Result of FASTA (omim) for
pFN21AB9434
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9434, 216 aa
1>>>pF1KB9434 216 - 216 aa - 216 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1126+/-0.000344; mu= 14.2329+/- 0.021
mean_var=56.8581+/-11.371, 0's: 0 Z-trim(113.5): 18 B-trim: 195 in 1/51
Lambda= 0.170090
statistics sampled from 22913 (22931) to 22913 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.269), width: 16
Scan time: 5.820
The best scores are: opt bits E(85289)
NP_775739 (OMIM: 609282) MOB kinase activator 1B i ( 216) 838 213.6 1.9e-55
XP_005265766 (OMIM: 609282) PREDICTED: MOB kinase ( 221) 838 213.6 2e-55
NP_001231695 (OMIM: 609282) MOB kinase activator 1 ( 221) 838 213.6 2e-55
XP_011530714 (OMIM: 609282) PREDICTED: MOB kinase ( 240) 838 213.7 2.1e-55
XP_016864326 (OMIM: 609282) PREDICTED: MOB kinase ( 247) 838 213.7 2.2e-55
NP_001304039 (OMIM: 609281) MOB kinase activator 1 ( 215) 836 213.1 2.7e-55
NP_060691 (OMIM: 609281) MOB kinase activator 1A i ( 216) 835 212.9 3.2e-55
NP_001304040 (OMIM: 609281) MOB kinase activator 1 ( 258) 835 212.9 3.8e-55
NP_001231696 (OMIM: 609282) MOB kinase activator 1 ( 147) 528 137.5 1.1e-32
NP_001304041 (OMIM: 609281) MOB kinase activator 1 ( 138) 527 137.2 1.2e-32
XP_011531250 (OMIM: 609281) PREDICTED: MOB kinase ( 180) 527 137.3 1.6e-32
NP_001165694 (OMIM: 611969) MOB kinase activator 2 ( 268) 429 113.3 3.8e-25
NP_443731 (OMIM: 611969) MOB kinase activator 2 is ( 237) 419 110.8 1.9e-24
NP_001094289 (OMIM: 609361) MOB-like protein phoce ( 204) 203 57.8 1.5e-08
NP_056202 (OMIM: 609361) MOB-like protein phocein ( 225) 195 55.9 6.3e-08
NP_001191023 (OMIM: 609361) MOB-like protein phoce ( 193) 185 53.4 3e-07
NP_955776 (OMIM: 609361) MOB-like protein phocein ( 193) 185 53.4 3e-07
>>NP_775739 (OMIM: 609282) MOB kinase activator 1B isofo (216 aa)
initn: 848 init1: 740 opt: 838 Z-score: 1116.3 bits: 213.6 E(85289): 1.9e-55
Smith-Waterman score: 838; 55.4% identity (82.7% similar) in 202 aa overlap (13-214:11-211)
10 20 30 40 50 60
pF1KB9 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWV
:::.::... :....:: :.:.:.:.:: .:. ::.:: ::: :.::
NP_775 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEWV
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 AVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNL
::..:::::.::..:::: .::::..:::::.::::::.: : . ::: ::.:..
NP_775 AVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 LMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEA
:: :.. :...: .::. .::::::::... : :: :::::..:.: .::: :: . ::
NP_775 LMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEA
120 130 140 150 160 170
190 200 210
pF1KB9 HVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH
:.:: .::: .:: :.:::::.:: ::.:. ..
NP_775 HLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
180 190 200 210
>>XP_005265766 (OMIM: 609282) PREDICTED: MOB kinase acti (221 aa)
initn: 848 init1: 740 opt: 838 Z-score: 1116.1 bits: 213.6 E(85289): 2e-55
Smith-Waterman score: 838; 55.4% identity (82.7% similar) in 202 aa overlap (13-214:16-216)
10 20 30 40 50
pF1KB9 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQN
:::.::... :....:: :.:.:.:.:: .:. ::.:: ::: :
XP_005 MEGATDVNESGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLN
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 DWVAVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQY
.::::..:::::.::..:::: .::::..:::::.::::::.: : . ::: ::.:
XP_005 EWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 MNLLMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMG
.. :: :.. :...: .::. .::::::::... : :: :::::..:.: .::: :: .
XP_005 IDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQ
120 130 140 150 160 170
180 190 200 210
pF1KB9 AEAHVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH
:::.:: .::: .:: :.:::::.:: ::.:. ..
XP_005 EEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
180 190 200 210 220
>>NP_001231695 (OMIM: 609282) MOB kinase activator 1B is (221 aa)
initn: 848 init1: 740 opt: 838 Z-score: 1116.1 bits: 213.6 E(85289): 2e-55
Smith-Waterman score: 838; 55.4% identity (82.7% similar) in 202 aa overlap (13-214:16-216)
10 20 30 40 50
pF1KB9 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQN
:::.::... :....:: :.:.:.:.:: .:. ::.:: ::: :
NP_001 MEGATDVNESGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLN
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 DWVAVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQY
.::::..:::::.::..:::: .::::..:::::.::::::.: : . ::: ::.:
NP_001 EWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 MNLLMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMG
.. :: :.. :...: .::. .::::::::... : :: :::::..:.: .::: :: .
NP_001 IDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQ
120 130 140 150 160 170
180 190 200 210
pF1KB9 AEAHVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH
:::.:: .::: .:: :.:::::.:: ::.:. ..
NP_001 EEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
180 190 200 210 220
>>XP_011530714 (OMIM: 609282) PREDICTED: MOB kinase acti (240 aa)
initn: 848 init1: 740 opt: 838 Z-score: 1115.5 bits: 213.7 E(85289): 2.1e-55
Smith-Waterman score: 838; 55.4% identity (82.7% similar) in 202 aa overlap (13-214:35-235)
10 20 30 40
pF1KB9 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGV
:::.::... :....:: :.:.:.:.::
XP_011 RVDRGAGQPRRTRWASSLAAEETRSGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 DLKAAVQLPSGEDQNDWVAVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQD
.:. ::.:: ::: :.::::..:::::.::..:::: .::::..:::::.::::::.: :
XP_011 NLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWAD
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB9 DLKYKKPTALPAPQYMNLLMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVF
. ::: ::.:.. :: :.. :...: .::. .::::::::... : :: :::::.
XP_011 GTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVY
130 140 150 160 170 180
170 180 190 200 210
pF1KB9 VHVYIHHFDRVIVMGAEAHVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH
.:.: .::: :: . :::.:: .::: .:: :.:::::.:: ::.:. ..
XP_011 AHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
190 200 210 220 230 240
>>XP_016864326 (OMIM: 609282) PREDICTED: MOB kinase acti (247 aa)
initn: 848 init1: 740 opt: 838 Z-score: 1115.4 bits: 213.7 E(85289): 2.2e-55
Smith-Waterman score: 838; 55.4% identity (82.7% similar) in 202 aa overlap (13-214:42-242)
10 20 30 40
pF1KB9 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGV
:::.::... :....:: :.:.:.:.::
XP_016 SFDFPGSGDPFISNPLPATSSWYYSGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB9 DLKAAVQLPSGEDQNDWVAVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQD
.:. ::.:: ::: :.::::..:::::.::..:::: .::::..:::::.::::::.: :
XP_016 NLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWAD
80 90 100 110 120 130
110 120 130 140 150 160
pF1KB9 DLKYKKPTALPAPQYMNLLMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVF
. ::: ::.:.. :: :.. :...: .::. .::::::::... : :: :::::.
XP_016 GTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVY
140 150 160 170 180 190
170 180 190 200 210
pF1KB9 VHVYIHHFDRVIVMGAEAHVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH
.:.: .::: :: . :::.:: .::: .:: :.:::::.:: ::.:. ..
XP_016 AHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
200 210 220 230 240
>>NP_001304039 (OMIM: 609281) MOB kinase activator 1A is (215 aa)
initn: 845 init1: 737 opt: 836 Z-score: 1113.6 bits: 213.1 E(85289): 2.7e-55
Smith-Waterman score: 836; 53.4% identity (82.2% similar) in 208 aa overlap (8-214:4-210)
10 20 30 40 50
pF1KB9 MSIALKQVFNKD-KTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDW
.:... :::.::... :....:: :.:.:.:.:: .:. ::.:: ::: :.:
NP_001 MSFLFSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRQAVMLPEGEDLNEW
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 VAVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMN
.::..:::::.::..:::: ::::: .:::::.::.:::.: : . ::: ::.:..
NP_001 IAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYID
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 LLMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAE
:: :.. :...: .::. .::::::::... : :: :::::..:.: .::: :. . :
NP_001 YLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEE
120 130 140 150 160 170
180 190 200 210
pF1KB9 AHVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH
::.:: .::: .:: :.:::::.:: ::.:. ..
NP_001 AHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
180 190 200 210
>>NP_060691 (OMIM: 609281) MOB kinase activator 1A isofo (216 aa)
initn: 845 init1: 737 opt: 835 Z-score: 1112.3 bits: 212.9 E(85289): 3.2e-55
Smith-Waterman score: 835; 54.5% identity (82.2% similar) in 202 aa overlap (13-214:11-211)
10 20 30 40 50 60
pF1KB9 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWV
:::.::... :....:: :.:.:.:.:: .:. ::.:: ::: :.:.
NP_060 MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRQAVMLPEGEDLNEWI
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 AVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNL
::..:::::.::..:::: ::::: .:::::.::.:::.: : . ::: ::.:..
NP_060 AVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 LMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEA
:: :.. :...: .::. .::::::::... : :: :::::..:.: .::: :. . ::
NP_060 LMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEA
120 130 140 150 160 170
190 200 210
pF1KB9 HVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH
:.:: .::: .:: :.:::::.:: ::.:. ..
NP_060 HLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
180 190 200 210
>>NP_001304040 (OMIM: 609281) MOB kinase activator 1A is (258 aa)
initn: 845 init1: 737 opt: 835 Z-score: 1111.1 bits: 212.9 E(85289): 3.8e-55
Smith-Waterman score: 835; 54.5% identity (82.2% similar) in 202 aa overlap (13-214:53-253)
10 20 30 40
pF1KB9 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGV
:::.::... :....:: :.:.:.:.::
NP_001 SRIVLSSSDSAHLLALILTNFSCPRSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB9 DLKAAVQLPSGEDQNDWVAVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQD
.:. ::.:: ::: :.:.::..:::::.::..:::: ::::: .:::::.::.:::.: :
NP_001 NLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWAD
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB9 DLKYKKPTALPAPQYMNLLMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVF
. ::: ::.:.. :: :.. :...: .::. .::::::::... : :: :::::.
NP_001 GTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVY
150 160 170 180 190 200
170 180 190 200 210
pF1KB9 VHVYIHHFDRVIVMGAEAHVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH
.:.: .::: :. . :::.:: .::: .:: :.:::::.:: ::.:. ..
NP_001 AHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
210 220 230 240 250
>>NP_001231696 (OMIM: 609282) MOB kinase activator 1B is (147 aa)
initn: 538 init1: 430 opt: 528 Z-score: 707.8 bits: 137.5 E(85289): 1.1e-32
Smith-Waterman score: 528; 53.5% identity (83.7% similar) in 129 aa overlap (13-141:11-138)
10 20 30 40 50 60
pF1KB9 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWV
:::.::... :....:: :.:.:.:.:: .:. ::.:: ::: :.::
NP_001 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEWV
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 AVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNL
::..:::::.::..:::: .::::..:::::.::::::.: : . ::: ::.:..
NP_001 AVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 LMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEA
:: :.. :...: .::. .:.
NP_001 LMTWVQDQLDDETLFPSKIGIINFCKGDPS
120 130 140
>>NP_001304041 (OMIM: 609281) MOB kinase activator 1A is (138 aa)
initn: 525 init1: 438 opt: 527 Z-score: 706.9 bits: 137.2 E(85289): 1.2e-32
Smith-Waterman score: 527; 53.5% identity (82.9% similar) in 129 aa overlap (13-141:11-138)
10 20 30 40 50 60
pF1KB9 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWV
:::.::... :....:: :.:.:.:.:: .:. ::.:: ::: :.:.
NP_001 MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRQAVMLPEGEDLNEWI
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 AVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNL
::..:::::.::..:::: ::::: .:::::.::.:::.: : . ::: ::.:..
NP_001 AVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 LMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEA
:: :.. :...: .::. .::
NP_001 LMTWVQDQLDDETLFPSKIGV
120 130
216 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 17:02:31 2016 done: Fri Nov 4 17:02:32 2016
Total Scan time: 5.820 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]