Result of FASTA (omim) for
pFN21AB9653
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9653, 276 aa
1>>>pF1KB9653 276 - 276 aa - 276 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.2220+/-0.000359; mu= 3.5606+/- 0.022
mean_var=216.0047+/-45.684, 0's: 0 Z-trim(121.3): 175 B-trim: 1754 in 1/56
Lambda= 0.087266
statistics sampled from 37575 (37768) to 37575 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.768), E-opt: 0.2 (0.443), width: 16
Scan time: 7.460
The best scores are: opt bits E(85289)
NP_009015 (OMIM: 604974) transcription factor SOX- ( 276) 1856 245.6 7.5e-65
NP_004180 (OMIM: 604747) transcription factor SOX- ( 240) 664 95.5 1e-19
NP_003097 (OMIM: 184429,189960,206900) transcripti ( 317) 620 90.1 5.7e-18
NP_005977 (OMIM: 602148) transcription factor SOX- ( 391) 611 89.0 1.5e-17
NP_005625 (OMIM: 300123,312000,313430) transcripti ( 446) 602 87.9 3.5e-17
NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapi ( 233) 471 71.2 2e-12
NP_003098 (OMIM: 184430) transcription factor SOX- ( 474) 456 69.6 1.3e-11
NP_008874 (OMIM: 601947) transcription factor SOX- ( 315) 439 67.3 4.1e-11
NP_055402 (OMIM: 605923) transcription factor SOX- ( 446) 428 66.0 1.4e-10
NP_000337 (OMIM: 114290,608160,616425) transcripti ( 509) 423 65.5 2.4e-10
NP_003131 (OMIM: 400044,400045,480000) sex-determi ( 204) 409 63.3 4.1e-10
NP_003099 (OMIM: 600898,615866) transcription fact ( 441) 415 64.4 4.3e-10
NP_008872 (OMIM: 602229,609136,611584,613266) tran ( 466) 410 63.8 6.9e-10
NP_071899 (OMIM: 610928,613674) transcription fact ( 414) 402 62.7 1.3e-09
NP_060889 (OMIM: 137940,601618,607823) transcripti ( 384) 398 62.2 1.7e-09
NP_113627 (OMIM: 612202) transcription factor SOX- ( 388) 365 58.1 3.1e-08
NP_821078 (OMIM: 604975,616803) transcription fact ( 377) 331 53.8 5.8e-07
XP_011519144 (OMIM: 604975,616803) PREDICTED: tran ( 415) 331 53.8 6.2e-07
XP_005245680 (OMIM: 604748) PREDICTED: transcripti ( 621) 331 54.0 8.3e-07
NP_005677 (OMIM: 604748) transcription factor SOX- ( 622) 331 54.0 8.3e-07
NP_001248343 (OMIM: 604975,616803) transcription f ( 642) 331 54.0 8.5e-07
XP_016875389 (OMIM: 604975,616803) PREDICTED: tran ( 715) 331 54.0 9.2e-07
XP_016875388 (OMIM: 604975,616803) PREDICTED: tran ( 715) 331 54.0 9.2e-07
XP_016875390 (OMIM: 604975,616803) PREDICTED: tran ( 715) 331 54.0 9.2e-07
XP_016875387 (OMIM: 604975,616803) PREDICTED: tran ( 715) 331 54.0 9.2e-07
XP_016875386 (OMIM: 604975,616803) PREDICTED: tran ( 716) 331 54.0 9.2e-07
NP_001317714 (OMIM: 604975,616803) transcription f ( 728) 331 54.0 9.3e-07
XP_011519140 (OMIM: 604975,616803) PREDICTED: tran ( 729) 331 54.0 9.4e-07
XP_016875385 (OMIM: 604975,616803) PREDICTED: tran ( 750) 331 54.0 9.5e-07
NP_694534 (OMIM: 604975,616803) transcription fact ( 750) 331 54.0 9.5e-07
XP_016875379 (OMIM: 604975,616803) PREDICTED: tran ( 751) 331 54.0 9.6e-07
XP_011519136 (OMIM: 604975,616803) PREDICTED: tran ( 751) 331 54.0 9.6e-07
XP_016875381 (OMIM: 604975,616803) PREDICTED: tran ( 751) 331 54.0 9.6e-07
XP_011519139 (OMIM: 604975,616803) PREDICTED: tran ( 751) 331 54.0 9.6e-07
XP_011519137 (OMIM: 604975,616803) PREDICTED: tran ( 751) 331 54.0 9.6e-07
XP_016875383 (OMIM: 604975,616803) PREDICTED: tran ( 751) 331 54.0 9.6e-07
XP_016875380 (OMIM: 604975,616803) PREDICTED: tran ( 751) 331 54.0 9.6e-07
XP_016875382 (OMIM: 604975,616803) PREDICTED: tran ( 751) 331 54.0 9.6e-07
XP_016875384 (OMIM: 604975,616803) PREDICTED: tran ( 751) 331 54.0 9.6e-07
NP_001248344 (OMIM: 604975,616803) transcription f ( 753) 331 54.0 9.6e-07
XP_011519135 (OMIM: 604975,616803) PREDICTED: tran ( 754) 331 54.0 9.6e-07
NP_008871 (OMIM: 604975,616803) transcription fact ( 763) 331 54.0 9.7e-07
XP_011519134 (OMIM: 604975,616803) PREDICTED: tran ( 764) 331 54.0 9.7e-07
XP_016875378 (OMIM: 604975,616803) PREDICTED: tran ( 792) 331 54.1 9.9e-07
XP_016875377 (OMIM: 604975,616803) PREDICTED: tran ( 793) 331 54.1 9.9e-07
NP_001139283 (OMIM: 607257) transcription factor S ( 801) 325 53.3 1.7e-06
NP_059978 (OMIM: 607257) transcription factor SOX- ( 804) 325 53.3 1.7e-06
NP_201583 (OMIM: 607257) transcription factor SOX- ( 808) 325 53.3 1.7e-06
NP_001139291 (OMIM: 607257) transcription factor S ( 841) 325 53.3 1.7e-06
XP_011532722 (OMIM: 606698) PREDICTED: transcripti ( 448) 299 49.8 1.1e-05
>>NP_009015 (OMIM: 604974) transcription factor SOX-21 [ (276 aa)
initn: 1856 init1: 1856 opt: 1856 Z-score: 1285.3 bits: 245.6 E(85289): 7.5e-65
Smith-Waterman score: 1856; 100.0% identity (100.0% similar) in 276 aa overlap (1-276:1-276)
10 20 30 40 50 60
pF1KB9 MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 AKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 AKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 AGGGLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 AGGGLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 EISSSSSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EISSSSSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNC
190 200 210 220 230 240
250 260 270
pF1KB9 SAWPSPGLQPPLAYILLPGMGKPQLDPYPAAYAAAL
::::::::::::::::::::::::::::::::::::
NP_009 SAWPSPGLQPPLAYILLPGMGKPQLDPYPAAYAAAL
250 260 270
>>NP_004180 (OMIM: 604747) transcription factor SOX-14 [ (240 aa)
initn: 1046 init1: 627 opt: 664 Z-score: 475.1 bits: 95.5 E(85289): 1e-19
Smith-Waterman score: 978; 57.9% identity (73.7% similar) in 285 aa overlap (1-276:1-240)
10 20 30 40 50 60
pF1KB9 MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDE
:::: ::.::::::::::::.::::::::::::::::::::::::::::.:.::::.:::
NP_004 MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 AKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAG
::::::.:::::::::::::::::.:::::...::.:: :: :.. : ::: ::: .:
NP_004 AKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPY-LG---DTD-P-LKA-AGLPVG
70 80 90 100 110
130 140 150 160 170
pF1KB9 AGGGLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLGS---
:. :: :. :::: :.:.: ..: :::::: ..
NP_004 ASDGL-----LSAPEKA---------RAFLPPASA-------------PYSLLDPAQFSS
120 130 140
180 190 200 210 220 230
pF1KB9 ----KMAEISSS--SSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGN
::.:. . ...:::::.::: . ::: :. . . :::.:::: :
NP_004 SAIQKMGEVPHTLATGALPYASTLGYQN---GAF-GSLSCPSQ-------HTHTHPSPTN
150 160 170 180 190
240 250 260 270
pF1KB9 PGYMIPCNCSAWPSPGLQPPLAYILLPGMGKPQLDPYPAAYAAAL
:::..::::.:: . ::::.::::.::: : .::: .:.:.:.
NP_004 PGYVVPCNCTAWSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM
200 210 220 230 240
>>NP_003097 (OMIM: 184429,189960,206900) transcription f (317 aa)
initn: 624 init1: 569 opt: 620 Z-score: 443.6 bits: 90.1 E(85289): 5.7e-18
Smith-Waterman score: 620; 43.0% identity (62.9% similar) in 272 aa overlap (6-269:39-304)
10 20 30
pF1KB9 MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHN
:.:::::::::::::.::::::::::::::
NP_003 LKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHN
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 SEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFP
::::::::::::::.:.::::::::::::::.::::::::::::::: :::.::::...:
NP_003 SEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLP
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB9 VPYGLGGVADAEHPALKAGAGLHAGAGGGLVP--ESLLANPEKAAAAAAAAAARVFFPQS
::. .. .:.:. :: :.:. .: . .. . .. .::
NP_003 -----GGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLGYPQH
130 140 150 160 170 180
160 170 180 190 200
pF1KB9 AAAAAAAAAAAAAGSPYSLLDLG-SKMAEISSSSSGLP-YA---SSLGYPTAGAGAFHGA
. : .:: :.. : ..:. .. .: : :. :. : : . :.. :.
NP_003 PGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYSMSYSQQGTPGMALGSM-GS
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB9 AAAAAAAAAAAGGHTHSHP-SPGNPGYMIPCNCSAWPSPGLQPPLAYILLPGMGKPQLDP
.. . :... . :: .: . : . :. . : : : . : :
NP_003 VVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSRLHMSQHYQSGP
250 260 270 280 290 300
270
pF1KB9 YPAAYAAAL
:
NP_003 VPGTAINGTLPLSHM
310
>>NP_005977 (OMIM: 602148) transcription factor SOX-1 [H (391 aa)
initn: 742 init1: 555 opt: 611 Z-score: 436.3 bits: 89.0 E(85289): 1.5e-17
Smith-Waterman score: 684; 46.2% identity (64.9% similar) in 305 aa overlap (6-258:49-349)
10 20 30
pF1KB9 MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHN
:.:::::::::::::.::::::::::::::
NP_005 PTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHN
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB9 SEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFP
::::::::::::...:.::::::::::::::.::::::::::::::: ::::::::...
NP_005 SEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLKKDKYSLA
80 90 100 110 120 130
100 110 120 130
pF1KB9 ---VPYGLGGVADAEHPALKAGAGLHA----------GAGGGLVPESLLAN---PEKAAA
. : :: . : .. .:.: : .:::: . . :: : ..::
NP_005 GGLLAAGAGGGGAAVAMGVGVGVGAAAVGQRLESPGGAAGGGYAHVNGWANGAYPGSVAA
140 150 160 170 180 190
140 150 160 170 180
pF1KB9 AAAAAA----ARVFFPQSAAAAAAAAAAAAAG-------------SPYSLLDLGS-KMAE
:::::: :.. . : .:..: : : .:. :.:. ...
NP_005 AAAAAAMMQEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAHPHNPQPMHRYDMGALQYSP
200 210 220 230 240 250
190 200 210 220
pF1KB9 ISSSSS----------GLPYASSLGYPTAGAGAFHGAAAAAAAAAAAA--------GGHT
::.:.. ::::... . .:..:: ...:.::::::::: :. .
NP_005 ISNSQGYMSASPSGYGGLPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLV
260 270 280 290 300 310
230 240 250 260 270
pF1KB9 HSHPSPGNPGYMIPCNCSAWPSPGLQPPLAYILLPGMGKPQLDPYPAAYAAAL
.:.:: . :. : . : : :: . . ::
NP_005 KSEPSGSPPA---PAHSRA-PCPGDLREMISMYLPAGEGGDPAAAAAAAAQSRLHSLPQH
320 330 340 350 360 370
NP_005 YQGAGAGVNGTVPLTHI
380 390
>>NP_005625 (OMIM: 300123,312000,313430) transcription f (446 aa)
initn: 565 init1: 565 opt: 602 Z-score: 429.4 bits: 87.9 E(85289): 3.5e-17
Smith-Waterman score: 612; 48.2% identity (66.3% similar) in 249 aa overlap (6-232:137-383)
10 20 30
pF1KB9 MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHN
:.:::::::::::::.:::::: :::::::
NP_005 GKSSANAAGGANSGGGSSGGASGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHN
110 120 130 140 150 160
40 50 60 70 80 90
pF1KB9 SEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFP
:::::::::.:::::..::::::::::::::.::::.:::::::::: ::::::::...:
NP_005 SEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLP
170 180 190 200 210 220
100 110 120 130 140 150
pF1KB9 VPYGLGGVADAEHPALKAGAGLHAGAGGGLVPESLLANPEKAAAAAAAAAARVFFPQSAA
:.: : : :.:. . .: : .. : .: . . .. . : .
NP_005 SGLLPPGAAAAAAAAAAAAAAASSPVGVGQRLDTYTHVNGWANGAYSLVQEQLGYAQPPS
230 240 250 260 270 280
160 170 180 190 200
pF1KB9 AAAAAAAAA--------AAGSPYS-LLDLGSK----MAEISSSSSGLPYASSLGYPTAGA
.. : :: :: .. :.. .: ....:: :.. ::.:
NP_005 MSSPPPPPALPPMHRYDMAGLQYSPMMPPGAQSYMNVAAAAAAASG--YGGMAPSATAAA
290 300 310 320 330 340
210 220 230 240 250
pF1KB9 GAFHG---AAAAAAAAAAAA------GGHTHSHPSPGNPGYMIPCNCSAWPSPGLQPPLA
.: .: :.:::::::::: :. ..:.:: :
NP_005 AAAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAIASHSQRACLGDLRDMISMY
350 360 370 380 390 400
260 270
pF1KB9 YILLPGMGKPQLDPYPAAYAAAL
NP_005 LPPGGDAADAASPLPGGRLHGVHQHYQGAGTAVNGTVPLTHI
410 420 430 440
>>NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapiens] (233 aa)
initn: 476 init1: 458 opt: 471 Z-score: 343.9 bits: 71.2 E(85289): 2e-12
Smith-Waterman score: 474; 43.6% identity (62.7% similar) in 204 aa overlap (4-202:45-226)
10 20 30
pF1KB9 MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKM
:...:::::::::::: ::::.:::.::::
NP_008 EPPAATAAASSSSGPQEREGAGSPAAPGTLPLEKVKRPMNAFMVWSSAQRRQMAQQNPKM
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB9 HNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFA
:::::::::::.:::: :.:::::..::::::: :....:::::::::: :.
NP_008 HNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDYKYRPRRKAKS--------
80 90 100 110 120
100 110 120 130 140 150
pF1KB9 FPVPYGLGGVADAEHPALKAGAGLHAGAGGGLV--PESLLANPEKAAAAAAAAAARVFFP
: : :. . : : :.:: . : ..: .. . . . ...:
NP_008 ----SGAG-------PS-RCGQGRGNLASGGPLWGPGYATTQPSRGFGYRPPSYSTAYLP
130 140 150 160 170
160 170 180 190 200
pF1KB9 QSAAAAAAAAAAAAAGS-PYSLLDLGSKMAEISSSSSGLPYASSLGY--PTAGAGAFHGA
: ... : . : : : : ... . . . :: .: : : :::
NP_008 GSYGSSHCKLEAPSPCSLPQSDPRLQGEL--LPTYTHYLPPGSPTPYNPPLAGAPMPLTH
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB9 AAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNCSAWPSPGLQPPLAYILLPGMGKPQLDPY
NP_008 L
>>NP_003098 (OMIM: 184430) transcription factor SOX-4 [H (474 aa)
initn: 505 init1: 393 opt: 456 Z-score: 329.7 bits: 69.6 E(85289): 1.3e-11
Smith-Waterman score: 464; 40.2% identity (65.2% similar) in 244 aa overlap (4-222:55-287)
10 20 30
pF1KB9 MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKM
: :.:::::::::::. .:::. ...: :
NP_003 GLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDM
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB9 HNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFA
::.::::::: .:::: .:.: ::: ::.::: :: ..::::::::.: :. ... .
NP_003 HNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVKSGNANSSSS
90 100 110 120 130 140
100 110 120 130
pF1KB9 F-----PVPYG--LGGVADAEHPALKAGAGLHAGAGGGLV--------PESLLANPEKAA
: : .:: . . : . .:.. .::.::: . : . . :.:
NP_003 AAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVA
150 160 170 180 190 200
140 150 160 170 180
pF1KB9 AAAAAAA----ARVFFP------QSAAAAAAAAAAAAAGSPYSLLDLGSKMAEISSSSSG
..:.... :.... ..::::::. :: ::. .:: ::. ... .
NP_003 GGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAEQAGAA-ALLPLGA-----AADHHS
210 220 230 240 250
190 200 210 220 230 240
pF1KB9 LPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNCSAWPSPGL
: : . :.:.:.: ..::.:.:: :: : :
NP_003 LYKART---PSASASA--SSAASASAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGVG
260 270 280 290 300 310
250 260 270
pF1KB9 QPPLAYILLPGMGKPQLDPYPAAYAAAL
NP_003 AGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRGYASLRAASPAPSS
320 330 340 350 360 370
>>NP_008874 (OMIM: 601947) transcription factor SOX-12 [ (315 aa)
initn: 487 init1: 385 opt: 439 Z-score: 320.4 bits: 67.3 E(85289): 4.1e-11
Smith-Waterman score: 439; 34.4% identity (58.2% similar) in 273 aa overlap (4-265:36-295)
10 20 30
pF1KB9 MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKM
: :.:::::::::::. .:::. .. : :
NP_008 GARAKRDGGPPPPGPGPAEEGAREPGWCKTPSGHIKRPMNAFMVWSQHERRKIMDQWPDM
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 HNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFA
::.::::::: .:.:: .::: ::. ::.::: :: ..::::::::.: : : :
NP_008 HNAEISKRLGRRWQLLQDSEKIPFVREAERLRLKHMADYPDYKYRPRKKSKGAPAK---A
70 80 90 100 110 120
100 110 120 130 140
pF1KB9 FPVPYGLGGVADAEHPALK-AGAGLHAGAGGGL-----VPESLLANPEKAAAAA--AAAA
: : : .: .. .:. . : : . .::: : .::. . .. . . .
NP_008 RPRPPGGSGGGSRLKPGPQLPGRGGRRAAGGPLGGGAAAPEDDDEDDDEELLEVRLVETP
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB9 ARVFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMAEISSSSSGLPYASSLGYPTAGAGAF
.: .. . :. :: . : : .: . .. : . : . : .:.:
NP_008 GRELWRMVPAGRAARGQAERAQGPSGEGAAAAAAASPTPSEDEEPEEEE----EEAAAAE
190 200 210 220 230
210 220 230 240 250 260
pF1KB9 HGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNCSAWP-SPGLQPP--LAYILLPGMGK
.: ..:.. . : .. :.:.. .::: .: :::: ... .: .
NP_008 EGEEETVASGEESLGFLSRLPPGPAG------LDCSALDRDPDLQPPSGTSHFEFPDYCT
240 250 260 270 280 290
270
pF1KB9 PQLDPYPAAYAAAL
:..
NP_008 PEVTEMIAGDWRPSSIADLVFTY
300 310
>>NP_055402 (OMIM: 605923) transcription factor SOX-8 [H (446 aa)
initn: 466 init1: 393 opt: 428 Z-score: 311.0 bits: 66.0 E(85289): 1.4e-10
Smith-Waterman score: 428; 34.4% identity (58.0% similar) in 262 aa overlap (2-247:98-346)
10 20 30
pF1KB9 MSKPVDHVKRPMNAFMVWSRAQRRKMAQENP
.:: ::::::::::::..: :::.:.. :
NP_055 IRDAVSQVLKGYDWSLVPMPVRGGGGGALKAKP--HVKRPMNAFMVWAQAARRKLADQYP
70 80 90 100 110 120
40 50 60 70 80
pF1KB9 KMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLL---K
..::.:.:: :: :.::.:::::::..::.:::..: :.::::::.:::. ..
NP_055 HLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSAKAGHSD
130 140 150 160 170 180
90 100 110 120 130 140
pF1KB9 KDKFAFPVPYGLGGVADAEHPALKAGA--GLHAGAGGGLVPESLLANPEKAAAAAAAAAA
.:. : :. ::.. . .: : : :.: : : . ..:. :.:
NP_055 SDSGAELGPHPGGGAVYKAEAGLGDGHHHGDHTGQTHG--PPTPPTTPKTELQQAGAK--
190 200 210 220 230 240
150 160 170 180 190
pF1KB9 RVFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMAEISSSSSGLPYAS-----SLGYPT--
:. . . .. . .: .:.. .:. .. ... :: :.
NP_055 ----PELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDAFDVHEFDQYLPLGGPAPP
250 260 270 280 290
200 210 220 230 240 250
pF1KB9 ----AGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNCSAWPSPGLQPPLAYI
: .::. :.:. . : .: . . : : : : . ::::
NP_055 EPGQAYGGAYFHAGASPVWAHKSAPSASASPTETGPPR---PHIKTEQPSPGHYGDQPRG
300 310 320 330 340 350
260 270
pF1KB9 LLPGMGKPQLDPYPAAYAAAL
NP_055 SPDYGSCSGQSSATPAAPAGPFAGSQGDYGDLQASSYYGAYPGYAPGLYQYPCFHSPRRP
360 370 380 390 400 410
>>NP_000337 (OMIM: 114290,608160,616425) transcription f (509 aa)
initn: 422 init1: 396 opt: 423 Z-score: 306.9 bits: 65.5 E(85289): 2.4e-10
Smith-Waterman score: 433; 32.5% identity (55.4% similar) in 289 aa overlap (2-271:99-364)
10 20 30
pF1KB9 MSKPVDHVKRPMNAFMVWSRAQRRKMAQENP
:: ::::::::::::..: :::.:.. :
NP_000 FPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYP
70 80 90 100 110 120
40 50 60 70 80 90
pF1KB9 KMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDK
..::.:.:: :: :.::.:::::::..::.:::..: :.::::::.:::. :.. . .
NP_000 HLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRR-KSVKNGQA
130 140 150 160 170 180
100 110 120 130
pF1KB9 FAFPV-------PYGLGGVADAEHPALKAGA------GLHAGAGGGLVPESLLANPEKAA
: . : .. . .:. : ..: : :.: . : : . ..:. .
NP_000 EAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQG--PPTPPTTPKTDV
190 200 210 220 230 240
140 150 160 170 180 190
pF1KB9 AAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMAEISSSSSGLP------YA
. : : : .. . .:.: ... :. . :
NP_000 QPGKADLKREGRPLPEGGRQPPI-------DFRDVDIGELSSDVISNIETFDVNEFDQYL
250 260 270 280 290
200 210 220 230 240 250
pF1KB9 SSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNCSAWPSPGLQPPL
:.: :. : :: .. ... : . . .:.. :.. . .: : : :::
NP_000 PPNGHP--GVPATHGQVTYTGSY-----GISSTAATPASAGHVWMSKQQAPPPPPQQPPQ
300 310 320 330 340 350
260 270
pF1KB9 AYILLPGMGKPQLDPYPAAYAAAL
: :. :: : : :
NP_000 AP---PA---PQAPPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPS
360 370 380 390 400
276 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 17:59:14 2016 done: Fri Nov 4 17:59:15 2016
Total Scan time: 7.460 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]