110 120 130 140 150 160
160 170 180 190 200 210
pF1KB9 RYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEGPTAAAAPEGAVPSAAATAA
:::::::::::::::::::::::::::::::::::: : . . .: :
CCDS11 RYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQAE
170 180 190 200 210 220
220 230
pF1KB9 ADKADEEDDDEEEEDEEE
>>CCDS8870.1 HOXC8 gene_id:3224|Hs108|chr12 (242 aa)
initn: 537 init1: 389 opt: 435 Z-score: 400.0 bits: 81.4 E(32554): 5.8e-16
Smith-Waterman score: 508; 42.5% identity (61.0% similar) in 259 aa overlap (3-230:2-236)
10 20 30 40 50
pF1KB9 MSSSYYVNALFSKYTAGTSLFQNAEPT--SCSFAPNSQRSG---YGAGAGAFASTVPGLY
:::.:: ::::: :: :: ::. .: : . :: :: :..: ::.
CCDS88 MSSYFVNPLFSKYKAGESL----EPAYYDCRFPQSVGRSHALVYGPGGSA-----PGFQ
10 20 30 40 50
60 70 80 90
pF1KB9 NVNSPLYQSPFASGY-GLGADAYGNLPCA-----------SYD----QNIPGLCS-----
.. : :. : : :.. ..: . ::. .:. :.. : .
CCDS88 HA-SHHVQDFFHHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVV
60 70 80 90 100
100 110 120 130 140 150
pF1KB9 ---DLAKGACDKTDEGALHGAAEANFRI-YPWMRSSGPDRKRGRQTYTRYQTLELEKEFH
: ..: ...:: : ... . .:::: .: :. :::::.:::::::::::
CCDS88 QYPDCKSSANTNSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFL
110 120 130 140 150 160
160 170 180 190 200
pF1KB9 FNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH-KDEGPTAAAAPEGAVPSAAA
:: ::::.::::..::: :::::.::::::::::::::. ::. : .: :
CCDS88 FNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLP--GARDE--------
170 180 190 200 210
210 220 230
pF1KB9 TAAADKADEEDDDEEEEDEEE
.:..:: ..:::..:::
CCDS88 ----EKVEEEGNEEEEKEEEEKEENKD
220 230 240
>>CCDS5406.1 HOXA5 gene_id:3202|Hs108|chr7 (270 aa)
initn: 483 init1: 403 opt: 434 Z-score: 398.5 bits: 81.2 E(32554): 7.1e-16
Smith-Waterman score: 447; 42.5% identity (62.0% similar) in 221 aa overlap (5-199:47-264)
10 20
pF1KB9 MSSSYYVNAL-FSKYTAGTSLFQNAE-----PTS
: :.. .: .:.. : ..: .:
CCDS54 PDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSGSGHFGSGERARSYAAS
20 30 40 50 60 70
30 40 50 60 70 80
pF1KB9 CSFAPNSQRSGYGAGAGAFASTVPGLYNVNSPLYQSPFASGYGLGADAYGNLPCASYDQN
: :: : :. : . : : : . :: .... : .. .: :: : .
CCDS54 ASAAPAEPR--YSQPATSTHSPQPDPLPC-SAVAPSPGSDSHHGGKNSLSNSSGASADAG
80 90 100 110 120 130
90 100 110 120
pF1KB9 IPGLCS----DLAKGACDKTDEGALHGAAE--------ANFRIYPWMRS--------SGP
. : :.:: . . .. ...:. :. .::::::. .::
CCDS54 STHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYPWMRKLHISHDNIGGP
140 150 160 170 180 190
130 140 150 160 170 180
pF1KB9 DRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKE
. ::.: .:::::::::::::::::::::::::::::::::.:::::::::::::::::.
CCDS54 EGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKD
200 210 220 230 240 250
190 200 210 220 230
pF1KB9 HKDEGPTAAAAPEGAVPSAAATAAADKADEEDDDEEEEDEEE
.: .. . :::
CCDS54 NKLKSMSMAAAGGAFRP
260 270
>>CCDS11530.1 HOXB5 gene_id:3215|Hs108|chr17 (269 aa)
initn: 493 init1: 401 opt: 431 Z-score: 395.9 bits: 80.8 E(32554): 9.9e-16
Smith-Waterman score: 433; 43.7% identity (65.5% similar) in 197 aa overlap (21-205:85-269)
10 20 30 40
pF1KB9 MSSSYYVNALFSKYTAGTSLFQNAEPTSCSFA-PNSQRSGYGAGAGAFAS
:..: .:::.. :.: : . :: :
CCDS11 SVNRSSASSSHFGAVGESSRAFPAPAQEPRFRQAA-SSCSLSSPESLPCTNGDSHGAKPS
60 70 80 90 100 110
50 60 70 80 90 100
pF1KB9 TVPGLYNVNSPLYQSPFASGYGLGADAYGNLPCASYDQNIPGLCSDLAKGACDKTDEGAL
. .:: :. ::. . . .. :: ... :.:.. . ... .
CCDS11 A-------SSPSDQATSASS----SANFTEIDEASASSEPEEAASQLSSPSLARAQPEPM
120 130 140 150 160
110 120 130 140 150
pF1KB9 HGAAEA----NFRIYPWMRS-------SGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRR
.. : . .:.::::. .::: ::.: .::::::::::::::::::::::
CCDS11 ATSTAAPEGQTPQIFPWMRKLHISHDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRR
170 180 190 200 210 220
160 170 180 190 200 210
pF1KB9 RRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEGPTAAAAPEGAVPSAAATAAADKADE
:::::::::::.:::::::::::::::::..: .. . :.: . :
CCDS11 RRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSLATAGSAFQP
230 240 250 260
220 230
pF1KB9 EDDDEEEEDEEE
>>CCDS11533.1 HOXB8 gene_id:3218|Hs108|chr17 (243 aa)
initn: 478 init1: 353 opt: 428 Z-score: 393.8 bits: 80.2 E(32554): 1.3e-15
Smith-Waterman score: 496; 43.1% identity (63.8% similar) in 246 aa overlap (3-224:2-243)
10 20 30 40 50
pF1KB9 MSSSYYVNALFSKYTAGTSLFQNAEPTSCSFAPN-SQRSG--YG-AGAGAFA--STVPGL
:::.::.::::: .: :: : .:.:: . . : :: ...:.: : . .
CCDS11 MSSYFVNSLFSKYKTGESLRPNYY--DCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEF
10 20 30 40 50
60 70 80 90 100
pF1KB9 YNVNS-----PLYQSPFASG-YGLGADAYGNLPCASYDQNIPGLCS-DLAKGA-CDKTDE
:. : : :.: : . .: .. :: : :.. : . ::.. : : .
CCDS11 YHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQR--QSLFGAQDPDLVQYADCKLAAA
60 70 80 90 100 110
110 120 130 140 150
pF1KB9 GALHGAAEAN------FRIYPWMR-SSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRR
..: ::.. ...:::: ... :.::::::.::::::::::: :: ::::.:
CCDS11 SGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKR
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB9 RIEIAHALCLTERQIKIWFQNRRMKWKKEH-KDEGPTAAAAPEGAVPSAAATA--AADKA
:::..::: :::::.::::::::::::::. ::. :.. : . : :::..
CCDS11 RIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADEG
180 190 200 210 220 230
220 230
pF1KB9 DEEDDDEEEEDEEE
: . :..
CCDS11 DAQKGDKK
240
>>CCDS56148.1 HOXD8 gene_id:3234|Hs108|chr2 (289 aa)
initn: 469 init1: 396 opt: 429 Z-score: 393.7 bits: 80.5 E(32554): 1.3e-15
Smith-Waterman score: 429; 41.8% identity (63.5% similar) in 189 aa overlap (39-217:97-285)
10 20 30 40 50 60
pF1KB9 ALFSKYTAGTSLFQNAEPTSCSFAPNSQRSGYGAGAGAFASTVPGLYNVNSPLYQSPFA-
: :. :.:. .. : . : : .
CCDS56 QAHAHPHPSPPPSGTGCGGREGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPPPPPCGG
70 80 90 100 110 120
70 80 90 100 110 120
pF1KB9 -SGYGLGADAYG--NL---PCASYDQNIPGLCSDLAKGACDKTDEGALH-GAAEANFRIY
. .: : :: :: : . .:. . :.. . : : . . . ...
CCDS56 IACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMF
130 140 150 160 170 180
130 140 150 160 170 180
pF1KB9 PWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQN
:::: ..: :.::::::.:.::::::::: :: ::::.::::..::: :::::.::::::
CCDS56 PWMRPQAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQN
190 200 210 220 230 240
190 200 210 220 230
pF1KB9 RRMKWKKEH-KDEGPTA-AAAPEGAVPSAAATAAADKADEEDDDEEEEDEEE
::::::::. ::. :.. . .: . . : :.:.
CCDS56 RRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN
250 260 270 280
230 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 18:21:37 2016 done: Fri Nov 4 18:21:38 2016
Total Scan time: 2.410 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]